Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Vitamin K2 1% (MK-7) Ingredients & Drug Interactions

by BulkSupplements.com

Vitamin K2 1% (MK-7) label
See full label image
Powder Category: Vitamin
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Vitamin K2 1% (MK-7) against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Vitamin K2 1% (MK-7) is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for supporting normal blood clotting, bone health, heart and vascular health.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin K2. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Vitamin K2 1% (MK-7) by BulkSupplements.com

Ask about any prescription or over-the-counter medication and we check it for interactions with Vitamin K2 1% (MK-7) by BulkSupplements.com — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Vitamin K2 1% (MK-7) by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: vitamin K2 (in the form MK-7). The inactive ingredient is di-calcium phosphate, a common filler.

Vitamin K2 is a form of vitamin K, a fat-soluble nutrient that plays a role in blood clotting and bone health.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Vitamin K's overall clinical evidence instead.

Strong

Strong clinical evidence supports Vitamin K for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Hemorrhagic disease — rated "Effective" (Natural Medicines).
  • On file: Hypoprothrombinemia — rated "Effective" (Natural Medicines).
  • On file: Warfarin anticoagulation — rated "Effective" (Natural Medicines).
  • On file: Vitamin K-dependent clotting factors deficiency (VKCFD) — rated "Effective" (Natural Medicines).
  • On file: Osteoporosis — rated "Possibly Effective" (Natural Medicines).

The evidence supports vitamin K2 for treating vitamin K deficiency conditions — including low levels of vitamin K-dependent clotting factors and hemorrhagic disease (a bleeding disorder). It's also considered effective for correcting problems with warfarin anticoagulation in medical settings.

For osteoporosis, the evidence is less settled: vitamin K2 is rated possibly effective, meaning the data suggests a potential benefit but isn't conclusive enough yet.

The evidence, ingredient by ingredient Vitamin K

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

When taken by mouth, vitamin K is generally well tolerated by healthy people in typical supplement doses. The most common side effects are mild gastrointestinal upset — nausea, diarrhea, abdominal pain, and stomach discomfort — and these occur in only a small number of people.

The safety notes advise checking with your doctor before taking supplements, even though dietary amounts are considered fine. Vitamin K is rated likely safe in pregnancy and lactation.

Side effects, ingredient by ingredient Vitamin K

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin K.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

The main medication to double-check is warfarin (Coumadin) and other blood thinners — vitamin K can reduce their effect and that's a Major interaction. Before you start this product, run your exact medications through the interaction checker on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.

Vitamin K2 is useful if you have a documented deficiency or are managing certain clotting disorders under medical supervision. If you take warfarin or any blood thinner, talk to your pharmacist or doctor before starting this supplement — the interaction is serious and your medication's dose may need adjustment.

Pregnant or breastfeeding? The evidence supports it as likely safe, but run it by your provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vitamin K2 1% (MK-7), straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X002IKWQ35
Net contents 50 Gram(s); 1.76 Oz(s)
Market status On market
Date entered into DSLD Oct 22, 2021
DSLD ID 254713
Product type Vitamin
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vitamin K2 1% (MK-7) by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
9 mg
Maximum serving Sizes:
9 mg
Servings per container
5556
UPC/BARCODE
X002IKWQ35
IngredientAmount% DV
Vitamin K290 mcg75%

Other ingredients: Di-Calcium Phosphate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Clean & pure bulk supplements

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Formulation

Free Of: Soy, dairy, yeast, gluten, added sugars

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 9 mg once daily with food, or as directed by a physician. Use an accurate milligram scale to measure.

Storage

Store in a dry, cool, dark place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Vitamin K2 1% (MK-7) by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Vitamin K2 1% (MK-7) label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Vitamin K2 1% (MK-7) by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size9 mg Dosage formPowder Servings per container5556 Amounts shown are per serving.

Vitamin K2

Interacts with
2 drugs
90 mcg per serving Form: Menaquinone-7

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but suppl...

Vitamin K2 monograph & interactions

Other (inactive) ingredients: Di-Calcium Phosphate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vitamin K2 1% (MK-7) by BulkSupplements.com Drug Interactions

Want to check YOUR meds against Vitamin K2 1% (MK-7)?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2Drugs
2 Major

Ingredients driving the most interactions

Vitamin K2 2

Individual Drug Interactions

The ingredients in Vitamin K2 1% (MK-7) interact with 2 drugs. Click any drug to see the details.

1 of the 1 ingredient in Vitamin K2 1% (MK-7) interact with drugs. Each result below shows which ingredient is responsible. Vitamin K2

Each ingredient & the kinds of drugs it affects

For each ingredient in Vitamin K2 1% (MK-7) with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin K21 drug type · 2 drugs

Warfarin (Coumadin)

Vitamin K can antagonize and reverse the therapeutic effects of warfarin.
Vitamin K antagonizes the effects of warfarin. Excessive vitamin K intake, either from supplements or from changes in the diet, can reduce the anticoagulant effect of warfarin.

Likelihood Likely Evidence C
Vitamin K2 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Vitamin K2 1% (MK-7), from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
bulksupplements.com
Pharmacist Counseling Corner

Vitamin K2 1% (MK-7) by BulkSupplements.com: Common Questions

Does Vitamin K2 1% (MK-7) by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, Vitamin K2 1% (MK-7) has a known interaction with 2 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vitamin K2 1% (MK-7) contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will vitamin K2 work if I take warfarin?
No — this is actually the problem. Vitamin K blocks warfarin's blood-thinning effect, so the two work against each other. If you take warfarin, you need your doctor's okay before adding vitamin K2, and your dose may need to be adjusted.
What side effects might I notice?
Most people tolerate vitamin K well by mouth. If you do get side effects, they're usually mild — nausea, diarrhea, stomach upset, or abdominal pain. These are not common, and serious adverse effects are very rare.
Is this safe to take while pregnant or breastfeeding?
The data rates vitamin K2 as likely safe in pregnancy and lactation, which is reassuring. That said, any supplement during pregnancy or breastfeeding is worth checking with your doctor or midwife first for your specific situation.
What does vitamin K2 actually do?
Vitamin K2 plays a role in blood clotting and bone health. It's effective for treating vitamin K deficiency and related bleeding problems, and there's some evidence it may help with osteoporosis, though that's less certain.
Does this powder contain any fillers?
Yes — di-calcium phosphate is included as an inactive ingredient. It's a common filler used in supplements.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vitamin K2 1% (MK-7) is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vitamin K2 1% (MK-7) label
Go deeper

The Full Monographs Behind Vitamin K2 1% (MK-7)’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin K

Interacts with 2 drugs

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but supplements are sometimes used for deficiency...

Read the full Vitamin K monograph →
Sources

Sources & How We Checked

Vitamin K2 1% (MK-7)'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin K 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Crowther MA, Ageno W, Garcia D, et al. Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial. Ann Intern Med. 2009;150(5):293-300. PubMed
  4. Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation? Nutr Rev. 2010;68(3):178-81. PubMed
  5. Kim JS, Nafziger AN, Gaedigk A, et al. Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe. J Clin Pharmacol. 2001 Jul;41(7):715-22. PubMed
  6. Riegert-Johnson, D. L. and Volcheck, G. W. The incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective review. Ann.Allergy Asthma Immunol. 2002;89(4):400-406. PubMed
  7. Dezee, K. J., Shimeall, W. T., Douglas, K. M., Shumway, N. M., and O'malley, P. G. Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis. Arch.Intern.Med. 2-27-2006;166(4):391-397. DOI
  8. Dentali, F., Ageno, W., and Crowther, M. Treatment of coumarin-associated coagulopathy: a systematic review and proposed treatment algorithms. J.Thromb.Haemost. 2006;4(9):1853-1863. PubMed
  9. Caluwé R, Vandecasteele S, Van Vlem B, Vermeer C, De Vriese AS. Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study. Nephrol Dial Transplant. 2014;29(7):1385-90.
  10. Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Osteoporos Int. 2015;26(3):1175-86. PubMed
  11. Hunnali CR, Devi U, Kitchanan S, Sethuraman G. Three Different Regimens for Vitamin K Birth Prophylaxis in Infants Born Preterm: A Randomized Clinical Trial. J Pediatr 2023;255:98-104. PubMed

See these in context on the Vitamin K monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team