No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Vegetable Glycerin Ingredients & Drug Interactions

by Hawaii Pharm

Vegetable Glycerin label
See full label image
Liquid Category: Non-nutrient/non-botanical
No known interaction
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Vegetable Glycerin against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Vegetable Glycerin is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for constipation (laxative), dry skin (moisturizer), dry, irritated eyes.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

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HelloPharmacist Scorecard of Vegetable Glycerin by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: glycerin (also called glycerol), a naturally derived compound commonly used in oral and topical forms. The product has no inactive ingredients listed.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Glycerol's overall clinical evidence instead.

Strong

Strong clinical evidence supports Glycerol for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Constipation — rated "Likely Effective" (Natural Medicines).
  • On file: Athletic performance — rated "Possibly Effective" (Natural Medicines).
  • On file: Ichthyosis — rated "Possibly Effective" (Natural Medicines).

Glycerin has the strongest evidence for constipation, where it's considered likely effective. For ichthyosis (dry, scaly skin) and athletic performance, the evidence is mixed — marked possibly effective.

It's been studied for meningitis, prematurity, and stroke, but those uses are likely ineffective or worse according to the data we hold.

The evidence, ingredient by ingredient Glycerol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glycerin is generally well tolerated at normal amounts. Taken orally in large doses, it may cause bloating, diarrhea, nausea, vomiting, dizziness, and headache, as well as dehydration concerns — so talk to your doctor before using medicinal amounts.

Topical use can occasionally cause burning, irritation, or itching. There isn't much specific safety data on larger medicinal doses, so check with your doctor before going beyond normal food and topical amounts.

Side effects, ingredient by ingredient Glycerol

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for glycerin in the data we hold. If you're taking any medications, check with your pharmacist or use the tool on this page to be certain.

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

Vegetable glycerin is a reasonable choice if you're looking at it for constipation or dry skin, where there's some solid evidence behind it. If you're thinking of using medicinal doses, talk to your doctor first — large amounts can upset your stomach and pull fluid into your gut.

There are no documented interactions with medications in our data, but run it by your pharmacist if you're on anything regularly.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vegetable Glycerin, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 650905474064
Net contents 16 fl. Oz.; 473 mL
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 269069
Product type Non-nutrient/non-botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Kosher, Halal
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vegetable Glycerin by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
10 mL
Maximum serving Sizes:
10 mL
Servings per container
47
UPC/BARCODE
650905474064
IngredientAmount% DV
Glycerin1260 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Uses: Used in food products, vapes, sanitizers, cosmetics, tinctures, extracts, lotions, as emulsifiers, stage fog, thickener, solvent, emollient, plasticizer, humectant, sweetener, lubricant, anti-freeze, drug excipient. Used as intermediate for making glycerol derivatives.

Perfect for internal and external use

Precautions

Warning: Keep out of reach of children.

Do not use if you are allergic to glycerin.

Formulation

Pure refined vegetable glycerine USP food grade

GMO free

USP, food grade.

Formula

Kosher and halal certified.

Kosher and halal certified.

Seals/Symbols

Packaged in an FDA registered facility

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Vegetable Glycerin by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Vegetable Glycerin label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Vegetable Glycerin by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size10 mL Dosage formLiquid Servings per container47 Amounts shown are per serving.

Glycerin

No known
interactions
1260 mg per serving

Glycerol (glycerin) is a sweet, syrupy compound made naturally in the body and widely used in foods, skin products, and medicines. It is well establis...

Glycerin monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vegetable Glycerin by Hawaii Pharm Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Vegetable Glycerin. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Vegetable Glycerin, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
Street Address
510 Sumner St 613
City
Honolulu
State
HI
ZipCode
96817
Phone Number
1-808-385-6076
Web Address
www.hawaiipharm.com
Pharmacist Counseling Corner

Vegetable Glycerin by Hawaii Pharm: Common Questions

Does Vegetable Glycerin by Hawaii Pharm interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Vegetable Glycerin. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Vegetable Glycerin contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will glycerin help with constipation?
Yes — glycerin is considered likely effective for constipation. It works partly by drawing fluid into the bowel. Just be aware that large doses can cause bloating, diarrhea, and nausea, so start small and talk to your doctor if you want to use it regularly in higher amounts.
Can I use this on my skin?
Glycerin is generally well tolerated on the skin, and it's possibly effective for ichthyosis (dry, scaly skin). A small number of people may experience burning, irritation, or itching, so test it on a small area first.
What side effects might I notice if I take it by mouth?
Common ones are bloating, diarrhea, nausea, vomiting, dizziness, and headache — especially at larger doses. These tend to be mild, but if they bother you, lower the dose or talk to your doctor.
Is there safety data on this product during pregnancy or breastfeeding?
We don't have specific safety data on file for glycerin in pregnancy and lactation. Talk to your doctor or pharmacist about whether it's right for you if you're pregnant or nursing — they can give you personalized advice.
Can this help me with athletic performance?
Glycerin is marked possibly effective for athletic performance in the data we hold, but the evidence is mixed. Talk to your doctor or sports medicine specialist if you're thinking about using it for that purpose.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vegetable Glycerin is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vegetable Glycerin label
Go deeper

The Full Monographs Behind Vegetable Glycerin’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glycerol

Glycerol (glycerin) is a sweet, syrupy compound made naturally in the body and widely used in foods, skin products, and medicines. It is well established as a laxative and a skin and eye moi...

Read the full Glycerol monograph →
Sources

Sources & How We Checked

Vegetable Glycerin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glycerol 8 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Wagner DR. Hyperhydrating with glycerol: implications for athletic performance. J Am Diet Assoc 1999;99:207-12. PubMed
  3. Yu YL, Kumana CR, Lauder IJ, et al. Treatment of acute cortical infarct with intravenous glycerol. A double-blind, placebo-controlled randomized trial. Stroke 1993;24:1119-24. PubMed
  4. Frei A, Cottier C, Wunderlich P, Ludin E. Glycerol and dextran combined in the therapy of acute stroke. A placebo-controlled, double-blind trial with a planned interim analysis. Stroke 1987;18:373-9. PubMed
  5. Balaskas E, Szepietowski JC, Bessis D, Ioannides D, Ponticelli C, Ghienne C, Taberly A, Dupuy P. Randomized, double-blind study with glycerol and paraffin in uremic xerosis. Clin J Am Soc Nephrol. 2011 Apr;6(4):748-52. PubMed
  6. Blanchet-Bardon C, Tadini G, Machado Matos M, Delarue A. Association of glycerol and paraffin in the treatment of ichthyosis in children: an international, multicentric, randomized, controlled, double-blind study. J Eur Acad Dermatol Venereol. 2012 Aug;26 PubMed
  7. Kajita N, Kanamori K, Yamamoto S, Yoshida K. Generalized Urticaria Caused by a Glycerin Enema in an Infant. J Investig Allergol Clin Immunol 2022;32(4):318-319. PubMed
  8. Suzuki R, Fukuyama K, Miyazaki Y, Namiki T. Contact urticaria syndrome and protein contact dermatitis caused by glycerin enema. JAAD Case Reports. 2016;2:108-10. PubMed

See these in context on the Glycerol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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