Zymegest Ingredients & Drug Interactions
by DC
What is this page for?
First and foremost: checking Zymegest against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Zymegest is a dietary supplement by DC with 5 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Zymegest by DC
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Zymegest contains 5 active ingredients, all digestive enzymes and bile support. Protease and lipase break down protein and fat in food to aid digestion.
Pancreatin is a blend of multiple digestive enzymes (amylase, protease, and lipase) that work together. Bile extract supports fat breakdown and absorption.
Amylase and cellulase round out the enzyme mix to help break down carbohydrates and plant fiber. The tablet also contains inactive ingredients — calcium phosphate, stearic acid, cellulose, silica, riboflavin, and vanillin — that serve as binders and fillers.
Does it work?
Not established
The evidence for these enzymes is limited. Lipase has been studied for inflammatory bowel disease, dyspepsia (indigestion), and prematurity, but the data we hold shows insufficient reliable evidence to rate it for any of these uses.
The same applies to the other enzymes in this product — we don't have established effectiveness ratings for them. If you're considering Zymegest for a specific digestive condition, talk with your pharmacist about what the research actually shows for your situation.
How safe is it?
Well-documented data
Protease and lipase are generally well tolerated in adults, though some people report digestive upset or allergic reactions — rarely, occupational exposure to protease has triggered allergic rhinitis or asthma. Neither enzyme is recommended during pregnancy without medical advice, and breastfeeding use should be discussed with your healthcare provider first due to limited safety data.
Lipase does carry a rare risk of serious gastrointestinal effects (including necrotizing enterocolitis) in premature infants when added to formula or breast milk, but this applies only to a specialized recombinant form, not typical supplements. People with serious digestive conditions should use lipase under medical guidance.
We have no safety data on file for amylase, cellulase, or bile extract.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. That said, we hold no interaction data for amylase, cellulase, or bile extract — not because they're safe, but because we haven't reviewed them.
Use the search tool on this page to look up your specific medications.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.
Zymegest may help with general digestive support if enzyme deficiency is your concern, but evidence for specific conditions is sparse. It's generally well tolerated by healthy adults.
Pregnant or breastfeeding people, those with serious digestive disorders, and anyone on regular medications should check with their pharmacist first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Zymegest, straight from the product label.
| Brand | DC |
|---|---|
| Barcode (UPC) | 052301298907 |
| Net contents | 90 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Feb 23, 2022 |
| DSLD ID | 266637 |
| Product type | Other Combinations |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Zymegest by DC, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 0 NP | -- |
| Protease | 0 NP | -- |
| Lipase | 0 NP | -- |
| Cellulase | 2 mg | -- |
| Pancreatin | 100 mg | -- |
| Bile extract | 50 mg | -- |
Other ingredients: Calcium Phosphate, Stearic Acid, Cellulose, Silica, Riboflavin, Vanillin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: As a food enzyme dietary supplement, take 1 tablet with each meal and if necessary at bedtime. Don't hesitate to use two servings (2 tablets) with each meal and at bedtime if needed.
Precautions
Tamper Evident: Do not use this product if imprinted foil seal under cap is broken or missing.
Keep out of reach of children.
Caution: If you are pregnant or nursing do not take this product.
Contains milk ingredients.
Formulation
Manufactured in our own state-of-the-art FDA Registered Facility (Registration #1023013) using Good Manufacturing Practices (GMPs) assuring correct potencies, freshness, quality and purity.
Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.
Made in USA
Gluten free
Nutritionally supports digestive health
Storage
Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
Quali Pure
Formula
Pancreatic enzyme concentrate containing amylase, protease and lipase with cellulase and bile extract
FDA Statement of Identity
Food Enzyme Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Zymegest by DC label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Zymegest by DC
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Other (inactive) ingredients: Calcium Phosphate, Stearic Acid, Cellulose, Silica, Riboflavin, Vanillin. These complete the product’s ingredient list but are not active constituents.
Zymegest by DC Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Zymegest. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Zymegest, from the product label.
DC
See all DC products- Name
- Dee Cee Laboratories, Inc.
- Street Address
- 304 Dee Cee Ct.
- City
- White House
- State
- TN
- ZipCode
- 37188
Zymegest by DC: Common Questions
Does Zymegest by DC interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What exactly are these enzymes and why are they in here?
Can I take Zymegest if I'm pregnant?
Is this safe while breastfeeding?
What are the side effects?
Does this actually work for indigestion or digestive problems?
Are there any fillers or other ingredients I should know about?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Zymegest is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Zymegest’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Proteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monographLipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph →Sources & How We Checked
Zymegest's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC