No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Yucca Ingredients & Drug Interactions

by Nature's Sunshine

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Yucca is a dietary supplement by Nature's Sunshine with 1 active ingredient. Its ingredients are commonly taken for joint pain and arthritis, digestive health, high cholesterol.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Yucca by Nature's Sunshine

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: yucca. It comes in a capsule form with a capsule shell as the inactive ingredient.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Yucca's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Structural system support.
  • We looked for evidence on: Joint pain, Hypercholesterolemia, Hypertension, Arthritis, Inflammation.
  • The closest evidence on file: Yucca is rated "Insufficient Reliable Evidence To Rate" for Hypercholesterolemia (Natural Medicines).
  • Also on file: Yucca is rated "Insufficient Reliable Evidence To Rate" for Hypertension, Joint pain.

The evidence for yucca isn't established in the data we hold. The monograph shows insufficient reliable evidence to rate it for bleeding, joint pain, or dandruff — the main uses people reach for it.

That doesn't mean it doesn't work; it means the studies aren't there yet to back up those claims.

The evidence, ingredient by ingredient Yucca

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Yucca is generally considered low-risk in food amounts, but supplement safety isn't well studied. The data notes there isn't enough safety information available, so caution is warranted.

If you've had allergic reactions to plants — especially contact allergies or reactions to weeping fig or spathe flower — yucca may trigger a similar response. Environmental exposure has been linked to allergic rhinitis in people sensitized to yucca, and topical contact can cause skin reactions including contact urticaria (hives) and phytodermatitis (plant-caused skin inflammation).

Side effects, ingredient by ingredient Yucca

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Still, if you take any prescription medications, run them through the checker on this page or ask your pharmacist before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Yucca has no documented drug interactions, but the evidence for whether it actually works for joint pain, bleeding, or dandruff isn't established. If you have plant allergies or atopic skin, be cautious.

Talk to your pharmacist before starting, especially if you're pregnant, breastfeeding, or taking any medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Yucca, straight from the product label.

Brand Nature's Sunshine
Barcode (UPC) 099904007703
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2019
DSLD ID 205793
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Yucca by Nature's Sunshine, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
099904007703
IngredientAmount% DV
Yucca450 mg--

Other ingredients: Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

10007701118 Guaranteed pure Traditionally used for structural system support

Nature's Sunshine uses natural source materials that are subject to color variation. Product of U.S.A. Herb specialists since 1972 Quality, service, integrity

Suggested/Recommended/Usage/Directions

Recommendation Take one capsule with a meal twice daily.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

This bottle was sealed for your protection. Do not use if inner seal is missing or damaged.

FDA Statement of Identity

Dietary Supplement

See for yourself

Yucca by Nature's Sunshine label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Yucca by Nature's Sunshine

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Yucca

No known
interactions
450 mg per serving

Yucca is a desert plant traditionally used for joint pain, arthritis, and digestion, and it contains compounds called saponins thought to have anti-in...

Yucca monograph & interactions

Other (inactive) ingredients: Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Yucca by Nature's Sunshine Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Yucca. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Yucca, from the product label.

Nature's Sunshine

See all Nature's Sunshine products
Name
Nature's Sunshine Products, Inc
City
Spanish Fork
State
Utah
ZipCode
84660
Phone Number
1-800-223-8225
Web Address
www.naturessunshine.com
Pharmacist Counseling Corner

Yucca by Nature's Sunshine: Common Questions

Does Yucca by Nature's Sunshine interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Yucca. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Yucca contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is yucca safe to take while pregnant or breastfeeding?
There isn't enough safety information to know either way. Pregnancy safety data is not on file, and breastfeeding safety is unknown — the data advises against use while breastfeeding. Talk with your doctor or pharmacist for personalized advice based on your situation.
Does yucca actually work for joint pain or arthritis?
The evidence isn't established. The data shows insufficient reliable evidence to rate yucca for joint pain. That means we don't have solid studies backing that claim yet, so we can't say whether it works.
Can yucca cause allergic reactions?
Yes. People sensitized to yucca can develop allergic rhinitis from environmental exposure, and direct contact can cause contact hives or plant-caused skin inflammation. If you've reacted to similar plants like weeping fig, be extra careful.
How safe is yucca as a supplement?
It's generally considered low-risk in food amounts, but supplement safety isn't well studied. The data notes there isn't enough information available, so caution is warranted — especially if you have allergies or sensitive skin.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Yucca is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Yucca label
Go deeper

The Full Monographs Behind Yucca’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Yucca's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Yucca 3 references
  1. <p><span>Kanerva, L., Estlander, T., Petman, L., Makinen-Kiljunen, S. Occupational allergic contact urticaria to yucca (Yucca aloifolia), weeping fig (Ficus benjamina), and spathe flower (Spathiphyllum wallisii). Allergy. 2001;56(10): 1008-11.</span></p>
  2. Poljacki, M., Paravina, M., Jovanovic, M., Subotic, M., and Duran, V. [Contact allergic dermatitis caused by plants]. Med Pregl. 1993;46(9-10):371-375.
  3. Mahillon, V., Saussez, S., and Michel, O. High incidence of sensitization to ornamental plants in allergic rhinitis. Allergy 2006;61(9):1138-1140. PubMed

See these in context on the Yucca monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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