Home › NDC Lookup › Ingredients › Nitrous Oxide › 55037-0301-01
Nitrous Oxide 992 mL/L Gas, 88.7 l — NDC 55037-0301-01 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

Nitrous Oxide 992 mL/L Gas, 88.7 l — NDC 55037-301-01 (Billing 55037-0301-01)

by Matheson Tri-Gas, Inc. · 88.7 L in 1 CYLINDER

This is a package of 88.7 l of Nitrous Oxide 992 mL/L Gas from Matheson Tri-Gas, Inc., marketed since Jan 1987 and currently FDA-listed. It is the main listing for this product, which comes in 28 package sizes.

NDC 55037-0301-01
🏷️ FDA NDC (as labeled) 55037-301-01 billing pads the product segment with a zero
This package
Contains88.7 l Pack sizes28 compare ↓
Main listing for product 55037-301 · Also comes in: 246.4 l 55037-301-02 369.6 l 55037-301-03 418.88 l 55037-301-04 517.44 l 55037-301-05 616 l 55037-301-23 640.64 l 55037-301-06 1059.5 l 55037-301-07 1330.5 l 55037-301-08 1453.7 l 55037-301-09 1724.8 l 55037-301-10 2464 l 55037-301-11 3696 l 55037-301-12 3967.04 l 55037-301-14 4928 l 55037-301-15 5790.4 l 55037-301-16 6160 l 55037-301-17 11827 l 55037-301-19 12320 l 55037-301-18 15520 l 55037-301-29 16016 l 55037-301-20 17987.2 l 55037-301-21 24640 l 55037-301-22 90530 l 55037-301-24 100890 l 55037-301-25 107550 l 55037-301-26 123570 l 55037-301-27 142090 l 55037-301-28
Rx only Brand On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 55037-301-01
Product NDC 55037-301
11-digit billing NDC 55037030101
RxCUI 347166
UNII K50XQU1029
Application # NDA209989
SPL Set ID f5f0f2f7-86a2-41f0-a6cd-3b8cb916dedd
DEA schedule Non-controlled
Marketing category NDA
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 1987-01-01
Route RESPIRATORY (INHALATION)
Dosage form GAS
Substance NITROUS OXIDE
Quick answers
  • RxCUI (RxNorm): 347166
Why two NDCs? The FDA registers this code as 55037-301-01 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 55037-0301-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Other general anesthetics class.

Drug family (ATC) Other general anesthetics
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

📗 Our plain-language guide HelloPharmacist
📖 Read our full Nitrous Oxide guide →

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 246.4 l 369.6 l 418.88 l 517.44 l 616 l 640.64 l 1059.5 l 1330.5 l 1453.7 l 1724.8 l 2464 l 3696 l 3967.04 l 4928 l 5790.4 l 6160 l 11827 l 12320 l 15520 l 16016 l 17987.2 l 24640 l 90530 l 100890 l 107550 l 123570 l 142090 l
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
55037-0301-01 You're viewing this Main listing 88.7 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-02 55037-301-02 246.4 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-03 55037-301-03 369.6 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-04 55037-301-04 418.88 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-05 55037-301-05 517.44 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-06 55037-301-06 640.64 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-07 55037-301-07 1059.5 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-08 55037-301-08 1330.5 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-09 55037-301-09 1453.7 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-10 55037-301-10 1724.8 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-11 55037-301-11 2464 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-12 55037-301-12 3696 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-14 55037-301-14 3967.04 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-15 55037-301-15 4928 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-16 55037-301-16 5790.4 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-17 55037-301-17 6160 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-18 55037-301-18 12320 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-19 55037-301-19 11827 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-20 55037-301-20 16016 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-21 55037-301-21 17987.2 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-22 55037-301-22 24640 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-23 55037-301-23 616 L in 1 CYLINDER 1987-01-01 — Active
55037-0301-24 55037-301-24 90530 L in 1 CONTAINER 1987-01-01 — Active
55037-0301-25 55037-301-25 100890 L in 1 CONTAINER 1987-01-01 — Active
55037-0301-26 55037-301-26 107550 L in 1 CONTAINER 1987-01-01 — Active
55037-0301-27 55037-301-27 123570 L in 1 CONTAINER 1987-01-01 — Active
55037-0301-28 55037-301-28 142090 L in 1 CONTAINER 1987-01-01 — Active
55037-0301-29 55037-301-29 15520 L in 1 TANK 1987-01-01 — Active

Pack size FAQ

What quantity is in this package?
This package contains 88.7 l — 88.7 l in 1 cylinder.
How does this package differ from NDC 55037-0301-02?
Both are Nitrous Oxide 992 mL/L Gas — the drug itself is identical. This page's package is the 88.7 l one, while NDC 55037-0301-02 is the 246.4 l package.
What NDC number is used to bill for this package of Nitrous Oxide 992 mL/L Gas?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Nitrous Oxide 992 mL/L 11054-0007-01 AIRGAS 185 l — — Discontinued —
Nitrous Oxide 992 mL/L 46362-0003-01 Red 300 l — — FDA listed —
Nitrous Oxide 992 mL/L 52085-0003-01 Analgesic 1745 l — — FDA listed —
Nitrous Oxide 992 mL/Lthis 55037-0301-01 Matheson 88.7 l — — FDA listed —
Oxygen 992 mL/L 56130-0004-01 All 1745 l — — FDA listed —
Nitrous Oxide 992 mL/L 84120-0003-01 WSM 1337 l — — FDA listed —
About this product: this is the brand-name version. We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
1987
On the market since
Jan 1987
📍
2026
Currently FDA-listed
39 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

A current SPL was checked, but it does not contain a structured or narrative inactive-ingredient list for this product. This does not mean the product has no inactive ingredients.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerMatheson Tri-Gas, Inc.
FDA applicationNDA209989 (NDA)
Labeler code55037
First marketedJan 1987
Product typeHuman Prescription Drug
Portfolio27 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

Full prescribing information FDA SPL

The complete FDA label for this product — the official prescribing information, verbatim, section by section. Very long sections are excerpted here and marked; the full text is on DailyMed (linked in the sources below). Jump with a chip, search within the label, or expand everything.
📄 Package Label / Principal Display Panel
📄 Package Label / Principal Display Panel ~3 min read ▾

NITROUS OXIDE USP UN1070 DO NOT REMOVE THIS PRODUCT LABEL. CONTENT: LITERS: CU. FT.: Rx only.

WARNING: Administration of Nitrous Oxide may be hazardous or contraindicated. For use only by or under the supervision of a licensed practitioner who is experienced in the use and administration of Nitrous Oxide and is familiar with the indications, effects, dosages, methods, and frequency and duration of administration, and with the hazards, contraindications and side effects, and the precautions to be taken. DANGER: MAY CAUSE OR INTENSIFY FIRE; OXIDIZER.

CONTAINS GAS UNDER PRESSURE; MAY EXPLODE IF HEATED. MAY CAUSE DROWSINESS OR DIZZINESS. MAY DISPLACE OXYGEN AND CAUSE RAPID SUFFOCATION.

MAY CAUSE FROSTBITE. Do not handle until all safety precautions have been read and understood. Keep and store away from clothing and other combustible materials.

Keep valves and fittings free from grease and oil. Avoid breathing gas. Do not get in eyes, on skin, or on clothing.

Use and store only outdoors or in a well-ventilated place. Wear protective gloves, protective clothing, and either eye or face protection. In case of fire: Stop leak if safe to do so.

Store locked up. Dispose of contents/container in accordance with container supplier/owner instructions. Use a back flow preventive device in the piping.

Close valve after each use and when empty. Use only with equipment rated for cylinder pressure. Do not open valve until connected to equipment prepared for use.

Use only equipment of compatible materials of construction. Open valve slowly. Use only with equipment cleaned for oxygen service.

Protect from sunlight when ambient temperature exceeds 52 C (125 F). Read and follow the Matheson Tri-Gas Safety Data Sheet (SDS) before use. FIRST AID: IF INHALED: Remove person to fresh air and keep comfortable for breathing.

Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Thaw frosted parts with lukewarm water. Do not rub affected area.

Get immediate medical advice/attention. CAS: 10024-97-2 WARNING: This product can expose you to chemicals including Nitrous Oxide, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

MATHESON The Gas Professionals MATHESON TRI-GAS 909 LAKE CAROLYN PKWY. SUITE 1300 IRVING, TEXAS 75039 . 1-800-416-2505 nitrous oxide one irving

REFRIGERATED LIQUID NITROUS OXIDE, REFRIGERATED LIQUID USP UN2201 Rx ONLY WARNING: Administration of Nitrous Oxide may be hazardous or contraindicated. For use only by or under the supervision of a licensed practitioner who is experienced in the use and administration of Nitrous Oxide and is familiar with the indications, effects, dosages, methods, and frequency and duration of administration and with the hazards, contraindications and side effects, and the precautions to be taken. DANGER: MAY CAUSE OR INTENSIFY FIRE; OXIDIZER.

CONTAINS REFRIGERATED GAS; MAY CAUSE CRYOGENIC BURNS OR INJURY. MAY CAUSE DROWSINESS OR DIZZINESS. MAY DISPLACE OXYGEN AND CAUSE RAPID SUFFOCATION.

COMBUSTIBLES IN CONTACT WITH OXIDIZING REFRIGERATED LIQUIDS MAY EXPLODE ON IGNITION OR IMPACT. Do not handle until all safety precautions have been read and understood. Keep and store away from clothing and other combustible materials.

Keep valves and fittings free from grease and oil. Avoid breathing gas. Use and store only outdoors or in a well-ventilated place.

Wear cold insulating gloves, face shield, and eye protection. In case of fire: Stop leak if safe to do so. Store locked up.

Dispose of contents/container in accordance with container supplier/owner instructions. Use a back flow preventive device in the piping. Do not open valve until connected to equipment prepared for use.

Use only equipment of compatible materials of construction. Open valve slowly. Use only equipment cleaned for oxygen service.

Always keep container in upright position. DO NOT change or force fit connections. Avoid spills.

Do not walk on… [Excerpted — this section continues on DailyMed.]

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

About this NDC listing & data coverage

Finished prescription product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Matheson Tri-Gas, Inc.. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 27 other package presentations of this same product, including 246.4 l (55037-0301-02), 369.6 l (55037-0301-03), 418.88 l (55037-0301-04). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Matheson Tri-Gas, Inc. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as a prescription product, so it is dispensed under a prescriber's order. Your pharmacist can tell you whether any over-the-counter forms of the same medication exist.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 55037-0201-01 · Matheson 55037-0302-01 · Matheson →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.