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Dietary supplement

Vitamin K2 MK-7 (Menaquinone-7) 45 mcg Ingredients & Drug Interactions

by Carlson

Vitamin K2 MK-7 (Menaquinone-7) 45 mcg label
See full label image
Softgel Capsule Category: Vitamin
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Vitamin K2 MK-7 (Menaquinone-7) 45 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Vitamin K2 MK-7 (Menaquinone-7) 45 mcg is a dietary supplement by Carlson with 1 active ingredient. Its ingredients are commonly taken for supporting normal blood clotting, bone health, heart and vascular health.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin K2. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Vitamin K2 MK-7 (Menaquinone-7) 45 mcg by Carlson

Ask about any prescription or over-the-counter medication and we check it for interactions with Vitamin K2 MK-7 (Menaquinone-7) 45 mcg by Carlson — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Vitamin K2 MK-7 (Menaquinone-7) 45 mcg by Carlson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: vitamin K2 (also called menaquinone-7), at 45 micrograms per softgel. Vitamin K2 is a form of vitamin K your body uses to support bone health and normal blood clotting.

The softgel capsule itself is made from safflower and sunflower oils with an antioxidant blend to preserve freshness.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Bone support and cardiovascular function.
  • We looked for evidence on: Cardiovascular disease (CVD), Osteoporosis, Hemorrhagic disease, Hypoprothrombinemia, Vitamin K-dependent clotting factors deficiency (VKCFD), Warfarin anticoagulation — and 3 related terms.
  • The strongest evidence on file: Vitamin K is rated "Effective" for Hemorrhagic disease (Natural Medicines).
  • Also on file: Vitamin K is rated "Effective" for Hypoprothrombinemia, Warfarin anticoagulation, Vitamin K-dependent clotting factors deficiency (VKCFD).
  • Also on file: Vitamin K is rated "Possibly Effective" for Osteoporosis.

Vitamin K2 is effective for treating vitamin K deficiency conditions — low clotting factors (hypoprothrombinemia and vitamin K-dependent clotting factor deficiency) and hemorrhagic disease — and it's effective for managing warfarin anticoagulation when used under medical supervision. For bone health and osteoporosis, the evidence is still developing; the data shows possibly effective, meaning there's some promise but we don't yet have strong proof.

The evidence, ingredient by ingredient Vitamin K

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taken by mouth, vitamin K is generally well tolerated by healthy people in normal dietary and supplement amounts. The most common side effects are mild: nausea, diarrhea, stomach upset, and abdominal pain — these are not serious and happen in a small number of users.

The safety notes advise checking with your doctor before taking supplements, especially if you have any health conditions or take medications.

Side effects, ingredient by ingredient Vitamin K

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin K.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take warfarin (Coumadin) or any blood thinner (anticoagulant), check with your pharmacist before starting this product. Vitamin K can reduce how well these drugs work and raise your clot risk.

No other interactions are documented in our data for this ingredient.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This supplement is for people interested in bone health or those correcting a vitamin K deficiency — but if you're on warfarin or any blood thinner, you must talk to your pharmacist or doctor first. Even people not on medications should mention this supplement to their provider before starting, since dietary vitamin K intake matters for how your body handles certain drugs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 26, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vitamin K2 MK-7 (Menaquinone-7) 45 mcg, straight from the product label.

Brand Carlson
Barcode (UPC) 088395101106
Net contents 90 Softgel(s)
Market status On market
Date entered into DSLD Dec 26, 2020
DSLD ID 241630
Product type Vitamin
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vitamin K2 MK-7 (Menaquinone-7) 45 mcg by Carlson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
90
UPC/BARCODE
088395101106
IngredientAmount% DV
Vitamin K245 mcg--

Other ingredients: Safflower Oil, Soft Gel Shell, Sunflower Oil, Antioxidant Blend

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Formulation

Bone support Cardiovascular function Calcium bioavailability

Gluten-free No artificial preservatives

Potency & quality guaranteed

An FDA regulated facility

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Warning: Vitamin K can antagonize the effect of anticoagulants, including Warfarin. Do not take this product if you are taking Warfarin or are pregnant or breastfeeding without first consulting with your physician.

Formula

Vitamin K as MK-7, derived from chickpeas, is important for the formation of strong, healthy bones and promotes arterial health.

Suggested/Recommended/Usage/Directions

Directions: Adults: take one soft gel daily at mealtime.

Storage

Keep bottle tightly closed. Store away from heat and moisture.

Brand IP Statement(s)

MenaQ7 vitamin K2 as MK-7 is a registered trademark of NattoPharma, Norwary. Patents granted and pending.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Vitamin K2 MK-7 (Menaquinone-7) 45 mcg by Carlson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Vitamin K2 MK-7 (Menaquinone-7) 45 mcg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Vitamin K2 MK-7 (Menaquinone-7) 45 mcg by Carlson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container90 Amounts shown are per serving.

Vitamin K2

Interacts with
2 drugs
45 mcg per serving Form: Menaquinone-7

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but suppl...

Vitamin K2 monograph & interactions

Other (inactive) ingredients: Safflower Oil, Soft Gel Shell, Sunflower Oil, Antioxidant Blend. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vitamin K2 MK-7 (Menaquinone-7) 45 mcg by Carlson Drug Interactions

Want to check YOUR meds against Vitamin K2 MK-7 (Menaquinone-7) 45 mcg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2Drugs
2 Major

Ingredients driving the most interactions

Vitamin K2 2

Individual Drug Interactions

The ingredients in Vitamin K2 MK-7 (Menaquinone-7) 45 mcg interact with 2 drugs. Click any drug to see the details.

1 of the 1 ingredient in Vitamin K2 MK-7 (Menaquinone-7) 45 mcg interact with drugs. Each result below shows which ingredient is responsible. Vitamin K2

Each ingredient & the kinds of drugs it affects

For each ingredient in Vitamin K2 MK-7 (Menaquinone-7) 45 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin K21 drug type · 2 drugs

Warfarin (Coumadin)

Vitamin K can antagonize and reverse the therapeutic effects of warfarin.
Vitamin K antagonizes the effects of warfarin. Excessive vitamin K intake, either from supplements or from changes in the diet, can reduce the anticoagulant effect of warfarin.

Likelihood Likely Evidence C
Vitamin K2 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Vitamin K2 MK-7 (Menaquinone-7) 45 mcg, from the product label.

Carlson

See all Carlson products
Name
Carlson Division of J.R. Carlson Laboratories, Inc.
City
Arlington Heights
State
IL
ZipCode
60004
Phone Number
888-234-5656
Web Address
www.carlsonlabs.com
Pharmacist Counseling Corner

Vitamin K2 MK-7 (Menaquinone-7) 45 mcg by Carlson: Common Questions

Does Vitamin K2 MK-7 (Menaquinone-7) 45 mcg by Carlson interact with any medications?
Yes. Based on its ingredients, Vitamin K2 MK-7 (Menaquinone-7) 45 mcg has a known interaction with 2 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vitamin K2 MK-7 (Menaquinone-7) 45 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on warfarin?
No — not without talking to your doctor or pharmacist first. Vitamin K reduces warfarin's effect and could lower your protection against clots. Your provider may need to adjust your warfarin dose or monitor you more closely if you do take a vitamin K supplement.
What side effects might I notice?
Most people have no side effects at all. If you do, they're usually mild and digestive: nausea, diarrhea, stomach upset, or abdominal pain. These are not serious, but if they don't settle in a day or two, let your pharmacist know.
Is it safe to take while pregnant or breastfeeding?
The data shows vitamin K2 is likely safe in pregnancy and lactation. That said, any supplement decision during pregnancy or while nursing should be discussed with your obstetrician or midwife for personalized guidance.
Does this supplement actually help with bone health?
There's some promise — the evidence is possibly effective — but we don't have strong proof yet. If bone health is your main goal, talk to your doctor about whether this fits into your overall plan.
What does vitamin K2 actually do in my body?
Vitamin K2 helps your body make proteins that are needed for normal blood clotting and bone health. You get some from food, but this supplement gives you an extra dose in a concentrated form.
Are there any fillers or additives I should know about?
The softgel contains safflower oil, sunflower oil, and an antioxidant blend in addition to the vitamin K2. There are no artificial colors, flavors, or major fillers — just the active ingredient and the capsule components.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vitamin K2 MK-7 (Menaquinone-7) 45 mcg label
Go deeper

The Full Monographs Behind Vitamin K2 MK-7 (Menaquinone-7) 45 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin K

Interacts with 2 drugs

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but supplements are sometimes used for deficiency...

Read the full Vitamin K monograph →
Sources

Sources & How We Checked

Vitamin K2 MK-7 (Menaquinone-7) 45 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin K 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Crowther MA, Ageno W, Garcia D, et al. Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial. Ann Intern Med. 2009;150(5):293-300. PubMed
  4. Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation? Nutr Rev. 2010;68(3):178-81. PubMed
  5. Kim JS, Nafziger AN, Gaedigk A, et al. Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe. J Clin Pharmacol. 2001 Jul;41(7):715-22. PubMed
  6. Riegert-Johnson, D. L. and Volcheck, G. W. The incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective review. Ann.Allergy Asthma Immunol. 2002;89(4):400-406. PubMed
  7. Dezee, K. J., Shimeall, W. T., Douglas, K. M., Shumway, N. M., and O'malley, P. G. Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis. Arch.Intern.Med. 2-27-2006;166(4):391-397. DOI
  8. Dentali, F., Ageno, W., and Crowther, M. Treatment of coumarin-associated coagulopathy: a systematic review and proposed treatment algorithms. J.Thromb.Haemost. 2006;4(9):1853-1863. PubMed
  9. Caluwé R, Vandecasteele S, Van Vlem B, Vermeer C, De Vriese AS. Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study. Nephrol Dial Transplant. 2014;29(7):1385-90.
  10. Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Osteoporos Int. 2015;26(3):1175-86. PubMed
  11. Hunnali CR, Devi U, Kitchanan S, Sethuraman G. Three Different Regimens for Vitamin K Birth Prophylaxis in Infants Born Preterm: A Randomized Clinical Trial. J Pediatr 2023;255:98-104. PubMed

See these in context on the Vitamin K monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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