No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Zi Su Ye Alcohol Free Ingredients & Drug Interactions

by Herbal Terra

Liquid Category: Botanical
No known interaction
The interaction bottom line No known interaction

Zi Su Ye Alcohol Free is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for seasonal and food allergies, asthma and airway inflammation, atopic dermatitis (eczema).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Zi Su Ye Alcohol Free by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product has one active ingredient: perilla leaf extract. Perilla is a plant used in traditional medicine and cooking, particularly in Asian cuisines.

The extract is delivered in a liquid base of glycerin and water, with no alcohol.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Perilla product and its label doesn't state a use — see Perilla's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for perilla leaf extract isn't established in the data we hold. The ingredient has been studied for age-related cognitive decline, hay fever, asthma, osteoporosis, cancer, and headache, but current research doesn't support a reliable rating for any of these uses.

If you're considering this for a specific health concern, talk with your pharmacist or doctor about whether the evidence supports it for your situation.

The evidence, ingredient by ingredient Perilla

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Perilla is generally well tolerated when used as a food, but supplement-strength products haven't been well studied, so caution is warranted. The main risk to know about is anaphylaxis — a severe allergic reaction — which has been reported in some people who consumed perilla seeds, particularly.

Topically applied perilla can cause dermatitis (skin irritation) in some cases. Occupational exposure to smoke from roasted perilla seeds has triggered asthma in workers.

During pregnancy and breastfeeding, there isn't enough safety data to support medicinal amounts of perilla, so the data advises against it. If you're pregnant or nursing and interested in this product, talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Perilla

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for the ingredients we could check in this product.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Perilla leaf extract has a long history in food and traditional use, but as a supplement it's not well studied and its effectiveness for the conditions it's been tested against isn't established. If you have a known allergy to perilla seeds or related plants, this isn't for you.

Otherwise, talk with your pharmacist if you're pregnant, nursing, or have questions about whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Zi Su Ye Alcohol Free, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 7238360830392
Net contents 2 Fluid Ounce(s); 60 mL
Market status On market
Date entered into DSLD Mar 25, 2025
DSLD ID 324721
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Zi Su Ye Alcohol Free by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
60
UPC/BARCODE
7238360830392
IngredientAmount% DV
Perilla frutescens Leaf Extract, Dry1156 mg--

Other ingredients: Glycerin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz. of juice or water up to 4 times a day.

Precautions

We recommend to seek expert medical advice before taking. May have contraindications and cause adverse reaction.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications. Keep out of the reach of children!

Do not use if you are allergic to any ingredients.

Storage

Store in a cool, dry, dark place.

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

Formulation

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

Sugar free

Expertly extracted 100% natural Premium product

No alcohol (ethyl), artificial ingredients, color additives, fillers or binders.

Natural Gluten free

Formula

Perilla frutescens

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA

General Statements

Organic Raw Material.

See for yourself

Zi Su Ye Alcohol Free by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Zi Su Ye Alcohol Free by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

1156 mg per serving

Perilla is an Asian mint-family plant used in cooking and traditional medicine, mainly for allergy, breathing, and digestive complaints. Most human ev...

Perilla frutescens Leaf Extract, Dry monograph & interactions

Other (inactive) ingredients: Glycerin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Zi Su Ye Alcohol Free by Herbal Terra Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Zi Su Ye Alcohol Free. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Zi Su Ye Alcohol Free, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra LLC
Phone Number
+18083857868
Web Address
herbalterra.com
Pharmacist Counseling Corner

Zi Su Ye Alcohol Free by Herbal Terra: Common Questions

Does Zi Su Ye Alcohol Free by Herbal Terra interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Zi Su Ye Alcohol Free. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Zi Su Ye Alcohol Free contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is perilla safe if I have a perilla seed allergy?
No — skip this product. Anaphylaxis (a severe allergic reaction) has been reported in people who consumed perilla seeds, and perilla leaf extract comes from the same plant. If you're allergic to perilla seeds or related plants, this isn't safe for you.
Can I use this while pregnant or breastfeeding?
The safety data advises against medicinal amounts of perilla during pregnancy and breastfeeding because there isn't enough information to know it's safe. If you're pregnant or nursing and want to use this product, talk with your doctor or pharmacist for advice tailored to your situation.
Does perilla leaf extract actually work for any of the conditions listed?
The evidence isn't established in the data we hold. Perilla has been studied for cognitive decline, hay fever, asthma, osteoporosis, cancer, and headache, but current research doesn't support a reliable rating for any of them.
What are the most common side effects?
Orally, perilla seems to be well tolerated in most people. The main serious risk is anaphylaxis — a rare but severe allergic reaction. If you apply it to your skin, dermatitis (skin irritation) can happen in some cases.
Is this product the same as using perilla as a food?
Not quite. Perilla as a food is generally well tolerated, but supplement-strength products like this one haven't been well studied, so caution is warranted. The dose and form matter.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Zi Su Ye Alcohol Free is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Zi Su Ye Alcohol Free label
Go deeper

The Full Monographs Behind Zi Su Ye Alcohol Free’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Zi Su Ye Alcohol Free's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Perilla 4 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Kanzaki, T. and Kimura, S. Occupational allergic contact dermatitis from Perilla frutescens (shiso). Contact Dermatitis 1992;26(1):55-56.
  3. Yu H, Qiu JF, Ma LJ, Hu YJ, Li P, Wan JB. Phytochemical and phytopharmacological review of Perilla frutescens L. (Labiatae), a traditional edible-medicinal herb in China. Food Chem Toxicol 2017;108(Pt B):375-91. PubMed
  4. Jeong K, Lee SY, Jeon SA, et al. Clinical and immunological characterization of perilla seed allergy in children. J Investig Allergol Clin Immunol 2021. PubMed

See these in context on the Perilla monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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