No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 4 of 25 ingredients. Check your meds →
Dietary supplement

Vital-Zymes Complete Ingredients & Drug Interactions

by Klaire Labs

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Vital-Zymes Complete is a dietary supplement by Klaire Labs with 25 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Vital-Zymes Complete by Klaire Labs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 25 active ingredients.
  • “Comprehensive Enzyme Blend” is a proprietary blend — the label gives one combined amount (750 mg) without saying how much of each component you get.

Vital-Zymes Complete contains 25 active digestive enzymes designed to break down different components of food. The checked ingredients include Lipase (which breaks down fats), Lactase (which breaks down milk sugar), Phytase (which helps break down plant compounds), and Acid Proteases and Alkaline Proteases (which break down proteins).

The product also contains several other enzyme types — some we could check and some we don't have data for — along with inactive ingredients like cellulose and ascorbyl palmitate (a form of vitamin C).

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Comprehensive enzyme support for digestion.
  • We looked for evidence on: Dyspepsia, Lactose intolerance, Bloating, Gas and indigestion, Fat maldigestion, Plant food intolerance.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

The evidence for most ingredients in this blend isn't well established. Lactase is rated effective for lactose intolerance — if you have trouble digesting milk products, this enzyme can help.

For the other checked ingredients — Lipase, Phytase, Acid Proteases, and Alkaline Proteases — the data we hold shows insufficient reliable evidence to rate their effectiveness for the conditions they're marketed for, including digestive complaints and inflammatory bowel conditions. For many of the other ingredients in the blend, we don't have effectiveness data on file.

The evidence, ingredient by ingredient Lipase Lactase Phytase Proteolytic Enzymes (proteases)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The checked ingredients are generally well tolerated in most adults, but there are some caveats. Lipase, Phytase, and the Proteases may cause digestive upset or allergic reactions in sensitive people.

Rare occupational allergies to airborne Phytase and Proteases have been reported (mainly in workers handling powdered forms), and one case of contact dermatitis to Lactase powder was documented. People with serious digestive conditions should use this product only under medical guidance.

During pregnancy, the safety data are thin or absent for most ingredients — Lactase is likely safe, but check with your doctor before regular use of the others. Breastfeeding safety hasn't been well studied for any of these enzymes; ask your healthcare provider first.

Side effects, ingredient by ingredient Lipase Lactase Phytase Proteolytic Enzymes (proteases)

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 4 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That said, we hold no interaction data for about half the ingredients in this blend, so check your exact medications against the tool on this page before you start.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This product may help if you have trouble digesting certain foods, especially if you're lactose intolerant. People with inflammatory bowel disease or other serious digestive conditions should talk with their doctor before starting.

If you're pregnant or breastfeeding, or you take any regular medications, check with your pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 25 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vital-Zymes Complete, straight from the product label.

Brand Klaire Labs
Barcode (UPC) 709616310007
Net contents 120 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 265021
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vital-Zymes Complete by Klaire Labs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
UPC/BARCODE
709616310007
IngredientAmount% DV
Lipase0 NP--
Lactase0 NP--
Cellulase0 NP--
Phytase0 NP--
Glucoamylase0 NP--
Beta-Glucanase0 NP--
Alpha-Galactosidase0 NP--
Amylases0 NP--
Acid Proteases0 NP--
Maltase0 NP--
Hemicellulase/Pectinase/Phytase Complex0 NP--
Galactomannase0 NP--
Protein and Peptide Specific Enzymes0 NP--
Fat Specific Enzymes0 NP--
Other Enzymes0 NP--
Serratia peptidase0 NP--
Alpha-Amylases0 NP--
Carbohydrate Specific Enzymes0 NP--
Sugar Specific Enzymes0 NP--
Vegetable/Plant Fiber Specific Enzymes0 NP--
Comprehensive Enzyme Blend750 mg--
Sucrase0 NP--
Pullulanase0 NP--
Alkaline Proteases0 NP--
Proteases/Peptidase Complex0 NP--
Lysozyme0 NP--

Other ingredients: Hydroxypropyl Methylcellulose, Water, Ascorbyl Palmitate, Microcrystalline Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Comprehensive Enzyme Supplement

Brand IP Statement(s)

SFI

Peptizyme SP, a registered trademark of Specialty Enzymes

Precautions

Contains: Eggs.

Caution: If you are pregnant, nursing, have a medical condition, or taking prescription drugs, consult your physician before using this product.

Keep out of reach of children.

Do not use if shrinkwrap is broken or missing.

Formulation

Free of the following common allergens: Milk/casein, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.

Produced under a strict quality management system in compliance with Good Manufacturing Practices (GMPs) and third-party quality certifications.

Suggested/Recommended/Usage/Directions

Suggested Use: 2 capsules at the beginning of each meal or as directed by a healthcare professional.

Storage

Store in a cool, dry place (59 degrees F - 85 degrees F) away from direct light.

See for yourself

Vital-Zymes Complete by Klaire Labs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Vital-Zymes Complete by Klaire Labs

These are the 25 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Comprehensive Enzyme Blend

750 mg per serving
  • Lipase
  • Lactase
  • › Cellulase
  • Phytase
  • › Glucoamylase
  • › Beta-Glucanase
  • › Alpha-Galactosidase
  • › Amylases
  • Acid Proteases
  • › Maltase
  • › Hemicellulase/Pectinase/Phytase Complex
  • › Galactomannase
  • › Protein and Peptide Specific Enzymes
  • › Fat Specific Enzymes
  • › Other Enzymes
  • › Serratia peptidase
  • › Alpha-Amylases
  • › Carbohydrate Specific Enzymes
  • › Sugar Specific Enzymes
  • › Vegetable/Plant Fiber Specific Enzymes
  • › Sucrase
  • › Pullulanase
  • Alkaline Proteases
  • › Proteases/Peptidase Complex
  • › Lysozyme

Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Water, Ascorbyl Palmitate, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vital-Zymes Complete by Klaire Labs Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Vital-Zymes Complete. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Vital-Zymes Complete, from the product label.

Klaire Labs

See all Klaire Labs products
Name
SFI USA
City
Reno
State
NV
ZipCode
89521
Web Address
Klaire.com
Pharmacist Counseling Corner

Vital-Zymes Complete by Klaire Labs: Common Questions

Does Vital-Zymes Complete by Klaire Labs interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Vital-Zymes Complete. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Vital-Zymes Complete contains 25 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my lactose intolerance?
Lactase, one of the enzymes in this blend, is rated effective for lactose intolerance. If that's your main concern, this product may help you digest dairy products more comfortably.
Is it safe to take while I'm pregnant?
Lactase is likely safe during pregnancy, but most of the other enzymes in this blend don't have enough safety data to say. Talk with your doctor before taking it regularly while pregnant.
Can I take this if I'm breastfeeding?
Safety data on breastfeeding are limited or absent for the enzymes in this product. Check with your doctor or pharmacist before using it regularly while nursing.
What if I have a sensitive stomach?
These enzymes are generally well tolerated, but some people may experience digestive upset or allergic reactions. Start with the dose on the label, and if symptoms develop, stop and talk to your pharmacist.
Does this product have any fillers?
Yes — it contains inactive ingredients including hydroxypropyl methylcellulose, water, ascorbyl palmitate, and microcrystalline cellulose, which help form and preserve the capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vital-Zymes Complete is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vital-Zymes Complete label
Sources

Sources & How We Checked

Vital-Zymes Complete's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Phytase 7 references
  1. Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
  2. Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
  3. van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
  4. Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
  5. Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
  6. Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
  7. Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.

See these in context on the Phytase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring