No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Witch Hazel Ingredients & Drug Interactions

by TerraVita

Witch Hazel label
See full label image
Liquid Category: Botanical
No known interaction
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Witch Hazel against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Witch Hazel is a dietary supplement by TerraVita with 1 active ingredient. Its ingredients are commonly taken for skin irritation and inflammation, hemorrhoids, minor cuts and bruises.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

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HelloPharmacist Scorecard of Witch Hazel by TerraVita

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: witch hazel glycerite liquid extract, a plant-based preparation made from the witch hazel plant. The liquid is formulated with glycerin as an inactive ingredient (a humectant that helps preserve the preparation).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: skin health and minor wound care.
  • We looked for evidence on: Acne, Atopic dermatitis (eczema), Bruises, Burns, Hemorrhoids, Insect bite — and 4 related terms.
  • The strongest evidence on file: Witch Hazel is rated "Possibly Effective" for Hemorrhoids (Natural Medicines).
  • Also on file: Witch Hazel is rated "Possibly Ineffective" for Atopic dermatitis (eczema).
  • Also on file: Witch Hazel is rated "Insufficient Reliable Evidence To Rate" for Acne, Burns, Skin irritation, Sunburn, and more.

Witch hazel is possibly effective for hemorrhoids — the data supports its use for this purpose. For varicose veins and postmenopausal conditions, the evidence is too limited to rate either way.

For eczema (atopic dermatitis), it appears to be possibly ineffective, so it's not a strong choice if that's your main reason for using it.

The evidence, ingredient by ingredient Witch Hazel

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Witch hazel is generally well tolerated when applied to the skin short-term, though a small number of people develop contact dermatitis — redness or a burning sensation. Topical use carries low risk with limited safety data overall, but this product is not meant to be swallowed.

If you do take it by mouth, stick to appropriate doses; high oral doses are linked to kidney and liver damage because of the tannin content. The leaf contains 8% to 10% tannins and the bark up to 12%.

Pregnancy and lactation safety data aren't on file; talk with your doctor or pharmacist before using it during either.

Side effects, ingredient by ingredient Witch Hazel

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for the ingredients we could check. Still, run your medications through the tool on this page to be sure, or ask your pharmacist.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

TerraVita Witch Hazel is a single-ingredient topical product, best used for hemorrhoids. It's generally safe on the skin in the short term, though contact dermatitis can happen.

Avoid swallowing it, and if you're pregnant, breastfeeding, or have concerns about your skin condition, check with your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Witch Hazel, straight from the product label.

Brand TerraVita
Barcode (UPC) 064434284955
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Dec 13, 2022
DSLD ID 279451
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Witch Hazel by TerraVita, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
25 Drop(s)
Maximum serving Sizes:
40 Drop(s)
Servings per container
227
UPC/BARCODE
064434284955
IngredientAmount% DV
Witch Hazel Glycerite Liquid Extract0.13 mL--

Other ingredients: Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Copyright 2005 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Formula

Glycerite liquid extract (1:5)

Formulation

Alcohol free No flavor

Suggested/Recommended/Usage/Directions

Suggested Use: Take 25-40 drops of extract in a small amount of warm water 3-4 times daily. Shake well before using.

Precautions

Keep away from children.

Do not use if safety seal around cap is broken or missing.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Witch Hazel by TerraVita label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Witch Hazel label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Witch Hazel by TerraVita

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size25 Drop(s) Dosage formLiquid Servings per container227 Amounts shown are per serving.

Witch Hazel Glycerite Liquid Extract

No known
interactions
0.13 mL per serving

Witch hazel is a plant-based astringent used mostly on the skin for minor irritation, hemorrhoids, and oily skin. It is generally well tolerated as a...

Witch Hazel Glycerite Liquid Extract monograph & interactions

Other (inactive) ingredients: Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Witch Hazel by TerraVita Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Witch Hazel. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Witch Hazel, from the product label.

TerraVita

See all TerraVita products
Name
ZooScape LLC
Phone Number
844-449-0444
Web Address
www.ZooScape.com
Pharmacist Counseling Corner

Witch Hazel by TerraVita: Common Questions

Does Witch Hazel by TerraVita interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Witch Hazel. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Witch Hazel contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use TerraVita Witch Hazel if I'm pregnant or breastfeeding?
Safety data for pregnancy and lactation aren't on file for witch hazel. Talk with your doctor or pharmacist before using it during either — they can give you personalized advice based on your situation.
Is it safe to swallow this product?
No, this product is not meant to be taken by mouth. It's formulated for topical use only. High oral doses of witch hazel can cause kidney and liver damage due to its tannin content.
Will witch hazel help my eczema?
The data shows witch hazel is possibly ineffective for eczema, so it's not a strong choice for that condition. Your doctor or pharmacist can suggest alternatives that may work better.
What are the most common side effects when I apply it to my skin?
Contact dermatitis — redness or a burning sensation — is the most common side effect when applied topically. It happens in a small number of people. If it occurs, stop use and rinse the area.
Does this product have fillers or other inactive ingredients?
Yes, glycerin is included as an inactive ingredient to help preserve the preparation. It's the only inactive ingredient in this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Witch Hazel is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Witch Hazel label
Go deeper

The Full Monographs Behind Witch Hazel’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Witch Hazel

Witch hazel is a plant-based astringent used mostly on the skin for minor irritation, hemorrhoids, and oily skin. It is generally well tolerated as a topical product for short-term use, but...

Read the full Witch Hazel monograph →
Sources

Sources & How We Checked

Witch Hazel's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Witch Hazel 7 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
  4. Hormann HP, Korting HC. Evidence for the efficacy and safety of topical herbal drugs in dermatology: part I: anti-inflammatory agents. Phytomedicine 1994;1:161-71. PubMed
  5. Wolff, H. H. and Kieser, M. Hamamelis in children with skin disorders and skin injuries: results of an observational study. Eur.J.Pediatr. 2007;166(9):943-948. PubMed
  6. Khanna, N. and Datta, Gupta S. Rejuvenating facial massage--a bane or boon? Int J Dermatol. 2002;41(7):407-410. PubMed
  7. Theisen LL, Erdelmeier CA, Spoden GA, Boukhallouk F, Sausy A, Florin L, Muller CP. Tannins from Hamamelis virginiana bark extract: characterization and improvement of the antiviral efficacy against influenza A virus and human papillomavirus. PLoS One. 201 PubMed

See these in context on the Witch Hazel monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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