Triphala 1500 mg Ingredients & Drug Interactions
by Solaray
What is this page for?
First and foremost: checking Triphala 1500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Triphala 1500 mg is a dietary supplement by Solaray with 3 active ingredients. Its ingredients are commonly taken for heart health and circulation, digestive problems (constipation, diarrhea), cholesterol support.Based on those ingredients, 933 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Belleric Myrobalan fruit extract, Amla Fruit Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Triphala 1500 mg by Solaray
Ask about any prescription or over-the-counter medication and we check it for interactions with Triphala 1500 mg by Solaray — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Triphala 1500 mg by Solaray
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Solaray Triphala contains three active ingredients, all fruit extracts from traditional Ayurvedic herbs: amla fruit extract (Indian gooseberry), belleric myrobalan fruit extract, and chebulic myrobalan fruit extract. The product also includes cellulose and rice extract blend as inactive ingredients (fillers and capsule materials).
Each capsule delivers 1,500 mg total.
Does it work?
Moderate evidence
In the data we hold, amla fruit extract (one of the three active ingredients) is rated possibly effective for gastroesophageal reflux disease (GERD) and dyslipidemia (elevated blood lipids). For high cholesterol and male-pattern hair loss, the evidence is insufficient to rate it either way.
We don't have effectiveness ratings on file for the other two ingredients in this blend.
How safe is it?
Well-documented data
Amla fruit extract is generally well tolerated as a food, but supplement safety at therapeutic doses is less studied. There isn't enough safety data to recommend it during pregnancy or breastfeeding — talk with your doctor or pharmacist about whether it's right for you if you're pregnant or nursing.
In clinical trials, a small number of people reported stomach discomfort or indigestion, and individual cases of fatigue and muscle pain were noted.
Meds to double-check
Moderate interaction found
Before taking this product, check with your pharmacist if you use blood thinners (anticoagulants) or antiplatelet drugs — amla may increase your bleeding risk (Moderate). Also double-check if you take diabetes medications, since amla can lower your blood sugar and may require dose adjustments (Moderate).
Ask your pharmacist to run your specific medications through the interaction checker on this page.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Triphala might appeal to you if you're interested in traditional Ayurvedic support for digestion or cholesterol, but it's not for everyone. If you take blood thinners, antiplatelet drugs like clopidogrel, aspirin, or diabetes medications, you need to check with your pharmacist or doctor first — amla can increase bleeding risk and lower blood sugar.
Pregnant or breastfeeding? Talk to your pharmacist before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Triphala 1500 mg, straight from the product label.
| Brand | Solaray |
|---|---|
| Barcode (UPC) | 076280399172 |
| Net contents | 90 VegCap(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2025 |
| DSLD ID | 339130 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Triphala 1500 mg by Solaray, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Belleric Myrobalan fruit extract | 500 mg | -- |
| Chebulic Myrobalan fruit extract | 500 mg | -- |
| Amla Fruit Extract | 500 mg | -- |
Other ingredients: Cellulose, Rice extract Blend
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Solaray Est. 1973 A brighter way 1973
General Statements
Vital extracts
Since 1973, we've scoured the globe for the highest quality ingredients, connecting you with the most efficacious supplements that help you live brighter & embrace the moments that matter most.
100% PCR bottles
Formula
Triphala 1500 mg 42% tannins Per serving
Discussion: Triphala, one of the most widely used herbal blends in ayurveda, was valued by the ancient Hindus as a "good manager of the house" that helps support overall health and immunity.
Formulation
Herbal support
Vegan
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Lab Verified Vegan
Precautions
Warning: Do not use if safety seal is broken or missing. Keep your licensed health care practitioner informed when using this product. Contraindicated in acute cough, acute diarrhea, and early stage of dysentery.
Keep out of reach of children.
Directions: Use only as directed.
Suggested/Recommended/Usage/Directions
Directions: Use only as directed. Take 3 VegCaps daily with a meal or glass of water.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Triphala 1500 mg by Solaray label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Triphala 1500 mg by Solaray
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size3 VegCap(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Belleric Myrobalan fruit extract
Interacts with933 drugs
Terminalia is a group of traditional Ayurvedic tree species (most notably Terminalia arjuna) used for heart, digestive, and general wellness purposes....
Belleric Myrobalan fruit extract monograph & interactionsChebulic Myrobalan fruit extract
Amla Fruit Extract
Interacts with208 drugs
Indian gooseberry (amla) is a vitamin C-rich fruit used in Ayurvedic medicine for many purposes, from antioxidant support to cholesterol and digestion...
Amla Fruit Extract monograph & interactionsOther (inactive) ingredients: Cellulose, Rice extract Blend. These complete the product’s ingredient list but are not active constituents.
Triphala 1500 mg by Solaray Drug Interactions
HelloPharmacist Interaction Report
Solaray Triphala 1500 mg contains amla fruit extract (Indian gooseberry), which has documented interactions with several medication types.
The most serious concern is with blood thinners and antiplatelet drugs — amla may increase bleeding risk. Research shows it reduces how well platelets clump together and lengthens bleeding time, which matters if you take warfarin, clopidogrel (Plavix), or aspirin.
Read the full breakdown — every affected drug type, severity by severity
Amla also interacts with diabetes medications (Moderate severity). It can lower your blood sugar on its own, so combining it with diabetes drugs might push your glucose too low — you'd need your doctor to adjust your medication dose.
We couldn't check the other two ingredients in this product, belleric myrobalan and chebulic myrobalan, because we don't hold interaction data for them. Altogether, these interactions span 207 individual medications.
Before you start Triphala, run your exact medications through the checker on this page.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Triphala 1500 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Triphala 1500 mg interact with 933 drugs. Click any drug to see the details.
2 of the 3 ingredients in Triphala 1500 mg interact with drugs. Each result below shows which ingredient is responsible. Belleric Myrobalan fruit extract Amla Fruit Extract
Acetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, ChlorzoxazoneAcetazone Forte, Extra Strength Tylenol Aches & Strains, Parafon Forte
How Acetaminophen, Chlorzoxazone interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractChlorzoxazone (parafon Forte, Paraflex) Moderate
Interaction Summary
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from chlorzoxazone.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Chlorzoxazone interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractChlorzoxazone (parafon Forte, Paraflex), Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from chlorzoxazone.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, DextromethorphanTylenol Cough Ex Strength
How Acetaminophen, Dextromethorphan interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Dextromethorphan interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylephrineConar-A
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylpropanolamineAnatuss
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PseudoephedrineRobitussin Cold, Severe Cold, Suphedrine Cold/Cough
How Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Phenylpropanolamine, PyrilamineTheracaps
How Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interactionAcetaminophen, Dextromethorphan, PseudoephedrineAlka-Seltzer PLUS Flu Liquid Gels, Non Aspirin Cold Caps, Tylenol Cold, Tylenol Flu Daytime Ex Strength, Tylenol Flu Ex Strength
How Acetaminophen, Dextromethorphan, Pseudoephedrine interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, HydrocodoneAnexsia, Anodynos DHC, Azdone, Co-Gesic, Doucet, Lorcet +9 more
How Acetaminophen, Hydrocodone interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Hydrocodone interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Triphala 1500 mg — through 2 ingredients. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 2c9 (cyp2c9) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Ibuprofen interactionAmla Fruit ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Indian gooseberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Amla Fruit Extract + Acetaminophen, Ibuprofen interactionAcetaminophen, MeperidineDemerol APAP
How Acetaminophen, Meperidine interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Meperidine interactionAcetaminophen, OxycodonePercocet, Roxicet, Tylox, Xartemis XR
How Acetaminophen, Oxycodone interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Oxycodone interactionAcetaminophen, Phenylephrine, ChlorpheniramineSuper Cold Tabs
How Acetaminophen, Phenylephrine, Chlorpheniramine interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAcetaminophen, PropoxypheneDarvocet-N 100, Darvocet-N 50, E-Lor, Wygesic
How Acetaminophen, Propoxyphene interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Belleric Myrobalan Fruit Extract + Acetaminophen, Propoxyphene interactionAcetohexamideDymelor
How Acetohexamide interacts with Triphala 1500 mg — through 2 ingredients. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Read the full Belleric Myrobalan Fruit Extract + Acetohexamide interactionAmla Fruit ExtractAntidiabetes Drugs Moderate
Interaction Summary
Taking Indian gooseberry with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Amla Fruit Extract + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Triphala 1500 mg — through 2 ingredients. Tap an ingredient for the detail:
Amla Fruit ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, Indian gooseberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Amla Fruit Extract + Acetylsalicylic Acid interactionBelleric Myrobalan Fruit ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Belleric Myrobalan Fruit Extract + Acetylsalicylic Acid interactionAdagrasibKrazati
How Adagrasib interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Belleric Myrobalan Fruit Extract + Adagrasib interactionAerosphere Budesonide, Formoterol Fumarate, GlycopyrrolateBreztri
How Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 2c9 (cyp2c9) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
Read the full Belleric Myrobalan Fruit Extract + Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interactionAgomelatineValdoxan
How Agomelatine interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
Read the full Belleric Myrobalan Fruit Extract + Agomelatine interactionAlbiglutideTanzeum
How Albiglutide interacts with Triphala 1500 mg — through 2 ingredients. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Read the full Belleric Myrobalan Fruit Extract + Albiglutide interactionAmla Fruit ExtractAntidiabetes Drugs Moderate
Interaction Summary
Taking Indian gooseberry with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Amla Fruit Extract + Albiglutide interactionAlfentanilAlfenta
How Alfentanil interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Belleric Myrobalan Fruit Extract + Alfentanil interactionAlfuzosinUroxatral
How Alfuzosin interacts with Triphala 1500 mg — through 1 ingredient. Tap an ingredient for the detail:
Belleric Myrobalan Fruit ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Belleric Myrobalan Fruit Extract + Alfuzosin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Triphala 1500 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Belleric Myrobalan fruit extract
Anticoagulant/Antiplatelet Drugs
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
In vitro, Terminalia arjuna bark extract inhibits platelet aggregation, decreases platelet activation, and shows antithrombotic properties.
Antidiabetes Drugs
Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Animal and in vitro research shows that Terminalia bellirica and Terminalia chebula fruit and seed extract have hypoglycemic effects.
Chlorzoxazone (Parafon Forte, Paraflex)
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from chlorzoxazone.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of chlorzoxazone increases blood levels of chlorzoxazone and decreases chlorzoxazone clearance. It is speculated that Terminalia chebula reduces the metabolism of chlorzoxazone by inhibiting cytochrome P450 2E1.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2C9 enzymes and reduces CYP2C9 substrate metabolism.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2D6 enzymes and reduces CYP2D6 substrate metabolism.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP3A4 enzymes and reduces CYP3A4 substrate metabolism.
Omeprazole (Prilosec)
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from omeprazole.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of omeprazole increases blood levels of omeprazole and decreases omeprazole clearance. It is speculated that Terminalia chebula reduces the metabolism of omeprazole by inhibiting cytochrome P450 2C19.
Amla Fruit Extract
Anticoagulant/Antiplatelet Drugs
Theoretically, Indian gooseberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking Indian gooseberry 500 mg along with clopidogrel 75 mg or ecosprin 75 mg, as a single dose or for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg or ecosprin 75 mg alone. Until more is known, use caution when taking Indian gooseberry in combination with anticoagulant/antiplatelet drugs.
Antidiabetes Drugs
Taking Indian gooseberry with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking Indian gooseberry fruit or fruit extract alone or in conjunction with antidiabetes medications can lower blood glucose levels. Dose adjustments to diabetes medications might be necessary.
Aspirin
Theoretically, Indian gooseberry may increase the risk of bleeding if used with aspirin; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with ecosprin 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus ecosprin 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with ecosprin 75 mg alone.
Clopidogrel (Plavix)
Theoretically, Indian gooseberry may increase the risk of bleeding if used with clopidogrel; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with clopidogrel 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus clopidogrel 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg alone.
Brand information
Manufacturer and brand details for Triphala 1500 mg, from the product label.
Triphala 1500 mg by Solaray: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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The Full Monographs Behind Triphala 1500 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Terminalia
Interacts with 933 drugsTerminalia is a group of traditional Ayurvedic tree species (most notably Terminalia arjuna) used for heart, digestive, and general wellness purposes. Some small studies suggest possible ben...
Read the full Terminalia monograph → Herb & supplement monographIndian Gooseberry
Interacts with 208 drugsIndian gooseberry (amla) is a vitamin C-rich fruit used in Ayurvedic medicine for many purposes, from antioxidant support to cholesterol and digestion. Early research is promising for some u...
Read the full Indian Gooseberry monograph →Sources & How We Checked
Triphala 1500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 15 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Terminalia 9 references
- Sabu, M. C. and Kuttan, R. Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol. 2002;81(2):155-160. PubMed
- Rao, N. K. and Nammi, S. Antidiabetic and renoprotective effects of the chloroform extract of Terminalia chebula Retz. seeds in streptozotocin-induced diabetic rats. BMC.Complement Altern.Med 2006;6:17. PubMed
- Murali, Y. K., Anand, P., Tandon, V., Singh, R., Chandra, R., and Murthy, P. S. Long-term effects of Terminalia chebula Retz. on hyperglycemia and associated hyperlipidemia, tissue glycogen content and in vitro release of insulin in streptozotocin induced
- Senthilkumar, G. P. and Subramanian, S. Evaluation of antioxidant potential of Terminalia chebula fruits studies in streptozotocin-induced diabetic rats. Pharmaceutical Biology (Netherlands) 2007;45:511-518.
- Malik N, Dhawan V, Bahl A, Kaul D. Inihbitory effects of Terminalia arjuna on platelet activation in vitro in healthy subjects and patients with coronary artery disease. Platelets. 2009;20(3):183-1190.
- Varghese A, Savai J, Pandita N, Gaud RS. In vitro modulatory effects of Terminalia arjuna, arjunic acid, arjunetin, and arjungenin on CYP3A4, CYP2D6, and CYP2C9 enzyme activity in human liver microsomes. Toxicology Reports. 2015(2):806-16. PubMed
- Wu G, Dong Z, Dong J, et al. Effects of mongolian medicine Terminalia chebula Retz. on 6 CYP450 enzymes in rats. Int J Clin Exp Pathol 2020;13(12):3128-3138.
- Das A, Naveen J, Sreerama YN, Gnanesh Kumar BS, Baskaran V. Low-glycemic foods with wheat, barley and herbs (Terminalia chebula, Terminalia bellerica and Emblica officinalis) inhibit a-amylase, a-glucosidase and DPP-IV activity in high fat and low dose st
- Eltimamy M, Elshamarka M, Aboelsaad M, Sayed M, Moawad H. Effects of alcoholic extract of Terminalia Chebula dried fruit on blood biochemical profile in diabetic rats. J Diabetes Metab Disord 2022;21(1):159-170. PubMed
Indian Gooseberry 6 references
- Sabu, M. C. and Kuttan, R. Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol. 2002;81(2):155-160. PubMed
- Fatima N, Pingali U, Muralidhar N. Study of pharmacodynamic interaction of Phyllanthus emblica extract with clopidogrel and ecosprin in patients with type II diabetes mellitus. Phytomedicine. 2014;21(5):579-85. PubMed
- Shanmugarajan D, Girish C, Harivenkatesh N, Chanaveerappa B, Prasanna Lakshmi NC. Antihypertensive and pleiotropic effects of Phyllanthus emblica extract as an add-on therapy in patients with essential hypertension-A randomized double-blind placebo-contro
- Akhtar MS, Ramzan A, Ali A, Ahmad M. Effect of amla fruit (Emblica officinalis Gaertn.) on blood glucose and lipid profile of normal subjects and type 2 diabetic patients. Int J Food Sci Nutr. 2011;62(6):609-16.
- Usharani P, Fatima N, Muralidhar N. Effects of Phyllanthus emblica extract on endothelial dysfunction and biomarkers of oxidative stress in patients with type 2 diabetes mellitus: a randomized, double-blind, controlled study. Diabetes Metab Syndr Obes. 20 PubMed
- Majeed M, Mundkur L, Paulose S, Nagabhushanam K. Novel Emblica officinalis extract containing ß-glucogallin vs. metformin: a randomized, open-label, comparative efficacy study in newly diagnosed type 2 diabetes mellitus patients with dyslipidemia. Food Fu
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC