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Dietary supplement

Vitamin K2 as MK-7 100 mcg Ingredients & Drug Interactions

by Healthy Origins

Vitamin K2 as MK-7 100 mcg label
See full label image
Softgel Capsule Category: Vitamin
Most serious interaction: Major
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Vitamin K2 as MK-7 100 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Vitamin K2 as MK-7 100 mcg is a dietary supplement by Healthy Origins with 1 active ingredient. Its ingredients are commonly taken for supporting normal blood clotting, bone health, heart and vascular health.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin K2. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Vitamin K2 as MK-7 100 mcg by Healthy Origins

Ask about any prescription or over-the-counter medication and we check it for interactions with Vitamin K2 as MK-7 100 mcg by Healthy Origins — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Vitamin K2 as MK-7 100 mcg by Healthy Origins

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 24, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This supplement contains one active ingredient: vitamin K2 (as MK-7), at 100 micrograms per softgel. Vitamin K2 is a form of vitamin K that your body uses to regulate calcium in bone and soft tissue and to support blood clotting.

The softgel itself is made from vegetarian ingredients—a plant-based capsule, organic extra virgin olive oil, yellow beeswax, and sunflower lecithin—with no other active ingredients added.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: supports bone and cardiovascular health.
  • We looked for evidence on: Cardiovascular disease (CVD), Osteoporosis, Wound healing, bone density, vascular calcification, arterial stiffness.
  • The strongest evidence on file: Vitamin K is rated "Possibly Effective" for Osteoporosis (Natural Medicines).
  • Also on file: Vitamin K is rated "Insufficient Reliable Evidence To Rate" for Cardiovascular disease (CVD), Wound healing.

Vitamin K2 is established as effective for treating vitamin K deficiency conditions, including low clotting factors (VKCFD) and hemorrhagic disease, and for managing warfarin anticoagulation under medical supervision. The evidence for osteoporosis is less certain—the data shows vitamin K2 is possibly effective for bone density, meaning some studies suggest a benefit, but the case isn't proven yet.

The evidence, ingredient by ingredient Vitamin K

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, vitamin K is generally well tolerated in most people. The most common side effects are mild gastrointestinal upset—nausea, diarrhea, abdominal pain, and stomach upset—and a small number of people experience these.

Serious reactions are very rare when taken by mouth. Vitamin K2 is rated likely safe in pregnancy and lactation.

That said, because vitamin K interacts with warfarin, if you're pregnant or breastfeeding and take any blood-thinning medication, talk with your doctor or pharmacist before starting this supplement.

Side effects, ingredient by ingredient Vitamin K

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin K.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take warfarin (Coumadin) or any blood thinner, do not start this product without talking to your doctor first. Vitamin K can reduce how well your medication works, which could put you at risk for a blood clot.

Your doctor may want to adjust your dose or check your clotting levels more often.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This is a straightforward single-ingredient supplement useful if you have a vitamin K deficiency or want to explore the possibly-effective evidence for bone health. The main caution is warfarin and related blood thinners—if you take one, check with your doctor before adding this.

For anyone else, it's generally well tolerated with only mild digestive side effects in some people.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 19, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vitamin K2 as MK-7 100 mcg, straight from the product label.

Brand Healthy Origins
Barcode (UPC) 603573274429
Net contents 60 Veggie Softgel(s)
Market status On market
Date entered into DSLD May 19, 2022
DSLD ID 268974
Product type Vitamin
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vitamin K2 as MK-7 100 mcg by Healthy Origins, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
60
UPC/BARCODE
603573274429
IngredientAmount% DV
Vitamin K2100 mcg--

Other ingredients: Vegetarian Softgel, organic extra virgin Olive Oil, yellow Beeswax, Sunflower Lecithin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement for adults, take one (1) veggie softgel daily, or as recommended by a physician.

Formula

Healthy Origins Vitamin K2 (form Natto) provides vitamin K2 in its most biologically active form called Menaquinone-7 or MK-7 for short. Vitamin K2 as MK-7 has superior absorption and retention in the body when compared to vitamin K1--the typical supplemental form. Natural Vitamin K2 may help to support bone health, cardiovascular health, calcium metabolism and arterial health.

Storage

Store in a cool, dry place.

Precautions

Keep out of reach of children

Caution: Consult a physician before use if you are pregnant, nursing, taking medication or have a medical condition.

FDA Statement of Identity

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Dietary Supplement

Brand IP Statement(s)

Healthy Origins Since 1996

General Statements

New look

Formulation

Natural Supports bone & cardiovascular health

Suitable for vegetarians

Non GMO Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, peanut, or tree nut derived ingredients.

Manufactured in a cGMP facility.

Seals/Symbols

3rd party tested

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Vitamin K2 as MK-7 100 mcg by Healthy Origins label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Vitamin K2 as MK-7 100 mcg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Vitamin K2 as MK-7 100 mcg by Healthy Origins

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

Vitamin K2

Interacts with
2 drugs
100 mcg per serving Form: Menaquinone-7

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but suppl...

Vitamin K2 monograph & interactions

Other (inactive) ingredients: Vegetarian Softgel, Organic extra virgin Olive Oil, Yellow Beeswax, Sunflower Lecithin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vitamin K2 as MK-7 100 mcg by Healthy Origins Drug Interactions

Want to check YOUR meds against Vitamin K2 as MK-7 100 mcg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2Drugs
2 Major

Ingredients driving the most interactions

Vitamin K2 2

Individual Drug Interactions

The ingredients in Vitamin K2 as MK-7 100 mcg interact with 2 drugs. Click any drug to see the details.

1 of the 1 ingredient in Vitamin K2 as MK-7 100 mcg interact with drugs. Each result below shows which ingredient is responsible. Vitamin K2

Each ingredient & the kinds of drugs it affects

For each ingredient in Vitamin K2 as MK-7 100 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin K21 drug type · 2 drugs

Warfarin (Coumadin)

Vitamin K can antagonize and reverse the therapeutic effects of warfarin.
Vitamin K antagonizes the effects of warfarin. Excessive vitamin K intake, either from supplements or from changes in the diet, can reduce the anticoagulant effect of warfarin.

Likelihood Likely Evidence C
Vitamin K2 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Vitamin K2 as MK-7 100 mcg, from the product label.

Healthy Origins

See all Healthy Origins products
Name
Healthy Origins
City
Pittsburgh
State
PA
ZipCode
15241
Phone Number
1-888-228-6650
Pharmacist Counseling Corner

Vitamin K2 as MK-7 100 mcg by Healthy Origins: Common Questions

Does Vitamin K2 as MK-7 100 mcg by Healthy Origins interact with any medications?
Yes. Based on its ingredients, Vitamin K2 as MK-7 100 mcg has a known interaction with 2 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vitamin K2 as MK-7 100 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Vitamin K2 is rated likely safe during pregnancy and lactation. However, if you're on a blood thinner like warfarin, talk with your doctor or pharmacist before starting, because the interaction matters more in those situations.
What are the most common side effects?
Taken by mouth, vitamin K usually causes only mild stomach upset in some people—nausea, diarrhea, abdominal pain, or general stomach discomfort. Serious reactions are very rare.
Does this work for osteoporosis?
The evidence suggests vitamin K2 may help with bone density, but it's not proven yet. It's rated possibly effective, meaning some studies show promise but we need more research to be confident.
What is MK-7?
MK-7 (menaquinone-7) is a form of vitamin K2 that your body can use to activate proteins involved in bone and blood clotting. It's different from the K1 form found in leafy greens.
Is this vegetarian?
Yes—the softgel capsule is plant-based, and the oil fill is organic extra virgin olive oil. There's no gelatin or animal-derived ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vitamin K2 as MK-7 100 mcg label
Go deeper

The Full Monographs Behind Vitamin K2 as MK-7 100 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin K

Interacts with 2 drugs

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but supplements are sometimes used for deficiency...

Read the full Vitamin K monograph →
Sources

Sources & How We Checked

Vitamin K2 as MK-7 100 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin K 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Crowther MA, Ageno W, Garcia D, et al. Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial. Ann Intern Med. 2009;150(5):293-300. PubMed
  4. Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation? Nutr Rev. 2010;68(3):178-81. PubMed
  5. Kim JS, Nafziger AN, Gaedigk A, et al. Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe. J Clin Pharmacol. 2001 Jul;41(7):715-22. PubMed
  6. Riegert-Johnson, D. L. and Volcheck, G. W. The incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective review. Ann.Allergy Asthma Immunol. 2002;89(4):400-406. PubMed
  7. Dezee, K. J., Shimeall, W. T., Douglas, K. M., Shumway, N. M., and O'malley, P. G. Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis. Arch.Intern.Med. 2-27-2006;166(4):391-397. DOI
  8. Dentali, F., Ageno, W., and Crowther, M. Treatment of coumarin-associated coagulopathy: a systematic review and proposed treatment algorithms. J.Thromb.Haemost. 2006;4(9):1853-1863. PubMed
  9. Stevenson, M., Lloyd-Jones, M., and Papaioannou, D. Vitamin K to prevent fractures in older women: systematic review and economic evaluation. Health Technol.Assess. 2009;13(45):iii-134. PubMed
  10. Caluwé R, Vandecasteele S, Van Vlem B, Vermeer C, De Vriese AS. Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study. Nephrol Dial Transplant. 2014;29(7):1385-90.
  11. Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Osteoporos Int. 2015;26(3):1175-86. PubMed
  12. Hunnali CR, Devi U, Kitchanan S, Sethuraman G. Three Different Regimens for Vitamin K Birth Prophylaxis in Infants Born Preterm: A Randomized Clinical Trial. J Pediatr 2023;255:98-104. PubMed

See these in context on the Vitamin K monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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