Streptozocin

Generic name: Pronounced as (strep toe zoe' sin)
Brand names
  • Zanosar®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 07/15/2013

Streptozocin should be given only under the supervision of a doctor with experience in the use of chemotherapy medications.

Streptozocin may cause severe or life-threatening kidney problems. Tell your doctor if you have or have ever had kidney disease. Tell your doctor and pharmacist about all the medications you are taking so they can check whether any of your medications may increase the risk that you will develop kidney problems during your treatment with streptozocin. If you experience any of the following symptoms, call your doctor immediately: decreased urination; swelling of the face, arms, hands, feet, ankles, or lower legs; or unusual tiredness or weakness. Follow your doctor's instruction about drinking fluids during your treatment to help reduce the risk of kidney problems.

Streptozocin can cause a severe decrease in the number of blood cells in your bone marrow. This may cause certain symptoms and may increase the risk that you will develop a serious or life-threatening infection or bleeding. If you experience any of the following symptoms, call your doctor immediately: fever, chills, sore throat, ongoing cough and congestion, or other signs of infection; unusual bleeding or bruising; bloody or black, tarry stools; bloody vomit; or vomiting blood or brown material that resembles coffee grounds.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests before, during, and after your treatment to check your body's response to streptozocin. Your doctor may need to stop or delay your treatment if you experience certain side effects.

Streptozocin has been found to increase the risk of developing cancer in some animals. Talk to your doctor about the risks of receiving streptozocin.

Streptozocin is used to treat cancer of the pancreas that has gotten worse or spread to other parts of the body. Streptozocin is in a class of medications called alkylating agents. It works by slowing or stopping the growth of cancer cells in your body.

Streptozocin comes as a powder to be mixed with liquid and given intravenously (into a vein) by a doctor or nurse in a medical facility. It may be injected once a day for 5 days in row every 6 weeks or it may be injected once a week. The length of treatment depends on how well your body responds to treatment with streptozocin.

Your doctor may need to delay your treatment or adjust your dose if you experience certain side effects. It is important for you to tell your doctor how you are feeling during your treatment with streptozocin injection.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before receiving streptozocin,

  • tell your doctor and pharmacist if you are allergic to streptozocin, any other medications, or any of the ingredients in streptozocin injection. Ask your pharmacist for a list of the ingredients.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: certain chemotherapy medications such as carboplatin (Paraplatin), cisplatin (Platinol), cyclophosphamide (Cytoxan, Neosar), or doxorubicin (Adriamycin, Doxil); and phenytoin (Dilantin). Your doctor may need to monitor you carefully for side effects. Many other medications may also interact with streptozocin, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. You should not become pregnant or breast-feed during your treatment with streptozocin. If you become pregnant while receiving streptozocin, call your doctor. Streptozocin may harm the fetus.

  • you should know that streptozocin may make you drowsy or confused. Do not drive a car or operate machinery until you know how this medication affects you.

Unless your doctor tells you otherwise, continue your normal diet.

  • Streptozocin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • diarrhea

    • feeling tired

    • depression

  • Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately or get emergency medical treatment:

    • pain, itching, redness, swelling, blisters, or sores in the place where the medication was injected.

    • nausea

    • vomiting

    • shakiness

    • dizziness or lightheadedness

    • sweating

    • confusion

    • nervousness or irritability

    • sudden changes in behavior or mood

    • headache

    • numbness or tingling around the mouth

    • sudden hunger

    • seizures

    • excessive thirst

    • frequent urination

  • Streptozocin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Leflunomide Leflunomide The risk or severity of adverse effects can be increased when Streptozocin is combined with Leflunomide.
Aminophylline Aminophylline The metabolism of Aminophylline can be increased when combined with Streptozocin.
Anagrelide Anagrelide The metabolism of Anagrelide can be increased when combined with Streptozocin.
Cilostazol Cilostazol The metabolism of Cilostazol can be increased when combined with Streptozocin.
Clopidogrel Clopidogrel The metabolism of Clopidogrel can be increased when combined with Streptozocin.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The metabolism of Conjugated estrogens can be increased when combined with Streptozocin.
Mycophenolate Mycophenolate The risk or severity of adverse effects can be increased when Streptozocin is combined with Mycophenolic acid.
Prednisone Prednisone The risk or severity of adverse effects can be increased when Streptozocin is combined with Prednisone.
Ranitidine Ranitidine The metabolism of Ranitidine can be increased when combined with Streptozocin.
Tacrolimus Tacrolimus Tacrolimus may increase the immunosuppressive activities of Streptozocin.
Tizanidine Tizanidine The metabolism of Tizanidine can be increased when combined with Streptozocin.
Triamcinolone Triamcinolone The risk or severity of adverse effects can be increased when Streptozocin is combined with Triamcinolone.
Zolmitriptan Zolmitriptan The metabolism of Zolmitriptan can be increased when combined with Streptozocin.
Interferon Beta-1b Injection Interferon Beta-1b Injection The risk or severity of adverse effects can be increased when Interferon beta-1b is combined with Streptozocin.
Interferon Gamma-1b Injection Interferon Gamma-1b Injection The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Streptozocin.
Methylprednisolone Injection Methylprednisolone Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Methylprednisolone.
Metoclopramide Injection Metoclopramide Injection The metabolism of Metoclopramide can be increased when combined with Streptozocin.
Zidovudine Injection Zidovudine Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Zidovudine.
Cyclosporine Cyclosporine Streptozocin may increase the immunosuppressive activities of Cyclosporine.
Enoxaparin Injection Enoxaparin Injection The risk or severity of bleeding can be increased when Enoxaparin is combined with Streptozocin.
Olanzapine Olanzapine The metabolism of Olanzapine can be increased when combined with Streptozocin.
Alosetron Alosetron The metabolism of Alosetron can be increased when combined with Streptozocin.
Hydroxychloroquine Hydroxychloroquine The risk or severity of adverse effects can be increased when Streptozocin is combined with Hydroxychloroquine.
Temozolomide Temozolomide The risk or severity of adverse effects can be increased when Streptozocin is combined with Temozolomide.
Anakinra Anakinra The risk or severity of adverse effects can be increased when Anakinra is combined with Streptozocin.
Linezolid Linezolid The risk or severity of adverse effects can be increased when Streptozocin is combined with Linezolid.
Pentosan Polysulfate Pentosan Polysulfate The risk or severity of bleeding can be increased when Pentosan polysulfate is combined with Streptozocin.
Etanercept Injection Etanercept Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Streptozocin.
Sirolimus Sirolimus The risk or severity of adverse effects can be increased when Streptozocin is combined with Sirolimus.
Epirubicin Epirubicin The risk or severity of adverse effects can be increased when Streptozocin is combined with Epirubicin.
Adalimumab Injection Adalimumab Injection The risk or severity of adverse effects can be increased when Adalimumab is combined with Streptozocin.
Glatiramer Injection Glatiramer Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Glatiramer.
Frovatriptan Frovatriptan The metabolism of Frovatriptan can be increased when combined with Streptozocin.
Darbepoetin Alfa Injection Darbepoetin Alfa Injection The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Streptozocin.
Infliximab Injection Infliximab Injection The risk or severity of adverse effects can be increased when Infliximab is combined with Streptozocin.
Duloxetine Duloxetine The metabolism of Duloxetine can be increased when combined with Streptozocin.
Cinacalcet Cinacalcet The metabolism of Cinacalcet can be increased when combined with Streptozocin.
Natalizumab Injection Natalizumab Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Natalizumab.
Erlotinib Erlotinib The metabolism of Erlotinib can be increased when combined with Streptozocin.
Palifermin Palifermin The therapeutic efficacy of Palifermin can be decreased when used in combination with Streptozocin.
Entecavir Entecavir The metabolism of Entecavir can be increased when combined with Streptozocin.
Peginterferon Alfa-2a Injection Peginterferon Alfa-2a Injection The risk or severity of adverse effects can be increased when Peginterferon alfa-2a is combined with Streptozocin.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The risk or severity of adverse effects can be increased when Peginterferon alfa-2b is combined with Streptozocin.
Ramelteon Ramelteon The metabolism of Ramelteon can be increased when combined with Streptozocin.
Felbamate Felbamate The metabolism of Felbamate can be increased when combined with Streptozocin.
Abatacept Injection Abatacept Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Abatacept.
Rasagiline Rasagiline The metabolism of Rasagiline can be increased when combined with Streptozocin.
Imatinib Imatinib The risk or severity of adverse effects can be increased when Streptozocin is combined with Imatinib.
Bevacizumab Injection Bevacizumab Injection The risk or severity of adverse effects can be increased when Bevacizumab is combined with Streptozocin.
Bortezomib Bortezomib The risk or severity of adverse effects can be increased when Bortezomib is combined with Streptozocin.
Clofarabine Injection Clofarabine Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Clofarabine.
Hepatitis B Vaccine Hepatitis B Vaccine The therapeutic efficacy of Hepatitis B Vaccine (Recombinant) can be decreased when used in combination with Streptozocin.
Influenza Vaccine, Inactivated or Recombinant Influenza Vaccine, Inactivated or Recombinant The therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Streptozocin.
Influenza Vaccine, Live Intranasal Influenza Vaccine, Live Intranasal The risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Streptozocin.
Live Shingles (Zoster) Vaccine (ZVL) Live Shingles (Zoster) Vaccine (ZVL) The risk or severity of infection can be increased when Varicella Zoster Vaccine (Live/attenuated) is combined with Streptozocin.
Oxaliplatin Injection Oxaliplatin Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Oxaliplatin.
Primaquine Primaquine The metabolism of Primaquine can be increased when combined with Streptozocin.
Rituximab Injection Rituximab Injection The risk or severity of adverse effects can be increased when Rituximab is combined with Streptozocin.
Pemetrexed Injection Pemetrexed Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Pemetrexed.
Vorinostat Vorinostat The risk or severity of adverse effects can be increased when Streptozocin is combined with Vorinostat.
Sorafenib Sorafenib The risk or severity of adverse effects can be increased when Sorafenib is combined with Streptozocin.
Sunitinib Sunitinib The risk or severity of adverse effects can be increased when Streptozocin is combined with Sunitinib.
Dasatinib Dasatinib The risk or severity of adverse effects can be increased when Streptozocin is combined with Dasatinib.
Mexiletine Mexiletine The metabolism of Mexiletine can be increased when combined with Streptozocin.
Azacitidine Injection Azacitidine Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Azacitidine.
Temsirolimus Temsirolimus The risk or severity of adverse effects can be increased when Streptozocin is combined with Temsirolimus.
Nelarabine Injection Nelarabine Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Nelarabine.
Lenalidomide Lenalidomide The risk or severity of adverse effects can be increased when Streptozocin is combined with Lenalidomide.
Nilotinib Nilotinib The risk or severity of adverse effects can be increased when Streptozocin is combined with Nilotinib.
Bexarotene Bexarotene The risk or severity of adverse effects can be increased when Bexarotene is combined with Streptozocin.
Budesonide Budesonide The risk or severity of adverse effects can be increased when Streptozocin is combined with Budesonide.
Chloramphenicol Injection Chloramphenicol Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Chloramphenicol.
Decitabine Injection Decitabine Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Decitabine.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Arsenic trioxide.
Mitoxantrone Injection Mitoxantrone Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Mitoxantrone.
Tretinoin Tretinoin The risk or severity of adverse effects can be increased when Streptozocin is combined with Tretinoin.
Bendamustine Injection Bendamustine Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Bendamustine.
Flecainide Flecainide The metabolism of Flecainide can be increased when combined with Streptozocin.
Certolizumab Injection Certolizumab Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Certolizumab pegol.
Ixabepilone Injection Ixabepilone Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Ixabepilone.
Irinotecan Injection Irinotecan Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Irinotecan.
Estramustine Estramustine The risk or severity of adverse effects can be increased when Streptozocin is combined with Estramustine.
Praziquantel Praziquantel The metabolism of Praziquantel can be increased when combined with Streptozocin.
Alemtuzumab Injection (Chronic Lymphocytic Leukemia) Alemtuzumab Injection (Chronic Lymphocytic Leukemia) The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Streptozocin.
Dexrazoxane Injection Dexrazoxane Injection The risk or severity of adverse effects can be increased when Dexrazoxane is combined with Streptozocin.
Eltrombopag Eltrombopag The metabolism of Eltrombopag can be increased when combined with Streptozocin.
Ibritumomab Injection Ibritumomab Injection The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Streptozocin.
Betaxolol Betaxolol The metabolism of Betaxolol can be increased when combined with Streptozocin.
Prasugrel Prasugrel The risk or severity of bleeding can be increased when Prasugrel is combined with Streptozocin.
Everolimus Everolimus The risk or severity of adverse effects can be increased when Streptozocin is combined with Everolimus.
Pralatrexate Injection Pralatrexate Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Pralatrexate.
Topotecan Topotecan The risk or severity of adverse effects can be increased when Streptozocin is combined with Topotecan.
Golimumab Injection Golimumab Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Golimumab.
Pazopanib Pazopanib The risk or severity of adverse effects can be increased when Streptozocin is combined with Pazopanib.
Asenapine Asenapine The metabolism of Asenapine can be increased when combined with Streptozocin.
Albendazole Albendazole The metabolism of Albendazole can be increased when combined with Streptozocin.
Denosumab Injection Denosumab Injection The risk or severity of adverse effects can be increased when Denosumab is combined with Streptozocin.
Dabigatran Dabigatran The risk or severity of bleeding can be increased when Dabigatran is combined with Streptozocin.
Tocilizumab Injection Tocilizumab Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Tocilizumab.
Fingolimod Fingolimod Streptozocin may increase the immunosuppressive activities of Fingolimod.
Eribulin Injection Eribulin Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Eribulin.
Cabazitaxel Injection Cabazitaxel Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Cabazitaxel.
Acetaminophen Injection Acetaminophen Injection Streptozocin may increase the hepatotoxic activities of Acetaminophen.
Denileukin Diftitox Injection Denileukin Diftitox Injection The risk or severity of adverse effects can be increased when Aldesleukin is combined with Streptozocin.
Sipuleucel-T Injection Sipuleucel-T Injection The therapeutic efficacy of Sipuleucel-T can be decreased when used in combination with Streptozocin.
Belimumab Injection Belimumab Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Belimumab.
Busulfan Injection Busulfan Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Busulfan.
Roflumilast Roflumilast Roflumilast may increase the immunosuppressive activities of Streptozocin.
Cyclophosphamide Injection Cyclophosphamide Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Cyclophosphamide.
Rivaroxaban Rivaroxaban The risk or severity of bleeding can be increased when Rivaroxaban is combined with Streptozocin.
Ticagrelor Ticagrelor The risk or severity of bleeding can be increased when Ticagrelor is combined with Streptozocin.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Brentuximab vedotin.
Ruxolitinib Ruxolitinib The risk or severity of adverse effects can be increased when Streptozocin is combined with Ruxolitinib.
Belatacept Injection Belatacept Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Belatacept.
Basiliximab Injection Basiliximab Injection The risk or severity of adverse effects can be increased when Basiliximab is combined with Streptozocin.
Axitinib Axitinib The metabolism of Axitinib can be increased when combined with Streptozocin.
Melphalan Injection Melphalan Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Melphalan.
Eculizumab Injection Eculizumab Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Eculizumab.
Fondaparinux Injection Fondaparinux Injection The risk or severity of bleeding can be increased when Fondaparinux is combined with Streptozocin.
Carfilzomib Injection Carfilzomib Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Carfilzomib.
Iloprost Iloprost The risk or severity of bleeding can be increased when Iloprost is combined with Streptozocin.
Bosutinib Bosutinib The risk or severity of adverse effects can be increased when Streptozocin is combined with Bosutinib.
Corticotropin, Repository Injection Corticotropin, Repository Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Corticotropin.
Teriflunomide Teriflunomide The risk or severity of adverse effects can be increased when Streptozocin is combined with Teriflunomide.
Icosapent Ethyl Icosapent Ethyl The risk or severity of bleeding can be increased when Icosapent ethyl is combined with Streptozocin.
Tofacitinib Tofacitinib Streptozocin may increase the immunosuppressive activities of Tofacitinib.
Dimethyl Fumarate Dimethyl Fumarate The risk or severity of adverse effects can be increased when Streptozocin is combined with Dimethyl fumarate.
Ponatinib Ponatinib The risk or severity of adverse effects can be increased when Streptozocin is combined with Ponatinib.
Pomalidomide Pomalidomide The risk or severity of adverse effects can be increased when Streptozocin is combined with Pomalidomide.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Trastuzumab emtansine.
Apixaban Apixaban The risk or severity of bleeding can be increased when Apixaban is combined with Streptozocin.
Perampanel Perampanel The metabolism of Perampanel can be increased when combined with Streptozocin.
Ibrutinib Ibrutinib The risk or severity of adverse effects can be increased when Streptozocin is combined with Ibrutinib.
Obinutuzumab Injection Obinutuzumab Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Obinutuzumab.
Dapagliflozin Dapagliflozin The metabolism of Dapagliflozin can be increased when combined with Streptozocin.
Apremilast Apremilast The risk or severity of adverse effects can be increased when Streptozocin is combined with Apremilast.
Siltuximab Injection Siltuximab Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Siltuximab.
Vedolizumab Injection Vedolizumab Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Vedolizumab.
Belinostat Injection Belinostat Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Belinostat.
Idelalisib Idelalisib The risk or severity of adverse effects can be increased when Streptozocin is combined with Idelalisib.
Vorapaxar Vorapaxar The risk or severity of bleeding can be increased when Vorapaxar is combined with Streptozocin.
Edoxaban Edoxaban The risk or severity of bleeding can be increased when Edoxaban is combined with Streptozocin.
Peginterferon Beta-1a Injection Peginterferon Beta-1a Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Peginterferon beta-1a.
Olaparib Olaparib The risk or severity of adverse effects can be increased when Streptozocin is combined with Olaparib.
Blinatumomab Injection Blinatumomab Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Blinatumomab.
Tasimelteon Tasimelteon The metabolism of Tasimelteon can be increased when combined with Streptozocin.
Pirfenidone Pirfenidone The risk or severity of adverse effects can be increased when Streptozocin is combined with Pirfenidone.
Secukinumab Injection Secukinumab Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Secukinumab.
Palbociclib Palbociclib The risk or severity of adverse effects can be increased when Streptozocin is combined with Palbociclib.
Panobinostat Panobinostat The risk or severity of adverse effects can be increased when Streptozocin is combined with Panobinostat.
Dinutuximab Injection Dinutuximab Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Dinutuximab.
Haloperidol Injection Haloperidol Injection The metabolism of Haloperidol can be increased when combined with Streptozocin.
Prednisolone Prednisolone The risk or severity of adverse effects can be increased when Streptozocin is combined with Prednisolone.
Mepolizumab Injection Mepolizumab Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Mepolizumab.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be increased when combined with Streptozocin.
Dexamethasone Injection Dexamethasone Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Dexamethasone.
Defibrotide Injection Defibrotide Injection The risk or severity of bleeding can be increased when Defibrotide is combined with Streptozocin.
Ixekizumab Injection Ixekizumab Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Ixekizumab.
Rucaparib Rucaparib The metabolism of Rucaparib can be increased when combined with Streptozocin.
Brodalumab Injection Brodalumab Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Brodalumab.
Doxepin (Insomnia) Doxepin (Insomnia) The metabolism of Doxepin can be increased when combined with Streptozocin.
Deflazacort Deflazacort The risk or severity of adverse effects can be increased when Streptozocin is combined with Deflazacort.
Ocrelizumab Injection Ocrelizumab Injection Ocrelizumab may increase the immunosuppressive activities of Streptozocin.
Sarilumab Injection Sarilumab Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Sarilumab.
Guselkumab Injection Guselkumab Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Guselkumab.
Enasidenib Enasidenib The metabolism of Enasidenib can be increased when combined with Streptozocin.
Betrixaban Betrixaban The risk or severity of bleeding can be increased when Betrixaban is combined with Streptozocin.
Gemtuzumab Ozogamicin Injection Gemtuzumab Ozogamicin Injection The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Streptozocin.
Penicillamine Penicillamine The risk or severity of adverse effects can be increased when Streptozocin is combined with Penicillamine.
Baricitinib Baricitinib The risk or severity of adverse effects can be increased when Streptozocin is combined with Baricitinib.
Lofexidine Lofexidine The metabolism of Lofexidine can be increased when combined with Streptozocin.
Binimetinib Binimetinib The metabolism of Binimetinib can be increased when combined with Streptozocin.
Stiripentol Stiripentol The metabolism of Stiripentol can be increased when combined with Streptozocin.
Methoxy Polyethylene Glycol-Epoetin Beta Injection Methoxy Polyethylene Glycol-Epoetin Beta Injection The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Streptozocin.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Paclitaxel.
Ravulizumab-cwvz Injection Ravulizumab-cwvz Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Ravulizumab.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Emapalumab.
Siponimod Siponimod The risk or severity of adverse effects can be increased when Streptozocin is combined with Siponimod.
Acyclovir Ophthalmic Acyclovir Ophthalmic The metabolism of Acyclovir can be increased when combined with Streptozocin.
Caplacizumab-yhdp Injection Caplacizumab-yhdp Injection The risk or severity of bleeding can be increased when Caplacizumab is combined with Streptozocin.
Risankizumab-rzaa Injection Risankizumab-rzaa Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Risankizumab.
Cladribine Cladribine The risk or severity of adverse effects can be increased when Cladribine is combined with Streptozocin.
Triclabendazole Triclabendazole The metabolism of Triclabendazole can be increased when combined with Streptozocin.
Istradefylline Istradefylline The metabolism of Istradefylline can be increased when combined with Streptozocin.
Phenytoin Injection Phenytoin Injection The metabolism of Phenytoin can be increased when combined with Streptozocin.
Cenobamate Cenobamate The metabolism of Cenobamate can be increased when combined with Streptozocin.
Ozanimod Ozanimod The risk or severity of adverse effects can be increased when Streptozocin is combined with Ozanimod.
Selumetinib Selumetinib The metabolism of Selumetinib can be increased when combined with Streptozocin.
Theophylline Theophylline The metabolism of Theophylline can be increased when combined with Streptozocin.
Indomethacin Indomethacin The risk or severity of adverse effects can be increased when Indomethacin is combined with Streptozocin.
Naproxen Naproxen The metabolism of Naproxen can be increased when combined with Streptozocin.
Hydroxyurea Hydroxyurea The risk or severity of adverse effects can be increased when Streptozocin is combined with Hydroxyurea.
Floxuridine Floxuridine The risk or severity of adverse effects can be increased when Floxuridine is combined with Streptozocin.
Phenobarbital Phenobarbital The metabolism of Phenobarbital can be increased when combined with Streptozocin.
Methotrexate Injection Methotrexate Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Methotrexate.
Primidone Primidone The metabolism of Primidone can be increased when combined with Streptozocin.
Chlorpromazine Chlorpromazine The metabolism of Chlorpromazine can be increased when combined with Streptozocin.
Carmustine Carmustine The risk or severity of adverse effects can be increased when Carmustine is combined with Streptozocin.
Procarbazine Procarbazine The risk or severity of adverse effects can be increased when Streptozocin is combined with Procarbazine.
Thioguanine Thioguanine The risk or severity of adverse effects can be increased when Tioguanine is combined with Streptozocin.
Trifluoperazine Trifluoperazine The metabolism of Trifluoperazine can be increased when combined with Streptozocin.
Bleomycin Bleomycin The risk or severity of adverse effects can be increased when Bleomycin is combined with Streptozocin.
Maprotiline Maprotiline The metabolism of Maprotiline can be increased when combined with Streptozocin.
Perphenazine Perphenazine The metabolism of Perphenazine can be increased when combined with Streptozocin.
Azathioprine Azathioprine The risk or severity of adverse effects can be increased when Streptozocin is combined with Azathioprine.
Sulfasalazine Sulfasalazine The risk or severity of adverse effects can be increased when Streptozocin is combined with Sulfasalazine.
Lomustine Lomustine The risk or severity of adverse effects can be increased when Streptozocin is combined with Lomustine.
Doxorubicin Doxorubicin The risk or severity of adverse effects can be increased when Streptozocin is combined with Doxorubicin.
Cytarabine Cytarabine The risk or severity of adverse effects can be increased when Streptozocin is combined with Cytarabine.
Mechlorethamine Mechlorethamine The risk or severity of adverse effects can be increased when Streptozocin is combined with Mechlorethamine.
Dactinomycin Dactinomycin The risk or severity of adverse effects can be increased when Streptozocin is combined with Dactinomycin.
Carbamazepine Carbamazepine The risk or severity of adverse effects can be increased when Streptozocin is combined with Carbamazepine.
Clonidine Clonidine The metabolism of Clonidine can be increased when combined with Streptozocin.
Warfarin Warfarin The metabolism of Warfarin can be increased when combined with Streptozocin.
Daunorubicin Daunorubicin The risk or severity of adverse effects can be increased when Streptozocin is combined with Daunorubicin.
Quinine Quinine The metabolism of Quinine can be increased when combined with Streptozocin.
Ethosuximide Ethosuximide The metabolism of Ethosuximide can be increased when combined with Streptozocin.
Triamterene Triamterene The metabolism of Triamterene can be increased when combined with Streptozocin.
Sulfinpyrazone Sulfinpyrazone The risk or severity of bleeding can be increased when Sulfinpyrazone is combined with Streptozocin.
Chlorothiazide Chlorothiazide The risk or severity of neutropenia and thrombocytopenia can be increased when Chlorothiazide is combined with Streptozocin.
Amitriptyline Amitriptyline The metabolism of Amitriptyline can be increased when combined with Streptozocin.
Imipramine Imipramine The metabolism of Imipramine can be increased when combined with Streptozocin.
Disopyramide Disopyramide The metabolism of Disopyramide can be increased when combined with Streptozocin.
Tamoxifen Tamoxifen The metabolism of Tamoxifen can be increased when combined with Streptozocin.
Mitomycin Mitomycin The risk or severity of adverse effects can be increased when Mitomycin is combined with Streptozocin.
Methimazole Methimazole The risk or severity of adverse effects can be increased when Streptozocin is combined with Methimazole.
Propylthiouracil Propylthiouracil The risk or severity of adverse effects can be increased when Streptozocin is combined with Propylthiouracil.
Cyclobenzaprine Cyclobenzaprine The metabolism of Cyclobenzaprine can be increased when combined with Streptozocin.
Methyclothiazide Methyclothiazide The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Streptozocin.
Hydrochlorothiazide Hydrochlorothiazide The risk or severity of neutropenia and thrombocytopenia can be increased when Hydrochlorothiazide is combined with Streptozocin.
Chlorzoxazone Chlorzoxazone The metabolism of Chlorzoxazone can be increased when combined with Streptozocin.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The metabolism of Propranolol can be increased when combined with Streptozocin.
Mercaptopurine Mercaptopurine The risk or severity of adverse effects can be increased when Streptozocin is combined with Mercaptopurine.
Allopurinol Allopurinol The risk or severity of adverse effects can be increased when Allopurinol is combined with Streptozocin.
Fluorouracil Injection Fluorouracil Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Fluorouracil.
Colchicine Colchicine The risk or severity of adverse effects can be increased when Streptozocin is combined with Colchicine.
Dacarbazine Dacarbazine The risk or severity of adverse effects can be increased when Streptozocin is combined with Dacarbazine.
Bacillus Calmette-Guerin (BCG) Vaccine Bacillus Calmette-Guerin (BCG) Vaccine The risk or severity of infection can be increased when Bacillus calmette-guerin substrain tice live antigen is combined with Streptozocin.
Thiotepa Injection Thiotepa Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Thiotepa.
Vincristine Injection Vincristine Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Vincristine.
Dipyridamole Dipyridamole The risk or severity of bleeding can be increased when Dipyridamole is combined with Streptozocin.
Vinblastine Vinblastine The risk or severity of adverse effects can be increased when Streptozocin is combined with Vinblastine.
Thiothixene Thiothixene The metabolism of Thiothixene can be increased when combined with Streptozocin.
Aspirin Aspirin The risk or severity of bleeding can be increased when Acetylsalicylic acid is combined with Streptozocin.
Chlorambucil Chlorambucil The risk or severity of adverse effects can be increased when Chlorambucil is combined with Streptozocin.
Nifedipine Nifedipine The metabolism of Nifedipine can be increased when combined with Streptozocin.
Verapamil Verapamil The metabolism of Verapamil can be increased when combined with Streptozocin.
Cisplatin Injection Cisplatin Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Cisplatin.
Etoposide Etoposide The risk or severity of adverse effects can be increased when Streptozocin is combined with Etoposide.
Pentoxifylline Pentoxifylline The metabolism of Pentoxifylline can be increased when combined with Streptozocin.
Guanabenz Guanabenz The metabolism of Guanabenz can be increased when combined with Streptozocin.
Pimozide Pimozide The metabolism of Pimozide can be increased when combined with Streptozocin.
Diclofenac Diclofenac The metabolism of Diclofenac can be increased when combined with Streptozocin.
Fluoxetine Fluoxetine The metabolism of Fluoxetine can be increased when combined with Streptozocin.
Interferon Alfa-2b Injection Interferon Alfa-2b Injection The risk or severity of adverse effects can be increased when Interferon alfa-2b is combined with Streptozocin.
Clozapine Clozapine The risk or severity of neutropenia can be increased when Streptozocin is combined with Clozapine.
Idarubicin Idarubicin The risk or severity of adverse effects can be increased when Streptozocin is combined with Idarubicin.
Fludarabine Injection Fludarabine Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Fludarabine.
Pentostatin Injection Pentostatin Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Pentostatin.
Nabumetone Nabumetone The metabolism of Nabumetone can be increased when combined with Streptozocin.
Epoetin Alfa, Injection Epoetin Alfa, Injection The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Streptozocin.
Teniposide Injection Teniposide Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Teniposide.
Zolpidem Zolpidem The metabolism of Zolpidem can be increased when combined with Streptozocin.
Fluvoxamine Fluvoxamine The metabolism of Fluvoxamine can be increased when combined with Streptozocin.
Vinorelbine Injection Vinorelbine Injection The risk or severity of adverse effects can be increased when Vinorelbine is combined with Streptozocin.
Carboplatin Injection Carboplatin Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Carboplatin.
Ifosfamide Injection Ifosfamide Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Ifosfamide.
Pegaspargase Injection Pegaspargase Injection The risk or severity of adverse effects can be increased when Pegaspargase is combined with Streptozocin.
Ticlopidine Ticlopidine The risk or severity of bleeding can be increased when Ticlopidine is combined with Streptozocin.
Dalteparin Injection Dalteparin Injection The risk or severity of bleeding can be increased when Dalteparin is combined with Streptozocin.
Riluzole Riluzole The metabolism of Riluzole can be increased when combined with Streptozocin.
Gemcitabine Injection Gemcitabine Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Gemcitabine.
Docetaxel Injection Docetaxel Injection The risk or severity of adverse effects can be increased when Streptozocin is combined with Docetaxel.
Clomipramine Clomipramine The metabolism of Clomipramine can be increased when combined with Streptozocin.
Mirtazapine Mirtazapine The metabolism of Mirtazapine can be increased when combined with Streptozocin.
Zileuton Zileuton The metabolism of Zileuton can be increased when combined with Streptozocin.
Carvedilol Carvedilol The metabolism of Carvedilol can be increased when combined with Streptozocin.
Flutamide Flutamide The metabolism of Flutamide can be increased when combined with Streptozocin.
Selegiline Selegiline The metabolism of Selegiline can be increased when combined with Streptozocin.
Propafenone Propafenone The metabolism of Propafenone can be increased when combined with Streptozocin.
Ropinirole Ropinirole The metabolism of Ropinirole can be increased when combined with Streptozocin.
Paroxetine Paroxetine The metabolism of Paroxetine can be increased when combined with Streptozocin.
Capecitabine Capecitabine The risk or severity of adverse effects can be increased when Streptozocin is combined with Capecitabine.
Efavirenz Efavirenz The metabolism of Efavirenz can be increased when combined with Streptozocin.
Trastuzumab Injection Trastuzumab Injection Trastuzumab may increase the neutropenic activities of Streptozocin.
Thalidomide Thalidomide The risk or severity of adverse effects can be increased when Streptozocin is combined with Thalidomide.
Terbinafine Terbinafine The metabolism of Terbinafine can be increased when combined with Streptozocin.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists

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