No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 3 of 15 ingredients. Check your meds →
Dietary supplement

Valenzym Digestive Enzyme Ingredients & Drug Interactions

by Carotec

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Valenzym Digestive Enzyme is a dietary supplement by Carotec with 15 active ingredients. Its ingredients are commonly taken for lactose intolerance, gas and bloating after dairy, diarrhea from dairy foods.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Valenzym Digestive Enzyme by Carotec

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 15 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (250 mg) without saying how much of each component you get.

Valenzym contains 15 ingredients total, most of them digestive enzymes. The active components include lactase (which breaks down milk sugar), phytase, proteolytic enzymes in four forms (Protease 3.0, Protease 6.0, Neutral Protease, and Protease A 4.5), and several others designed to help your body digest different types of food.

The inactive ingredients are mostly common binders and fillers like calcium carbonate, dextrose, and silicon dioxide.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Digestive enzyme support.
  • We looked for evidence on: Lactose intolerance, Digestive bloating, Gas and bloating, Plant-based food digestion.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).

Lactase is effective for lactose intolerance — if you have trouble digesting milk sugar, this enzyme can help break it down. The evidence for other uses with lactase (like colic or prematurity) isn't established.

For phytase and the proteolytic enzymes in this blend, we don't have effectiveness ratings in our data, so we can't tell you whether they work for their intended purposes based on what we hold.

The evidence, ingredient by ingredient Lactase Phytase Proteolytic Enzymes (proteases)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactase is generally well tolerated when used as directed. The proteolytic enzymes are also generally well tolerated in most adults, though they may cause digestive upset or allergic reactions in some people.

Rare cases of allergic reactions to lactase and protease have been reported, mainly in workers with heavy occupational exposure to the powdered forms. Phytase carries immunologic concerns from occupational airborne exposure, though data on oral supplements are limited.

During pregnancy, lactase is rated likely safe, but phytase safety data are incomplete — talk with your doctor. The proteolytic enzymes (proteases) are best avoided in pregnancy unless your doctor prescribes them.

For breastfeeding, lactase safety is not well studied; phytase and the proteases have limited data, so check with your doctor or pharmacist first before regular use.

Side effects, ingredient by ingredient Lactase Phytase Proteolytic Enzymes (proteases)

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 3 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Still, if you take any medications regularly, it's worth a quick check below to be sure.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This is a digestive enzyme blend that works well for lactose intolerance. If you have trouble digesting milk products or want broad enzyme support with meals, it's worth a try.

Check with your pharmacist if you're pregnant, planning to breastfeed, or have a history of allergies to enzyme products — and run your medications through our tool below.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 15 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Valenzym Digestive Enzyme, straight from the product label.

Brand Carotec
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Feb 21, 2023
DSLD ID 282143
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Valenzym Digestive Enzyme by Carotec, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
60
IngredientAmount% DV
Proprietary Blend250 mg--
Lactase0 NP--
Beta-Glucanase0 NP--
Cellulase0 NP--
Phytase0 NP--
Hemicellulase0 NP--
Alpha-Galactosidase0 NP--
Amylase0 NP--
Maltase0 NP--
Glucoamylase0 NP--
Invertase0 NP--
Protease 3.00 NP--
Protease 6.00 NP--
Neutral Protease0 NP--
Protease A 4.50 NP--
Yeast Lipase0 NP--

Other ingredients: Calcium Carbonate, Calcium Gluconate, Cassava Dextrin, Dextrose, Dicalcium Phosphate, D-Mannitol, Maltodextrin, Potassium Sorbate, Potato Dextrin, Silicon Dioxide, Sodium Benzoate, Sodium Chloride, Tapioca Dextrin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take one (1) to two (2) capsules during or near end of meal. Advanced use: Adults may gradually increase to three (3) capsules during or near end of meal.

Storage

Store in a cool, dry place after opening.

Precautions

Warning: Keep out reach of children.

If you are pregnant, nursing or taking medication, consult your doctor before use.

Discontinue use and consult your doctor if adverse reactions occur.

Brand IP Statement(s)

Valenzym is a registered trademark of Carotec, Inc.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

See for yourself

Valenzym Digestive Enzyme by Carotec label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Valenzym Digestive Enzyme by Carotec

These are the 15 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

250 mg per serving

Other (inactive) ingredients: Calcium Carbonate, Calcium Gluconate, Cassava Dextrin, Dextrose, Dicalcium Phosphate, D-Mannitol, Maltodextrin, Potassium Sorbate, Potato Dextrin, Silicon Dioxide, Sodium Benzoate, Sodium Chloride, Tapioca Dextrin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Valenzym Digestive Enzyme by Carotec Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Valenzym Digestive Enzyme. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Valenzym Digestive Enzyme, from the product label.

Carotec

See all Carotec products
Name
Carotec, Inc.
Street Address
P.O. Box 9919
City
Naples
State
FL
ZipCode
34101
Phone Number
1-800-522-4279
Web Address
www.carotec.com
Pharmacist Counseling Corner

Valenzym Digestive Enzyme by Carotec: Common Questions

Does Valenzym Digestive Enzyme by Carotec interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Valenzym Digestive Enzyme. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Valenzym Digestive Enzyme contains 15 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this actually help with lactose intolerance?
Yes — lactase is effective for lactose intolerance. If you have trouble digesting milk sugar, this enzyme breaks it down and can help reduce symptoms.
Can I take this while pregnant?
Lactase is rated likely safe in pregnancy. The proteolytic enzymes are best avoided unless your doctor prescribes them. For the other ingredients, safety data aren't on file, so talk with your doctor or pharmacist about whether it's right for you.
What about breastfeeding?
Lactase safety during breastfeeding hasn't been well studied. The proteolytic enzymes have little safety data and are not recommended without medical advice. For the remaining ingredients, we don't have breastfeeding information, so check with your doctor first.
Can this cause side effects?
The enzymes are generally well tolerated. Some people may experience digestive upset or allergic reactions, especially if they have a sensitivity to enzymes. Rare allergic reactions to lactase and protease have been reported, mainly from heavy occupational exposure.
What are all these different proteases for?
The product contains four protease forms — they're all versions of proteolytic enzymes designed to break down proteins in your food to aid digestion. Different forms may work at different pH levels in your gut.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Valenzym Digestive Enzyme is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Valenzym Digestive Enzyme label
Sources

Sources & How We Checked

Valenzym Digestive Enzyme's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Phytase 7 references
  1. Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
  2. Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
  3. van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
  4. Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
  5. Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
  6. Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
  7. Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.

See these in context on the Phytase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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