Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Vitamin K2 Menaquinone-7 100 mcg Ingredients & Drug Interactions

by Basic Vitamins

Softgel Capsule Category: Vitamin
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Vitamin K2 Menaquinone-7 100 mcg is a dietary supplement by Basic Vitamins with 1 active ingredient. Its ingredients are commonly taken for supporting normal blood clotting, bone health, heart and vascular health.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin K2. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Vitamin K2 Menaquinone-7 100 mcg by Basic Vitamins

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Vitamin K2 (as menaquinone-7), at 100 mcg per softgel capsule. Vitamin K2 is a form of vitamin K that your body uses to help with blood clotting and may support bone health.

The inactive ingredients are sunflower seed oil, gelatin, vegetable glycerin, yellow beeswax, purified water, sunflower lecithin, carob, caramel, and calcium phosphate — these are fillers, binders, and capsule components that help deliver the active ingredient.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: vitamin K for bone and cardiovascular health.
  • We looked for evidence on: Cardiovascular disease (CVD), Hemorrhagic disease, Hypoprothrombinemia, Osteoporosis, Vitamin K-dependent clotting factors deficiency (VKCFD), Warfarin anticoagulation — and 3 related terms.
  • The strongest evidence on file: Vitamin K is rated "Effective" for Hemorrhagic disease (Natural Medicines).
  • Also on file: Vitamin K is rated "Effective" for Hypoprothrombinemia, Warfarin anticoagulation, Vitamin K-dependent clotting factors deficiency (VKCFD).
  • Also on file: Vitamin K is rated "Possibly Effective" for Osteoporosis.

Vitamin K2 is effective for correcting low blood levels of vitamin K (hypoprothrombinemia), treating vitamin K-dependent clotting factors deficiency, managing warfarin anticoagulation in clinical settings, and treating hemorrhagic disease. The evidence also suggests it may be helpful for osteoporosis, though that benefit is classified as possibly effective and not yet fully established.

The evidence, ingredient by ingredient Vitamin K

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taken by mouth, vitamin K is generally well tolerated for healthy people in food and supplement amounts. The most common side effects — mild gastrointestinal effects like nausea, diarrhea, stomach upset, and abdominal pain — occur in some users but are usually mild to moderate.

Serious side effects from oral vitamin K are very rare. Pregnancy and lactation: Vitamin K2 is rated likely safe during pregnancy and breastfeeding, but it's still wise to check with your doctor before starting any supplement during these times.

Side effects, ingredient by ingredient Vitamin K

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin K.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your pharmacist if you take warfarin (Coumadin) or any other blood thinner. Vitamin K can reduce their effectiveness, which is a Major concern.

We have not found documented interactions with other medications in our data, but that's not a guarantee — use the search tool on this page to verify your exact drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Vitamin K2 is a straightforward supplement for those who want to support their body's clotting ability or bone health. If you take warfarin or any other blood thinner, you must talk with your pharmacist or doctor first — vitamin K can interfere with how these drugs work.

Everyone else should run their medications through the checker below before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vitamin K2 Menaquinone-7 100 mcg, straight from the product label.

Brand Basic Vitamins
Barcode (UPC) 307610114104
Net contents 48 Softgel(s)
Market status On market
Date entered into DSLD Jun 23, 2021
DSLD ID 250024
Product type Vitamin
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vitamin K2 Menaquinone-7 100 mcg by Basic Vitamins, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
48
UPC/BARCODE
307610114104
IngredientAmount% DV
Vitamin K2100 mcg83%

Other ingredients: Sunflower seed Oil, Gelatin, Vegetable Glycerin, yellow Beeswax, purified Water, Sunflower Lecithin, Carob, Caramel, Calcium Phosphate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Keep out of the reach of children.

Do not use if inner seal is missing or broken.

Warning: If you are pregnant, nursing, taking any medications (especially anticoagulants [e.g. warfarin/coumadin]), consult your doctor before use.

If any adverse reactions occur, consult your healthcare practitioner.

Storage

Store in a dry place at room temperature.

General Statements

Basic's

Formulation

Gluten free

High quality basics

No artificial flavor or sweetener, no preservatives, no sugar, no starch, no milk, no lactose, no gluten, no wheat, no yeast, no fish.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: For adults, take one (1) softgel daily, preferably with a meal.

See for yourself

Vitamin K2 Menaquinone-7 100 mcg by Basic Vitamins label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Vitamin K2 Menaquinone-7 100 mcg by Basic Vitamins

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container48 Amounts shown are per serving.

Vitamin K2

Interacts with
2 drugs
100 mcg per serving Form: Menaquinone-7

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but suppl...

Vitamin K2 monograph & interactions

Other (inactive) ingredients: Sunflower seed Oil, Gelatin, Vegetable Glycerin, Yellow Beeswax, Purified Water, Sunflower Lecithin, Carob, Caramel, Calcium Phosphate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vitamin K2 Menaquinone-7 100 mcg by Basic Vitamins Drug Interactions

Want to check YOUR meds against Vitamin K2 Menaquinone-7 100 mcg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2Drugs
2 Major

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Vitamin K2 Menaquinone-7 100 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin K21 drug type · 2 drugs

Warfarin (Coumadin)

Vitamin K can antagonize and reverse the therapeutic effects of warfarin.
Vitamin K antagonizes the effects of warfarin. Excessive vitamin K intake, either from supplements or from changes in the diet, can reduce the anticoagulant effect of warfarin.

Likelihood Likely Evidence C
The maker

Brand information

Manufacturer and brand details for Vitamin K2 Menaquinone-7 100 mcg, from the product label.

Basic Vitamins

See all Basic Vitamins products
Name
Basic Drugs, Inc.
City
Vandalia
State
OH
ZipCode
45377
Phone Number
937-898-4010
Web Address
www.basicvitamins.com
Pharmacist Counseling Corner

Vitamin K2 Menaquinone-7 100 mcg by Basic Vitamins: Common Questions

Does Vitamin K2 Menaquinone-7 100 mcg by Basic Vitamins interact with any medications?
Yes. Based on its ingredients, Vitamin K2 Menaquinone-7 100 mcg has a known interaction with 2 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vitamin K2 Menaquinone-7 100 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does vitamin K2 actually work for bone health?
The evidence suggests it may help with osteoporosis, but that benefit is still considered possibly effective — not yet fully proven. It is effective for treating blood-clotting disorders and correcting low vitamin K levels.
Will this give me an upset stomach?
Vitamin K taken by mouth is generally well tolerated. Some people do experience mild nausea, diarrhea, or stomach upset, but these are not serious and aren't common. Most people take it without problems.
Can I take this if I'm pregnant or breastfeeding?
Vitamin K2 is rated likely safe during pregnancy and lactation. That said, it's always smart to talk with your doctor before adding any supplement when you're pregnant or nursing, just to make sure it fits your personal situation.
What is menaquinone-7, and why is it in this product?
Menaquinone-7 is simply another name for vitamin K2 — it's the specific form of vitamin K used here. Your body uses it for blood clotting and bone support.
Is this product safe for everyday use?
Yes, vitamin K is safe for regular use in supplement amounts for healthy people. Just remember to check with your doctor first if you take any blood thinners, and let your pharmacist know before you start it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vitamin K2 Menaquinone-7 100 mcg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vitamin K2 Menaquinone-7 100 mcg label
Go deeper

The Full Monographs Behind Vitamin K2 Menaquinone-7 100 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Vitamin K2 Menaquinone-7 100 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin K 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Crowther MA, Ageno W, Garcia D, et al. Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial. Ann Intern Med. 2009;150(5):293-300. PubMed
  4. Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation? Nutr Rev. 2010;68(3):178-81. PubMed
  5. Kim JS, Nafziger AN, Gaedigk A, et al. Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe. J Clin Pharmacol. 2001 Jul;41(7):715-22. PubMed
  6. Riegert-Johnson, D. L. and Volcheck, G. W. The incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective review. Ann.Allergy Asthma Immunol. 2002;89(4):400-406. PubMed
  7. Dezee, K. J., Shimeall, W. T., Douglas, K. M., Shumway, N. M., and O'malley, P. G. Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis. Arch.Intern.Med. 2-27-2006;166(4):391-397. DOI
  8. Dentali, F., Ageno, W., and Crowther, M. Treatment of coumarin-associated coagulopathy: a systematic review and proposed treatment algorithms. J.Thromb.Haemost. 2006;4(9):1853-1863. PubMed
  9. Caluwé R, Vandecasteele S, Van Vlem B, Vermeer C, De Vriese AS. Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study. Nephrol Dial Transplant. 2014;29(7):1385-90.
  10. Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Osteoporos Int. 2015;26(3):1175-86. PubMed
  11. Hunnali CR, Devi U, Kitchanan S, Sethuraman G. Three Different Regimens for Vitamin K Birth Prophylaxis in Infants Born Preterm: A Randomized Clinical Trial. J Pediatr 2023;255:98-104. PubMed

See these in context on the Vitamin K monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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