No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

ThyroTwin Ingredients & Drug Interactions

by Giant Sports

Capsule Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

ThyroTwin is a dietary supplement by Giant Sports with 2 active ingredients. Its ingredients are commonly taken for weight loss and fat burning, boosting metabolism, bodybuilding and cutting.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of ThyroTwin by Giant Sports

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

ThyroTwin contains 2 active ingredients, both diiodothyronine compounds: 3,5-Diiiodo-L-Thyronine and 3,3'-Diiodo-L-Thyronine. These are thyroid-active compounds designed to influence thyroid function and metabolism.

The product also contains inactive ingredients — gelatin, magnesium stearate, and rice flour — which serve as the capsule material and flow agents.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Diiodothyronine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Fat loss and metabolic acceleration.
  • We looked for evidence on: Obesity, Weight management, Metabolic rate, Body composition.
  • The closest evidence on file: Diiodothyronine is rated "Insufficient Reliable Evidence To Rate" for Obesity (Natural Medicines).

The evidence for both ingredients in ThyroTwin is insufficient to rate. We don't have reliable data showing whether they work for diabetes, cholesterol levels, muscle strength, or weight management.

If you're considering this product for one of those purposes, the science backing these claims isn't established in our records.

The evidence, ingredient by ingredient Diiodothyronine

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both ingredients in this product are thyroid-active compounds with limited human safety data. The facts note possible effects on the heart and thyroid function, so caution is warranted — especially if you have a thyroid condition or heart concern.

During pregnancy, these compounds should be avoided; thyroid-active substances can affect both mother and baby, and safety is unknown. The same goes for breastfeeding — there isn't enough data to know whether these ingredients pass into breast milk or what effect they'd have on an infant.

Talk with your doctor or pharmacist if you're pregnant, planning pregnancy, or breastfeeding.

Side effects, ingredient by ingredient Diiodothyronine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That said, because ThyroTwin contains thyroid-active compounds, talk with your doctor or pharmacist before taking it alongside any thyroid medication, heart medication, or drug that's affected by thyroid hormone levels — they can confirm it's safe to combine in your specific situation.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and some safety-information gaps remain.

ThyroTwin is a thyroid-active supplement with two diiodothyronine ingredients, but the evidence that either works for its claimed purposes is insufficient. Because these compounds affect thyroid function and the safety data is limited, this is one to clear with your own doctor or pharmacist before taking — especially if you have a thyroid condition, take thyroid medication, or have heart concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 10, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about ThyroTwin, straight from the product label.

Brand Giant Sports
Barcode (UPC) 0640052143357
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Oct 10, 2014
DSLD ID 37844
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for ThyroTwin by Giant Sports, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
90
UPC/BARCODE
0640052143357
IngredientAmount% DV
3,5-Diiiodo-L-Thyronine175 mcg--
3,3'-Diiodo-L-Thyronine25 mcg--

Other ingredients: Gelatin, Magnesium Stearate, Rice Flour

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

Store in a cool, dry place between 55 and 85 degrees Fahrenheit. Keep out of direct sunlight.

Seals/Symbols

GIANT SPORTS

General Statements

Fat Loss Modulator & Metabolic Accelerant

- Helps Maximize Daily Caloric Burn Even When You Are At Rest* - Helps Increase Energy Production Via Thyroidal Enzymes* - Promotes Razor-Sharp Cuts And A Lean, Athletic Physique*

Consult with your physician prior to use of this product.

FDA Statement of Identity

Dietary Supplement

Precautions

Warnings: This dietary supplement is intended to be used in healthy adults 18+ years of age.

Do not use this product is you are nursing, pregnant, may be pregnant or are trying to become pregnant.

Do not use this product if you have been diagnosed with infertility, hypothyroidism, hyperthyroidism, have thyroid disease of any sort or take medications for any thyroid disorder.

Do not use this product if you have been diagnosed with infertility, hypothyroidism, hyperthyroidism, have thyroid disease of any sort or take medications for any thyroid disorder.

Do not use this product if you have high blood pressure or have been diagnosed with hypertension. Consult with your physician prior to using this product if you have any psychiatric or neurological condition, any heart or cardiovascular condition, have been diagnosed with high cholesterol or dyslipidemia or have been diagnosed with kidney or liver disease. Discontinue immediately and seek immediate medical assistance if you experience dizziness, severe headache, or shortness of breath. Discontinue the use of this product 14 days prior to any surgery. Individual responses to dietary supplement may vary considerably.

Under no circumstances should more than 2 capsules be consumed in a 24 hour period. This product should be used in conjunction with a proper diet and exercise program. This product may contain ingredients banned by certain sports or professional organizations.

User assumes all liabilities, risks and consequences related to performance enhancing testing and use of this product.

Due to the exceptional potency of this product do not exceed 2 capsules per day under any circumstances. Do not use this product for more than 6 weeks continuously without a 4 week break in use.

ALLERGEN WARNING: Produced in a facility that contains milk, soy, wheat, egg, and nut ingredients.

KEEP OUT OF REACH OF CHILDREN.

Suggested/Recommended/Usage/Directions

Individual responses to dietary supplement may vary considerably. For this reason, some consumers may only need to use 1 capsule per day while others may need to consume 2 capsules per day to achieve desired results. Under no circumstances should more than 2 capsules be consumed in a 24 hour period. This product should be used in conjunction with a proper diet and exercise program.

DIRECTIONS: As a dietary supplement, start by orally ingesting 1 capsule once per day in the morning with 12-16 ounces of water on an empty stomach. If after 7 days the desired effect is not reached, you may increase dosage to 2 capsules once per day in the morning with 12-16 ounces of water on an empty stomach. Due to the exceptional potency of this product do not exceed 2 capsules per day under any circumstances. Do not use this product for more than 6 weeks continuously without a 4 week break in use.

Formula

This product may contain ingredients banned by certain sports or professional organizations.

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat,cure, or prevent any disease.

General

REV# 090513-90TT

See for yourself

ThyroTwin by Giant Sports label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in ThyroTwin by Giant Sports

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

3,5-Diiiodo-L-Thyronine

No known
interactions
175 mcg per serving

Diiodothyronine (T2) is a thyroid hormone metabolite sold as a fat-loss and metabolism supplement, mostly in the bodybuilding world. Human evidence fo...

3,5-Diiiodo-L-Thyronine monograph & interactions

3,3'-Diiodo-L-Thyronine

No known
interactions
25 mcg per serving

Diiodothyronine (T2) is a thyroid hormone metabolite sold as a fat-loss and metabolism supplement, mostly in the bodybuilding world. Human evidence fo...

3,3'-Diiodo-L-Thyronine monograph & interactions

Other (inactive) ingredients: Gelatin, Magnesium Stearate, Rice Flour. These complete the product’s ingredient list but are not active constituents.

Interaction report

ThyroTwin by Giant Sports Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in ThyroTwin. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for ThyroTwin, from the product label.

Giant Sports

See all Giant Sports products
Name
GIANT SPORTS PRODUCTS, LLC
Street Address
990 Cedar Bridge Avenue, Suite B7-280
City
Brick
State
NJ
ZipCode
08723
Pharmacist Counseling Corner

ThyroTwin by Giant Sports: Common Questions

Does ThyroTwin by Giant Sports interact with any medications?
We do not currently list a known interaction for the mapped ingredients in ThyroTwin. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
ThyroTwin contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take ThyroTwin if I'm pregnant or breastfeeding?
No — both ingredients should be avoided during pregnancy and while breastfeeding. Thyroid-active compounds can affect the mother and baby, and safety in pregnancy and lactation is unknown. Talk with your doctor or pharmacist before taking this product if you're pregnant, planning pregnancy, or nursing.
Does ThyroTwin actually help with weight loss or metabolism?
The evidence for either ingredient in ThyroTwin isn't strong enough to say. Both compounds show insufficient reliable evidence to rate for obesity, muscle strength, cholesterol, or diabetes. We don't have solid science backing those uses.
Are there any side effects listed for ThyroTwin?
No adverse effects are documented in our data for either ingredient. However, because both are thyroid-active compounds with limited human safety data, the facts note caution due to possible effects on the heart and thyroid. Any unusual symptoms warrant a call to your doctor or pharmacist.
Should I be worried about taking this with thyroid medication?
These ingredients are thyroid-active, so it's smart to check before combining them with any thyroid drug or medication affected by thyroid function. Your doctor or pharmacist can tell you whether it's safe together and whether you need monitoring.
What exactly are 3,5-Diiiodo-L-Thyronine and 3,3'-Diiodo-L-Thyronine?
Both are diiodothyronine compounds — thyroid-active substances meant to influence thyroid function. They're related to thyroid hormones but are distinct compounds. Limited human safety data is available for either one.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if ThyroTwin is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

ThyroTwin label
Sources

Sources & How We Checked

ThyroTwin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Diiodothyronine 3 references
  1. Thyroid Hormone — MedlinePlus (U.S. National Library of Medicine) Source
  2. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
  3. Using Dietary Supplements Wisely — NIH NCCIH Source

See these in context on the Diiodothyronine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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