No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Yucca Ingredients & Drug Interactions

by Nature's Sunshine

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Yucca is a dietary supplement by Nature's Sunshine with 1 active ingredient. Its ingredients are commonly taken for joint pain and arthritis, digestive health, high cholesterol.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Yucca by Nature's Sunshine

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: yucca. Yucca is a plant-based ingredient historically used in traditional medicine, though its modern clinical use and effectiveness remain unclear.

The capsule itself is an inactive ingredient — just a delivery shell.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Yucca's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: traditionally used for structural system support.
  • We looked for evidence on: Joint pain, arthritis, musculoskeletal health, connective tissue.
  • The closest evidence on file: Yucca is rated "Insufficient Reliable Evidence To Rate" for Joint pain (Natural Medicines).

The evidence on yucca is sparse. The data we hold rates its effectiveness for bleeding, joint pain, and dandruff as insufficient — meaning there isn't enough reliable evidence yet to say whether it works for these purposes.

If you're considering it for one of these reasons, you'd be relying on traditional use rather than solid clinical proof.

The evidence, ingredient by ingredient Yucca

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Yucca is generally well tolerated in small food amounts, but supplement safety hasn't been well studied. The safety data we have raises caution: not enough information is available to say it's safe during pregnancy or while breastfeeding, so those are reasons to avoid it if you fall into either group.

Some people have reported allergic reactions — including allergic rhinitis (itchy, inflamed nasal passages) and contact urticaria (hives) — after occupational or skin exposure to yucca. If you have a known plant allergy or sensitive skin, mention this product to your doctor or pharmacist before starting.

Side effects, ingredient by ingredient Yucca

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the medications we could check. Run your exact medications through the interaction tool on this page to be certain.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Yucca may interest you if you're drawn to traditional plant remedies, but the clinical evidence for its effectiveness isn't established. If you're pregnant, breastfeeding, or have a history of plant allergies, talk with your doctor or pharmacist before trying it.

No medication interactions are documented, but that doesn't mean the product is thoroughly researched — bring it up with your healthcare provider if you're on any medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Yucca, straight from the product label.

Brand Nature's Sunshine
Barcode (UPC) 099904007703
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2019
DSLD ID 205793
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Yucca by Nature's Sunshine, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
099904007703
IngredientAmount% DV
Yucca450 mg--

Other ingredients: Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

10007701118 Guaranteed pure Traditionally used for structural system support

Nature's Sunshine uses natural source materials that are subject to color variation. Product of U.S.A. Herb specialists since 1972 Quality, service, integrity

Suggested/Recommended/Usage/Directions

Recommendation Take one capsule with a meal twice daily.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

This bottle was sealed for your protection. Do not use if inner seal is missing or damaged.

FDA Statement of Identity

Dietary Supplement

See for yourself

Yucca by Nature's Sunshine label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Yucca by Nature's Sunshine

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Yucca

No known
interactions
450 mg per serving

Yucca is a desert plant traditionally used for joint pain, arthritis, and digestion, and it contains compounds called saponins thought to have anti-in...

Yucca monograph & interactions

Other (inactive) ingredients: Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Yucca by Nature's Sunshine Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Yucca. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Yucca, from the product label.

Nature's Sunshine

See all Nature's Sunshine products
Name
Nature's Sunshine Products, Inc
City
Spanish Fork
State
Utah
ZipCode
84660
Phone Number
1-800-223-8225
Web Address
www.naturessunshine.com
Pharmacist Counseling Corner

Yucca by Nature's Sunshine: Common Questions

Does Yucca by Nature's Sunshine interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Yucca. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Yucca contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is yucca safe during pregnancy?
The safety data we have doesn't give us enough information to say either way. Because there's insufficient safety data, it's best to avoid yucca while pregnant. Talk with your doctor or pharmacist about whether it's right for you.
Is yucca safe while breastfeeding?
Safety while breastfeeding is unknown, so the data advises against use. If you're interested in taking it, check with your doctor or pharmacist for personalized guidance.
Can yucca help with joint pain?
The evidence we hold rates yucca's effectiveness for joint pain as insufficient — there just isn't enough reliable research to say whether it works. It's been used traditionally, but clinical proof is lacking.
Can yucca trigger allergies?
Yes. Environmental exposure to yucca has been linked to allergic rhinitis in some people, and skin contact has caused hives and contact dermatitis (skin irritation) in others. If you have a plant allergy or sensitive skin, mention this product to your doctor or pharmacist before starting.
Is this product just yucca, or does it have other active ingredients?
This is a single-ingredient product — just yucca in a capsule. The capsule itself is an inactive ingredient used to deliver the yucca.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Yucca is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Yucca label
Go deeper

The Full Monographs Behind Yucca’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Yucca's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Yucca 3 references
  1. <p><span>Kanerva, L., Estlander, T., Petman, L., Makinen-Kiljunen, S. Occupational allergic contact urticaria to yucca (Yucca aloifolia), weeping fig (Ficus benjamina), and spathe flower (Spathiphyllum wallisii). Allergy. 2001;56(10): 1008-11.</span></p>
  2. Poljacki, M., Paravina, M., Jovanovic, M., Subotic, M., and Duran, V. [Contact allergic dermatitis caused by plants]. Med Pregl. 1993;46(9-10):371-375.
  3. Mahillon, V., Saussez, S., and Michel, O. High incidence of sensitization to ornamental plants in allergic rhinitis. Allergy 2006;61(9):1138-1140. PubMed

See these in context on the Yucca monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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