Dapagliflozin

Generic name: Pronounced as (dap'' a gli floe' zin)
Brand names
  • Farxiga®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 07/15/2021

Dapagliflozin is used along with diet and exercise, and sometimes with other medications, to lower blood sugar levels in adults with type 2 diabetes (condition in which blood sugar is too high because the body does not produce or use insulin normally). It is also used to reduce the risk of needing to be hospitalized for heart failure in adults who have type 2 diabetes along with heart and blood vessel disease or who have multiple risk factors for developing heart and blood vessel disease. Dapagliflozin is also used in adults with heart failure to reduce the risk of needing to be hospitalized and death due to heart and blood vessel disease. It is also used to reduce the risk of worsening kidney disease, the need to be hospitalized for heart failure, and the risk of death due to heart disease in adults with kidney disease. Dapagliflozin is in a class of medications called sodium-glucose co-transporter 2 (SGLT2) inhibitors. It lowers blood sugar by causing the kidneys to get rid of more glucose in the urine. Dapagliflozin is not used to treat type 1 diabetes (condition in which the body does not produce insulin and, therefore, cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may develop if high blood sugar is not treated).

Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Taking dapagliflozin, making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numb, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes.

Dapagliflozin comes as a tablet to take by mouth. It is taken usually with or without food once a day. Take dapagliflozin at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take dapagliflozin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor may start you on a low dose of dapagliflozin and increase your dose if needed.

Dapagliflozin helps to control your condition, but does not cure it. Continue to take dapagliflozin even if you feel well. Do not stop taking dapagliflozin without talking to your doctor.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with dapagliflozin and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) to obtain the Medication Guide.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking dapagliflozin,

  • tell your doctor and pharmacist if you are allergic to dapagliflozin, any other medications, or any of the ingredients in dapagliflozin tablets. Ask your pharmacist or check the Medication Guide for a list of the ingredients.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin, in Lotrel), captopril, enalapril (Vasotec, in Vaseretic), fosinopril, lisinopril (in Zestoretic), moexipril (Univasc, in Uniretic), perindopril (Aceon, in Prestalia), ramipril (Altace), and trandolapril (Mavik, in Tarka); angiotensin receptor blockers (ARB) such as azilsartan (Edarbi, in Edarbyclor), candesartan (Atacand, in Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, in Avalide), losartan (Cozaar, in Hyzaar), olmesartan (Benicar, in Azor, in Benicar HCT, in Tribenzor), telmisartan (Micardis, in Micardis HCT, in Twynsta); aspirin and other nonsteroidal anti-inflammatory medications (NSAIDS) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); diabetes medications such as glimepiride (Amaryl, in Duetact), glipizide (Glucotrol), glyburide (DiaBeta, Glynase), repaglinide (Prandin, in Prandimet), and tolbutamide; diuretics ('water pills'); and insulin.

  • tell your doctor if you are on dialysis. Your doctor may tell you not to take dapagliflozin.

  • tell your doctor if you regularly drink alcohol or sometimes drink large amounts of alcohol in a short time (binge drinking) or if you are on a low sodium diet. Also tell your doctor if you have or have ever had heart failure, pancreatic disease including pancreatitis (swelling of the pancreas) or have had surgery on your pancreas, urinary tract infections or problems urinating, low blood pressure, yeast infections in the genital area, kidney or liver disease. If you are male, tell your doctor if you have never been circumcised. Also, tell your doctor, if you are eating less due to illness, surgery or a change in your diet, or have recently had diarrhea, vomiting, not been drinking enough fluids, been in the sun too long, or have been sweating a lot, which may cause dehydration (loss of a large amount of body fluids).

  • tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. Do not breastfeed while you are taking dapagliflozin. If you become pregnant while taking dapagliflozin, call your doctor.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking dapagliflozin. Your doctor will probably tell you to stop taking dapagliflozin at least 3 days before a surgery.

  • alcohol may cause a change in blood sugar. Ask your doctor about the safe use of alcoholic beverages while you are taking dapagliflozin.

  • you should know that dapagliflozin may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. If you have this problem, call your doctor. This problem is more common when you first start taking dapagliflozin. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.

  • ask your doctor what to do if you get sick, develop an infection or fever, experience unusual stress, or are injured. These conditions can affect your blood sugar and the amount of dapagliflozin you may need.

Be sure to follow all exercise and dietary recommendations made by your doctor or dietitian. It is important to eat a healthful diet and exercise regularly.

Follow your doctor's instructions about drinking enough fluids throughout the day while you are on this medication.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

This medication may cause changes in your blood sugar. You should know the symptoms of low and high blood sugar and what to do if you have these symptoms.

  • Dapagliflozin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • urinating a lot, including at night

    • increased thirst

  • Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

    • frequent, urgent, burning, or painful urination

    • urine that is cloudy, red, pink, or brown

    • strong smelling urine

    • decrease in amount of urine

    • pelvic or rectal pain

    • (in women) vaginal odor, white or yellowish vaginal discharge (may be lumpy or look like cottage cheese), or vaginal itching

    • (in men) redness, itching, or swelling of the penis; rash on the penis; foul smelling discharge from the penis; or pain in the skin around the penis

    • feeling tired, weak, or uncomfortable; along with a fever and pain, tenderness, redness, and swelling of the genitals or the area between the genitals and the rectum

    • swelling of the legs or feet

  • If you experience any of the following symptoms, stop taking dapagliflozin and call your doctor immediately or get emergency medical treatment:

    • rash

    • hives

    • itching

    • difficulty breathing or swallowing

    • swelling of the face, throat, tongue, lips, mouth, or eyes

    • hoarseness

  • If you experience any of the following symptoms of ketoacidosis, stop taking dapagliflozin and call your doctor immediately or get emergency medical treatment. If possible, check for ketones in your urine if you have these symptoms, even if your blood sugar is less than 250 mg/dL:

    • nausea

    • vomiting

    • stomach-area pain

    • tiredness

    • difficulty breathing

  • Dapagliflozin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor and the laboratory. Your doctor will probably order certain laboratory tests before and during your treatment to check your body's response to dapagliflozin.

Your blood sugar levels should be checked regularly to determine your response to dapagliflozin. Your doctor will order other lab tests, including glycosylated hemoglobin (HbA1c), to check your response to dapagliflozin. Your doctor will also tell you how to check your response to this medication by measuring your blood sugar levels at home. Follow these instructions carefully.

Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking dapagliflozin. Because of the way this medication works, your urine may test positive for glucose.

You should always wear a diabetic identification bracelet to be sure you get proper treatment in an emergency.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

  • Qtern® (containing Dapagliflozin, Saxagliptin)
  • Qternmet® XR (containing Dapagliflozin, Metformin, Saxagliptin)
  • Xigduo® XR (containing Dapagliflozin, Metformin)

Drug Interaction
Moxifloxacin Moxifloxacin The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Moxifloxacin.
Repaglinide Repaglinide Dapagliflozin may increase the hypoglycemic activities of Repaglinide.
Montelukast Montelukast The metabolism of Dapagliflozin can be decreased when combined with Montelukast.
Insulin Glargine (rDNA origin) Injection Insulin Glargine (rDNA origin) Injection Dapagliflozin may increase the hypoglycemic activities of Insulin glargine.
Leflunomide Leflunomide The serum concentration of Dapagliflozin can be decreased when it is combined with Leflunomide.
Delavirdine Delavirdine The metabolism of Dapagliflozin can be decreased when combined with Delavirdine.
Nevirapine Nevirapine The metabolism of Dapagliflozin can be decreased when combined with Nevirapine.
Dolasetron Dolasetron The metabolism of Dapagliflozin can be decreased when combined with Dolasetron.
Aminophylline Aminophylline The metabolism of Aminophylline can be decreased when combined with Dapagliflozin.
Anagrelide Anagrelide The metabolism of Anagrelide can be decreased when combined with Dapagliflozin.
Bisacodyl Bisacodyl The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Bisacodyl.
Candesartan Candesartan The metabolism of Dapagliflozin can be decreased when combined with Candesartan.
Cilostazol Cilostazol The metabolism of Cilostazol can be decreased when combined with Dapagliflozin.
Clopidogrel Clopidogrel The metabolism of Clopidogrel can be decreased when combined with Dapagliflozin.
Diphenoxylate Diphenoxylate The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Diphenoxylate.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The metabolism of Conjugated estrogens can be decreased when combined with Dapagliflozin.
Fenofibrate Fenofibrate The metabolism of Dapagliflozin can be decreased when combined with Fenofibrate.
Guanfacine Guanfacine Dapagliflozin may increase the excretion rate of Guanfacine which could result in a lower serum level and potentially a reduction in efficacy.
Magnesium Hydroxide Magnesium Hydroxide The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Magnesium hydroxide.
Magnesium Oxide Magnesium Oxide The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Magnesium oxide.
Miglitol Miglitol Dapagliflozin may increase the hypoglycemic activities of Miglitol.
Mycophenolate Mycophenolate Dapagliflozin may increase the excretion rate of Mycophenolic acid which could result in a lower serum level and potentially a reduction in efficacy.
Olsalazine Olsalazine Olsalazine may increase the hypoglycemic activities of Dapagliflozin.
Paregoric Paregoric The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Morphine.
Penbutolol Penbutolol The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Acebutolol.
Pentazocine Pentazocine The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Pentazocine.
Polyethylene glycol-electrolyte solution (PEG-ES) Polyethylene glycol-electrolyte solution (PEG-ES) The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Polyethylene glycol.
Potassium Potassium Dapagliflozin may increase the excretion rate of Potassium cation which could result in a lower serum level and potentially a reduction in efficacy.
Prednisone Prednisone The risk or severity of hyperglycemia can be increased when Prednisone is combined with Dapagliflozin.
Psyllium Psyllium The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Plantago seed.
Ranitidine Ranitidine The metabolism of Ranitidine can be decreased when combined with Dapagliflozin.
Reserpine Reserpine Dapagliflozin may increase the excretion rate of Reserpine which could result in a lower serum level and potentially a reduction in efficacy.
Rizatriptan Rizatriptan Dapagliflozin may increase the excretion rate of Rizatriptan which could result in a lower serum level and potentially a reduction in efficacy.
Sumatriptan Sumatriptan The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Sumatriptan.
Tacrolimus Tacrolimus The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Tacrolimus.
Tizanidine Tizanidine The metabolism of Tizanidine can be decreased when combined with Dapagliflozin.
Triamcinolone Triamcinolone The risk or severity of hyperglycemia can be increased when Triamcinolone is combined with Dapagliflozin.
Zolmitriptan Zolmitriptan The metabolism of Zolmitriptan can be decreased when combined with Dapagliflozin.
Ampicillin Injection Ampicillin Injection Dapagliflozin may increase the excretion rate of Ampicillin which could result in a lower serum level and potentially a reduction in efficacy.
Doxycycline Injection Doxycycline Injection Dapagliflozin may increase the excretion rate of Doxycycline which could result in a lower serum level and potentially a reduction in efficacy.
Famotidine Injection Famotidine Injection The metabolism of Dapagliflozin can be decreased when combined with Famotidine.
Fluconazole Injection Fluconazole Injection The risk or severity of hypoglycemia can be increased when Dapagliflozin is combined with Fluconazole.
Hydromorphone Injection Hydromorphone Injection The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Hydromorphone.
Interferon Beta-1b Injection Interferon Beta-1b Injection The metabolism of Dapagliflozin can be decreased when combined with Interferon beta-1b.
Interferon Gamma-1b Injection Interferon Gamma-1b Injection The metabolism of Dapagliflozin can be decreased when combined with Interferon gamma-1b.
Levofloxacin Injection Levofloxacin Injection The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Levofloxacin.
Meperidine Injection Meperidine Injection The metabolism of Dapagliflozin can be increased when combined with Meperidine.
Methylprednisolone Injection Methylprednisolone Injection The risk or severity of hyperglycemia can be increased when Methylprednisolone is combined with Dapagliflozin.
Metoclopramide Injection Metoclopramide Injection The metabolism of Dapagliflozin can be decreased when combined with Metoclopramide.
Metronidazole Injection Metronidazole Injection The metabolism of Dapagliflozin can be decreased when combined with Metronidazole.
Morphine Injection Morphine Injection The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Morphine.
Vancomycin Injection Vancomycin Injection Dapagliflozin may increase the excretion rate of Vancomycin which could result in a lower serum level and potentially a reduction in efficacy.
Zidovudine Injection Zidovudine Injection The metabolism of Dapagliflozin can be decreased when combined with Zidovudine.
Altretamine Altretamine Amphetamine may increase the orthostatic hypotensive activities of Dapagliflozin.
Cyclosporine Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Dapagliflozin.
Ondansetron Ondansetron The metabolism of Dapagliflozin can be decreased when combined with Ondansetron.
Torsemide Torsemide The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Torasemide.
Olanzapine Olanzapine The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Olanzapine.
Alosetron Alosetron The metabolism of Alosetron can be decreased when combined with Dapagliflozin.
Entacapone Entacapone The metabolism of Dapagliflozin can be decreased when combined with Entacapone.
Eprosartan Eprosartan The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Eprosartan.
Hydroxychloroquine Hydroxychloroquine The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Hydroxychloroquine.
Meloxicam Meloxicam The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Meloxicam.
Pantoprazole Pantoprazole Dapagliflozin may increase the excretion rate of Pantoprazole which could result in a lower serum level and potentially a reduction in efficacy.
Telmisartan Telmisartan The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Telmisartan.
Temozolomide Temozolomide Dapagliflozin may increase the excretion rate of Temozolomide which could result in a lower serum level and potentially a reduction in efficacy.
Zaleplon Zaleplon Dapagliflozin may increase the excretion rate of Zaleplon which could result in a lower serum level and potentially a reduction in efficacy.
Anakinra Anakinra The metabolism of Dapagliflozin can be increased when combined with Anakinra.
Linezolid Linezolid Linezolid may increase the orthostatic hypotensive activities of Dapagliflozin.
Trimipramine Trimipramine The metabolism of Dapagliflozin can be decreased when combined with Trimipramine.
Etanercept Injection Etanercept Injection The metabolism of Dapagliflozin can be increased when combined with Etanercept.
Modafinil Modafinil The metabolism of Dapagliflozin can be increased when combined with Modafinil.
Perindopril Perindopril The risk or severity of renal failure, hypotension, and hyperkalemia can be increased when Dapagliflozin is combined with Perindopril.
Tenofovir Tenofovir Dapagliflozin may increase the excretion rate of Tenofovir which could result in a lower serum level and potentially a reduction in efficacy.
Sirolimus Sirolimus The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Sirolimus.
Epinephrine Injection Epinephrine Injection The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Epinephrine.
Eplerenone Eplerenone The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Eplerenone.
Escitalopram Escitalopram The serum concentration of Dapagliflozin can be increased when it is combined with Escitalopram.
Olmesartan Olmesartan The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Olmesartan.
Zonisamide Zonisamide The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Zonisamide.
Adalimumab Injection Adalimumab Injection The metabolism of Dapagliflozin can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Aripiprazole.
Atomoxetine Atomoxetine Dapagliflozin may increase the excretion rate of Atomoxetine which could result in a lower serum level and potentially a reduction in efficacy.
Atazanavir Atazanavir The metabolism of Dapagliflozin can be decreased when combined with Atazanavir.
Almotriptan Almotriptan Dapagliflozin may increase the excretion rate of Almotriptan which could result in a lower serum level and potentially a reduction in efficacy.
Eletriptan Eletriptan The metabolism of Dapagliflozin can be increased when combined with Eletriptan.
Mefloquine Mefloquine The metabolism of Dapagliflozin can be decreased when combined with Mefloquine.
Polyethylene Glycol 3350 Polyethylene Glycol 3350 The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Polyethylene glycol.
Rosuvastatin Rosuvastatin The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Rosuvastatin.
Vardenafil Vardenafil The risk or severity of hypotension can be increased when Vardenafil is combined with Dapagliflozin.
Aprepitant Aprepitant The metabolism of Dapagliflozin can be decreased when combined with Aprepitant.
Emtricitabine Emtricitabine Dapagliflozin may increase the excretion rate of Emtricitabine which could result in a lower serum level and potentially a reduction in efficacy.
Interferon Beta-1a Subcutaneous Injection Interferon Beta-1a Subcutaneous Injection The metabolism of Dapagliflozin can be decreased when combined with Interferon beta-1a.
Memantine Memantine Memantine may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Tegaserod Tegaserod The metabolism of Dapagliflozin can be decreased when combined with Tegaserod.
Tadalafil Tadalafil Dapagliflozin may increase the excretion rate of Tadalafil which could result in a lower serum level and potentially a reduction in efficacy.
Fosamprenavir Fosamprenavir The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Fosamprenavir.
Frovatriptan Frovatriptan The metabolism of Frovatriptan can be decreased when combined with Dapagliflozin.
Gemifloxacin Gemifloxacin The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Gemifloxacin.
Progesterone Progesterone The metabolism of Dapagliflozin can be decreased when combined with Progesterone.
Apomorphine Injection Apomorphine Injection The risk or severity of adverse effects can be increased when Apomorphine is combined with Dapagliflozin.
Infliximab Injection Infliximab Injection The metabolism of Dapagliflozin can be increased when combined with Infliximab.
Oxandrolone Oxandrolone The metabolism of Dapagliflozin can be decreased when combined with Oxandrolone.
Protriptyline Protriptyline Protriptyline may decrease the hypoglycemic activities of Dapagliflozin.
Duloxetine Duloxetine The risk or severity of orthostatic hypotension and syncope can be increased when Dapagliflozin is combined with Duloxetine.
Norethindrone Norethindrone The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Norethisterone.
Tinidazole Tinidazole Dapagliflozin may increase the excretion rate of Tinidazole which could result in a lower serum level and potentially a reduction in efficacy.
Trospium Trospium The metabolism of Dapagliflozin can be decreased when combined with Trospium.
Bosentan Bosentan The metabolism of Dapagliflozin can be increased when combined with Bosentan.
Cefditoren Cefditoren Dapagliflozin may increase the excretion rate of Cefdinir which could result in a lower serum level and potentially a reduction in efficacy.
Cinacalcet Cinacalcet The metabolism of Dapagliflozin can be decreased when combined with Cinacalcet.
Cyanocobalamin Injection Cyanocobalamin Injection Dapagliflozin may increase the excretion rate of Hydroxocobalamin which could result in a lower serum level and potentially a reduction in efficacy.
Erlotinib Erlotinib The metabolism of Erlotinib can be decreased when combined with Dapagliflozin.
Eszopiclone Eszopiclone Dapagliflozin may increase the excretion rate of Eszopiclone which could result in a lower serum level and potentially a reduction in efficacy.
Ganciclovir Ganciclovir Dapagliflozin may increase the excretion rate of Ganciclovir which could result in a lower serum level and potentially a reduction in efficacy.
Insulin Aspart (rDNA Origin) Injection Insulin Aspart (rDNA Origin) Injection Dapagliflozin may increase the hypoglycemic activities of Insulin aspart.
Ribavirin Ribavirin Dapagliflozin may increase the excretion rate of Ribavirin which could result in a lower serum level and potentially a reduction in efficacy.
Solifenacin Solifenacin The metabolism of Dapagliflozin can be decreased when combined with Solifenacin.
Valganciclovir Valganciclovir Dapagliflozin may increase the excretion rate of Valganciclovir which could result in a lower serum level and potentially a reduction in efficacy.
Voriconazole Voriconazole The metabolism of Dapagliflozin can be decreased when combined with Voriconazole.
Dextroamphetamine Dextroamphetamine Amphetamine may increase the orthostatic hypotensive activities of Dapagliflozin.
Entecavir Entecavir The metabolism of Entecavir can be decreased when combined with Dapagliflozin.
Peginterferon Alfa-2a Injection Peginterferon Alfa-2a Injection The metabolism of Dapagliflozin can be decreased when combined with Peginterferon alfa-2a.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The serum concentration of Dapagliflozin can be increased when it is combined with Peginterferon alfa-2b.
Pramlintide Injection Pramlintide Injection Dapagliflozin may increase the hypoglycemic activities of Pramlintide.
Exenatide Injection Exenatide Injection Dapagliflozin may increase the hypoglycemic activities of Exenatide.
Isocarboxazid Isocarboxazid Isocarboxazid may increase the orthostatic hypotensive activities of Dapagliflozin.
Ramelteon Ramelteon The metabolism of Ramelteon can be decreased when combined with Dapagliflozin.
Darifenacin Darifenacin The metabolism of Darifenacin can be decreased when combined with Dapagliflozin.
Fentanyl Fentanyl Dapagliflozin may increase the excretion rate of Fentanyl which could result in a lower serum level and potentially a reduction in efficacy.
Pregabalin Pregabalin The risk or severity of hypoglycemia can be increased when Pregabalin is combined with Dapagliflozin.
Deferasirox Deferasirox The serum concentration of Dapagliflozin can be increased when it is combined with Deferasirox.
Phenylephrine Phenylephrine The metabolism of Dapagliflozin can be increased when combined with Phenylephrine.
Tipranavir Tipranavir The metabolism of Tipranavir can be decreased when combined with Dapagliflozin.
Felbamate Felbamate The metabolism of Dapagliflozin can be decreased when combined with Felbamate.
Insulin Detemir (rDNA Origin) Injection Insulin Detemir (rDNA Origin) Injection Dapagliflozin may increase the hypoglycemic activities of Insulin detemir.
Ranolazine Ranolazine The serum concentration of Dapagliflozin can be increased when it is combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Dapagliflozin can be increased when combined with Abatacept.
Rasagiline Rasagiline Rasagiline may increase the orthostatic hypotensive activities of Dapagliflozin.
Imatinib Imatinib The metabolism of Dapagliflozin can be decreased when combined with Imatinib.
Sitagliptin Sitagliptin Dapagliflozin may increase the hypoglycemic activities of Sitagliptin.
Varenicline Varenicline Dapagliflozin may increase the excretion rate of Varenicline which could result in a lower serum level and potentially a reduction in efficacy.
Gefitinib Gefitinib The metabolism of Dapagliflozin can be decreased when combined with Gefitinib.
Albuterol Albuterol Dapagliflozin may increase the excretion rate of Salbutamol which could result in a lower serum level and potentially a reduction in efficacy.
Paliperidone Paliperidone The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Paliperidone.
Bortezomib Bortezomib The metabolism of Bortezomib can be decreased when combined with Dapagliflozin.
Clofarabine Injection Clofarabine Injection Clofarabine may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Insulin Glulisine (rDNA origin) Injection Insulin Glulisine (rDNA origin) Injection Dapagliflozin may increase the hypoglycemic activities of Insulin glulisine.
Lubiprostone Lubiprostone The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Lubiprostone.
Primaquine Primaquine The metabolism of Dapagliflozin can be decreased when combined with Primaquine.
Aliskiren Aliskiren The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Aliskiren.
Bismuth Subsalicylate Bismuth Subsalicylate Bismuth subsalicylate may increase the hypoglycemic activities of Dapagliflozin.
Darunavir Darunavir The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Darunavir.
Pemetrexed Injection Pemetrexed Injection The metabolism of Pemetrexed can be decreased when combined with Dapagliflozin.
Lisdexamfetamine Lisdexamfetamine The metabolism of Dapagliflozin can be decreased when combined with Lisdexamfetamine.
Nabilone Nabilone The metabolism of Dapagliflozin can be decreased when combined with Nabilone.
Vorinostat Vorinostat The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Vorinostat.
Sorafenib Sorafenib The metabolism of Dapagliflozin can be decreased when combined with Sorafenib.
Sunitinib Sunitinib Dapagliflozin may increase the hypoglycemic activities of Sunitinib.
Dronabinol Dronabinol The metabolism of Dapagliflozin can be decreased when combined with Dronabinol.
Levocetirizine Levocetirizine Dapagliflozin may increase the excretion rate of Levocetirizine which could result in a lower serum level and potentially a reduction in efficacy.
Pegaptanib Injection Pegaptanib Injection Dapagliflozin may increase the excretion rate of Pegaptanib which could result in a lower serum level and potentially a reduction in efficacy.
Dasatinib Dasatinib The metabolism of Dasatinib can be decreased when combined with Dapagliflozin.
Mexiletine Mexiletine The metabolism of Mexiletine can be decreased when combined with Dapagliflozin.
Armodafinil Armodafinil The metabolism of Dapagliflozin can be decreased when combined with Armodafinil.
Azacitidine Injection Azacitidine Injection Dapagliflozin may increase the excretion rate of Azacitidine which could result in a lower serum level and potentially a reduction in efficacy.
Paclitaxel (with polyoxyethylated castor oil) Injection Paclitaxel (with polyoxyethylated castor oil) Injection The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Castor oil.
Temsirolimus Temsirolimus The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Temsirolimus.
Lenalidomide Lenalidomide Dapagliflozin may increase the excretion rate of Lenalidomide which could result in a lower serum level and potentially a reduction in efficacy.
Nilotinib Nilotinib The metabolism of Dapagliflozin can be decreased when combined with Nilotinib.
Bexarotene Bexarotene The metabolism of Dapagliflozin can be decreased when combined with Bexarotene.
Budesonide Budesonide The risk or severity of hyperglycemia can be increased when Budesonide is combined with Dapagliflozin.
Desmopressin Desmopressin Dapagliflozin may increase the excretion rate of Desmopressin which could result in a lower serum level and potentially a reduction in efficacy.
Doripenem Injection Doripenem Injection Dapagliflozin may increase the excretion rate of Doripenem which could result in a lower serum level and potentially a reduction in efficacy.
Etravirine Etravirine The metabolism of Dapagliflozin can be decreased when combined with Etravirine.
Arsenic Trioxide Injection Arsenic Trioxide Injection The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Arsenic trioxide.
Desvenlafaxine Desvenlafaxine The risk or severity of hypoglycemia can be increased when Desvenlafaxine is combined with Dapagliflozin.
Cevimeline Cevimeline Dapagliflozin may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy.
Nebivolol Nebivolol The therapeutic efficacy of Nebivolol can be increased when used in combination with Dapagliflozin.
Tretinoin Tretinoin The metabolism of Dapagliflozin can be decreased when combined with Tretinoin.
Bendamustine Injection Bendamustine Injection The metabolism of Bendamustine can be decreased when combined with Dapagliflozin.
Pilocarpine Pilocarpine The metabolism of Dapagliflozin can be decreased when combined with Pilocarpine.
Flecainide Flecainide The metabolism of Flecainide can be decreased when combined with Dapagliflozin.
Certolizumab Injection Certolizumab Injection The metabolism of Dapagliflozin can be increased when combined with Certolizumab pegol.
Daptomycin Injection Daptomycin Injection Dapagliflozin may increase the excretion rate of Daptomycin which could result in a lower serum level and potentially a reduction in efficacy.
Praziquantel Praziquantel The metabolism of Praziquantel can be decreased when combined with Dapagliflozin.
Methylnaltrexone Injection Methylnaltrexone Injection Dapagliflozin may increase the excretion rate of Methylnaltrexone which could result in a lower serum level and potentially a reduction in efficacy.
Midazolam Midazolam Dapagliflozin may increase the excretion rate of Midazolam which could result in a lower serum level and potentially a reduction in efficacy.
Naltrexone Injection Naltrexone Injection The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Naltrexone.
Dexrazoxane Injection Dexrazoxane Injection Dapagliflozin may increase the excretion rate of Dexrazoxane which could result in a lower serum level and potentially a reduction in efficacy.
Eltrombopag Eltrombopag The metabolism of Dapagliflozin can be decreased when combined with Eltrombopag.
Milnacipran Milnacipran The risk or severity of hypoglycemia can be increased when Milnacipran is combined with Dapagliflozin.
Plerixafor Injection Plerixafor Injection Dapagliflozin may increase the excretion rate of Plerixafor which could result in a lower serum level and potentially a reduction in efficacy.
Sodium Phosphate Sodium Phosphate Dapagliflozin may increase the nephrotoxic activities of Sodium phosphate, monobasic.
Fesoterodine Fesoterodine Dapagliflozin may increase the excretion rate of Fesoterodine which could result in a lower serum level and potentially a reduction in efficacy.
Betaxolol Betaxolol The therapeutic efficacy of Betaxolol can be increased when used in combination with Dapagliflozin.
Iloperidone Iloperidone The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Iloperidone.
Prasugrel Prasugrel Prasugrel may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Lacosamide Lacosamide The metabolism of Dapagliflozin can be decreased when combined with Lacosamide.
Everolimus Everolimus The metabolism of Everolimus can be decreased when combined with Dapagliflozin.
Dronedarone Dronedarone The metabolism of Dronedarone can be decreased when combined with Dapagliflozin.
Pralatrexate Injection Pralatrexate Injection Dapagliflozin may increase the excretion rate of Pralatrexate which could result in a lower serum level and potentially a reduction in efficacy.
Palonosetron Injection Palonosetron Injection Dapagliflozin may increase the excretion rate of Palonosetron which could result in a lower serum level and potentially a reduction in efficacy.
Telavancin Injection Telavancin Injection Dapagliflozin may increase the excretion rate of Telavancin which could result in a lower serum level and potentially a reduction in efficacy.
Tapentadol Tapentadol The metabolism of Dapagliflozin can be decreased when combined with Tapentadol.
Topotecan Topotecan Dapagliflozin may increase the excretion rate of Topotecan which could result in a lower serum level and potentially a reduction in efficacy.
Golimumab Injection Golimumab Injection The metabolism of Dapagliflozin can be increased when combined with Golimumab.
Pazopanib Pazopanib The metabolism of Pazopanib can be decreased when combined with Dapagliflozin.
Asenapine Asenapine The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Asenapine.
Pitavastatin Pitavastatin The metabolism of Pitavastatin can be decreased when combined with Dapagliflozin.
Albendazole Albendazole The metabolism of Albendazole can be decreased when combined with Dapagliflozin.
Levonorgestrel Levonorgestrel The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Levonorgestrel.
Oxymorphone Oxymorphone The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Oxymorphone.
Liraglutide Injection Liraglutide Injection Dapagliflozin may increase the hypoglycemic activities of Liraglutide.
Tocilizumab Injection Tocilizumab Injection The metabolism of Dapagliflozin can be increased when combined with Tocilizumab.
Dalfampridine Dalfampridine Dapagliflozin may increase the excretion rate of Dalfampridine which could result in a lower serum level and potentially a reduction in efficacy.
Lurasidone Lurasidone The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Lurasidone.
Acetaminophen Injection Acetaminophen Injection The metabolism of Acetaminophen can be decreased when combined with Dapagliflozin.
Vilazodone Vilazodone The metabolism of Dapagliflozin can be decreased when combined with Vilazodone.
Ipilimumab Injection Ipilimumab Injection Dapagliflozin may increase the excretion rate of Ipilimumab which could result in a lower serum level and potentially a reduction in efficacy.
Denileukin Diftitox Injection Denileukin Diftitox Injection Dapagliflozin may increase the excretion rate of Aldesleukin which could result in a lower serum level and potentially a reduction in efficacy.
Terbutaline Injection Terbutaline Injection Dapagliflozin may increase the excretion rate of Terbutaline which could result in a lower serum level and potentially a reduction in efficacy.
Azilsartan Azilsartan The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Azilsartan medoxomil.
Roflumilast Roflumilast Dapagliflozin may increase the excretion rate of Roflumilast which could result in a lower serum level and potentially a reduction in efficacy.
Linagliptin Linagliptin Dapagliflozin may increase the hypoglycemic activities of Linagliptin.
Rilpivirine Rilpivirine The metabolism of Rilpivirine can be decreased when combined with Dapagliflozin.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Dapagliflozin can be decreased when combined with Cyclophosphamide.
Abiraterone Abiraterone The serum concentration of Dapagliflozin can be increased when it is combined with Abiraterone.
Triptorelin Injection Triptorelin Injection The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Triptorelin.
Rivaroxaban Rivaroxaban Dapagliflozin may increase the excretion rate of Rivaroxaban which could result in a lower serum level and potentially a reduction in efficacy.
Ticagrelor Ticagrelor The metabolism of Dapagliflozin can be decreased when combined with Ticagrelor.
Ruxolitinib Ruxolitinib Dapagliflozin may increase the excretion rate of Ruxolitinib which could result in a lower serum level and potentially a reduction in efficacy.
Clobazam Clobazam The metabolism of Dapagliflozin can be decreased when combined with Clobazam.
Vemurafenib Vemurafenib The serum concentration of Dapagliflozin can be increased when it is combined with Vemurafenib.
Vismodegib Vismodegib The metabolism of Dapagliflozin can be decreased when combined with Vismodegib.
Deferiprone Deferiprone Dapagliflozin may increase the excretion rate of Deferiprone which could result in a lower serum level and potentially a reduction in efficacy.
Axitinib Axitinib The metabolism of Axitinib can be decreased when combined with Dapagliflozin.
Naloxone Injection Naloxone Injection Dapagliflozin may increase the excretion rate of Naloxone which could result in a lower serum level and potentially a reduction in efficacy.
Ambrisentan Ambrisentan Dapagliflozin may increase the hypotensive activities of Ambrisentan.
Fondaparinux Injection Fondaparinux Injection Dapagliflozin may increase the excretion rate of Fondaparinux which could result in a lower serum level and potentially a reduction in efficacy.
Iloprost Iloprost The risk or severity of adverse effects can be increased when Iloprost is combined with Dapagliflozin.
Enzalutamide Enzalutamide The metabolism of Dapagliflozin can be increased when combined with Enzalutamide.
Mirabegron Mirabegron The metabolism of Dapagliflozin can be decreased when combined with Mirabegron.
Regorafenib Regorafenib The metabolism of Dapagliflozin can be decreased when combined with Regorafenib.
Corticotropin, Repository Injection Corticotropin, Repository Injection The risk or severity of hyperglycemia can be increased when Corticotropin is combined with Dapagliflozin.
Linaclotide Linaclotide The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Linaclotide.
Teriflunomide Teriflunomide The serum concentration of Dapagliflozin can be decreased when it is combined with Teriflunomide.
Lorcaserin Lorcaserin Dapagliflozin may increase the hypoglycemic activities of Mecasermin.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Dapagliflozin.
Teduglutide Injection Teduglutide Injection Dapagliflozin may increase the excretion rate of Teduglutide which could result in a lower serum level and potentially a reduction in efficacy.
Alogliptin Alogliptin Dapagliflozin may increase the hypoglycemic activities of Alogliptin.
Ponatinib Ponatinib The metabolism of Ponatinib can be decreased when combined with Dapagliflozin.
Pomalidomide Pomalidomide The metabolism of Pomalidomide can be decreased when combined with Dapagliflozin.
Apixaban Apixaban The metabolism of Apixaban can be decreased when combined with Dapagliflozin.
Canagliflozin Canagliflozin Dapagliflozin may increase the hypoglycemic activities of Canagliflozin.
Methazolamide Methazolamide The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Methazolamide.
Dabrafenib Dabrafenib The metabolism of Dapagliflozin can be increased when combined with Dabrafenib.
Ospemifene Ospemifene The metabolism of Dapagliflozin can be decreased when combined with Ospemifene.
Trametinib Trametinib Dapagliflozin may increase the excretion rate of Trametinib which could result in a lower serum level and potentially a reduction in efficacy.
Levomilnacipran Levomilnacipran The risk or severity of hypoglycemia can be increased when Dapagliflozin is combined with Levomilnacipran.
Ertapenem Injection Ertapenem Injection Dapagliflozin may increase the excretion rate of Ertapenem which could result in a lower serum level and potentially a reduction in efficacy.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Dapagliflozin.
Perampanel Perampanel The metabolism of Perampanel can be decreased when combined with Dapagliflozin.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Dapagliflozin.
Avanafil Avanafil The risk or severity of hypotension can be increased when Avanafil is combined with Dapagliflozin.
Ketorolac Injection Ketorolac Injection The metabolism of Dapagliflozin can be decreased when combined with Ketorolac.
Obinutuzumab Injection Obinutuzumab Injection The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Obinutuzumab.
Simeprevir Simeprevir The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Simeprevir.
Sofosbuvir Sofosbuvir Dapagliflozin may increase the excretion rate of Sofosbuvir which could result in a lower serum level and potentially a reduction in efficacy.
Apremilast Apremilast The metabolism of Dapagliflozin can be increased when combined with Apremilast.
Droxidopa Droxidopa The risk or severity of Cardiac Arrhythmia can be increased when Droxidopa is combined with Dapagliflozin.
Ceritinib Ceritinib The metabolism of Dapagliflozin can be decreased when combined with Ceritinib.
Siltuximab Injection Siltuximab Injection The metabolism of Dapagliflozin can be increased when combined with Siltuximab.
Albiglutide Injection Albiglutide Injection Dapagliflozin may increase the hypoglycemic activities of Albiglutide.
Belinostat Injection Belinostat Injection The metabolism of Dapagliflozin can be increased when combined with Belinostat.
Testosterone Injection Testosterone Injection Testosterone may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Oritavancin Injection Oritavancin Injection The metabolism of Dapagliflozin can be decreased when combined with Oritavancin.
Empagliflozin Empagliflozin Dapagliflozin may increase the diuretic activities of Empagliflozin.
Hydrocodone Hydrocodone The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Hydrocodone.
Dulaglutide Injection Dulaglutide Injection Dapagliflozin may increase the hypoglycemic activities of Dulaglutide.
Edoxaban Edoxaban Dapagliflozin may increase the excretion rate of Edoxaban which could result in a lower serum level and potentially a reduction in efficacy.
Peginterferon Beta-1a Injection Peginterferon Beta-1a Injection The metabolism of Dapagliflozin can be decreased when combined with Peginterferon beta-1a.
Methamphetamine Methamphetamine Metamfetamine may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Tasimelteon Tasimelteon The metabolism of Tasimelteon can be decreased when combined with Dapagliflozin.
Riociguat Riociguat The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Riociguat.
Lanreotide Injection Lanreotide Injection The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Lanreotide.
Pirfenidone Pirfenidone The metabolism of Dapagliflozin can be decreased when combined with Pirfenidone.
Secukinumab Injection Secukinumab Injection The metabolism of Dapagliflozin can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection Dapagliflozin may increase the hypotensive activities of Risperidone.
Insulin Human Inhalation Insulin Human Inhalation Dapagliflozin may increase the hypoglycemic activities of Insulin human.
Lenvatinib Lenvatinib The metabolism of Dapagliflozin can be decreased when combined with Lenvatinib.
Naloxegol Naloxegol The metabolism of Dapagliflozin can be decreased when combined with Naloxegol.
Panobinostat Panobinostat The metabolism of Dapagliflozin can be decreased when combined with Panobinostat.
Dinutuximab Injection Dinutuximab Injection The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Dinutuximab.
Haloperidol Injection Haloperidol Injection The serum concentration of Haloperidol can be increased when it is combined with Dapagliflozin.
Amiloride Amiloride The risk or severity of adverse effects can be increased when Amiloride is combined with Dapagliflozin.
Macitentan Macitentan Dapagliflozin may increase the excretion rate of Macitentan which could result in a lower serum level and potentially a reduction in efficacy.
Rolapitant Rolapitant The metabolism of Dapagliflozin can be decreased when combined with Rolapitant.
Prednisolone Prednisolone The risk or severity of hyperglycemia can be increased when Prednisolone is combined with Dapagliflozin.
Brexpiprazole Brexpiprazole The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Brexpiprazole.
Ziprasidone Injection Ziprasidone Injection The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Ziprasidone.
Cariprazine Cariprazine The metabolism of Dapagliflozin can be decreased when combined with Cariprazine.
Penicillin G Procaine Injection Penicillin G Procaine Injection Dapagliflozin may increase the excretion rate of Procaine benzylpenicillin which could result in a lower serum level and potentially a reduction in efficacy.
Eluxadoline Eluxadoline The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Eluxadoline.
Insulin Degludec (rDNA Origin) Injection Insulin Degludec (rDNA Origin) Injection Dapagliflozin may increase the hypoglycemic activities of Insulin degludec.
Trabectedin Injection Trabectedin Injection The metabolism of Dapagliflozin can be decreased when combined with Trabectedin.
Osimertinib Osimertinib The serum concentration of Dapagliflozin can be decreased when it is combined with Osimertinib.
Ixazomib Ixazomib Dapagliflozin may increase the excretion rate of Ixazomib which could result in a lower serum level and potentially a reduction in efficacy.
Lesinurad Lesinurad Dapagliflozin may increase the excretion rate of Lesinurad which could result in a lower serum level and potentially a reduction in efficacy.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection The risk or severity of adverse effects can be increased when Amphotericin B is combined with Dapagliflozin.
Dexamethasone Injection Dexamethasone Injection The risk or severity of hyperglycemia can be increased when Dexamethasone is combined with Dapagliflozin.
Brivaracetam Injection Brivaracetam Injection Brivaracetam may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Cobicistat Cobicistat The metabolism of Dapagliflozin can be decreased when combined with Cobicistat.
Selexipag Selexipag Dapagliflozin may increase the hypotensive activities of Selexipag.
Obeticholic Acid Obeticholic Acid The metabolism of Dapagliflozin can be decreased when combined with Obeticholic acid.
Diphenhydramine Injection Diphenhydramine Injection The metabolism of Dapagliflozin can be decreased when combined with Diphenhydramine.
Furosemide Injection Furosemide Injection The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Furosemide.
Rucaparib Rucaparib The metabolism of Dapagliflozin can be decreased when combined with Rucaparib.
Lixisenatide Injection Lixisenatide Injection Dapagliflozin may increase the hypoglycemic activities of Lixisenatide.
Doxepin (Insomnia) Doxepin (Insomnia) The metabolism of Dapagliflozin can be decreased when combined with Doxepin.
Plecanatide Plecanatide The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Plecanatide.
Deutetrabenazine Deutetrabenazine Dapagliflozin may increase the excretion rate of Deutetrabenazine which could result in a lower serum level and potentially a reduction in efficacy.
Valbenazine Valbenazine Dapagliflozin may increase the excretion rate of Valbenazine which could result in a lower serum level and potentially a reduction in efficacy.
Deflazacort Deflazacort The risk or severity of hyperglycemia can be increased when Deflazacort is combined with Dapagliflozin.
Safinamide Safinamide Safinamide may increase the orthostatic hypotensive activities of Dapagliflozin.
Naldemedine Naldemedine Dapagliflozin may increase the excretion rate of Naldemedine which could result in a lower serum level and potentially a reduction in efficacy.
Midostaurin Midostaurin The metabolism of Dapagliflozin can be decreased when combined with Midostaurin.
Enasidenib Enasidenib The metabolism of Dapagliflozin can be decreased when combined with Enasidenib.
Benznidazole Benznidazole Dapagliflozin may increase the excretion rate of Benznidazole which could result in a lower serum level and potentially a reduction in efficacy.
Delafloxacin Delafloxacin The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Delafloxacin.
Letermovir Letermovir The metabolism of Letermovir can be decreased when combined with Dapagliflozin.
Semaglutide Injection Semaglutide Injection Dapagliflozin may increase the hypoglycemic activities of Semaglutide.
Tetrabenazine Tetrabenazine The metabolism of Dapagliflozin can be decreased when combined with Tetrabenazine.
Ertugliflozin Ertugliflozin The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Ertugliflozin.
Buprenorphine Injection Buprenorphine Injection The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Buprenorphine.
Apalutamide Apalutamide Apalutamide may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Fostamatinib Fostamatinib The risk or severity of hypotension can be increased when Fostamatinib is combined with Dapagliflozin.
Avatrombopag Avatrombopag The metabolism of Dapagliflozin can be increased when combined with Avatrombopag.
Baricitinib Baricitinib Dapagliflozin may increase the excretion rate of Baricitinib which could result in a lower serum level and potentially a reduction in efficacy.
Lofexidine Lofexidine The metabolism of Lofexidine can be decreased when combined with Dapagliflozin.
Plazomicin Injection Plazomicin Injection Dapagliflozin may increase the excretion rate of Plazomicin which could result in a lower serum level and potentially a reduction in efficacy.
Eliglustat Eliglustat The metabolism of Dapagliflozin can be decreased when combined with Eliglustat.
Encorafenib Encorafenib The metabolism of Encorafenib can be decreased when combined with Dapagliflozin.
Binimetinib Binimetinib The metabolism of Binimetinib can be decreased when combined with Dapagliflozin.
Elagolix Elagolix The metabolism of Elagolix can be decreased when combined with Dapagliflozin.
Tafenoquine Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Dapagliflozin.
Cannabidiol Cannabidiol The metabolism of Cannabidiol can be decreased when combined with Dapagliflozin.
Dacomitinib Dacomitinib The metabolism of Dapagliflozin can be decreased when combined with Dacomitinib.
Stiripentol Stiripentol The metabolism of Dapagliflozin can be decreased when combined with Stiripentol.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The risk or severity of adverse effects can be increased when Paclitaxel is combined with Dapagliflozin.
Rifamycin Rifamycin The metabolism of Dapagliflozin can be decreased when combined with Rifamycin.
Prucalopride Prucalopride The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Prucalopride.
Magnesium Citrate Magnesium Citrate The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Magnesium citrate.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Dapagliflozin can be increased when combined with Emapalumab.
Siponimod Siponimod The metabolism of Siponimod can be decreased when combined with Dapagliflozin.
Acyclovir Ophthalmic Acyclovir Ophthalmic The metabolism of Acyclovir can be decreased when combined with Dapagliflozin.
Erdafitinib Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Dapagliflozin.
Alpelisib Alpelisib The serum concentration of Dapagliflozin can be decreased when it is combined with Alpelisib.
Solriamfetol Solriamfetol Dapagliflozin may increase the excretion rate of Solriamfetol which could result in a lower serum level and potentially a reduction in efficacy.
Triclabendazole Triclabendazole The metabolism of Dapagliflozin can be decreased when combined with Triclabendazole.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Dapagliflozin.
Pitolisant Pitolisant The serum concentration of Dapagliflozin can be decreased when it is combined with Pitolisant.
Fedratinib Fedratinib The metabolism of Dapagliflozin can be decreased when combined with Fedratinib.
Phenytoin Injection Phenytoin Injection The metabolism of Dapagliflozin can be decreased when combined with Phenytoin.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Dapagliflozin can be decreased when combined with Fosphenytoin.
Voxelotor Voxelotor The metabolism of Voxelotor can be decreased when combined with Dapagliflozin.
Avapritinib Avapritinib The metabolism of Avapritinib can be decreased when combined with Dapagliflozin.
Cenobamate Cenobamate The serum concentration of Dapagliflozin can be decreased when it is combined with Cenobamate.
Teprotumumab-trbw Injection Teprotumumab-trbw Injection The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Teprotumumab.
Selumetinib Selumetinib The metabolism of Selumetinib can be decreased when combined with Dapagliflozin.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Dapagliflozin.
Capmatinib Capmatinib The metabolism of Dapagliflozin can be decreased when combined with Capmatinib.
Fenfluramine Fenfluramine The metabolism of Dapagliflozin can be decreased when combined with Fenfluramine.
Octreotide Octreotide The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Octreotide.
Pralsetinib Pralsetinib The metabolism of Dapagliflozin can be decreased when combined with Pralsetinib.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Dapagliflozin can be decreased when it is combined with Satralizumab.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Drospirenone.
Viloxazine Viloxazine Dapagliflozin may increase the excretion rate of Viloxazine which could result in a lower serum level and potentially a reduction in efficacy.
Theophylline Theophylline The metabolism of Theophylline can be decreased when combined with Dapagliflozin.
Indomethacin Indomethacin The metabolism of Dapagliflozin can be decreased when combined with Indomethacin.
Mefenamic Acid Mefenamic Acid The metabolism of Dapagliflozin can be decreased when combined with Mefenamic acid.
Naproxen Naproxen The metabolism of Naproxen can be decreased when combined with Dapagliflozin.
Trazodone Trazodone The metabolism of Dapagliflozin can be decreased when combined with Trazodone.
Isotretinoin Isotretinoin Dapagliflozin may increase the excretion rate of Isotretinoin which could result in a lower serum level and potentially a reduction in efficacy.
Sucralfate Sucralfate Dapagliflozin may increase the excretion rate of Sucralfate which could result in a lower serum level and potentially a reduction in efficacy.
Hydroxyurea Hydroxyurea The metabolism of Dapagliflozin can be decreased when combined with Hydroxyurea.
Floxuridine Floxuridine The metabolism of Dapagliflozin can be decreased when combined with Floxuridine.
Phenobarbital Phenobarbital The metabolism of Dapagliflozin can be decreased when combined with Phenobarbital.
Metaxalone Metaxalone Dapagliflozin may increase the excretion rate of Metaxalone which could result in a lower serum level and potentially a reduction in efficacy.
Methotrexate Injection Methotrexate Injection Dapagliflozin may increase the excretion rate of Methotrexate which could result in a lower serum level and potentially a reduction in efficacy.
Levorphanol Levorphanol The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Levorphanol.
Primidone Primidone The metabolism of Dapagliflozin can be increased when combined with Primidone.
Methsuximide Methsuximide The risk or severity of hypoglycemia can be increased when Methsuximide is combined with Dapagliflozin.
Chlorpromazine Chlorpromazine The metabolism of Chlorpromazine can be decreased when combined with Dapagliflozin.
Diazepam Diazepam Diazepam may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Oxazepam Oxazepam Dapagliflozin may increase the excretion rate of Oxazepam which could result in a lower serum level and potentially a reduction in efficacy.
Flurazepam Flurazepam Dapagliflozin may increase the excretion rate of Flurazepam which could result in a lower serum level and potentially a reduction in efficacy.
Clorazepate Clorazepate Dapagliflozin may increase the excretion rate of Clorazepic acid which could result in a lower serum level and potentially a reduction in efficacy.
Lorazepam Lorazepam Dapagliflozin may increase the excretion rate of Lorazepam which could result in a lower serum level and potentially a reduction in efficacy.
Phenoxybenzamine Phenoxybenzamine The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Phenoxybenzamine.
Carmustine Carmustine The metabolism of Carmustine can be decreased when combined with Dapagliflozin.
Amantadine Amantadine Dapagliflozin may increase the excretion rate of Amantadine which could result in a lower serum level and potentially a reduction in efficacy.
Codeine Codeine The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Codeine.
Bromocriptine Bromocriptine Dapagliflozin may increase the hypoglycemic activities of Bromocriptine.
Tranylcypromine Tranylcypromine The metabolism of Dapagliflozin can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine Phenelzine may increase the orthostatic hypotensive activities of Dapagliflozin.
Procarbazine Procarbazine Procarbazine may increase the orthostatic hypotensive activities of Dapagliflozin.
Tetracycline Tetracycline Dapagliflozin may increase the excretion rate of Tetracycline which could result in a lower serum level and potentially a reduction in efficacy.
Prochlorperazine Prochlorperazine The metabolism of Dapagliflozin can be decreased when combined with Prochlorperazine.
Thioridazine Thioridazine The metabolism of Dapagliflozin can be decreased when combined with Thioridazine.
Trifluoperazine Trifluoperazine The metabolism of Trifluoperazine can be decreased when combined with Dapagliflozin.
Bleomycin Bleomycin Dapagliflozin may increase the excretion rate of Bleomycin which could result in a lower serum level and potentially a reduction in efficacy.
Dapsone Dapsone The metabolism of Dapagliflozin can be decreased when combined with Dapsone.
Sulfadiazine Sulfadiazine The metabolism of Dapagliflozin can be decreased when combined with Sulfadiazine.
Oxycodone Oxycodone The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Oxycodone.
Methadone Methadone The metabolism of Dapagliflozin can be decreased when combined with Methadone.
Oxybutynin Oxybutynin The metabolism of Dapagliflozin can be decreased when combined with Oxybutynin.
Benztropine Benztropine Benzatropine may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Maprotiline Maprotiline The metabolism of Maprotiline can be decreased when combined with Dapagliflozin.
Ibuprofen Ibuprofen Ibuprofen may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Orphenadrine Orphenadrine The metabolism of Dapagliflozin can be decreased when combined with Orphenadrine.
Perphenazine Perphenazine The metabolism of Perphenazine can be decreased when combined with Dapagliflozin.
Azathioprine Azathioprine The metabolism of Azathioprine can be decreased when combined with Dapagliflozin.
Fluphenazine Fluphenazine The metabolism of Dapagliflozin can be decreased when combined with Fluphenazine.
Phentermine Phentermine The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Phentermine.
Methylphenidate Methylphenidate Dapagliflozin may increase the excretion rate of Methylphenidate which could result in a lower serum level and potentially a reduction in efficacy.
Amoxapine Amoxapine The metabolism of Dapagliflozin can be decreased when combined with Amoxapine.
Sulfasalazine Sulfasalazine Sulfasalazine may increase the hypoglycemic activities of Dapagliflozin.
Hydrocortisone Hydrocortisone The risk or severity of hyperglycemia can be increased when Hydrocortisone is combined with Dapagliflozin.
Doxorubicin Doxorubicin The metabolism of Dapagliflozin can be decreased when combined with Doxorubicin.
Phenazopyridine Phenazopyridine Dapagliflozin may increase the excretion rate of Phenazopyridine which could result in a lower serum level and potentially a reduction in efficacy.
Carbamazepine Carbamazepine The metabolism of Dapagliflozin can be increased when combined with Carbamazepine.
Methyldopa Methyldopa Dapagliflozin may increase the excretion rate of Methyldopa which could result in a lower serum level and potentially a reduction in efficacy.
Clonidine Clonidine The metabolism of Clonidine can be decreased when combined with Dapagliflozin.
Prazosin Prazosin The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Prazosin.
Hydralazine Hydralazine Dapagliflozin may increase the excretion rate of Hydralazine which could result in a lower serum level and potentially a reduction in efficacy.
Cimetidine Cimetidine The metabolism of Dapagliflozin can be decreased when combined with Cimetidine.
Warfarin Warfarin The metabolism of Warfarin can be decreased when combined with Dapagliflozin.
Clonazepam Clonazepam Dapagliflozin may increase the excretion rate of Clonazepam which could result in a lower serum level and potentially a reduction in efficacy.
Loperamide Loperamide The risk or severity of hypoglycemia can be increased when Loperamide is combined with Dapagliflozin.
Promethazine Promethazine The metabolism of Dapagliflozin can be decreased when combined with Promethazine.
Meclofenamate Meclofenamate Dapagliflozin may increase the excretion rate of Meclofenamic acid which could result in a lower serum level and potentially a reduction in efficacy.
Nitrofurantoin Nitrofurantoin Dapagliflozin may increase the excretion rate of Nitrofurantoin which could result in a lower serum level and potentially a reduction in efficacy.
Griseofulvin Griseofulvin The metabolism of Dapagliflozin can be increased when combined with Griseofulvin.
Digoxin Digoxin Dapagliflozin may increase the excretion rate of Digoxin which could result in a lower serum level and potentially a reduction in efficacy.
Chloroquine Chloroquine The metabolism of Dapagliflozin can be decreased when combined with Chloroquine.
Quinine Quinine The metabolism of Dapagliflozin can be decreased when combined with Quinine.
Ethosuximide Ethosuximide The risk or severity of hypoglycemia can be increased when Ethosuximide is combined with Dapagliflozin.
Triamterene Triamterene The metabolism of Triamterene can be decreased when combined with Dapagliflozin.
Lactulose Lactulose The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Lactulose.
Sulfinpyrazone Sulfinpyrazone The metabolism of Dapagliflozin can be decreased when combined with Sulfinpyrazone.
Chlorothiazide Chlorothiazide The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Chlorothiazide.
Chlorthalidone Chlorthalidone The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Chlorthalidone.
Metolazone Metolazone The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Metolazone.
Secobarbital Secobarbital Secobarbital may increase the hypotensive activities of Dapagliflozin.
Desipramine Desipramine The metabolism of Desipramine can be decreased when combined with Dapagliflozin.
Amitriptyline Amitriptyline The metabolism of Dapagliflozin can be decreased when combined with Amitriptyline.
Imipramine Imipramine The metabolism of Imipramine can be decreased when combined with Dapagliflozin.
Probenecid Probenecid The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Probenecid.
Quinidine Quinidine The metabolism of Dapagliflozin can be decreased when combined with Quinidine.
Procainamide Procainamide The metabolism of Procainamide can be decreased when combined with Dapagliflozin.
Isoniazid Isoniazid The metabolism of Dapagliflozin can be decreased when combined with Isoniazid.
Pyrazinamide Pyrazinamide Dapagliflozin may increase the excretion rate of Pyrazinamide which could result in a lower serum level and potentially a reduction in efficacy.
Rifampin Rifampin The metabolism of Dapagliflozin can be increased when combined with Rifampicin.
Disopyramide Disopyramide Dapagliflozin may increase the hypoglycemic activities of Disopyramide.
Valproic Acid Valproic Acid The metabolism of Dapagliflozin can be decreased when combined with Valproic acid.
Tamoxifen Tamoxifen The metabolism of Dapagliflozin can be decreased when combined with Tamoxifen.
Butabarbital Butabarbital Dapagliflozin may increase the excretion rate of Butabarbital which could result in a lower serum level and potentially a reduction in efficacy.
Levothyroxine Levothyroxine The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Levothyroxine.
Liothyronine Liothyronine The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Liothyronine.
Methimazole Methimazole The metabolism of Dapagliflozin can be decreased when combined with Methimazole.
Chlorpropamide Chlorpropamide Dapagliflozin may increase the hypoglycemic activities of Chlorpropamide.
Tolbutamide Tolbutamide Dapagliflozin may increase the hypoglycemic activities of Tolbutamide.
Tolazamide Tolazamide Dapagliflozin may increase the hypoglycemic activities of Tolazamide.
Dextromethorphan Dextromethorphan The metabolism of Dapagliflozin can be decreased when combined with Dextromethorphan.
Cyclobenzaprine Cyclobenzaprine The metabolism of Cyclobenzaprine can be decreased when combined with Dapagliflozin.
Niacin Niacin The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Niacin.
Baclofen Baclofen The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Baclofen.
Clemastine Clemastine The metabolism of Dapagliflozin can be decreased when combined with Clemastine.
Chlorpheniramine Chlorpheniramine The metabolism of Dapagliflozin can be decreased when combined with Chlorpheniramine.
Meclizine Meclizine The metabolism of Dapagliflozin can be decreased when combined with Meclizine.
Ethambutol Ethambutol Dapagliflozin may increase the excretion rate of Ethambutol which could result in a lower serum level and potentially a reduction in efficacy.
Methyclothiazide Methyclothiazide The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Methyclothiazide.
Hydrochlorothiazide Hydrochlorothiazide The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Hydrochlorothiazide.
Chlorzoxazone Chlorzoxazone The metabolism of Chlorzoxazone can be decreased when combined with Dapagliflozin.
Pyridoxine Pyridoxine Dapagliflozin may increase the excretion rate of Pyridoxine which could result in a lower serum level and potentially a reduction in efficacy.
Folic Acid Folic Acid Dapagliflozin may increase the excretion rate of Folic acid which could result in a lower serum level and potentially a reduction in efficacy.
Danazol Danazol The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Danazol.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The therapeutic efficacy of Propranolol can be increased when used in combination with Dapagliflozin.
Minoxidil Minoxidil The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Minoxidil.
Pseudoephedrine Pseudoephedrine The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Pseudoephedrine.
Nortriptyline Nortriptyline The metabolism of Dapagliflozin can be decreased when combined with Nortriptyline.
Spironolactone Spironolactone The risk or severity of adverse effects can be increased when Spironolactone is combined with Dapagliflozin.
Amphotericin B Injection Amphotericin B Injection The risk or severity of adverse effects can be increased when Amphotericin B is combined with Dapagliflozin.
Phytonadione Phytonadione Dapagliflozin may increase the excretion rate of Phylloquinone which could result in a lower serum level and potentially a reduction in efficacy.
Nadolol Nadolol The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Nadolol.
Butorphanol Injection Butorphanol Injection The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Butorphanol.
Nalbuphine Injection Nalbuphine Injection The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Nalbuphine.
Allopurinol Allopurinol Dapagliflozin may increase the excretion rate of Allopurinol which could result in a lower serum level and potentially a reduction in efficacy.
Fluoxymesterone Fluoxymesterone Fluoxymesterone may increase the hypoglycemic activities of Dapagliflozin.
Flavoxate Flavoxate Dapagliflozin may increase the excretion rate of Flavoxate which could result in a lower serum level and potentially a reduction in efficacy.
Papaverine Papaverine The risk or severity of adverse effects can be increased when Papaverine is combined with Dapagliflozin.
Fluorouracil Injection Fluorouracil Injection The metabolism of Fluorouracil can be decreased when combined with Dapagliflozin.
Colchicine Colchicine Dapagliflozin may increase the excretion rate of Colchicine which could result in a lower serum level and potentially a reduction in efficacy.
Cefaclor Cefaclor Dapagliflozin may increase the excretion rate of Cefaclor which could result in a lower serum level and potentially a reduction in efficacy.
Cefadroxil Cefadroxil Dapagliflozin may increase the excretion rate of Cefadroxil which could result in a lower serum level and potentially a reduction in efficacy.
Cephalexin Cephalexin Dapagliflozin may increase the excretion rate of Cephalexin which could result in a lower serum level and potentially a reduction in efficacy.
Dacarbazine Dacarbazine The metabolism of Dacarbazine can be decreased when combined with Dapagliflozin.
Acetazolamide Acetazolamide The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Acetazolamide.
Calcitonin Salmon Injection Calcitonin Salmon Injection Dapagliflozin may increase the excretion rate of Salmon calcitonin which could result in a lower serum level and potentially a reduction in efficacy.
Ketoconazole Ketoconazole The metabolism of Dapagliflozin can be decreased when combined with Ketoconazole.
Pyrantel Pyrantel Dapagliflozin may increase the excretion rate of Pyrantel which could result in a lower serum level and potentially a reduction in efficacy.
Captopril Captopril The risk or severity of renal failure, hypotension, and hyperkalemia can be increased when Captopril is combined with Dapagliflozin.
Dipyridamole Dipyridamole The risk or severity of adverse effects can be increased when Dipyridamole is combined with Dapagliflozin.
Isoxsuprine Isoxsuprine The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Isoxsuprine.
Vinblastine Vinblastine The metabolism of Dapagliflozin can be decreased when combined with Vinblastine.
Ethacrynic Acid Ethacrynic Acid The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Etacrynic acid.
Metoprolol Metoprolol The metabolism of Dapagliflozin can be decreased when combined with Metoprolol.
Hydroxyzine Hydroxyzine The metabolism of Dapagliflozin can be decreased when combined with Hydroxyzine.
Thiothixene Thiothixene The metabolism of Thiothixene can be decreased when combined with Dapagliflozin.
Aspirin Aspirin The risk or severity of hypoglycemia can be increased when Acetylsalicylic acid is combined with Dapagliflozin.
Alprazolam Alprazolam Alprazolam may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Temazepam Temazepam Dapagliflozin may increase the excretion rate of Temazepam which could result in a lower serum level and potentially a reduction in efficacy.
Triazolam Triazolam Dapagliflozin may increase the excretion rate of Triazolam which could result in a lower serum level and potentially a reduction in efficacy.
Dicyclomine Dicyclomine Dapagliflozin may increase the excretion rate of Dicyclomine which could result in a lower serum level and potentially a reduction in efficacy.
Propantheline Propantheline Dapagliflozin may increase the excretion rate of Propantheline which could result in a lower serum level and potentially a reduction in efficacy.
Trimethoprim Trimethoprim Trimethoprim may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Diltiazem Diltiazem The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Dapagliflozin.
Nifedipine Nifedipine The metabolism of Dapagliflozin can be decreased when combined with Nifedipine.
Timolol Timolol The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Timolol.
Verapamil Verapamil The metabolism of Dapagliflozin can be decreased when combined with Verapamil.
Atenolol Atenolol The therapeutic efficacy of Atenolol can be increased when used in combination with Dapagliflozin.
Pindolol Pindolol The therapeutic efficacy of Pindolol can be increased when used in combination with Dapagliflozin.
Cisplatin Injection Cisplatin Injection The metabolism of Dapagliflozin can be decreased when combined with Cisplatin.
Diflunisal Diflunisal The metabolism of Dapagliflozin can be decreased when combined with Diflunisal.
Piroxicam Piroxicam Piroxicam may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Bumetanide Bumetanide The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Bumetanide.
Streptozocin Streptozocin The metabolism of Dapagliflozin can be increased when combined with Streptozocin.
Etoposide Etoposide The metabolism of Etoposide can be decreased when combined with Dapagliflozin.
Glyburide Glyburide The metabolism of Dapagliflozin can be decreased when combined with Glyburide.
Glipizide Glipizide Dapagliflozin may increase the hypoglycemic activities of Glipizide.
Indapamide Indapamide The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Indapamide.
Amoxicillin Amoxicillin Dapagliflozin may increase the excretion rate of Amoxicillin which could result in a lower serum level and potentially a reduction in efficacy.
Nafcillin Injection Nafcillin Injection The metabolism of Dapagliflozin can be increased when combined with Nafcillin.
Oxacillin Injection Oxacillin Injection Dapagliflozin may increase the excretion rate of Oxacillin which could result in a lower serum level and potentially a reduction in efficacy.
Pentoxifylline Pentoxifylline The metabolism of Pentoxifylline can be decreased when combined with Dapagliflozin.
Pentamidine Injection Pentamidine Injection Dapagliflozin may increase the hypoglycemic activities of Pentamidine.
Ceftriaxone Injection Ceftriaxone Injection Dapagliflozin may increase the excretion rate of Ceftriaxone which could result in a lower serum level and potentially a reduction in efficacy.
Labetalol Labetalol The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Labetalol.
Auranofin Auranofin Dapagliflozin may increase the excretion rate of Auranofin which could result in a lower serum level and potentially a reduction in efficacy.
Leuprolide Injection Leuprolide Injection The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Leuprolide.
Gemfibrozil Gemfibrozil The metabolism of Dapagliflozin can be decreased when combined with Gemfibrozil.
Guanabenz Guanabenz The metabolism of Guanabenz can be decreased when combined with Dapagliflozin.
Ceftazidime Injection Ceftazidime Injection Dapagliflozin may increase the excretion rate of Ceftazidime which could result in a lower serum level and potentially a reduction in efficacy.
Ketoprofen Ketoprofen Dapagliflozin may increase the excretion rate of Ketoprofen which could result in a lower serum level and potentially a reduction in efficacy.
Cefotetan Injection Cefotetan Injection Dapagliflozin may increase the excretion rate of Cefotetan which could result in a lower serum level and potentially a reduction in efficacy.
Pimozide Pimozide The metabolism of Pimozide can be decreased when combined with Dapagliflozin.
Enalapril Enalapril The risk or severity of renal failure, hypotension, and hyperkalemia can be increased when Enalapril is combined with Dapagliflozin.
Flurbiprofen Flurbiprofen Flurbiprofen may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Amiodarone Amiodarone The metabolism of Dapagliflozin can be decreased when combined with Amiodarone.
Aztreonam Injection Aztreonam Injection Dapagliflozin may increase the excretion rate of Aztreonam which could result in a lower serum level and potentially a reduction in efficacy.
Buspirone Buspirone Buspirone may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Lovastatin Lovastatin The metabolism of Lovastatin can be decreased when combined with Dapagliflozin.
Ciprofloxacin Ciprofloxacin The metabolism of Dapagliflozin can be decreased when combined with Ciprofloxacin.
Mesalamine Mesalamine Mesalazine may increase the hypoglycemic activities of Dapagliflozin.
Diclofenac Diclofenac The metabolism of Diclofenac can be decreased when combined with Dapagliflozin.
Fluoxetine Fluoxetine The serum concentration of Dapagliflozin can be increased when it is combined with Fluoxetine.
Nimodipine Nimodipine The risk or severity of hypoglycemia can be increased when Nimodipine is combined with Dapagliflozin.
Interferon Alfa-2b Injection Interferon Alfa-2b Injection The metabolism of Dapagliflozin can be decreased when combined with Interferon alfa-2b.
Clozapine Clozapine The metabolism of Dapagliflozin can be decreased when combined with Clozapine.
Estazolam Estazolam Dapagliflozin may increase the excretion rate of Estazolam which could result in a lower serum level and potentially a reduction in efficacy.
Idarubicin Idarubicin The metabolism of Dapagliflozin can be decreased when combined with Idarubicin.
Ofloxacin Ofloxacin The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Ofloxacin.
Didanosine Didanosine Dapagliflozin may increase the excretion rate of Didanosine which could result in a lower serum level and potentially a reduction in efficacy.
Pentostatin Injection Pentostatin Injection Dapagliflozin may increase the excretion rate of Pentostatin which could result in a lower serum level and potentially a reduction in efficacy.
Benazepril Benazepril The risk or severity of hypoglycemia can be increased when Benazepril is combined with Dapagliflozin.
Etodolac Etodolac Etodolac may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Felodipine Felodipine The metabolism of Felodipine can be decreased when combined with Dapagliflozin.
Fosinopril Fosinopril The risk or severity of renal failure, hypotension, and hyperkalemia can be increased when Dapagliflozin is combined with Fosinopril.
Nabumetone Nabumetone The metabolism of Nabumetone can be decreased when combined with Dapagliflozin.
Quinapril Quinapril The risk or severity of renal failure, hypotension, and hyperkalemia can be increased when Dapagliflozin is combined with Quinapril.
Ramipril Ramipril The risk or severity of renal failure, hypotension, and hyperkalemia can be increased when Dapagliflozin is combined with Ramipril.
Simvastatin Simvastatin The metabolism of Dapagliflozin can be decreased when combined with Simvastatin.
Amlodipine Amlodipine The risk or severity of hypoglycemia can be increased when Amlodipine is combined with Dapagliflozin.
Teniposide Injection Teniposide Injection The metabolism of Dapagliflozin can be decreased when combined with Teniposide.
Lisinopril Lisinopril The risk or severity of renal failure, hypotension, and hyperkalemia can be increased when Dapagliflozin is combined with Lisinopril.
Oxaprozin Oxaprozin Dapagliflozin may increase the excretion rate of Oxaprozin which could result in a lower serum level and potentially a reduction in efficacy.
Atovaquone Atovaquone The metabolism of Dapagliflozin can be decreased when combined with Atovaquone.
Sotalol Sotalol The risk or severity of hypoglycemia can be increased when Sotalol is combined with Dapagliflozin.
Bisoprolol Bisoprolol The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Bisoprolol.
Zolpidem Zolpidem The metabolism of Zolpidem can be decreased when combined with Dapagliflozin.
Doxazosin Doxazosin The metabolism of Dapagliflozin can be decreased when combined with Doxazosin.
Terazosin Terazosin The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Terazosin.
Isradipine Isradipine Isradipine may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Omeprazole Omeprazole The metabolism of Dapagliflozin can be increased when combined with Omeprazole.
Cisapride Cisapride The metabolism of Dapagliflozin can be decreased when combined with Cisapride.
Fluvastatin Fluvastatin The metabolism of Dapagliflozin can be decreased when combined with Fluvastatin.
Venlafaxine Venlafaxine The metabolism of Dapagliflozin can be decreased when combined with Venlafaxine.
Fluvoxamine Fluvoxamine The metabolism of Dapagliflozin can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone The risk or severity of hypoglycemia can be increased when Nefazodone is combined with Dapagliflozin.
Lamotrigine Lamotrigine Lamotrigine may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Losartan Losartan The metabolism of Dapagliflozin can be decreased when combined with Losartan.
Valacyclovir Valacyclovir Dapagliflozin may increase the excretion rate of Valaciclovir which could result in a lower serum level and potentially a reduction in efficacy.
Tramadol Tramadol Tramadol may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Vinorelbine Injection Vinorelbine Injection The metabolism of Dapagliflozin can be decreased when combined with Vinorelbine.
Carboplatin Injection Carboplatin Injection Dapagliflozin may increase the excretion rate of Carboplatin which could result in a lower serum level and potentially a reduction in efficacy.
Moexipril Moexipril The risk or severity of renal failure, hypotension, and hyperkalemia can be increased when Dapagliflozin is combined with Moexipril.
Lansoprazole Lansoprazole The metabolism of Dapagliflozin can be decreased when combined with Lansoprazole.
Ifosfamide Injection Ifosfamide Injection The metabolism of Dapagliflozin can be decreased when combined with Ifosfamide.
Nicardipine Nicardipine The metabolism of Dapagliflozin can be decreased when combined with Nicardipine.
Bupropion Bupropion The metabolism of Dapagliflozin can be decreased when combined with Bupropion.
Ticlopidine Ticlopidine The metabolism of Dapagliflozin can be decreased when combined with Ticlopidine.
Saquinavir Saquinavir The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Saquinavir.
Nisoldipine Nisoldipine Nisoldipine may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Lamivudine Lamivudine Dapagliflozin may increase the excretion rate of Lamivudine which could result in a lower serum level and potentially a reduction in efficacy.
Riluzole Riluzole The metabolism of Riluzole can be decreased when combined with Dapagliflozin.
Amifostine Injection Amifostine Injection The risk or severity of adverse effects can be increased when Amifostine is combined with Dapagliflozin.
Acarbose Acarbose Dapagliflozin may increase the hypoglycemic activities of Acarbose.
Glimepiride Glimepiride Dapagliflozin may increase the hypoglycemic activities of Glimepiride.
Gemcitabine Injection Gemcitabine Injection Dapagliflozin may increase the excretion rate of Gemcitabine which could result in a lower serum level and potentially a reduction in efficacy.
Indinavir Indinavir The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Indinavir.
Ritonavir Ritonavir The serum concentration of Dapagliflozin can be increased when it is combined with Ritonavir.
Cidofovir Injection Cidofovir Injection Dapagliflozin may increase the excretion rate of Cidofovir which could result in a lower serum level and potentially a reduction in efficacy.
Meropenem Injection Meropenem Injection Dapagliflozin may increase the excretion rate of Meropenem which could result in a lower serum level and potentially a reduction in efficacy.
Clomipramine Clomipramine The metabolism of Clomipramine can be decreased when combined with Dapagliflozin.
Zafirlukast Zafirlukast The metabolism of Dapagliflozin can be decreased when combined with Zafirlukast.
Fosfomycin Fosfomycin Dapagliflozin may increase the excretion rate of Fosfomycin which could result in a lower serum level and potentially a reduction in efficacy.
Mirtazapine Mirtazapine The metabolism of Mirtazapine can be decreased when combined with Dapagliflozin.
Trandolapril Trandolapril The risk or severity of renal failure, hypotension, and hyperkalemia can be increased when Dapagliflozin is combined with Trandolapril.
Topiramate Topiramate Dapagliflozin may increase the excretion rate of Topiramate which could result in a lower serum level and potentially a reduction in efficacy.
Zileuton Zileuton The metabolism of Zileuton can be decreased when combined with Dapagliflozin.
Valsartan Valsartan The metabolism of Dapagliflozin can be decreased when combined with Valsartan.
Insulin Lispro Injection Insulin Lispro Injection Dapagliflozin may increase the hypoglycemic activities of Insulin lispro.
Pramipexole Pramipexole Pramipexole may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Donepezil Donepezil The metabolism of Dapagliflozin can be decreased when combined with Donepezil.
Nelfinavir Nelfinavir The metabolism of Dapagliflozin can be decreased when combined with Nelfinavir.
Azithromycin Azithromycin The metabolism of Dapagliflozin can be decreased when combined with Azithromycin.
Carvedilol Carvedilol The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Carvedilol.
Nilutamide Nilutamide The metabolism of Dapagliflozin can be decreased when combined with Nilutamide.
Flutamide Flutamide The metabolism of Flutamide can be decreased when combined with Dapagliflozin.
Selegiline Selegiline Selegiline may increase the orthostatic hypotensive activities of Dapagliflozin.
Bicalutamide Bicalutamide The metabolism of Dapagliflozin can be decreased when combined with Bicalutamide.
Sertraline Sertraline The metabolism of Dapagliflozin can be decreased when combined with Sertraline.
Propafenone Propafenone The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Propafenone.
Letrozole Letrozole The metabolism of Dapagliflozin can be decreased when combined with Letrozole.
Irbesartan Irbesartan The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Irbesartan.
Tamsulosin Tamsulosin The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Tamsulosin.
Ropinirole Ropinirole The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Ropinirole.
Quetiapine Quetiapine The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Quetiapine.
Cetirizine Cetirizine Dapagliflozin may increase the excretion rate of Cetirizine which could result in a lower serum level and potentially a reduction in efficacy.
Paroxetine Paroxetine The metabolism of Dapagliflozin can be decreased when combined with Paroxetine.
Tolcapone Tolcapone The metabolism of Dapagliflozin can be decreased when combined with Tolcapone.
Citalopram Citalopram The metabolism of Dapagliflozin can be decreased when combined with Citalopram.
Capecitabine Capecitabine The metabolism of Dapagliflozin can be decreased when combined with Capecitabine.
Efavirenz Efavirenz The metabolism of Dapagliflozin can be decreased when combined with Efavirenz.
Abacavir Abacavir Dapagliflozin may increase the excretion rate of Abacavir which could result in a lower serum level and potentially a reduction in efficacy.
Sildenafil Sildenafil The metabolism of Dapagliflozin can be decreased when combined with Sildenafil.
Pioglitazone Pioglitazone Dapagliflozin may increase the hypoglycemic activities of Pioglitazone.
Celecoxib Celecoxib The metabolism of Dapagliflozin can be decreased when combined with Celecoxib.
Rosiglitazone Rosiglitazone The metabolism of Dapagliflozin can be decreased when combined with Rosiglitazone.
Tolterodine Tolterodine Tolterodine may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Thalidomide Thalidomide The risk or severity of adverse effects can be increased when Thalidomide is combined with Dapagliflozin.
Oseltamivir Oseltamivir Dapagliflozin may increase the excretion rate of Oseltamivir which could result in a lower serum level and potentially a reduction in efficacy.
Balsalazide Balsalazide Balsalazide may increase the hypoglycemic activities of Dapagliflozin.
Nateglinide Nateglinide Dapagliflozin may increase the hypoglycemic activities of Nateglinide.
Galantamine Galantamine The metabolism of Dapagliflozin can be decreased when combined with Galantamine.
Rabeprazole Rabeprazole The metabolism of Dapagliflozin can be decreased when combined with Rabeprazole.
Terbinafine Terbinafine The metabolism of Dapagliflozin can be decreased when combined with Terbinafine.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists