Inactive ingredients by manufacturer

Sofosbuvir inactive ingredients by manufacturer

Wondering whether your Sofosbuvir has lactose, gluten, soy, a dye or gelatin in it? The medicine is the same, but the fillers, coatings and colors differ from one company to the next. This page shows what each Sofosbuvir product's FDA label lists, so you can find a version that leaves out what you avoid and ask your pharmacist for it by its NDC.

We have read the FDA labels of 4 of the 4 current Sofosbuvir products on the market today, from 1 company listing it with the FDA, and lined them up side by side.

Dr. Brian Staiger, PharmD, BCPS
Curated and coded by Dr. Brian Staiger, PharmD, BCPS, clinical pharmacist. The ingredient groups this page checks for (what counts as a gluten source, a synthetic dye, soy and so on) are his classification; the lists themselves are the manufacturers' own FDA labels. Updated October 6, 2026. Rebuilt daily from the FDA directory; labels re-read when the FDA publishes a new version.

Ask about your bottle

Is there something in your Sofosbuvir? Ask in plain words.

Name the company, strength or the NDC on your bottle and the ingredient you avoid. The answer comes only from the FDA labels on this page.

Answers are drawn from the FDA label data on this page and checked against it. They are not medical advice: confirm with your pharmacist before relying on them.

The short answer

Which Sofosbuvir products list lactose, a gluten source, soy, dyes or gelatin?

  1. LactoseDiffers by manufacturer

    2 of 4 checked products list lactose; 2 do not. See which products do not list it

  2. Wheat or gluten sourceNo checked product

    No checked Sofosbuvir product lists a wheat or gluten source.

  3. SoyNo checked product

    No checked Sofosbuvir product lists soy.

  4. Synthetic dyesNo checked product

    No checked Sofosbuvir product lists synthetic dyes.

  5. GelatinNo checked product

    No checked Sofosbuvir product lists gelatin.

Also listed by some products: Titanium dioxide 2 of 4 PEG or polysorbate 4 of 4 Sorbitol or mannitol 2 of 4

Find a version without it

Every current Sofosbuvir product and what its label lists

Hide products that list:

Sofosbuvir 150 mg other oral form 1 company Lactose 1 Polyethylene glycol or polysorbate 1
CompanyListsInactive ingredients on the label
Gilead SciencesNDC 61958-1504-01 Lactose Polyethylene glycol or polysorbate
Show 13 ingredients

CROSCARMELLOSE SODIUM, DIMETHYLAMINOETHYL METHACRYLATE - BUTYL METHACRYLATE - METHYL METHACRYLATE COPOLYMER, HYDROXYPROPYL CELLULOSE, UNSPECIFIED, HYPROMELLOSE, UNSPECIFIED, LACTOSE MONOHYDRATE, MICROCRYSTALLINE CELLULOSE, POLYETHYLENE GLYCOL, UNSPECIFIED, SILICON DIOXIDE, SODIUM LAURYL SULFATE, SODIUM STEARYL FUMARATE, STEARIC ACID, TALC, WATER
Sofosbuvir 200 mg other oral form 1 company Lactose 1 Polyethylene glycol or polysorbate 1
CompanyListsInactive ingredients on the label
Gilead SciencesNDC 61958-1505-01 Lactose Polyethylene glycol or polysorbate
Show 13 ingredients

CROSCARMELLOSE SODIUM, DIMETHYLAMINOETHYL METHACRYLATE - BUTYL METHACRYLATE - METHYL METHACRYLATE COPOLYMER, HYDROXYPROPYL CELLULOSE, UNSPECIFIED, HYPROMELLOSE, UNSPECIFIED, LACTOSE MONOHYDRATE, MICROCRYSTALLINE CELLULOSE, POLYETHYLENE GLYCOL, UNSPECIFIED, SILICON DIOXIDE, SODIUM LAURYL SULFATE, SODIUM STEARYL FUMARATE, STEARIC ACID, TALC, WATER
Sofosbuvir 200 mg tablet 1 company Titanium dioxide 1 Polyethylene glycol or polysorbate 1 Sorbitol or mannitol 1
CompanyListsInactive ingredients on the label
Gilead SciencesNDC 61958-1503-01 Titanium dioxide Polyethylene glycol or polysorbate Sorbitol or mannitol
Show 11 ingredients

CROSCARMELLOSE SODIUM, FERRIC OXIDE YELLOW, MAGNESIUM STEARATE, MANNITOL, MICROCRYSTALLINE CELLULOSE, POLYETHYLENE GLYCOL, UNSPECIFIED, POLYVINYL ALCOHOL, UNSPECIFIED, SILICON DIOXIDE, TALC, TITANIUM DIOXIDE, WATER
Sofosbuvir 400 mg tablet 1 company Titanium dioxide 1 Polyethylene glycol or polysorbate 1 Sorbitol or mannitol 1
CompanyListsInactive ingredients on the label
Gilead SciencesNDC 61958-1501-01 Titanium dioxide Polyethylene glycol or polysorbate Sorbitol or mannitol
Show 11 ingredients

CROSCARMELLOSE SODIUM, FERRIC OXIDE YELLOW, MAGNESIUM STEARATE, MANNITOL, MICROCRYSTALLINE CELLULOSE, POLYETHYLENE GLYCOL, UNSPECIFIED, POLYVINYL ALCOHOL, UNSPECIFIED, SILICON DIOXIDE, TALC, TITANIUM DIOXIDE, WATER

A product with none of these listed is not certified to be without them: the label says what the manufacturer declared, and the source of a starch or a flavor is often not stated. The companies are the FDA's labelers, which include repackagers and distributors selling another company's product under their own label. The NDC opens the product's own page, with the full label and its inactive-ingredient notes.

Sofosbuvir without lactose

Lactose: milk sugar; a concern with lactose intolerance or a milk allergy. 2 of 4 checked products list lactose; 2 do not.

Show which Sofosbuvir products list lactose and which do not, by product and company

Does not list lactose

Lists lactose

Sofosbuvir without titanium dioxide

Titanium dioxide: A white colorant some people choose to avoid. 2 of 4 checked products list titanium dioxide; 2 do not.

Show which Sofosbuvir products list titanium dioxide and which do not, by product and company

Does not list titanium dioxide

Lists titanium dioxide

Sofosbuvir and polyethylene glycol or polysorbate

Polyethylene glycol or polysorbate: PEG, macrogol or polysorbate; a rare cause of allergic reactions. Every checked Sofosbuvir product (4) lists polyethylene glycol or polysorbate.

Show which Sofosbuvir products list polyethylene glycol or polysorbate and which do not, by product and company

Lists polyethylene glycol or polysorbate

Sofosbuvir without sorbitol or mannitol

Sorbitol or mannitol: sugar alcohols that can cause bloating or diarrhea in larger amounts. 2 of 4 checked products list sorbitol or mannitol; 2 do not.

Show which Sofosbuvir products list sorbitol or mannitol and which do not, by product and company

Does not list sorbitol or mannitol

Lists sorbitol or mannitol

At the pharmacy counter

How to use this at the pharmacy counter

  1. Pick the company whose list suits you and copy the NDC from the table. Many pharmacies order from wholesalers that carry several companies' versions and can request a particular one if you ask before the prescription is filled; some buy from one contracted source only, and a few insurance plans cover only certain NDCs, so ask the pharmacist to check.
  2. Treat "does not list" as exactly that. The label is what the manufacturer declared; a flavor or a starch may have an unstated source, and lines change. For celiac disease or a serious allergy, ask the manufacturer's medical information line for a written statement about the lot you have.
  3. Check the bottle each refill. A different company usually means a different shape, color and inactive-ingredient list; the pharmacist can tell you who made it, and the two-NDC comparison shows the difference line by line.
  4. If you need one company's version kept constant, ask your prescriber to write that company or the NDC on the prescription and tell the pharmacy you need it held. Rules vary by state and plan, so confirm with the pharmacist.
Ask Dr. Staiger which Sofosbuvir product suits you →

Common questions about Sofosbuvir inactive ingredients

Is Sofosbuvir gluten-free?
This page cannot certify any Sofosbuvir product gluten-free; it reports what each label declares. Of the 4 products checked, none lists a wheat, barley, rye or gluten ingredient, and none lists a starch without a stated source. If you have celiac disease, ask the manufacturer's medical information line for a written gluten statement for the lot you have.
Does Sofosbuvir contain lactose?
2 of 4 checked Sofosbuvir products list lactose; 2 do not: Gilead Sciences (200 mg tablet and 400 mg tablet). The lactose in a tablet or capsule is a small amount, but people with a milk allergy or a strong intolerance often prefer a version that does not list it.
Does Sofosbuvir contain soy?
No checked Sofosbuvir product lists a soy ingredient (soybean oil or soy lecithin) on its label. Soy lecithin is the usual form and the amount is small, but people with a soy allergy often prefer a version that does not list it.
Is there a dye-free Sofosbuvir?
No checked Sofosbuvir product lists a synthetic dye (an FD&C or D&C colorant) on its label. Colorants often differ by strength within one company's line, so compare the lists above strength by strength.
Does Sofosbuvir contain gelatin?
No checked Sofosbuvir product lists gelatin on its label. Gelatin is usually bovine or porcine and the label rarely says which; for kosher, halal or vegetarian needs, ask the manufacturer.
Why do the inactive ingredients differ between manufacturers?
A generic must match the brand's active ingredient, strength, dose form and how it is absorbed; its fillers, binders, coatings and colorants are the manufacturer's own choice. That is why one Sofosbuvir product can list lactose and a dye while another from a different company lists neither.
Can my pharmacy give me a specific manufacturer's version?
Often, if you ask before the prescription is filled: many pharmacies order from wholesalers that carry several companies' versions and can request a particular one. Some pharmacies buy a generic from one contracted source only, and a few insurance plans cover only certain NDCs, so ask the pharmacist to check. Give them the NDC from this page; the company name alone is often enough.
How current is this list?
The products are the ones in the FDA's current NDC directory as of October 6, 2026. The list is rebuilt every day, the FDA directory is re-imported every week, and each inactive-ingredient list is the manufacturer's FDA label as our label sync last read it, re-read when the FDA publishes a new version. Formulations change, so check the label on your own bottle and ask your pharmacist if a refill looks different.

Sources: the products are the finished Sofosbuvir products in the FDA's current NDC directory (openFDA), as of October 6, 2026; each inactive-ingredient list is the manufacturer's FDA Structured Product Label via DailyMed, as our label sync last read it. The concern groups are HelloPharmacist's classification of the names the label declares. Educational information only, not medical advice; confirm with your pharmacist before relying on a list. ← Back to the Sofosbuvir guide