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Dietary supplement

Thyme Leaf Extract Ingredients & Drug Interactions

by Nature's Answer

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Thyme Leaf Extract is a dietary supplement by Nature's Answer with 1 active ingredient. Its ingredients are commonly taken for cough and respiratory congestion, sore throat, digestive upset.Based on those ingredients, 379 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Thyme Leaf Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Thyme Leaf Extract by Nature's Answer

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product is a liquid extract containing one active ingredient: thyme leaf extract. The formula also includes glycerin, purified water, and alcohol as inactive ingredients that help deliver and preserve the extract.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Thyme product and its label doesn't state a use — see Thyme's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold on thyme for the conditions listed—bronchitis, aging skin, alopecia areata, and common cold—rates as insufficient. That means current research doesn't give us enough reliable data to say whether thyme actually works for these uses.

If you're considering this product for a specific reason, talk with your doctor or pharmacist about what the broader evidence shows and whether it's a fit for your situation.

The evidence, ingredient by ingredient Thyme

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Thyme used in food amounts is generally well tolerated, and medicinal oral use seems well tolerated too. Topically, it's generally well tolerated as well.

The most common side effects when taken by mouth are allergic reactions, diarrhea, dizziness, headache, heartburn, nausea, or vomiting. On skin, contact dermatitis and irritation can occur—thymol (a thyme component) in toothpastes has been linked to lip and tongue inflammation.

Important: the concentrated essential oil can be toxic if swallowed, and medicinal or essential-oil amounts lack enough safety data, so stick to food amounts unless your doctor approves a higher dose. Pregnancy and lactation data rates this as likely safe, but confirm with your own doctor before use during pregnancy or while breastfeeding.

Side effects, ingredient by ingredient Thyme

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Thyme.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 379 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before starting thyme if you take blood thinners or antiplatelet drugs (like warfarin, aspirin, or clopidogrel)—thyme may add to their effects. Also confirm use if you take estrogen replacement therapy, anticholinergic drugs (for overactive bladder or certain movement disorders), or cholinergic drugs (for low muscle tone, myasthenia gravis, or glaucoma).

Altogether, these interactions span 379 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Thyme leaf extract is well tolerated at food amounts and has a long history in cooking and teas. If you take blood thinners, hormone replacement, or certain nerve-signaling medications, you'll want to check with your doctor or pharmacist before adding this—even though the risks are theoretical, they're worth ruling out.

Evidence for its effectiveness against bronchitis, colds, skin aging, or hair loss isn't established in our data, so weigh that against any reason you're considering it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Thyme Leaf Extract, straight from the product label.

Brand Nature's Answer
Barcode (UPC) 083000005213
Net contents 1 fl. Oz.; 30 mL
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 264126
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Kosher, Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Thyme Leaf Extract by Nature's Answer, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
30
UPC/BARCODE
083000005213
IngredientAmount% DV
Thyme Leaf Extract400 mg--

Other ingredients: Glycerin, Water, Purified, Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Gluten Free

Bio-Chelated Cold Extraction Process

Absolutely No Preservatives

Our alcohol extracts are produced using our cold Bio-Chelated proprietary extraction process, yielding a Holistically Balanced Advanced Botanical Fingerprint extract in the same synergistic ratios as in the play.

Seals/Symbols

K Parve (Kosher)

Formula

K Parve (Kosher)

Thymus vulgaris Made from 1,000 mg Thyme Leaf per serving

Low Alcohol

Brand IP Statement(s)

Nature's Answer Since 1972

Discover Nature's Answer

Copyright 2018 Nature's Answer

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1 mL (28 drops) three (3) times a day in a small amount of water. Shake well.

Precautions

Keep out of reach of children.

Warning: Do not use if pregnant or nursing.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

General Statements

For product information, call (800)439-2324

See for yourself

Thyme Leaf Extract by Nature's Answer label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Thyme Leaf Extract by Nature's Answer

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Thyme Leaf Extract

Interacts with
379 drugs
400 mg per serving Form: Thymus vulgaris Leaf Extract

Thyme is a common kitchen herb that has long been used for coughs, sore throats, and digestive complaints. It is generally safe in the amounts found i...

Thyme Leaf Extract monograph & interactions

Other (inactive) ingredients: Glycerin, Water, Purified, Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Thyme Leaf Extract by Nature's Answer Drug Interactions

Want to check YOUR meds against Thyme Leaf Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
379Drugs
379 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Thyme Leaf Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Thyme Leaf Extract4 drug types · 379 drugs

Anticholinergic Drugs

Theoretically, concurrent use of anticholinergic drugs and thyme essential oil might reduce the effects of anticholinergic drugs.
In vitro evidence suggests that thyme essential oil and specific essential oil constituents like thymohydroquinone and carvacrol can inhibit acetylcholinesterase (AChE). However, this effect has not been observed in humans.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, thyme leaf extract might have additive effects with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that thyme leaf extract has antiplatelet effects. However, this effect has not been observed in humans.

Likelihood Possible Evidence D
Cholinergic Drugs

Theoretically, concurrent use of cholinergic drugs and thyme essential oil might cause additive cholinergic effects.
In vitro evidence suggests that thyme essential oil and specific essential oil constituents like thymohydroquinone and carvacrol can inhibit acetylcholinesterase (AChE). However, this effect has not been observed in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, thyme might competitively inhibit the effects of estrogen replacement therapy.
In vitro research shows that thyme has estrogen receptor-binding activity and phytoestrogen content. However, this effect has not been observed in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Thyme Leaf Extract, from the product label.

Nature's Answer

See all Nature's Answer products
Name
Nature's Answer
Street Address
85 Commerce Drive
City
Hauppauge
State
NY
ZipCode
11788
Phone Number
(800) 439-2324
Web Address
www.naturesanswer.com
Pharmacist Counseling Corner

Thyme Leaf Extract by Nature's Answer: Common Questions

Does Thyme Leaf Extract by Nature's Answer interact with any medications?
Yes. Based on its ingredients, Thyme Leaf Extract has a known interaction with 379 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Thyme Leaf Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use this thyme extract if I'm pregnant or breastfeeding?
Thyme leaf extract rates as likely safe in pregnancy and lactation based on the data we hold. That said, confirm with your own doctor or pharmacist before starting any supplement during pregnancy or while breastfeeding—they'll know your full picture best.
What are the most common side effects?
When taken by mouth, thyme is generally well tolerated, but some people report allergic reactions, diarrhea, dizziness, headache, heartburn, nausea, or vomiting. Applied to skin, it can cause contact dermatitis or irritation in sensitive people.
Is this the same as thyme essential oil?
No—this is a leaf extract in liquid form. The concentrated essential oil is very different and can be toxic if swallowed, so stick to food amounts or this extract unless your doctor says otherwise.
Does this really help with colds or cough?
The evidence we hold on thyme for common cold and bronchitis rates as insufficient—we don't have enough reliable data to say whether it works. If you're considering it for respiratory symptoms, talk with your doctor about what fits your situation.
Will this interfere with my birth control?
Thyme may theoretically weaken estrogen-based therapies like birth control through lab mechanisms, though this hasn't been proven in people. If you use hormonal birth control, mention this product to your doctor or pharmacist before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Thyme Leaf Extract is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Thyme Leaf Extract label
Go deeper

The Full Monographs Behind Thyme Leaf Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Thyme Leaf Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 18 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Thyme 18 references
  1. Zava DT, Dollbaum CM, Blen M. Estrogen and progestin bioactivity of foods, herbs, and spices. Proc Soc Exp Biol Med 1998;217:369-78. PubMed
  2. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  3. Okazaki K, Kawazoe K, Takaishi Y. Human platelet aggregation inhibitors from thyme (Thymus vulgaris L.). Phytother Res 2002;16:398-9. .
  4. Spiewak R, Skorska C, Dutkiewicz J. Occupational airborne contact dermatitis caused by thyme dust. Contact Dermatitis 2001;44:235-9. . PubMed
  5. Ernst E, Marz R, Sieder C. A controlled multi-centre study of herbal versus synthetic secretolytic drugs for acute bronchitis. Phytomedicine 1997;4:287-93. PubMed
  6. Yamamoto J, Yamada K, Naemura A, et al. Testing various herbs for antithrombotic effect. Nutrition 2005;21(5):580-7. PubMed
  7. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  8. Mackiewicz, B., Skorska, C., Dutkiewicz, J., Michnar, M., Milanowski, J., Prazmo, Z., Krysinska-Traczyk, E., and Cisak, E. Allergic alveolitis due to herb dust exposure. Ann Agric Environ Med 1999;6(2):167-170.
  9. Martinez-Gonzalez, M. C., Goday Bujan, J. J., Martinez, Gomez W., and Fonseca, Capdevila E. Concomitant allergic contact dermatitis due to Rosmarinus officinalis (rosemary) and Thymus vulgaris (thyme). Contact Dermatitis 2007;56(1):49-50.
  10. Jukic, M., Politeo, O., Maksimovic, M., Milos, M., and Milos, M. In vitro acetylcholinesterase inhibitory properties of thymol, carvacrol and their derivatives thymoquinone and thymohydroquinone. Phytother.Res 2007;21(3):259-261.
  11. Marzian, O. [Treatment of acute bronchitis in children and adolescents. Non-interventional postmarketing surveillance study confirms the benefit and safety of a syrup made of extracts from thyme and ivy leaves]. MMW.Fortschr.Med 6-28-2007;149(27-28 Suppl
  12. Cuzzolin, L. and Benoni, G. Attitudes and knowledge toward natural products safety in the pharmacy setting: an Italian study. Phytother.Res 2009;23(7):1018-1023. PubMed
  13. Berova, N., Stransky, L., and Krasteva, M. Studies on contact dermatitis in stomatological staff. Dermatol.Monatsschr. 1990;176(1):15-18.
  14. Smeenk, G., Kerckhoffs, H. P., and Schreurs, P. H. Contact allergy to a reaction product in Hirudoid cream: an example of compound allergy. Br.J Dermatol. 1987;116(2):223-231.
  15. Le Roy, R., Grosshans, E., and Foussereau, J. [Investigation of contact allergies in 100 cases of ulcus cruris (author's transl)]. Derm.Beruf.Umwelt. 1981;29(6):168-170.
  16. Lorenzi, S., Placucci, F., Vincenzi, C., Bardazzi, F., and Tosti, A. Allergic contact dermatitis due to thymol. Contact Dermatitis 1995;33(6):439-440. PubMed
  17. Bahadoran P, Rokni FK, Fahami F. Investigating the therapeutic effect of vaginal cream containing garlic and thyme compared to clotrimazole cream for the treatment of mycotic vaginitis. Iran J Nurs Midwifery Res 2010;15(Suppl 1):343-9.
  18. Erol S, Aydin B, Dilli D, Okumus N, Zenciroglu A, Gündüz M. An interesting newborn case of fructose 1-6 diphosphatase deficiency triggered after thyme juice ingestion. Clin Lab. 2014;60(1):151-3. PubMed

See these in context on the Thyme monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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