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Dietary supplement

Vitamin K2 50 mcg Ingredients & Drug Interactions

by Bronson

Softgel Capsule Category: Vitamin
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Vitamin K2 50 mcg is a dietary supplement by Bronson with 1 active ingredient. Its ingredients are commonly taken for supporting normal blood clotting, bone health, heart and vascular health.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin K2. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Vitamin K2 50 mcg by Bronson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: vitamin K2, a form of vitamin K at 50 mcg per softgel. Vitamin K plays a role in blood clotting and bone health.

The softgel itself is made from sunflower oil, gelatin, glycerin, medium chain triglyceride oil, caramel color, titanium dioxide, and purified water — all inactive ingredients that help deliver the vitamin.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Natural support for bone and cardiovascular health.
  • We looked for evidence on: Cardiovascular disease (CVD), Osteoporosis, Hemorrhagic disease, Hypoprothrombinemia, Vitamin K-dependent clotting factors deficiency (VKCFD), Warfarin anticoagulation — and 3 related terms.
  • The strongest evidence on file: Vitamin K is rated "Effective" for Hemorrhagic disease (Natural Medicines).
  • Also on file: Vitamin K is rated "Effective" for Hypoprothrombinemia, Warfarin anticoagulation, Vitamin K-dependent clotting factors deficiency (VKCFD).
  • Also on file: Vitamin K is rated "Possibly Effective" for Osteoporosis.

Vitamin K2 is effective for treating vitamin K deficiency conditions, including low clotting factors (hypoprothrombinemia and vitamin K-dependent clotting factors deficiency), hemorrhagic disease, and correcting warfarin anticoagulation when needed. For osteoporosis, the evidence is less clear — vitamin K2 is possibly effective, meaning there's some supporting research but it's not yet conclusive.

The evidence, ingredient by ingredient Vitamin K

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taken by mouth, vitamin K is generally well tolerated in amounts from food and most supplements. The most common side effects are mild and involve the stomach — nausea, diarrhea, and abdominal discomfort.

Serious side effects are rare. The safety data shows vitamin K2 is likely safe during pregnancy and lactation, so you don't need to avoid it in those periods.

That said, the safety notes remind us that while normal food amounts are fine, you should check with your doctor before taking supplements.

Side effects, ingredient by ingredient Vitamin K

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin K.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take warfarin (Coumadin) or any blood thinner in that class, double-check with your doctor or pharmacist before adding this supplement. Vitamin K can reduce the strength of blood thinners, which is a Major concern.

No other medication interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Vitamin K2 is a straightforward supplement for bone health and clotting support if you're not on a blood thinner. If you take warfarin or another blood thinner, do not start this without talking to your doctor first — it can interfere with how your medication works.

A few people may notice mild stomach upset, but most tolerate it well. Run your medications through the checker on this page, and confirm the okay with your own doctor or pharmacist before you begin.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 19, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vitamin K2 50 mcg, straight from the product label.

Brand Bronson
Barcode (UPC) 716563569020
Net contents 120 Softgel(s)
Market status On market
Date entered into DSLD Nov 19, 2021
DSLD ID 257986
Product type Vitamin
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vitamin K2 50 mcg by Bronson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
120
UPC/BARCODE
716563569020
IngredientAmount% DV
Vitamin K250 mcg42%

Other ingredients: Sunflower Oil, Gelatin, Glycerin, Medium Chain Triglyceride Oil, Caramel color, Titanium Dioxide, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Bronson Since 1960 Nutrition+

Formulation

Natural support for bone & cardiovascular health

FDA Statement of Identity

Dietary Supplement

Formula

120 count

Vitamin formulas

Suggested/Recommended/Usage/Directions

Once daily

Directions: As a dietary supplement for adults, take 1 softgel daily preferably with meals or as directed by a healthcare professional.

Precautions

Warning: Do not use if you are pregnant or nursing. If you are taking any medications consult your healthcare professional before use.

Do not use if seal under cap is broken or missing.

Keep out of reach of children.

Storage

Store at room temperature.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Discover the Bronson Difference To reorder: www.bronsonvitamins.com

See for yourself

Vitamin K2 50 mcg by Bronson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Vitamin K2 50 mcg by Bronson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container120 Amounts shown are per serving.

Vitamin K2

Interacts with
2 drugs
50 mcg per serving Form: Menaquinone-7

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but suppl...

Vitamin K2 monograph & interactions

Other (inactive) ingredients: Sunflower Oil, Gelatin, Glycerin, Medium Chain Triglyceride Oil, Caramel color, Titanium Dioxide, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vitamin K2 50 mcg by Bronson Drug Interactions

Want to check YOUR meds against Vitamin K2 50 mcg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2Drugs
2 Major

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Vitamin K2 50 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin K21 drug type · 2 drugs

Warfarin (Coumadin)

Vitamin K can antagonize and reverse the therapeutic effects of warfarin.
Vitamin K antagonizes the effects of warfarin. Excessive vitamin K intake, either from supplements or from changes in the diet, can reduce the anticoagulant effect of warfarin.

Likelihood Likely Evidence C
The maker

Brand information

Manufacturer and brand details for Vitamin K2 50 mcg, from the product label.

Bronson

Name
Bronson Laboratories
Street Address
350 South 400 West #102
City
Lindon
State
UT
ZipCode
84042
Phone Number
1-800-235-3200
Web Address
www.bronsonvitamins.com
Pharmacist Counseling Corner

Vitamin K2 50 mcg by Bronson: Common Questions

Does Vitamin K2 50 mcg by Bronson interact with any medications?
Yes. Based on its ingredients, Vitamin K2 50 mcg has a known interaction with 2 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vitamin K2 50 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does vitamin K2 actually work for bone health?
The evidence is mixed — it's rated possibly effective for osteoporosis, which means there's some research supporting it but we don't have enough data to call it a sure thing yet. Talk to your doctor about whether it makes sense for your situation.
Will this upset my stomach?
Most people tolerate it fine. Some do report mild nausea, diarrhea, or stomach discomfort when they take vitamin K by mouth, but serious side effects are rare.
Is it safe to take during pregnancy?
The safety data shows vitamin K2 is likely safe during pregnancy and while breastfeeding, so you don't need to skip it for those reasons. That said, always run any supplement decision by your own doctor during pregnancy or lactation.
Can I take this with my other medications?
Use the medication checker on this page to look up your exact drugs. The one major concern is warfarin and blood thinners — vitamin K can interfere with them, so check with your doctor first if you're on one.
What does the 50 mcg mean?
That's the dose — 50 micrograms of vitamin K2 per softgel. It's a moderate dose that most people can handle without issue.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vitamin K2 50 mcg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vitamin K2 50 mcg label
Go deeper

The Full Monographs Behind Vitamin K2 50 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Vitamin K2 50 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin K 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Crowther MA, Ageno W, Garcia D, et al. Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial. Ann Intern Med. 2009;150(5):293-300. PubMed
  4. Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation? Nutr Rev. 2010;68(3):178-81. PubMed
  5. Kim JS, Nafziger AN, Gaedigk A, et al. Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe. J Clin Pharmacol. 2001 Jul;41(7):715-22. PubMed
  6. Riegert-Johnson, D. L. and Volcheck, G. W. The incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective review. Ann.Allergy Asthma Immunol. 2002;89(4):400-406. PubMed
  7. Dezee, K. J., Shimeall, W. T., Douglas, K. M., Shumway, N. M., and O'malley, P. G. Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis. Arch.Intern.Med. 2-27-2006;166(4):391-397. DOI
  8. Dentali, F., Ageno, W., and Crowther, M. Treatment of coumarin-associated coagulopathy: a systematic review and proposed treatment algorithms. J.Thromb.Haemost. 2006;4(9):1853-1863. PubMed
  9. Caluwé R, Vandecasteele S, Van Vlem B, Vermeer C, De Vriese AS. Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study. Nephrol Dial Transplant. 2014;29(7):1385-90.
  10. Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Osteoporos Int. 2015;26(3):1175-86. PubMed
  11. Hunnali CR, Devi U, Kitchanan S, Sethuraman G. Three Different Regimens for Vitamin K Birth Prophylaxis in Infants Born Preterm: A Randomized Clinical Trial. J Pediatr 2023;255:98-104. PubMed

See these in context on the Vitamin K monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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