FDA-filed SPL labeling · retrieved through openFDA

Streptozocin

Brand name Zanosar
Drug class ⓘ Alkylating Drug
Rx Form 1 Route Intravenous
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 1 clinical label set within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

At a glance
Linked label effectiveJul 28, 2026
AvailabilityRx
Earliest approval/marketing year ⓘ1982
FDA-listed product records ⓘ6
Boxed warningNone found in compared labels
How we combine label and product data →
✓No current FDA shortage listed · checked Sep 25, 2026

📖 Streptozocin: Patient Information Guide

A plain-language walkthrough of Streptozocin — what it treats, how it works, how it’s taken, side effects, warnings and interactions. Tap any section to expand it.

🎯What It Treats▾

Streptozocin is used to treat cancer of the pancreas that has gotten worse or spread to other parts of the body. Streptozocin is in a class of medications called alkylating agents. It works by slowing or stopping the growth of cancer cells in your body.

💊How to Take It▾

Streptozocin comes as a powder to be mixed with liquid and given intravenously (into a vein) by a doctor or nurse in a medical facility. It may be injected once a day for 5 days in row every 6 weeks or it may be injected once a week. The length of treatment depends on how well your body responds to treatment with streptozocin.

Your doctor may need to delay your treatment or adjust your dose if you experience certain side effects. It is important for you to tell your doctor how you are feeling during your treatment with streptozocin injection.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

🍽️Food, Alcohol & Dietary Advice▾

Unless your doctor tells you otherwise, continue your normal diet.

⚠️Warnings & Precautions▾

Before receiving streptozocin,

  • tell your doctor and pharmacist if you are allergic to streptozocin, any other medications, or any of the ingredients in streptozocin injection. Ask your pharmacist for a list of the ingredients.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: certain chemotherapy medications such as carboplatin (Paraplatin), cisplatin (Platinol), cyclophosphamide (Cytoxan, Neosar), or doxorubicin (Adriamycin, Doxil); and phenytoin (Dilantin). Your doctor may need to monitor you carefully for side effects. Many other medications may also interact with streptozocin, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. You should not become pregnant or breast-feed during your treatment with streptozocin. If you become pregnant while receiving streptozocin, call your doctor. Streptozocin may harm the fetus.

  • you should know that streptozocin may make you drowsy or confused. Do not drive a car or operate machinery until you know how this medication affects you.

🤒Side Effects in Detail▾
  • Streptozocin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • diarrhea

    • feeling tired

    • depression

  • Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately or get emergency medical treatment:

    • pain, itching, redness, swelling, blisters, or sores in the place where the medication was injected.

    • nausea

    • vomiting

    • shakiness

    • dizziness or lightheadedness

    • sweating

    • confusion

    • nervousness or irritability

    • sudden changes in behavior or mood

    • headache

    • numbness or tingling around the mouth

    • sudden hunger

    • seizures

    • excessive thirst

    • frequent urination

  • Streptozocin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

🚑If You Take Too Much▾

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

➕Other Uses▾

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

ℹ️Good to Know▾

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

📄 Written from Streptozocin’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Every point is grounded in that labeling — nothing is invented. How we use AI →

13

Supplements & herbs that interact with Streptozocin

13 supplements and herbal products have documented interactions with Streptozocin in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.

Severity mix
  • Major · 2
  • Moderate · 10
  • Minor · 1
Every supplement checked against Streptozocin — ranked by severity The full interaction hub: 2 major · 10 moderate · 1 minor · every one linked to its full report. Check Streptozocin against your exact supplements

Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.

1

Nutrient depletion considerations

Streptozocin has been associated with lower levels of 1 nutrient in the clinical literature. This does not mean a deficiency will occur — it means these may be worth discussing with your pharmacist or healthcare provider, especially with long-term use.

See the full Streptozocin nutrient depletion report

Educational information from a licensed clinical database (Natural Medicines) — not medical advice. Do not start or stop medications or supplements without professional guidance.

❓ Streptozocin: frequently asked questions

Common questions about Streptozocin, answered from its official FDA-filed labeling.

Is Streptozocin available over the counter? ▾
Streptozocin is dispensed by prescription according to its FDA labeling, so it isn't sold over the counter. Your prescriber and pharmacist will determine if it's appropriate for you.
When was Streptozocin first available? ▾
Streptozocin has been available in the United States since at least 1982, based on FDA approval history (Drugs@FDA) and product marketing records.
Who makes Streptozocin? ▾
Streptozocin is supplied by 3 manufacturers listed in the FDA NDC Directory, including Esteve Pharmaceuticals, S.a., Teva Parenteral Medicines, Inc., Pfanstiehl, Inc..

💬 Answers drafted from Streptozocin’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Grounded in that labeling — nothing is made up. How we use AI →

🧰 Keep exploring

💊 How Streptozocin comes

Streptozocin is available in 1 form. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Injection

Into a vein
Brands Zanosar
Available strengths 2 strengths
5 FDA-listed product records ⓘ

📊 Streptozocin across the U.S. market

How Streptozocin appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

1
Dose forms ⓘ
3
Manufacturers
1
Brand names
6
FDA-listed product records ⓘ
1982
First marketed ⓘ

Also listed with the FDA, not a patient dose form: Powder (1) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

Esteve Pharmaceuticals, S.a.50%
Teva Parenteral Medicines, Inc.33%
Pfanstiehl, Inc.17%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

🔍 Compare Streptozocin products

A representative set of FDA-listed product records for Streptozocin — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Strength Route Manufacturer / Labeler Category ⓘ Details
💊Injection
1 g/10 mL Intravenous Esteve Pharmaceuticals, S.a. × 3 listings UNAPPROVED DRUG FOR USE IN DRUG SHORTAGE View NDC →
100 mg/mL Intravenous Teva Parenteral Medicines, Inc. × 2 listings NDA View NDC →
💊Bulk drug substance
1 kg/kg — Pfanstiehl, Inc. BULK INGREDIENT View NDC →

Showing 6 of 6 products — FDA National Drug Code Directory. See every product, package size and price: browse all 6 Streptozocin NDCs →

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Streptozocin RxCUI 10114 1 dose form · 1 strength
  1. Dose form (SCDF) Injection RxCUI 1809089 In current FDA listings
    Clinical drug / strength (SCD) 1000 MG RxCUI 239180

Look up RxCUI 10114 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

🏷️ Sold under these brand names

Zanosar

🏭 Manufacturers & labelers

Esteve Pharmaceuticals, S.a. 3 Teva Parenteral Medicines, Inc. 2 Pfanstiehl, Inc. 1

RxNorm drug class

Streptozocin belongs to the Alkylating Drug class.

Pharmacologic class Alkylating Drug
Drug family (ATC) Nitrosoureas
How it works Alkylating Activity

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

🔬 Where this comes from

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Jul 28, 2026
🏭
Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Streptozocin.
📈
Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
🚨
Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Streptozocin after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
1
NDC products indexed
6
Distinct labelers/manufacturers represented
3
Linked representative label ⓘ
Esteve Pharmaceuticals, S.a.
Linked label effective
Jul 28, 2026
Composite sections available
1
Linked SPL Set ID
f31d3bff-6fc6-c35f-e053-2995a90a596b
Linked SPL Document ID
57a75e6d-34f4-c623-e063-6294a90a1944
Open the linked representative label on DailyMed ↗

How we combine label and product data

HelloPharmacist combines public FDA and NLM records; we don’t author the underlying clinical facts. We identified 1 FDA-filed SPL label set within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. The representative label is the starting point for the displayed reference monograph; the 12 largest stored in-scope SPL records, which may include that representative, are compared section by section, and the longest available version of each section is retained. Forms, routes, brands, labelers, product-listed strengths, and product-record counts are aggregated separately from ingredient-matched FDA NDC Directory records; package records listed above are associated with the linked SPL; and the normalized concept hierarchy comes from NLM RxNorm.

For canonical ingredient pages, bounded product-attributed indication and administration excerpts may be added to the AI evidence, and the generator is instructed to preserve available product, brand, route, and form qualifiers instead of treating one label as universal. Where a section is identified as AI-written, its plain-language text is generated from bounded label evidence. New draft drug pages remain in the admin review queue before first publication. Esteve Pharmaceuticals, S.a. is the representative DailyMed label linked for verification and dates; it is not the sole source used for the page.

This is general education, not medical advice — always consult your doctor or pharmacist about your medications and any medical condition. For the exact wording of the linked representative label, view that label on DailyMed; some displayed composite sections may come from other in-scope SPL labels. Learn how we use AI and our data sources & update cadence.