Idelalisib

Generic name: Pronounced as (eye del'' a lis' ib)
Brand names
  • Zydelig®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 04/15/2018

Idelalisib may cause serious or life threatening liver damage. Tell your doctor if you have or ever have had liver disease. The risk of liver damage may be increased in people taking other medications known to cause liver damage, and in people who already have liver disease. Tell your doctor and pharmacist about the medications you are taking so they can check whether any of your medications may increase the risk that you will develop liver damage during your treatment with idelalisib. If you experience any of the following symptoms, call your doctor immediately: extreme tiredness, loss of appetite, weight loss, nausea, vomiting, unusual bleeding or bruising, yellowing of the skin or eyes, dark yellow or brown-colored urine, pale stools, or pain in the upper right part of the stomach.

Idelalisib may cause diarrhea, colitis (swelling of the large intestine), or holes in the stomach or intestine. Tell your doctor if you have diarrhea or if you have ever had colitis or other conditions that affect your stomach or intestine. The risk of diarrhea may be increased in people taking other medications known to cause diarrhea. Tell your doctor and pharmacist about the medications you are taking so they can check whether any of your medications may increase the risk that you will develop diarrhea during your treatment with idelalisib.If you experience any of the following symptoms, call your doctor immediately: if your number of bowel movements in a day increases by 6 or more , stomach cramps or pain, chills, fever, nausea, or vomiting.

Idelalisib may cause serious or life threatening pneumonitis (swelling of the lungs). Tell your doctor if you have lung disease or breathing problems. If you experience any of the following symptoms, call your doctor immediately: new or worsening cough, difficulty breathing, wheezing, or shortness of breath.

Idelalisib may cause serious or life threatening infections. Tell your doctor if you have an infection, or if you have or have ever had cytomegalovirus (CMV; a viral infection that may cause symptoms in patients with weak immune systems). If you experience any of the following symptoms, call your doctor immediately: fever, sore throat, chills, painful, frequent, or difficult urination, or other signs of infection.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests to check your body's response to idelalisib.

Talk to your doctor about the risks of taking idelalisib.

Idelalisib is used along with another medication rituximab (Rituxan) to treat chronic lymphocytic leukemia (CLL; a type of cancer that begins in the white blood cells) in people whose cancer came back after receiving other cancer treatments. It is also used to treat certain types of follicular lymphoma (FL; a type of cancer that begins in the white blood cells) and small lymphocytic lymphoma (SLL:a type of cancer that begins in the white blood cells) in people whose cancer came back after being treated with at least 2 other cancer treatments. Idelalisib is in a class of medications called kinase inhibitors. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps stop the spread of cancer cells.

Idelalisib comes as a tablet to take by mouth. It is usually taken with or without food twice a day. Take idelalisib at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take idelalisib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the tablets whole; do not split, chew, or crush them.

Your doctor may decrease your dose of idelalisib or tell you to stop taking the medication for a time or permanently if you experience serious side effects during your treatment. This depends on how well the medication works for you and the side effects you experience. Talk to your doctor about how you are feeling during your treatment. Continue to take idelalisib even if you feel well. Do not stop taking idelalisib without talking to your doctor.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking idelalisib,

  • tell your doctor and pharmacist if you are allergic to idelalisib, any other medications, or any of the ingredients in idelalisib tablets. If you have ever had a severe allergic reaction in the past, such as swelling of your face, lips or throat; difficulty swallowing or breathing; or peeling, blistering skin, your doctor will probably tell you not to take idelalisib.Ask your pharmacist or check the Medication Guide for a list of the ingredients.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: carbamazepine (Carbatrol, Epitol, Equetro, others); clarithromycin (Biaxin, in PrevPac); itraconazole (Onmel, Sporanox); ketoconazole (Nizoral); medications used to treat human immunodeficiency virus (HIV) such as efavirenz (Sustiva, in Atripla), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, in Kaletra, in Technivie); midazolam; nefazodone; phenobarbital; phenytoin (Dilantin, Phenytek); pioglitazone (Actos, in Actoplus Met, in Duetact, in Oseni); rifabutin (Mycobutin); and rifampin (Rifadin, Rimactane, in Rifamate, in Rifater). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with idelalisib, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor and pharmacist what herbal products you are taking, especially St. John's wort. You should not take St. John's wort during your treatment with idelalisib.

  • tell your doctor if you are pregnant, plan to become pregnant, or plan to father a child. You should not become pregnant during your treatment with idelalisib. You should use birth control to prevent pregnancy during your treatment with idelalisib and at least 1 month after your final dose. If you are a male and your partner can become pregnant, you should use effective birth control during your treatment and for 3 months after your final dose. If you or your partner become pregnant while taking idelalisib, call your doctor immediately. Idelalisib may harm the fetus.

  • tell your doctor if you are breastfeeding. You should not breastfeed while you are taking idelalisib and for at least one month after your final dose.

Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medication.

If you miss a dose of idelalisib by less than 6 hours, take the missed dose as soon as you remember it and then take the next dose at the scheduled time. However, if you miss a dose by more than 6 hours, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Idelalisib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • headache

    • difficulty falling asleep or staying asleep

    • decreased appetite

    • increased thirst

    • heartburn

    • joint pain

    • night sweats

    • lack of energy

    • swelling of the hands, feet, ankles, or lower legs

  • Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately or get emergency medical treatment:

    • red, itching, peeling, or blistering skin

    • painful sores or ulcers on your skin, lips, or in your mouth

    • difficulty swallowing or breathing; swelling of the face, lips, or throat; hives; itching

  • Idelalisib may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light, excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Repaglinide Repaglinide The excretion of Repaglinide can be decreased when combined with Idelalisib.
Leflunomide Leflunomide The risk or severity of adverse effects can be increased when Idelalisib is combined with Leflunomide.
Delavirdine Delavirdine The metabolism of Idelalisib can be decreased when combined with Delavirdine.
Atorvastatin Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Idelalisib.
Aminophylline Aminophylline The metabolism of Aminophylline can be decreased when combined with Idelalisib.
Cilostazol Cilostazol The metabolism of Cilostazol can be decreased when combined with Idelalisib.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The metabolism of Idelalisib can be decreased when combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The excretion of Conjugated estrogens can be decreased when combined with Idelalisib.
Fenofibrate Fenofibrate The metabolism of Idelalisib can be decreased when combined with Fenofibrate.
Methylergonovine Methylergonovine The metabolism of Idelalisib can be decreased when combined with Methylergometrine.
Mycophenolate Mycophenolate The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with Idelalisib.
Paregoric Paregoric The serum concentration of Idelalisib can be increased when it is combined with Morphine.
Prednisone Prednisone The risk or severity of adverse effects can be increased when Prednisone is combined with Idelalisib.
Reserpine Reserpine The serum concentration of Idelalisib can be increased when it is combined with Reserpine.
Sumatriptan Sumatriptan The excretion of Sumatriptan can be decreased when combined with Idelalisib.
Tacrolimus Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Idelalisib.
Triamcinolone Triamcinolone The metabolism of Idelalisib can be increased when combined with Triamcinolone.
Doxycycline Injection Doxycycline Injection The metabolism of Idelalisib can be decreased when combined with Doxycycline.
Fluconazole Injection Fluconazole Injection The metabolism of Idelalisib can be decreased when combined with Fluconazole.
Interferon Beta-1b Injection Interferon Beta-1b Injection The risk or severity of adverse effects can be increased when Interferon beta-1b is combined with Idelalisib.
Interferon Gamma-1b Injection Interferon Gamma-1b Injection The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Idelalisib.
Meperidine Injection Meperidine Injection The metabolism of Idelalisib can be increased when combined with Meperidine.
Methylprednisolone Injection Methylprednisolone Injection The metabolism of Idelalisib can be increased when combined with Methylprednisolone.
Metronidazole Injection Metronidazole Injection The metabolism of Idelalisib can be decreased when combined with Metronidazole.
Morphine Injection Morphine Injection The serum concentration of Idelalisib can be increased when it is combined with Morphine.
Zidovudine Injection Zidovudine Injection The risk or severity of adverse effects can be increased when Zidovudine is combined with Idelalisib.
Cyclosporine Cyclosporine Idelalisib may increase the immunosuppressive activities of Cyclosporine.
Torsemide Torsemide The excretion of Torasemide can be decreased when combined with Idelalisib.
Olanzapine Olanzapine The metabolism of Olanzapine can be decreased when combined with Idelalisib.
Dofetilide Dofetilide The metabolism of Dofetilide can be decreased when combined with Idelalisib.
Hydroxychloroquine Hydroxychloroquine The risk or severity of adverse effects can be increased when Hydroxychloroquine is combined with Idelalisib.
Orlistat Orlistat The metabolism of Idelalisib can be increased when combined with Orlistat.
Oxcarbazepine Oxcarbazepine The metabolism of Idelalisib can be increased when combined with Oxcarbazepine.
Pantoprazole Pantoprazole Pantoprazole may decrease the excretion rate of Idelalisib which could result in a higher serum level.
Telmisartan Telmisartan Telmisartan may decrease the excretion rate of Idelalisib which could result in a higher serum level.
Temozolomide Temozolomide The risk or severity of adverse effects can be increased when Temozolomide is combined with Idelalisib.
Anakinra Anakinra The metabolism of Idelalisib can be increased when combined with Anakinra.
Linezolid Linezolid The risk or severity of adverse effects can be increased when Linezolid is combined with Idelalisib.
Trimipramine Trimipramine The serum concentration of Trimipramine can be increased when it is combined with Idelalisib.
Etanercept Injection Etanercept Injection The metabolism of Idelalisib can be increased when combined with Etanercept.
Modafinil Modafinil The metabolism of Idelalisib can be increased when combined with Modafinil.
Tenofovir Tenofovir The metabolism of Idelalisib can be decreased when combined with Tenofovir.
Sirolimus Sirolimus The risk or severity of adverse effects can be increased when Idelalisib is combined with Sirolimus.
Epinephrine Injection Epinephrine Injection The metabolism of Idelalisib can be decreased when combined with Epinephrine.
Epirubicin Epirubicin The risk or severity of adverse effects can be increased when Epirubicin is combined with Idelalisib.
Zonisamide Zonisamide The serum concentration of Idelalisib can be increased when it is combined with Zonisamide.
Adalimumab Injection Adalimumab Injection The metabolism of Idelalisib can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Idelalisib.
Ezetimibe Ezetimibe The excretion of Ezetimibe can be decreased when combined with Idelalisib.
Glatiramer Injection Glatiramer Injection The risk or severity of adverse effects can be increased when Glatiramer is combined with Idelalisib.
Atazanavir Atazanavir The metabolism of Idelalisib can be decreased when combined with Atazanavir.
Mefloquine Mefloquine The metabolism of Idelalisib can be decreased when combined with Mefloquine.
Rosuvastatin Rosuvastatin The metabolism of Idelalisib can be decreased when combined with Rosuvastatin.
Vardenafil Vardenafil The metabolism of Vardenafil can be decreased when combined with Idelalisib.
Alfuzosin Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Idelalisib.
Aprepitant Aprepitant The metabolism of Idelalisib can be decreased when combined with Aprepitant.
Tegaserod Tegaserod The serum concentration of Idelalisib can be increased when it is combined with Tegaserod.
Progesterone Progesterone The metabolism of Idelalisib can be increased when combined with Progesterone.
Darbepoetin Alfa Injection Darbepoetin Alfa Injection The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Idelalisib.
Infliximab Injection Infliximab Injection The metabolism of Idelalisib can be increased when combined with Infliximab.
Rifaximin Rifaximin The metabolism of Idelalisib can be increased when combined with Rifaximin.
Duloxetine Duloxetine The metabolism of Idelalisib can be decreased when combined with Duloxetine.
Norethindrone Norethindrone The metabolism of Idelalisib can be decreased when combined with Norethisterone.
Bosentan Bosentan The metabolism of Bosentan can be increased when combined with Idelalisib.
Natalizumab Injection Natalizumab Injection The risk or severity of adverse effects can be increased when Idelalisib is combined with Natalizumab.
Erlotinib Erlotinib The metabolism of Idelalisib can be decreased when combined with Erlotinib.
Eszopiclone Eszopiclone The metabolism of Eszopiclone can be decreased when combined with Idelalisib.
Voriconazole Voriconazole The metabolism of Idelalisib can be decreased when combined with Voriconazole.
Peginterferon Alfa-2a Injection Peginterferon Alfa-2a Injection The risk or severity of adverse effects can be increased when Peginterferon alfa-2a is combined with Idelalisib.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The risk or severity of adverse effects can be increased when Peginterferon alfa-2b is combined with Idelalisib.
Fentanyl Fentanyl The metabolism of Fentanyl can be decreased when combined with Idelalisib.
Deferasirox Deferasirox The metabolism of Idelalisib can be increased when combined with Deferasirox.
Tipranavir Tipranavir The metabolism of Idelalisib can be decreased when combined with Tipranavir.
Felbamate Felbamate The metabolism of Idelalisib can be increased when combined with Felbamate.
Ranolazine Ranolazine The serum concentration of Idelalisib can be increased when it is combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Idelalisib can be increased when combined with Abatacept.
Imatinib Imatinib The metabolism of Idelalisib can be decreased when combined with Imatinib.
Sitagliptin Sitagliptin The serum concentration of Idelalisib can be increased when it is combined with Sitagliptin.
Bevacizumab Injection Bevacizumab Injection The risk or severity of adverse effects can be increased when Bevacizumab is combined with Idelalisib.
Gefitinib Gefitinib The metabolism of Idelalisib can be decreased when combined with Gefitinib.
Paliperidone Paliperidone The serum concentration of Idelalisib can be increased when it is combined with Paliperidone.
Bortezomib Bortezomib The risk or severity of adverse effects can be increased when Bortezomib is combined with Idelalisib.
Clofarabine Injection Clofarabine Injection The risk or severity of adverse effects can be increased when Clofarabine is combined with Idelalisib.
Hepatitis B Vaccine Hepatitis B Vaccine The therapeutic efficacy of Hepatitis B Vaccine (Recombinant) can be decreased when used in combination with Idelalisib.
Influenza Vaccine, Inactivated or Recombinant Influenza Vaccine, Inactivated or Recombinant The therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Idelalisib.
Influenza Vaccine, Live Intranasal Influenza Vaccine, Live Intranasal The risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Idelalisib.
Live Shingles (Zoster) Vaccine (ZVL) Live Shingles (Zoster) Vaccine (ZVL) The risk or severity of infection can be increased when Varicella Zoster Vaccine (Live/attenuated) is combined with Idelalisib.
Oxaliplatin Injection Oxaliplatin Injection The risk or severity of adverse effects can be increased when Oxaliplatin is combined with Idelalisib.
Posaconazole Posaconazole The metabolism of Idelalisib can be decreased when combined with Posaconazole.
Primaquine Primaquine The metabolism of Idelalisib can be decreased when combined with Primaquine.
Rituximab Injection Rituximab Injection The risk or severity of adverse effects can be increased when Rituximab is combined with Idelalisib.
Darunavir Darunavir The serum concentration of Idelalisib can be increased when it is combined with Darunavir.
Pemetrexed Injection Pemetrexed Injection The risk or severity of adverse effects can be increased when Pemetrexed is combined with Idelalisib.
Retapamulin Retapamulin The metabolism of Retapamulin can be decreased when combined with Idelalisib.
Vorinostat Vorinostat The risk or severity of adverse effects can be increased when Vorinostat is combined with Idelalisib.
Sorafenib Sorafenib The metabolism of Idelalisib can be decreased when combined with Sorafenib.
Sunitinib Sunitinib The metabolism of Idelalisib can be decreased when combined with Sunitinib.
Dronabinol Dronabinol Dronabinol may decrease the excretion rate of Idelalisib which could result in a higher serum level.
Lapatinib Lapatinib The metabolism of Idelalisib can be decreased when combined with Lapatinib.
Dasatinib Dasatinib The metabolism of Idelalisib can be decreased when combined with Dasatinib.
Armodafinil Armodafinil The metabolism of Idelalisib can be increased when combined with Armodafinil.
Azacitidine Injection Azacitidine Injection The risk or severity of adverse effects can be increased when Azacitidine is combined with Idelalisib.
Ivermectin Ivermectin The metabolism of Idelalisib can be increased when combined with Ivermectin.
Temsirolimus Temsirolimus The risk or severity of adverse effects can be increased when Temsirolimus is combined with Idelalisib.
Nelarabine Injection Nelarabine Injection The risk or severity of adverse effects can be increased when Nelarabine is combined with Idelalisib.
Lenalidomide Lenalidomide The risk or severity of adverse effects can be increased when Lenalidomide is combined with Idelalisib.
Nilotinib Nilotinib The metabolism of Idelalisib can be decreased when combined with Nilotinib.
Toremifene Toremifene The serum concentration of Idelalisib can be increased when it is combined with Toremifene.
Bexarotene Bexarotene The metabolism of Idelalisib can be increased when combined with Bexarotene.
Budesonide Budesonide The metabolism of Idelalisib can be increased when combined with Budesonide.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Idelalisib can be decreased when combined with Chloramphenicol.
Decitabine Injection Decitabine Injection The risk or severity of adverse effects can be increased when Decitabine is combined with Idelalisib.
Etravirine Etravirine The metabolism of Idelalisib can be increased when combined with Etravirine.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of adverse effects can be increased when Arsenic trioxide is combined with Idelalisib.
Mitoxantrone Injection Mitoxantrone Injection The metabolism of Idelalisib can be decreased when combined with Mitoxantrone.
Desvenlafaxine Desvenlafaxine The metabolism of Desvenlafaxine can be decreased when combined with Idelalisib.
Tretinoin Tretinoin The risk or severity of adverse effects can be increased when Tretinoin is combined with Idelalisib.
Bendamustine Injection Bendamustine Injection The risk or severity of adverse effects can be increased when Bendamustine is combined with Idelalisib.
Pilocarpine Pilocarpine The metabolism of Idelalisib can be decreased when combined with Pilocarpine.
Certolizumab Injection Certolizumab Injection The metabolism of Idelalisib can be increased when combined with Certolizumab pegol.
Ixabepilone Injection Ixabepilone Injection The risk or severity of adverse effects can be increased when Ixabepilone is combined with Idelalisib.
Irinotecan Injection Irinotecan Injection The risk or severity of adverse effects can be increased when Irinotecan is combined with Idelalisib.
Estramustine Estramustine The risk or severity of adverse effects can be increased when Estramustine is combined with Idelalisib.
Mitotane Mitotane The metabolism of Idelalisib can be increased when combined with Mitotane.
Alemtuzumab Injection (Chronic Lymphocytic Leukemia) Alemtuzumab Injection (Chronic Lymphocytic Leukemia) The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Idelalisib.
Rufinamide Rufinamide The metabolism of Idelalisib can be increased when combined with Rufinamide.
Silodosin Silodosin The serum concentration of Idelalisib can be increased when it is combined with Silodosin.
Midazolam Midazolam The serum concentration of Midazolam can be increased when it is combined with Idelalisib.
Dexrazoxane Injection Dexrazoxane Injection The risk or severity of adverse effects can be increased when Dexrazoxane is combined with Idelalisib.
Eltrombopag Eltrombopag Eltrombopag may decrease the excretion rate of Idelalisib which could result in a higher serum level.
Ibritumomab Injection Ibritumomab Injection The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Idelalisib.
Milnacipran Milnacipran The metabolism of Idelalisib can be decreased when combined with Milnacipran.
Iloperidone Iloperidone The metabolism of Iloperidone can be decreased when combined with Idelalisib.
Lacosamide Lacosamide The metabolism of Idelalisib can be decreased when combined with Lacosamide.
Everolimus Everolimus The risk or severity of adverse effects can be increased when Idelalisib is combined with Everolimus.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The metabolism of Idelalisib can be decreased when combined with Tolvaptan.
Dronedarone Dronedarone The serum concentration of Idelalisib can be increased when it is combined with Dronedarone.
Pralatrexate Injection Pralatrexate Injection The risk or severity of adverse effects can be increased when Pralatrexate is combined with Idelalisib.
Romidepsin Injection Romidepsin Injection The metabolism of Romidepsin can be decreased when combined with Idelalisib.
Topotecan Topotecan The metabolism of Idelalisib can be increased when combined with Topotecan.
Golimumab Injection Golimumab Injection The metabolism of Idelalisib can be increased when combined with Golimumab.
Pazopanib Pazopanib The metabolism of Idelalisib can be decreased when combined with Pazopanib.
Asenapine Asenapine The metabolism of Asenapine can be decreased when combined with Idelalisib.
Pitavastatin Pitavastatin The excretion of Pitavastatin can be decreased when combined with Idelalisib.
Albendazole Albendazole The metabolism of Idelalisib can be decreased when combined with Albendazole.
Denosumab Injection Denosumab Injection The risk or severity of adverse effects can be increased when Denosumab is combined with Idelalisib.
Tocilizumab Injection Tocilizumab Injection The metabolism of Idelalisib can be increased when combined with Tocilizumab.
Fingolimod Fingolimod Idelalisib may increase the immunosuppressive activities of Fingolimod.
Eribulin Injection Eribulin Injection The risk or severity of adverse effects can be increased when Eribulin is combined with Idelalisib.
Cabazitaxel Injection Cabazitaxel Injection The risk or severity of adverse effects can be increased when Cabazitaxel is combined with Idelalisib.
Acetaminophen Injection Acetaminophen Injection The metabolism of Idelalisib can be increased when combined with Acetaminophen.
Denileukin Diftitox Injection Denileukin Diftitox Injection The metabolism of Idelalisib can be decreased when combined with Aldesleukin.
Sipuleucel-T Injection Sipuleucel-T Injection The therapeutic efficacy of Sipuleucel-T can be decreased when used in combination with Idelalisib.
Belimumab Injection Belimumab Injection The risk or severity of adverse effects can be increased when Belimumab is combined with Idelalisib.
Busulfan Injection Busulfan Injection The risk or severity of adverse effects can be increased when Idelalisib is combined with Busulfan.
Roflumilast Roflumilast Roflumilast may increase the immunosuppressive activities of Idelalisib.
Linagliptin Linagliptin The metabolism of Idelalisib can be decreased when combined with Linagliptin.
Rilpivirine Rilpivirine The metabolism of Idelalisib can be decreased when combined with Rilpivirine.
Telaprevir Telaprevir The metabolism of Glecaprevir can be decreased when combined with Idelalisib.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Idelalisib can be increased when combined with Cyclophosphamide.
Rivaroxaban Rivaroxaban The serum concentration of Idelalisib can be increased when it is combined with Rivaroxaban.
Ticagrelor Ticagrelor The metabolism of Idelalisib can be decreased when combined with Ticagrelor.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The metabolism of Idelalisib can be decreased when combined with Brentuximab vedotin.
Ruxolitinib Ruxolitinib The risk or severity of adverse effects can be increased when Idelalisib is combined with Ruxolitinib.
Vandetanib Vandetanib The metabolism of Idelalisib can be decreased when combined with Vandetanib.
Clobazam Clobazam The metabolism of Idelalisib can be increased when combined with Clobazam.
Vemurafenib Vemurafenib The serum concentration of Idelalisib can be increased when it is combined with Vemurafenib.
Vismodegib Vismodegib Vismodegib may decrease the excretion rate of Idelalisib which could result in a higher serum level.
Belatacept Injection Belatacept Injection The risk or severity of adverse effects can be increased when Belatacept is combined with Idelalisib.
Ivacaftor Ivacaftor The metabolism of Idelalisib can be decreased when combined with Ivacaftor.
Basiliximab Injection Basiliximab Injection The risk or severity of adverse effects can be increased when Basiliximab is combined with Idelalisib.
Axitinib Axitinib The metabolism of Axitinib can be decreased when combined with Idelalisib.
Crizotinib Crizotinib The metabolism of Crizotinib can be decreased when combined with Idelalisib.
Melphalan Injection Melphalan Injection The risk or severity of adverse effects can be increased when Melphalan is combined with Idelalisib.
Cabergoline Cabergoline The metabolism of Idelalisib can be decreased when combined with Cabergoline.
Naloxone Injection Naloxone Injection The metabolism of Idelalisib can be decreased when combined with Naloxone.
Ambrisentan Ambrisentan The serum concentration of Ambrisentan can be increased when it is combined with Idelalisib.
Eculizumab Injection Eculizumab Injection The risk or severity of adverse effects can be increased when Eculizumab is combined with Idelalisib.
Carfilzomib Injection Carfilzomib Injection The risk or severity of adverse effects can be increased when Carfilzomib is combined with Idelalisib.
Enzalutamide Enzalutamide The metabolism of Idelalisib can be increased when combined with Enzalutamide.
Mirabegron Mirabegron The serum concentration of Idelalisib can be increased when it is combined with Mirabegron.
Regorafenib Regorafenib The metabolism of Idelalisib can be decreased when combined with Regorafenib.
Bosutinib Bosutinib The metabolism of Idelalisib can be decreased when combined with Bosutinib.
Corticotropin, Repository Injection Corticotropin, Repository Injection The metabolism of Idelalisib can be increased when combined with Corticotropin.
Teriflunomide Teriflunomide The risk or severity of adverse effects can be increased when Teriflunomide is combined with Idelalisib.
Tofacitinib Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Idelalisib.
Dimethyl Fumarate Dimethyl Fumarate The risk or severity of adverse effects can be increased when Dimethyl fumarate is combined with Idelalisib.
Ponatinib Ponatinib The risk or severity of adverse effects can be increased when Ponatinib is combined with Idelalisib.
Pomalidomide Pomalidomide The risk or severity of adverse effects can be increased when Pomalidomide is combined with Idelalisib.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Idelalisib can be decreased when combined with Trastuzumab emtansine.
Apixaban Apixaban The serum concentration of Idelalisib can be increased when it is combined with Apixaban.
Canagliflozin Canagliflozin The serum concentration of Idelalisib can be increased when it is combined with Canagliflozin.
Dabrafenib Dabrafenib The metabolism of Dabrafenib can be increased when combined with Idelalisib.
Trametinib Trametinib The metabolism of Idelalisib can be increased when combined with Trametinib.
Dolutegravir Dolutegravir The serum concentration of Idelalisib can be increased when it is combined with Dolutegravir.
Afatinib Afatinib Afatinib may decrease the excretion rate of Idelalisib which could result in a higher serum level.
Perampanel Perampanel The metabolism of Idelalisib can be increased when combined with Perampanel.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Idelalisib.
Lomitapide Lomitapide The metabolism of Idelalisib can be decreased when combined with Lomitapide.
Obinutuzumab Injection Obinutuzumab Injection The risk or severity of adverse effects can be increased when Obinutuzumab is combined with Idelalisib.
Simeprevir Simeprevir The metabolism of Simeprevir can be decreased when combined with Idelalisib.
Sofosbuvir Sofosbuvir The serum concentration of Idelalisib can be increased when it is combined with Sofosbuvir.
Apremilast Apremilast The metabolism of Idelalisib can be increased when combined with Apremilast.
Ceritinib Ceritinib The metabolism of Idelalisib can be decreased when combined with Ceritinib.
Siltuximab Injection Siltuximab Injection The metabolism of Idelalisib can be increased when combined with Siltuximab.
Eslicarbazepine Eslicarbazepine The metabolism of Idelalisib can be increased when combined with Eslicarbazepine.
Vedolizumab Injection Vedolizumab Injection The risk or severity of adverse effects can be increased when Vedolizumab is combined with Idelalisib.
Belinostat Injection Belinostat Injection The risk or severity of adverse effects can be increased when Belinostat is combined with Idelalisib.
Testosterone Injection Testosterone Injection The metabolism of Idelalisib can be increased when combined with Testosterone.
Oritavancin Injection Oritavancin Injection The metabolism of Idelalisib can be increased when combined with Oritavancin.
Vorapaxar Vorapaxar The metabolism of Idelalisib can be decreased when combined with Vorapaxar.
Suvorexant Suvorexant The metabolism of Idelalisib can be decreased when combined with Suvorexant.
Edoxaban Edoxaban The serum concentration of Edoxaban can be increased when it is combined with Idelalisib.
Peginterferon Beta-1a Injection Peginterferon Beta-1a Injection The risk or severity of adverse effects can be increased when Idelalisib is combined with Peginterferon beta-1a.
Olaparib Olaparib The metabolism of Idelalisib can be decreased when combined with Olaparib.
Blinatumomab Injection Blinatumomab Injection The risk or severity of adverse effects can be increased when Blinatumomab is combined with Idelalisib.
Caspofungin Injection Caspofungin Injection The excretion of Caspofungin can be decreased when combined with Idelalisib.
Tasimelteon Tasimelteon The metabolism of Idelalisib can be decreased when combined with Tasimelteon.
Lanreotide Injection Lanreotide Injection The metabolism of Idelalisib can be decreased when combined with Lanreotide.
Pirfenidone Pirfenidone The risk or severity of adverse effects can be increased when Pirfenidone is combined with Idelalisib.
Nintedanib Nintedanib The metabolism of Idelalisib can be decreased when combined with Nintedanib.
Secukinumab Injection Secukinumab Injection The metabolism of Idelalisib can be increased when combined with Secukinumab.
Palbociclib Palbociclib The metabolism of Idelalisib can be decreased when combined with Palbociclib.
Lenvatinib Lenvatinib The metabolism of Idelalisib can be increased when combined with Lenvatinib.
Panobinostat Panobinostat The risk or severity of adverse effects can be increased when Idelalisib is combined with Panobinostat.
Dinutuximab Injection Dinutuximab Injection The risk or severity of adverse effects can be increased when Idelalisib is combined with Dinutuximab.
Haloperidol Injection Haloperidol Injection The serum concentration of Haloperidol can be increased when it is combined with Idelalisib.
Isavuconazonium Injection Isavuconazonium Injection The serum concentration of Isavuconazonium can be increased when it is combined with Idelalisib.
Sonidegib Sonidegib The metabolism of Sonidegib can be decreased when combined with Idelalisib.
Flibanserin Flibanserin The serum concentration of Idelalisib can be increased when it is combined with Flibanserin.
Rolapitant Rolapitant The serum concentration of Idelalisib can be increased when it is combined with Rolapitant.
Prednisolone Prednisolone The metabolism of Idelalisib can be increased when combined with Prednisolone.
Daclatasvir Daclatasvir Daclatasvir may decrease the excretion rate of Idelalisib which could result in a higher serum level.
Ziprasidone Injection Ziprasidone Injection The metabolism of Idelalisib can be decreased when combined with Ziprasidone.
Eluxadoline Eluxadoline The serum concentration of Eluxadoline can be increased when it is combined with Idelalisib.
Cobimetinib Cobimetinib The metabolism of Idelalisib can be decreased when combined with Cobimetinib.
Mepolizumab Injection Mepolizumab Injection The risk or severity of adverse effects can be increased when Mepolizumab is combined with Idelalisib.
Trabectedin Injection Trabectedin Injection The risk or severity of adverse effects can be increased when Idelalisib is combined with Trabectedin.
Osimertinib Osimertinib The metabolism of Idelalisib can be increased when combined with Osimertinib.
Alectinib Alectinib The metabolism of Idelalisib can be decreased when combined with Alectinib.
Ixazomib Ixazomib The metabolism of Ixazomib can be decreased when combined with Idelalisib.
Rifapentine Rifapentine The metabolism of Idelalisib can be increased when combined with Rifapentine.
Lesinurad Lesinurad The metabolism of Idelalisib can be increased when combined with Lesinurad.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection The metabolism of Idelalisib can be decreased when combined with Amphotericin B.
Dexamethasone Injection Dexamethasone Injection The metabolism of Idelalisib can be increased when combined with Dexamethasone.
Ixekizumab Injection Ixekizumab Injection The risk or severity of adverse effects can be increased when Idelalisib is combined with Ixekizumab.
Venetoclax Venetoclax The metabolism of Idelalisib can be decreased when combined with Venetoclax.
Cobicistat Cobicistat The metabolism of Idelalisib can be decreased when combined with Cobicistat.
Selexipag Selexipag The serum concentration of Selexipag can be increased when it is combined with Idelalisib.
Rucaparib Rucaparib The metabolism of Rucaparib can be decreased when combined with Idelalisib.
Ribociclib Ribociclib The metabolism of Idelalisib can be decreased when combined with Ribociclib.
Brodalumab Injection Brodalumab Injection The risk or severity of adverse effects can be increased when Idelalisib is combined with Brodalumab.
Brigatinib Brigatinib The metabolism of Idelalisib can be increased when combined with Brigatinib.
Deflazacort Deflazacort The metabolism of Deflazacort can be increased when combined with Idelalisib.
Safinamide Safinamide Safinamide may decrease the excretion rate of Idelalisib which could result in a higher serum level.
Ocrelizumab Injection Ocrelizumab Injection The risk or severity of adverse effects can be increased when Idelalisib is combined with Ocrelizumab.
Sarilumab Injection Sarilumab Injection The metabolism of Sarilumab can be increased when combined with Idelalisib.
Midostaurin Midostaurin The metabolism of Idelalisib can be increased when combined with Midostaurin.
Neratinib Neratinib The metabolism of Idelalisib can be decreased when combined with Neratinib.
Guselkumab Injection Guselkumab Injection The risk or severity of adverse effects can be increased when Idelalisib is combined with Guselkumab.
Enasidenib Enasidenib The metabolism of Idelalisib can be increased when combined with Enasidenib.
Inotuzumab Ozogamicin Injection Inotuzumab Ozogamicin Injection The serum concentration of Idelalisib can be increased when it is combined with Inotuzumab ozogamicin.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Idelalisib can be increased when combined with Fosaprepitant.
Copanlisib Injection Copanlisib Injection The metabolism of Copanlisib can be decreased when combined with Idelalisib.
Abemaciclib Abemaciclib The metabolism of Idelalisib can be decreased when combined with Abemaciclib.
Betrixaban Betrixaban The serum concentration of Betrixaban can be increased when it is combined with Idelalisib.
Acalabrutinib Acalabrutinib The metabolism of Idelalisib can be decreased when combined with Acalabrutinib.
Gemtuzumab Ozogamicin Injection Gemtuzumab Ozogamicin Injection The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Idelalisib.
Letermovir Letermovir The metabolism of Idelalisib can be decreased when combined with Letermovir.
Ertugliflozin Ertugliflozin The serum concentration of Ertugliflozin can be increased when it is combined with Idelalisib.
Buprenorphine Injection Buprenorphine Injection The metabolism of Idelalisib can be decreased when combined with Buprenorphine.
Apalutamide Apalutamide The serum concentration of Idelalisib can be decreased when it is combined with Apalutamide.
Penicillamine Penicillamine The risk or severity of adverse effects can be increased when Penicillamine is combined with Idelalisib.
Fostamatinib Fostamatinib The metabolism of Idelalisib can be decreased when combined with Fostamatinib.
Avatrombopag Avatrombopag Avatrombopag may decrease the excretion rate of Idelalisib which could result in a higher serum level.
Baricitinib Baricitinib The risk or severity of adverse effects can be increased when Idelalisib is combined with Baricitinib.
Eliglustat Eliglustat The metabolism of Eliglustat can be decreased when combined with Idelalisib.
Binimetinib Binimetinib The serum concentration of Binimetinib can be increased when it is combined with Idelalisib.
Ivosidenib Ivosidenib The metabolism of Ivosidenib can be increased when combined with Idelalisib.
Lusutrombopag Lusutrombopag The serum concentration of Lusutrombopag can be increased when it is combined with Idelalisib.
Elagolix Elagolix The serum concentration of Elagolix can be increased when it is combined with Idelalisib.
Cannabidiol Cannabidiol Cannabidiol may decrease the excretion rate of Idelalisib which could result in a higher serum level.
Dacomitinib Dacomitinib The metabolism of Idelalisib can be decreased when combined with Dacomitinib.
Duvelisib Duvelisib The metabolism of Idelalisib can be decreased when combined with Duvelisib.
Omadacycline Omadacycline The serum concentration of Omadacycline can be increased when it is combined with Idelalisib.
Sarecycline Sarecycline The serum concentration of Idelalisib can be increased when it is combined with Sarecycline.
Stiripentol Stiripentol The metabolism of Idelalisib can be decreased when combined with Stiripentol.
Talazoparib Talazoparib The serum concentration of Talazoparib can be increased when it is combined with Idelalisib.
Gilteritinib Gilteritinib The metabolism of Idelalisib can be decreased when combined with Gilteritinib.
Glasdegib Glasdegib The serum concentration of Glasdegib can be increased when it is combined with Idelalisib.
Larotrectinib Larotrectinib The serum concentration of Larotrectinib can be increased when it is combined with Idelalisib.
Methoxy Polyethylene Glycol-Epoetin Beta Injection Methoxy Polyethylene Glycol-Epoetin Beta Injection The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Idelalisib.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Idelalisib can be increased when combined with Paclitaxel.
Rifamycin Rifamycin The metabolism of Idelalisib can be increased when combined with Rifamycin.
Prucalopride Prucalopride The metabolism of Prucalopride can be decreased when combined with Idelalisib.
Ravulizumab-cwvz Injection Ravulizumab-cwvz Injection The risk or severity of adverse effects can be increased when Idelalisib is combined with Ravulizumab.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Emapalumab can be increased when combined with Idelalisib.
Siponimod Siponimod The risk or severity of adverse effects can be increased when Idelalisib is combined with Siponimod.
Erdafitinib Erdafitinib The serum concentration of Idelalisib can be increased when it is combined with Erdafitinib.
Risankizumab-rzaa Injection Risankizumab-rzaa Injection The risk or severity of adverse effects can be increased when Idelalisib is combined with Risankizumab.
Alpelisib Alpelisib The metabolism of Idelalisib can be increased when combined with Alpelisib.
Cladribine Cladribine The risk or severity of adverse effects can be increased when Cladribine is combined with Idelalisib.
Darolutamide Darolutamide The serum concentration of Idelalisib can be increased when it is combined with Darolutamide.
Triclabendazole Triclabendazole The metabolism of Idelalisib can be decreased when combined with Triclabendazole.
Entrectinib Entrectinib The metabolism of Idelalisib can be decreased when combined with Entrectinib.
Pexidartinib Pexidartinib Idelalisib may increase the hepatotoxic activities of Pexidartinib.
Istradefylline Istradefylline The serum concentration of Idelalisib can be increased when it is combined with Istradefylline.
Pitolisant Pitolisant The serum concentration of Idelalisib can be decreased when it is combined with Pitolisant.
Fedratinib Fedratinib The serum concentration of Fedratinib can be increased when it is combined with Idelalisib.
Lefamulin Lefamulin The serum concentration of Idelalisib can be increased when it is combined with Lefamulin.
Phenytoin Injection Phenytoin Injection The metabolism of Idelalisib can be increased when combined with Phenytoin.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Idelalisib can be increased when combined with Fosphenytoin.
Enfortumab vedotin-ejfv Injection Enfortumab vedotin-ejfv Injection The serum concentration of Enfortumab vedotin can be increased when it is combined with Idelalisib.
Zanubrutinib Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Idelalisib.
Voxelotor Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Idelalisib.
Lumateperone Lumateperone The serum concentration of Lumateperone can be increased when it is combined with Idelalisib.
Lasmiditan Lasmiditan The serum concentration of Idelalisib can be increased when it is combined with Lasmiditan.
Ubrogepant Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Idelalisib.
Tazemetostat Tazemetostat The metabolism of Idelalisib can be decreased when combined with Tazemetostat.
Bempedoic Acid Bempedoic Acid The excretion of Bempedoic acid can be decreased when combined with Idelalisib.
Cenobamate Cenobamate The serum concentration of Idelalisib can be decreased when it is combined with Cenobamate.
Ozanimod Ozanimod The risk or severity of adverse effects can be increased when Idelalisib is combined with Ozanimod.
Selumetinib Selumetinib The serum concentration of Selumetinib can be increased when it is combined with Idelalisib.
Rimegepant Rimegepant The serum concentration of Rimegepant can be increased when it is combined with Idelalisib.
Tucatinib Tucatinib Idelalisib may decrease the excretion rate of Tucatinib which could result in a higher serum level.
Remdesivir Injection Remdesivir Injection The serum concentration of Remdesivir can be increased when it is combined with Idelalisib.
Ripretinib Ripretinib Ripretinib may decrease the excretion rate of Idelalisib which could result in a higher serum level.
Selpercatinib Selpercatinib The serum concentration of Selpercatinib can be increased when it is combined with Idelalisib.
Capmatinib Capmatinib The serum concentration of Idelalisib can be increased when it is combined with Capmatinib.
Lemborexant Lemborexant The serum concentration of Lemborexant can be increased when it is combined with Idelalisib.
Fostemsavir Fostemsavir Fostemsavir may decrease the excretion rate of Idelalisib which could result in a higher serum level.
Octreotide Octreotide The serum concentration of Idelalisib can be increased when it is combined with Octreotide.
Belantamab Mafodotin-blmf Injection Belantamab Mafodotin-blmf Injection The serum concentration of Belantamab mafodotin can be increased when it is combined with Idelalisib.
Pralsetinib Pralsetinib The metabolism of Idelalisib can be increased when combined with Pralsetinib.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Idelalisib can be decreased when it is combined with Satralizumab.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Idelalisib can be decreased when combined with Drospirenone.
Vitamin E (Alpha-Tocopherol) Vitamin E (Alpha-Tocopherol) The metabolism of Idelalisib can be increased when combined with Vitamin E.
Theophylline Theophylline The metabolism of Theophylline can be decreased when combined with Idelalisib.
Indomethacin Indomethacin The risk or severity of adverse effects can be increased when Indomethacin is combined with Idelalisib.
Hydroxyurea Hydroxyurea The risk or severity of adverse effects can be increased when Hydroxyurea is combined with Idelalisib.
Floxuridine Floxuridine The risk or severity of adverse effects can be increased when Floxuridine is combined with Idelalisib.
Phenobarbital Phenobarbital The metabolism of Idelalisib can be increased when combined with Phenobarbital.
Methotrexate Injection Methotrexate Injection The risk or severity of adverse effects can be increased when Idelalisib is combined with Methotrexate.
Primidone Primidone The metabolism of Idelalisib can be increased when combined with Primidone.
Chlorpromazine Chlorpromazine The metabolism of Idelalisib can be increased when combined with Chlorpromazine.
Diazepam Diazepam The metabolism of Idelalisib can be decreased when combined with Diazepam.
Lorazepam Lorazepam The metabolism of Idelalisib can be decreased when combined with Lorazepam.
Carmustine Carmustine The risk or severity of adverse effects can be increased when Carmustine is combined with Idelalisib.
Bromocriptine Bromocriptine The metabolism of Idelalisib can be decreased when combined with Bromocriptine.
Tranylcypromine Tranylcypromine The metabolism of Idelalisib can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Idelalisib can be decreased when combined with Phenelzine.
Procarbazine Procarbazine The risk or severity of adverse effects can be increased when Procarbazine is combined with Idelalisib.
Tetracycline Tetracycline The metabolism of Idelalisib can be decreased when combined with Tetracycline.
Thioguanine Thioguanine The risk or severity of adverse effects can be increased when Tioguanine is combined with Idelalisib.
Prochlorperazine Prochlorperazine The metabolism of Idelalisib can be decreased when combined with Prochlorperazine.
Trifluoperazine Trifluoperazine The metabolism of Trifluoperazine can be decreased when combined with Idelalisib.
Bleomycin Bleomycin The risk or severity of adverse effects can be increased when Bleomycin is combined with Idelalisib.
Methadone Methadone The metabolism of Idelalisib can be increased when combined with Methadone.
Oxybutynin Oxybutynin The metabolism of Idelalisib can be decreased when combined with Oxybutynin.
Orphenadrine Orphenadrine The metabolism of Idelalisib can be decreased when combined with Orphenadrine.
Azathioprine Azathioprine The risk or severity of adverse effects can be increased when Azathioprine is combined with Idelalisib.
Phentermine Phentermine The metabolism of Idelalisib can be decreased when combined with Phentermine.
Sulfasalazine Sulfasalazine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Idelalisib.
Hydrocortisone Hydrocortisone The metabolism of Idelalisib can be increased when combined with Hydrocortisone.
Lomustine Lomustine The risk or severity of adverse effects can be increased when Lomustine is combined with Idelalisib.
Doxorubicin Doxorubicin The metabolism of Idelalisib can be decreased when combined with Doxorubicin.
Cytarabine Cytarabine The risk or severity of adverse effects can be increased when Idelalisib is combined with Cytarabine.
Mechlorethamine Mechlorethamine The risk or severity of adverse effects can be increased when Mechlorethamine is combined with Idelalisib.
Dactinomycin Dactinomycin The risk or severity of adverse effects can be increased when Dactinomycin is combined with Idelalisib.
Carbamazepine Carbamazepine The metabolism of Idelalisib can be increased when combined with Carbamazepine.
Clonidine Clonidine The metabolism of Clonidine can be decreased when combined with Idelalisib.
Hydralazine Hydralazine The metabolism of Idelalisib can be decreased when combined with Hydralazine.
Cimetidine Cimetidine The metabolism of Idelalisib can be decreased when combined with Cimetidine.
Warfarin Warfarin The serum concentration of Warfarin can be increased when it is combined with Idelalisib.
Loperamide Loperamide The metabolism of Idelalisib can be decreased when combined with Loperamide.
Daunorubicin Daunorubicin The metabolism of Idelalisib can be decreased when combined with Daunorubicin.
Griseofulvin Griseofulvin The metabolism of Idelalisib can be increased when combined with Griseofulvin.
Digoxin Digoxin The serum concentration of Digoxin can be increased when it is combined with Idelalisib.
Loxapine Loxapine The serum concentration of Idelalisib can be increased when it is combined with Loxapine.
Quinine Quinine The metabolism of Idelalisib can be increased when combined with Quinine.
Calcitriol Calcitriol The metabolism of Idelalisib can be increased when combined with Calcitriol.
Sulfinpyrazone Sulfinpyrazone The metabolism of Idelalisib can be increased when combined with Sulfinpyrazone.
Clindamycin Injection Clindamycin Injection The metabolism of Clindamycin can be decreased when combined with Idelalisib.
Secobarbital Secobarbital The metabolism of Idelalisib can be increased when combined with Secobarbital.
Desipramine Desipramine The metabolism of Idelalisib can be decreased when combined with Desipramine.
Imipramine Imipramine The serum concentration of Imipramine can be increased when it is combined with Idelalisib.
Probenecid Probenecid The metabolism of Idelalisib can be increased when combined with Probenecid.
Quinidine Quinidine The metabolism of Idelalisib can be decreased when combined with Quinidine.
Isoniazid Isoniazid The metabolism of Idelalisib can be decreased when combined with Isoniazid.
Rifampin Rifampin The metabolism of Idelalisib can be increased when combined with Rifampicin.
Valproic Acid Valproic Acid The metabolism of Idelalisib can be decreased when combined with Valproic acid.
Tamoxifen Tamoxifen The metabolism of Idelalisib can be increased when combined with Tamoxifen.
Mitomycin Mitomycin The risk or severity of adverse effects can be increased when Mitomycin is combined with Idelalisib.
Liothyronine Liothyronine The excretion of Liothyronine can be decreased when combined with Idelalisib.
Methimazole Methimazole The metabolism of Idelalisib can be decreased when combined with Methimazole.
Propylthiouracil Propylthiouracil The risk or severity of adverse effects can be increased when Propylthiouracil is combined with Idelalisib.
Dinoprostone Dinoprostone The excretion of Dinoprostone can be decreased when combined with Idelalisib.
Niacin Niacin The metabolism of Idelalisib can be decreased when combined with Niacin.
Danazol Danazol The metabolism of Idelalisib can be decreased when combined with Danazol.
Nortriptyline Nortriptyline The metabolism of Nortriptyline can be decreased when combined with Idelalisib.
Amphotericin B Injection Amphotericin B Injection The metabolism of Idelalisib can be decreased when combined with Amphotericin B.
Mercaptopurine Mercaptopurine The risk or severity of adverse effects can be increased when Mercaptopurine is combined with Idelalisib.
Clomiphene Clomiphene The serum concentration of Idelalisib can be increased when it is combined with Clomifene.
Fluorouracil Injection Fluorouracil Injection The risk or severity of adverse effects can be increased when Fluorouracil is combined with Idelalisib.
Colchicine Colchicine The metabolism of Colchicine can be decreased when combined with Idelalisib.
Cephalexin Cephalexin The metabolism of Idelalisib can be decreased when combined with Cephalexin.
Dacarbazine Dacarbazine The risk or severity of adverse effects can be increased when Dacarbazine is combined with Idelalisib.
Acetazolamide Acetazolamide The metabolism of Idelalisib can be decreased when combined with Acetazolamide.
Bacillus Calmette-Guerin (BCG) Vaccine Bacillus Calmette-Guerin (BCG) Vaccine The risk or severity of infection can be increased when Bacillus calmette-guerin substrain tice live antigen is combined with Idelalisib.
Ketoconazole Ketoconazole The metabolism of Idelalisib can be decreased when combined with Ketoconazole.
Thiotepa Injection Thiotepa Injection The risk or severity of adverse effects can be increased when Idelalisib is combined with Thiotepa.
Vincristine Injection Vincristine Injection The risk or severity of adverse effects can be increased when Idelalisib is combined with Vincristine.
Vinblastine Vinblastine The metabolism of Idelalisib can be increased when combined with Vinblastine.
Metoprolol Metoprolol The metabolism of Idelalisib can be decreased when combined with Metoprolol.
Hydroxyzine Hydroxyzine The metabolism of Hydroxyzine can be decreased when combined with Idelalisib.
Chlorambucil Chlorambucil The risk or severity of adverse effects can be increased when Chlorambucil is combined with Idelalisib.
Alprazolam Alprazolam The metabolism of Alprazolam can be decreased when combined with Idelalisib.
Diltiazem Diltiazem The metabolism of Idelalisib can be decreased when combined with Diltiazem.
Nifedipine Nifedipine The metabolism of Idelalisib can be increased when combined with Nifedipine.
Verapamil Verapamil The metabolism of Idelalisib can be decreased when combined with Verapamil.
Cisplatin Injection Cisplatin Injection The risk or severity of adverse effects can be increased when Cisplatin is combined with Idelalisib.
Streptozocin Streptozocin The risk or severity of adverse effects can be increased when Streptozocin is combined with Idelalisib.
Etoposide Etoposide The metabolism of Idelalisib can be increased when combined with Etoposide.
Glyburide Glyburide The metabolism of Idelalisib can be decreased when combined with Glyburide.
Dicloxacillin Dicloxacillin The metabolism of Idelalisib can be increased when combined with Dicloxacillin.
Nafcillin Injection Nafcillin Injection The metabolism of Idelalisib can be increased when combined with Nafcillin.
Pimozide Pimozide The metabolism of Idelalisib can be decreased when combined with Pimozide.
Enalapril Enalapril The excretion of Enalapril can be decreased when combined with Idelalisib.
Amiodarone Amiodarone The metabolism of Idelalisib can be decreased when combined with Amiodarone.
Lovastatin Lovastatin The metabolism of Lovastatin can be decreased when combined with Idelalisib.
Ciprofloxacin Ciprofloxacin The metabolism of Idelalisib can be decreased when combined with Ciprofloxacin.
Interferon Alfa-2b Injection Interferon Alfa-2b Injection The risk or severity of adverse effects can be increased when Interferon alfa-2b is combined with Idelalisib.
Clozapine Clozapine The metabolism of Idelalisib can be increased when combined with Clozapine.
Idarubicin Idarubicin The risk or severity of adverse effects can be increased when Idarubicin is combined with Idelalisib.
Fludarabine Injection Fludarabine Injection The risk or severity of adverse effects can be increased when Fludarabine is combined with Idelalisib.
Pentostatin Injection Pentostatin Injection The risk or severity of adverse effects can be increased when Pentostatin is combined with Idelalisib.
Clarithromycin Clarithromycin The metabolism of Idelalisib can be decreased when combined with Clarithromycin.
Felodipine Felodipine The metabolism of Idelalisib can be decreased when combined with Felodipine.
Pravastatin Pravastatin Pravastatin may decrease the excretion rate of Idelalisib which could result in a higher serum level.
Simvastatin Simvastatin The serum concentration of Idelalisib can be increased when it is combined with Simvastatin.
Epoetin Alfa, Injection Epoetin Alfa, Injection The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Idelalisib.
Teniposide Injection Teniposide Injection The metabolism of Idelalisib can be decreased when combined with Teniposide.
Itraconazole Itraconazole The metabolism of Idelalisib can be decreased when combined with Itraconazole.
Rifabutin Rifabutin The metabolism of Idelalisib can be increased when combined with Rifabutin.
Bisoprolol Bisoprolol The serum concentration of Idelalisib can be increased when it is combined with Bisoprolol.
Doxazosin Doxazosin The metabolism of Idelalisib can be decreased when combined with Doxazosin.
Isradipine Isradipine The metabolism of Idelalisib can be decreased when combined with Isradipine.
Omeprazole Omeprazole The metabolism of Idelalisib can be increased when combined with Omeprazole.
Cisapride Cisapride The metabolism of Idelalisib can be decreased when combined with Cisapride.
Fluvastatin Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Idelalisib.
Venlafaxine Venlafaxine Venlafaxine may increase the excretion rate of Idelalisib which could result in a lower serum level and potentially a reduction in efficacy.
Famciclovir Famciclovir The metabolism of Idelalisib can be decreased when combined with Famciclovir.
Fluvoxamine Fluvoxamine The metabolism of Fluvoxamine can be decreased when combined with Idelalisib.
Nefazodone Nefazodone The metabolism of Idelalisib can be decreased when combined with Nefazodone.
Lamotrigine Lamotrigine The metabolism of Lamotrigine can be decreased when combined with Idelalisib.
Losartan Losartan The metabolism of Idelalisib can be decreased when combined with Losartan.
Tramadol Tramadol The metabolism of Tramadol can be decreased when combined with Idelalisib.
Vinorelbine Injection Vinorelbine Injection The risk or severity of adverse effects can be increased when Idelalisib is combined with Vinorelbine.
Carboplatin Injection Carboplatin Injection The risk or severity of adverse effects can be increased when Carboplatin is combined with Idelalisib.
Lansoprazole Lansoprazole The metabolism of Idelalisib can be increased when combined with Lansoprazole.
Ifosfamide Injection Ifosfamide Injection The metabolism of Idelalisib can be increased when combined with Ifosfamide.
Pegaspargase Injection Pegaspargase Injection The risk or severity of adverse effects can be increased when Pegaspargase is combined with Idelalisib.
Nicardipine Nicardipine The metabolism of Idelalisib can be decreased when combined with Nicardipine.
Ticlopidine Ticlopidine The metabolism of Idelalisib can be decreased when combined with Ticlopidine.
Saquinavir Saquinavir The metabolism of Idelalisib can be decreased when combined with Saquinavir.
Gemcitabine Injection Gemcitabine Injection The risk or severity of adverse effects can be increased when Gemcitabine is combined with Idelalisib.
Ritonavir Ritonavir The serum concentration of Idelalisib can be increased when it is combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The metabolism of Idelalisib can be decreased when combined with Docetaxel.
Clomipramine Clomipramine The metabolism of Clomipramine can be decreased when combined with Idelalisib.
Zafirlukast Zafirlukast The metabolism of Idelalisib can be decreased when combined with Zafirlukast.
Mirtazapine Mirtazapine The metabolism of Idelalisib can be decreased when combined with Mirtazapine.
Topiramate Topiramate The metabolism of Topiramate can be increased when combined with Idelalisib.
Valsartan Valsartan The excretion of Valsartan can be decreased when combined with Idelalisib.
Nelfinavir Nelfinavir Nelfinavir may decrease the excretion rate of Idelalisib which could result in a higher serum level.
Fexofenadine Fexofenadine The serum concentration of Fexofenadine can be increased when it is combined with Idelalisib.
Azithromycin Azithromycin The metabolism of Idelalisib can be decreased when combined with Azithromycin.
Carvedilol Carvedilol The serum concentration of Idelalisib can be increased when it is combined with Carvedilol.
Bicalutamide Bicalutamide The metabolism of Idelalisib can be decreased when combined with Bicalutamide.
Propafenone Propafenone The serum concentration of Idelalisib can be increased when it is combined with Propafenone.
Raloxifene Raloxifene The metabolism of Raloxifene can be decreased when combined with Idelalisib.
Irbesartan Irbesartan The metabolism of Idelalisib can be decreased when combined with Irbesartan.
Paroxetine Paroxetine The metabolism of Idelalisib can be decreased when combined with Paroxetine.
Citalopram Citalopram The metabolism of Idelalisib can be decreased when combined with Citalopram.
Capecitabine Capecitabine The risk or severity of adverse effects can be increased when Capecitabine is combined with Idelalisib.
Efavirenz Efavirenz The metabolism of Idelalisib can be increased when combined with Efavirenz.
Sildenafil Sildenafil The serum concentration of Idelalisib can be increased when it is combined with Sildenafil.
Trastuzumab Injection Trastuzumab Injection Trastuzumab may increase the neutropenic activities of Idelalisib.
Thalidomide Thalidomide The risk or severity of adverse effects can be increased when Thalidomide is combined with Idelalisib.
Rabeprazole Rabeprazole The metabolism of Idelalisib can be decreased when combined with Rabeprazole.
Terbinafine Terbinafine The metabolism of Idelalisib can be increased when combined with Terbinafine.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists

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