Phosphatidic Acid Ingredients & Drug Interactions
by EPIQ
What is this page for?
First and foremost: checking Phosphatidic Acid against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Phosphatidic Acid is a dietary supplement by EPIQ with 3 active ingredients. Its ingredients are commonly taken for low testosterone or low libido in men, male fertility support, athletic performance and muscle strength.Based on those ingredients, 451 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Long Jack root extract, Astragalus root powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Phosphatidic Acid by EPIQ
Ask about any prescription or over-the-counter medication and we check it for interactions with Phosphatidic Acid by EPIQ — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Phosphatidic Acid by EPIQ
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.
Why this rating?
- The label discloses an exact amount for 0 of its 3 active ingredients.
- “Phosphatidic Acid Complex” is a proprietary blend — the label gives one combined amount (1,529 mg) without saying how much of each component you get.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 2 of the 3 matched ingredients can interact with medications — Astragalus, Eurycoma Longifolia.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: immunosuppressants / transplant drugs; diabetes medications; lithium.
- For scale: 451 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 3 of 3.
- General safety write-ups exist for 3 of 3.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2015.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Phosphatidic Acid, straight from the product label.
| Brand | EPIQ |
|---|---|
| Barcode (UPC) | 631656605211 |
| Net contents | 140 Softgel(s) |
| Market status | Off market |
| Date entered into DSLD | Feb 25, 2015 |
| DSLD ID | 42215 |
| Product type | Other Combinations |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Phosphatidic Acid by EPIQ, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Long Jack root extract | 0 NP | -- |
| Mediator(R) Phosphatidic Acid-enriched Soy Lecithin | 0 NP | -- |
| Phosphatidic Acid Complex | 1529 mg | -- |
| Astragalus root powder | 0 NP | -- |
Other ingredients: Medium Chain Triglyceride Oil, Mono- and Diglycerides, Silicon Dioxide, Gelatin, Glycerin, Caramel color, purified Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
DIRECTIONS: Take 1 serving (5 softgels) once daily. On workout days, take 30 minutes before training. Do not exceed 5 softgels in a 24-hour period. Read the entire label before use and follow directions provided.
Precautions
WARNING: For adult use only.
Do not use if pregnant or nursing.
KEEP OUT OF REACH OF CHILDREN.
Do not use if packaging has been tampered with.
Consult a medical doctor before use if you have a medical condition or before starting a diet or exercise program. Discontinue use two weeks prior to surgery.
Contains Soy Ingredients.
Storage
Store in a cool, dark place (60(0)F to 80(0)F)
Brand IP Statement(s)
Mediator(R) PA is protected under patents pending by Chemi Nutra. Mediator(R) PA is a registered trademark of Chemi Nutra.
(C) 2014.
EPIQ(TM)is a line of powerful, effective, and guaranteed clean supplements formulated for elite athletes who demand the highest quality for EPIQ(TM) performance.
What’s more, EPIQ(TM) PHOSPHATIDIC ACID gives you the most bioavailable form of oral phosphatidic acid, and it keeps your level of phosphatidic acid raised for hours!
Start maximizing your musclebuilding potential with EPIQ(TM) PHOSPHATIDIC ACID!
STACK WITH: EPIQ(TM) SUPPLEMENT
CLEAN SUPPLEMENTS FOR EPIQ(TM) PERFORMANCE
General Statements
Made in the U.S.A. from international ingredients.
Patent pending. For lot no. and expiry date: see box.
Twitter @epiqresults Facebook.com/epiqresults
~ Developed with a scientifically researched key ingredient~ Manufactured according to current Good Manufacturing Practices (cGMP) standards, as is required for all dietary supplements ~ Made in the U.S.A. from international ingredients
100% Ultra-Pure Formula
What you’re holding in your hands is one of the most exciting new muscle and strength compounds ever researched!
Yes, you read that right – DOUBLE the gains! Want proof? 1In a recent study at the University of Tampa on 28 resistancetrained subjects, those who trained 3 times a week and took phosphatidic acid for 8 weeks actually DOUBLED the amount of muscle they gained compared to subjects following the same training protocol, but who were taking a placebo.
It’s time to truly experience results from your hard work in the gym.
~ 1In an 8-week clinical study published in Nutrition & Metabolism, resistance-trained subjects taking phosphatidic acid achieved a 100% greater increase in lean body mass and increased 1-rep max leg press by 60% more than subjects using a placebo. ~ 2In a separate phase of the same study, pre-clinical research showed that phosphatidic acid increased mTOR signalling by over 6 times compared to baseline.
SCIENTIFICALLY STUDIES KEY INGREDIENTS
4- WEEK SUPPLY
NEW!
Powerful Muscle Growth Activator
CLINICALLY DOSED KEY DRIVER
~ Subjects Gained 5.3 lbs. of Muscle in 8 Weeks,1 ~ Double Your Muscle Gains,1 ~ 60% Increase in Muscle Strength,1 ~ Increased mTOR Signalling by More Than 6 Times,2
Results based on core ingredient testing. See back of label for study details
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formulation
EPIQ(TM) Guaranteed Supplements are:~ Free of banned substances ~ Free of artificial colors or dyes ~ Free of harmful impurities ~ Free of undeclared ingredients
GUARANTEED BANNED SUBSTANCE FREE
Formula
EPIQ(TM) PHOSPHATIDIC ACID contains a clinically studied musclebuilding compound that can DOUBLE your training results.
What Makes the Formula(TM)? ~ Each serving of EPIQTM PHOSPHATIDIC ACID delivers 750mg of the world’s most pure phosphatidic acid in just one serving!
Contains Soy Ingredients.
General
10341US 0914
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Phosphatidic Acid by EPIQ label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Phosphatidic Acid by EPIQ
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size5 Softgel(s) Dosage formSoftgel Capsule Servings per container28 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Phosphatidic Acid Complex
Other (inactive) ingredients: Medium Chain Triglyceride Oil, Mono- and Diglycerides, Silicon Dioxide, Gelatin, Glycerin, Caramel color, Purified Water. These complete the product’s ingredient list but are not active constituents.
Phosphatidic Acid by EPIQ Drug Interactions
Phosphatidic Acid contains 3 ingredients, and 2 of them have known drug interactions. Altogether they interact with 451 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Phosphatidic Acid?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Phosphatidic Acid interact with 451 drugs. Click any drug to see the details.
2 of the 3 ingredients in Phosphatidic Acid interact with drugs. Each result below shows which ingredient is responsible. Long Jack root extract Astragalus root powder
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + 6-mercaptopurine interactionAbrocitinibCibinqo
How Abrocitinib interacts with Phosphatidic Acid — through 2 ingredients. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Abrocitinib interactionLong Jack Root ExtractCytochrome P450 2c19 (cyp2c19) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
Read the full Long Jack Root Extract + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Powder + Acarbose interactionAcetohexamideDymelor
How Acetohexamide interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Powder + Acetohexamide interactionAdalimumabHumira
How Adalimumab interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Adalimumab-fkjp interactionAlbiglutideTanzeum
How Albiglutide interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Powder + Albiglutide interactionAlefaceptAmevive
How Alefacept interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Alemtuzumab interactionAlogliptinNesina
How Alogliptin interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Powder + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Powder + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Powder + Alogliptin, Pioglitazone interactionAnifrolumab-fniaSaphnelo
How Anifrolumab-fnia interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Anifrolumab-fnia interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Powder + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithymocyte GlobulinThymoglobulin
How Antithymocyte Globulin interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Antithymocyte Globulin interactionAtezolizumabTecentriq
How Atezolizumab interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Atezolizumab interactionAzamuneImmunoprin
How Azamune interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Azamune interactionAzathioprineAzamune, Imuran
How Azathioprine interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Azathioprine interactionBasiliximabSimulect
How Basiliximab interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Basiliximab interactionBeclometasone DipropionateBecotide
How Beclometasone Dipropionate interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Beclometasone Dipropionate interactionBeclomethasoneBeclovent, Vanceril
How Beclomethasone interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Beclomethasone interactionBeclomethasone DipropionateQNASL, Qvar
How Beclomethasone Dipropionate interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Beclomethasone Dipropionate interactionBetamethasoneCelestone, Diprolene AF, Diprosone
How Betamethasone interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Betamethasone interactionBetamethasone DipropionateSernivo
How Betamethasone Dipropionate interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Betamethasone Dipropionate interactionBetamethasone Dipropionate, CalcipotrieneEnstilar, Wynzora
How Betamethasone Dipropionate, Calcipotriene interacts with Phosphatidic Acid — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Powder + Betamethasone Dipropionate, Calcipotriene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Phosphatidic Acid with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Long Jack root extract
Propranolol (Inderal)
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.
Cytochrome P450 2A6 (Cyp2A6) Substrates
Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.
Testosterone
Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.
Astragalus root powder
Antidiabetes Drugs
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.
Cyclophosphamide
Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.
Immunosuppressants
Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.
Lithium
Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.
Brand information
Manufacturer and brand details for Phosphatidic Acid, from the product label.
EPIQ
See all EPIQ products- Name
- Iovate Health Sciences U.S.A. Inc.
- Street Address
- 1105 N. Market St., Ste. 1330
- City
- Wilmington
- State
- DE
- ZipCode
- 19801
Phosphatidic Acid by EPIQ: Common Questions
Does Phosphatidic Acid by EPIQ interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Phosphatidic Acid is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Phosphatidic Acid’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Eurycoma Longifolia
Interacts with 248 drugsEurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small human studies suggesting possible benefits....
Read the full Eurycoma Longifolia monograph → Herb & supplement monographLecithin
Lecithin is a natural fatty substance found in foods and made by the body that is widely used as a supplement and food emulsifier. Evidence supporting most of its health claims is limited, t...
Read the full Lecithin monograph → Herb & supplement monographAstragalus
Interacts with 208 drugsAstragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While early studies are interesting, strong h...
Read the full Astragalus monograph →Sources & How We Checked
Phosphatidic Acid's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 26 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Eurycoma Longifolia 4 references
- Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
- Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
- Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
- Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent
Lecithin 9 references
- Buchman AL, Dubin M, Jenden D, et al. Lecithin increases plasma free choline and decreases hepatic steatosis in long-term total parenteral nutrition patients. Gastroenterology 1992;102:1363-70.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
- Chatellier G, Lacomblez L. Tacrine (tetrahydroaminoacridine; THA) and lecithin in senile dementia of the Alzheimer type: a multicentre trial. Groupe Francais d'Etude de la Tetrahydroaminoacridine. BMJ 1990;300:495-9.
- Gelenberg AJ, Dorer DJ, Wojcik JD, et al. A crossover study of lecithin treatment of tardive dyskinesia. J Clin Psychiatry 1990;51:149-53.
- Little A, Levy R, Chuaqui-Kidd P, Hand D. A double-blind, placebo controlled trial of high-dose lecithin in Alzheimer's disease. J Neurol Neurosurg Psychiatry 1985;48:736-42. PubMed
- Palm M, Moneret-Vautrin DA, Kanny G, et al. Food allergy to egg and soy lecithins. Allergy 1999;54:1116-7. PubMed
- Drachman DA, Glosser G, Fleming P, et al. Memory decline in the aged: treatment with lecithin and physostigmine. Neurology 1982;32:944-50. PubMed
- Gelenberg, A. J., Doller-Wojcik, J. C., and Growdon, J. H. Choline and lecithin in the treatment of tardive dyskinesia: preliminary results from a pilot study. Am J Psychiatry 1979;136(6):772-776. PubMed
- Electronic Code of Federal Regulations. Title 21, Chapter 1, Subchapter B, Part 184: Direct food substances affirmed as Generally Recognized as Safe. Subpart B - listing of specific substances affirmed as GRAS. Sec. 184.1400 Lecithin. Available at: https:
Astragalus 13 references
- Upton R, ed. Astragalus Root: Analytical, quality control, and therapeutic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia. 1999:1-25.
- Khoo KS, Ang PT. Extract of astragalus membranaceus and ligustrum lucidum does not prevent cyclophosphamide-induced myelosuppression. Singapore Med J 1995;36:387-90.
- Chu DT, Wong WL, Mavligit GM. Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo. J Clin Lab Immunol 1988;25:125-9.
- Sun Y, Hersh EM, Lee SL, et al. Preliminary observations on the effects of the Chinese medicinal herbs Astragalus membranaceus and Ligustrum lucidum on lymphocyte blastogenic responses. J Biol Response Mod 1983;2:227-37..
- Ma J, Peng A, Lin S. Mechanisms of the therapeutic effect of astragalus membranaceus on sodium and water retention in experimental heart failure. Chin Med J (Engl) 1998;111:17-23.
- Matkovic Z, Zivkovic V, Korica M, et al. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. Phytother Res 2010;24:175-81.
- Zhang, J. G., Yang, N., He, H., Wei, G. H., Gao, D. S., Wang, X. L., Wang, X. Z., and Song, G. Y. [Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure.]. Chin J Integr.Med 2005;11(3):18 PubMed
- Chen, H. W., Lin, I. H., Chen, Y. J., Chang, K. H., Wu, M. H., Su, W. H., Huang, G. C., and Lai, Y. L. A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: a phase II double-blind, randomized placebo-controlled study. Clin Invest PubMed
- Tian H, Lu J, He H, et al.The effect of Astragalus as an adjuvant treatment in type 2 diabetes mellitus: A (preliminary) meta-analysis. J Ethnopharmacol. 2016;191:206-215. doi: 10.1016/j.jep.2016.05.062. PubMed
- Hong KF, Liu PY, Zhang W, Gui DK, Xu YH. The Efficacy and Safety of Astragalus as an Adjuvant Treatment for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. J Integr Complement Med 2023. PubMed
- Chan KW, Kwong ASK, Tsui PN, et al. Add-on astragalus in type 2 diabetes and chronic kidney disease: A multi-center, assessor-blind, randomized controlled trial. Phytomedicine 2024;130:155457. PubMed
- Han X, Yu T, Chen X, Du Z, Yu M, Xiong J. Effect of Astragalus membranaceus on left ventricular remodeling in HFrEF: a systematic review and meta-analysis. Front Pharmacol 2024;15:1345797. PubMed
- Jing P, Hongzheng H, Zhenqi WU, Meijuan Z, Zuojing LI, Gang C. Long-term efficacy and safety of Huangqi ()-based Traditional Chinese Medicine in diabetic peripheral neuropathy: a Meta-analysis of randomized controlled trials. J Tradit Chin Med 2024;44(2):
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