Nitrous Oxide
🧬 Where this information comes from Click to expand
The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 46 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →
Nitrous Oxide: frequently asked questions
Common questions about Nitrous Oxide, answered from its official FDA-filed labeling.
Is Nitrous Oxide available over the counter?
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When was Nitrous Oxide first available?
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Who makes Nitrous Oxide?
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Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →
More about Nitrous Oxide on HelloPharmacist
Nitrous Oxide forms and strengths (how it comes)
Nitrous Oxide is available in 1 form. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.
Need a version that does not list lactose, a gluten source, a dye or gelatin? Inactive ingredients differ by manufacturer: see Nitrous Oxide inactive ingredients by manufacturer.
Inhaler
Show 1 more strength Show fewer strengths
Nitrous Oxide on the U.S. market: products, makers and brands
How Nitrous Oxide appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.
42 companies list 44 Nitrous Oxide product records with the FDA, mostly as inhaler; the earliest marketing or approval year on record is 1954. Brand names on the directory include Nitrous Oxide Oxygen Mix; the rest are generics.
Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.
Compare Nitrous Oxide products
A representative set of FDA-listed product records for Nitrous Oxide — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)
| Strength | Route | Manufacturer / Labeler | Category ⓘ | Details |
|---|---|---|---|---|
| 💊Inhaler | ||||
| 990 mL/L | Respiratory (inhalation) | Aero All Gas Company | NDA | View NDC → |
| 990 mL/L | Respiratory (inhalation) | AGL Welding Supply Co., Inc. | NDA | View NDC → |
| 990 mL/L | Respiratory (inhalation) | Agp Llc | NDA | View NDC → |
| 99 L/100 L | Respiratory (inhalation) | Air Source Industries | NDA | View NDC → |
| 99 L/100 L | Respiratory (inhalation) | Airtec Gases, LLC | NDA | View NDC → |
| 990 mL/L | Respiratory (inhalation) | American Welding & Gas | NDA | View NDC → |
| 992 mL/L | Respiratory (inhalation) | Analgesic Services Inc | NDA | View NDC → |
| 99 L/100 L | Respiratory (inhalation) | Badger Welding Supplies, Inc. | NDA | View NDC → |
| 99 L/100 L | Respiratory (inhalation) | Boggs Gases div. Boggs Fire Equipment | UNAPPROVED MEDICAL GAS | View NDC → |
| 990 mL/L | Respiratory (inhalation) | Central Welding Supply Company | NDA | View NDC → |
| 99 L/100 L | Respiratory (inhalation) | Corrigan Propane LLC dba Blue Water Industrial Products | NDA | View NDC → |
| 99 L/100 L | Respiratory (inhalation) | Crumpton Welding Supply & Equipment, Inc. | NDA | View NDC → |
| 990 mL/L | Respiratory (inhalation) | DJB Gas Services, Inc | NDA | View NDC → |
| 990 mL/L | Respiratory (inhalation) | DuPuy Oxygen & Supply Company, Inc. | NDA | View NDC → |
| 990 mL/L | Respiratory (inhalation) | Fullerton Welding Supply | NDA | View NDC → |
| 995 mL/L | Respiratory (inhalation) | General Air Service & Supply Co | NDA | View NDC → |
| 990 mL/L | Respiratory (inhalation) | General Welding Supply Corp. | NDA | View NDC → |
| 995 mL/L | Respiratory (inhalation) | Helget Gas Products | NDA | View NDC → |
| 99 kg/100 kg | Respiratory (inhalation) | Holston Gases, Inc | NDA | View NDC → |
| 990 mL/L | Respiratory (inhalation) | ILMO Products Company | NDA | View NDC → |
| 99 L/100 L | Respiratory (inhalation) | Keen Compressed Gas Co. Inc. | NDA | View NDC → |
| 990 mL/L | Respiratory (inhalation) | Lessors, Incorporated | NDA | View NDC → |
| 990 mL/L | Respiratory (inhalation) | Linde Gas & Equipment Inc. | NDA | View NDC → |
| 990 mL/L | Respiratory (inhalation) | Machine & Welding Supply Company dba Arc3 Gases South | NDA | View NDC → |
| 992 mL/L | Respiratory (inhalation) | Matheson Tri-Gas, Inc. | NDA | View NDC → |
| 990 mL/L | Respiratory (inhalation) | Maverick Oxygen & Respiratory Equipment, Llc | NDA | View NDC → |
| 995 mL/L | Respiratory (inhalation) | Medical-technical Gases, Inc. | NDA | View NDC → |
| 990 mL/L | Respiratory (inhalation) | Metro Welding Supply Corporation | NDA | View NDC → |
| 990 mL/L | Respiratory (inhalation) | MITCHELL WELDING SUPPLY DBA Meritus Texas | NDA | View NDC → |
| 990 mL/L | Respiratory (inhalation) | Nexair, Llc | NDA | View NDC → |
| 990 mL/L | Respiratory (inhalation) | Nitrous Oxide | NDA | View NDC → |
| 900 mL/L | Respiratory (inhalation) | Nitrous Oxide of Canada | NDA | View NDC → |
| 99 L/100 L | Respiratory (inhalation) | Norco, Inc | NDA | View NDC → |
| 990 mL/L | Respiratory (inhalation) | Oxarc, LLC | NDA | View NDC → |
| 990 mL/L | Respiratory (inhalation) | Quality Air Products Inc | NDA | View NDC → |
| 992 mL/L | Respiratory (inhalation) | Red Ball Oxygen Co., Inc. | NDA | View NDC → |
| 500 mL/L | Respiratory (inhalation) | Roberts Oxygen Company, Inc. | NDA | View NDC → |
| 990 mL/L | Respiratory (inhalation) | Roberts Oxygen Company, Inc. × 2 listings | NDA | View NDC → |
| 99 L/100 L | Respiratory (inhalation) | Spectrum Gas Products, Inc | NDA | View NDC → |
| 99 kg/100 kg | Respiratory (inhalation) | United States Welding, Inc. | NDA | View NDC → |
| 99 L/100 L | Respiratory (inhalation) | Volunteer Welding Supply Inc | NDA | View NDC → |
| 995 mL/L | Respiratory (inhalation) | Westair Gases & Equipment, Inc. | NDA | View NDC → |
| 992 mL/L | Respiratory (inhalation) | Wsm Supplier Llc. | NDA | View NDC → |
Showing 44 of 44 products — FDA National Drug Code Directory. See every product, package size and price: browse all 44 Nitrous Oxide NDCs →
Nitrous Oxide side effects reported to the FDA (FAERS)
After a medicine reaches the market, patients, doctors and drugmakers can send the FDA reports of problems they think may be linked to it. Here’s what’s been reported for Nitrous Oxide — a signal of what to watch for, not proof the drug caused it.
Source: openFDA, from the FDA Adverse Event Reporting System (FAERS). These are voluntary reports — they don’t prove the drug caused the effect, and counts reflect how often something was reported, not how often it actually happens. Reports also often name the very problem the medicine is taken for — a common reason to file one is that the drug didn’t help — so for a pain reliever you may see “pain” high on the list; that points to why the report was filed, not to the drug causing the symptom. This counts every report that lists Nitrous Oxide in any role, so the total runs higher than the FDA’s official dashboard, which counts only cases where the drug is the suspect. For the authoritative figures, see the FDA FAERS Public Dashboard. Always talk to your pharmacist or doctor.
Nitrous Oxide FDA approval history
How Nitrous Oxide went from FDA review to the pharmacy shelf — the key milestones in its regulatory journey.
Source: Drugs@FDA.
Nitrous Oxide recall history
A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.
The FDA’s enforcement reports list no Nitrous Oxide recalls since July 2021.
✅No Nitrous Oxide recalls on record since July 2021Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Oct 8, 2026.
RxNorm Concept Web — From Ingredient to Every Form and Strength
This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.
RxCUI 7486 1 dose form · 5 strengths
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Dose form (SCDF) Gas for Inhalation RxCUI 385093In current FDA listings
Look up RxCUI 7486 in the RxCUI Atlas →
RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.
Nitrous Oxide supply and shortage status
Whether Nitrous Oxide is in short supply in the U.S. right now, plus any shortage history the FDA has on record. A shortage usually reflects a manufacturing or demand issue — not a safety problem with the drug.
Source: openFDA, from the FDA Drug Shortages database.
Nitrous Oxide brand names
Nitrous Oxide is sold under one brand name in the FDA directory — Nitrous Oxide Oxygen Mix. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.
Who makes Nitrous Oxide: manufacturers and labelers
42 companies list Nitrous Oxide products with the FDA. By number of product records, the largest are Roberts Oxygen Company, Inc., AGL Welding Supply Co., Inc., Agp Llc. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.
…and 18 more on the FDA NDC directory.
Nitrous Oxide drug class (RxNorm)
Nitrous Oxide belongs to the Other general anesthetics class.
Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.
Sources for this Nitrous Oxide page
Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.
How this page is built
HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. Mitchell Welding Supply is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →