No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Vegetarian Pancreatin 475 mg Ingredients & Drug Interactions

by Source Naturals

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Vegetarian Pancreatin 475 mg is a dietary supplement by Source Naturals with 4 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Vegetarian Pancreatin 475 mg by Source Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 4 active ingredients.

This product has 4 active ingredients: protease, pancreatin, alpha amylase, and alpha-lipase — all digestive enzymes that work to break down proteins, carbohydrates, and fats in your food. The capsule itself contains cellulose and magnesium stearate as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: digestive enzyme support for protein, starch, and fat breakdown.
  • We looked for evidence on: Dyspepsia, pancreatic insufficiency, indigestion, fat malabsorption.
  • The closest evidence on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia (Natural Medicines).

The evidence for these enzymes is limited. For alpha-lipase (lipase), we have insufficient reliable evidence to rate whether it helps with inflammatory bowel disease (IBD), dyspepsia (indigestion), or prematurity.

No effectiveness ratings are on file for protease in our data.

The evidence, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Protease and alpha-lipase are generally well tolerated by most adults, though some people report digestive upset or allergic reactions. Protease can rarely trigger allergic responses, especially with airborne exposure.

For pregnancy, the safety data on protease advises against use unless prescribed by your doctor. For alpha-lipase in pregnancy, there isn't enough data — talk with your doctor before taking it.

During breastfeeding, neither ingredient has enough safety data; check with your healthcare provider first. Alpha-lipase has not been thoroughly studied for safety overall, and people with serious digestive conditions should use it only under medical guidance.

Side effects, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented for the ingredients we could check. That said, we could not verify interaction data for pancreatin and alpha amylase, so if you take any medications, run them through the search tool on this page to be sure.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

This is a straightforward digestive enzyme supplement with no medication interactions documented. If you have a serious digestive condition or are pregnant or breastfeeding, talk with your doctor or pharmacist before starting it — the safety data is limited in those situations.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vegetarian Pancreatin 475 mg, straight from the product label.

Brand Source Naturals
Barcode (UPC) 021078017110
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2023
DSLD ID 296344
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vegetarian Pancreatin 475 mg by Source Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
021078017110
IngredientAmount% DV
Protease0 NP--
Pancreatin475 mg--
Alpha Amylase0 NP--
Alpha-Lipase0 NP--

Other ingredients: Cellulose, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Formula

Digestive Plant Enzymes in Vegetarian Capsules

Source Naturals Vegetarian Pancreatin is a broad-spectrum plant-based enzyme blend. It includes protease for protein breakdown, amylase or starch breakdown, and lipase for fat breakdown. Unlike pancreatin derived from animal sources, vegetarian pancreatin works at a wide range of pH levels to break down food in the acidic stomach as well as the more neutral intestines. Plus, vegetarian pancreatin can help digest wheat gluten, which may increase stomach and intestinal comfort. Supplementing the body's digestive process with enzymes is of great value in today's fast-paced society.

Suggested/Recommended/Usage/Directions

Suggested use: 1 capsule with water at the beginning of each meal (or open capsule and sprinkle over food). If the meal is very large or usually high in fat or protein, a second capsule can be taken after eating. Do not sprinkle in hot food.

Precautions

Note: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.

Do not use if either tamper-evident seal is broken or missing.

Keep out of the reach of children.

Storage

Store in a cool, dry place.

Formulation

Suitable for vegetarians.

Contains no dairy, egg, gluten, soy or wheat. Contains no sugar, starch, salt, preservatives, or artificial color, flavor or fragrance.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Copyright SOURCE NATURALS, INC.

See for yourself

Vegetarian Pancreatin 475 mg by Source Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Vegetarian Pancreatin 475 mg by Source Naturals

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protease

No known
interactions
0 NP per serving

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...

Protease monograph & interactions

Pancreatin

475 mg per serving

Alpha Amylase

0 NP per serving

Alpha-Lipase

No known
interactions
0 NP per serving

Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy fo...

Alpha-Lipase monograph & interactions

Other (inactive) ingredients: Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vegetarian Pancreatin 475 mg by Source Naturals Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Vegetarian Pancreatin 475 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Vegetarian Pancreatin 475 mg, from the product label.

Source Naturals

Name
Source Naturals, Inc.
Street Address
P. O. Box 2118
City
Santa Cruz
State
CA
ZipCode
95062
Web Address
www.sourcenaturals.com
Pharmacist Counseling Corner

Vegetarian Pancreatin 475 mg by Source Naturals: Common Questions

Does Vegetarian Pancreatin 475 mg by Source Naturals interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Vegetarian Pancreatin 475 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Vegetarian Pancreatin 475 mg contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What do these enzymes actually do?
They break down different parts of your food — protease cuts up proteins, alpha amylase breaks down carbs, and alpha-lipase (lipase) breaks down fats. It's the same job your own digestive system does, just in supplement form.
Can I take this if I'm pregnant?
Protease should be avoided in pregnancy unless your doctor prescribes it. For lipase, there isn't enough safety data, so talk with your doctor before taking it. Your healthcare provider can tell you whether it's okay for your situation.
What if I have a sensitive stomach?
These enzymes can cause digestive upset in some people, and protease can rarely trigger allergic reactions. If you have a serious digestive condition, use it only under medical guidance — check with your doctor or pharmacist first.
Does this actually work for digestion?
The evidence is limited. We don't have reliable data to say whether these enzymes help with indigestion or digestive disorders — it's not established in our data.
What's in the capsule besides the enzymes?
Just cellulose and magnesium stearate — both are standard inactive ingredients that help hold the capsule together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vegetarian Pancreatin 475 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vegetarian Pancreatin 475 mg label
Sources

Sources & How We Checked

Vegetarian Pancreatin 475 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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