Inactive ingredients by manufacturer

Tiopronin inactive ingredients by manufacturer

Wondering whether your Tiopronin has lactose, gluten, soy, a dye or gelatin in it? The medicine is the same, but the fillers, coatings and colors differ from one company to the next. This page shows what each Tiopronin product's FDA label lists, so you can find a version that leaves out what you avoid and ask your pharmacist for it by its NDC.

We have read the FDA labels of 13 of the 16 current Tiopronin products on the market today, from 8 companies listing it with the FDA, and lined them up side by side. 3 are still being read and will appear on a later visit.

Ask about your bottle

Is there something in your Tiopronin? Ask in plain words.

Name the company, strength or the NDC on your bottle and the ingredient you avoid. The answer comes only from the FDA labels on this page.

Answers are drawn from the FDA label data on this page and checked against it. They are not medical advice: confirm with your pharmacist before relying on them.

The short answer

Which Tiopronin products list lactose, a gluten source, soy, dyes or gelatin?

  1. LactoseDiffers by manufacturer

    12 of 13 checked products list lactose; 1 does not. See the products

    Does not list it Mission Pharmacal
    Lists it Amneal BioComp Cycle Endo Mission Pharmacal Teva Pharmaceuticals, Inc. Teva Pharmaceuticals USA, Inc. Torrent
  2. Wheat or gluten sourceNo checked product

    No checked Tiopronin product lists a wheat or gluten source.

  3. SoyNo checked product

    No checked Tiopronin product lists soy.

  4. Synthetic dyesDiffers by manufacturer

    3 of 13 checked products list synthetic dyes; 10 do not. See the products

    Does not list it Cycle Endo Mission Pharmacal Teva Pharmaceuticals, Inc. Teva Pharmaceuticals USA, Inc. Torrent
    Lists it Amneal BioComp Mission Pharmacal
  5. GelatinNo checked product

    No checked Tiopronin product lists gelatin.

Also listed by some products: Corn 1 of 13 Titanium dioxide 2 of 13 Carmine or shellac 6 of 13 Alcohol 1 of 13 Propylene glycol 6 of 13 PEG or polysorbate 1 of 13 Sugar 2 of 13

Find a version without it

Every current Tiopronin product and what its label lists

Hide products that list:

ProductListsInactive ingredients on the label
Amneal Pharmaceuticals NY LLC 1 product
300 mg delayed-release tabletNDC 60219-2009-09 Lactose Synthetic dyes Titanium dioxide Carmine or shellac Alcohol (ethanol) Propylene glycol
Show 14 ingredients

ALCOHOL, BUTYL ALCOHOL, FD&C RED NO. 40, HYDROXYPROPYL CELLULOSE, LOW SUBSTITUTED, HYDROXYPROPYL CELLULOSE, UNSPECIFIED, HYPROMELLOSE 2910 (5 MPA.S), LACTOSE MONOHYDRATE, MAGNESIUM STEARATE, METHACRYLIC ACID AND ETHYL ACRYLATE COPOLYMER, PROPYLENE GLYCOL, SHELLAC, TALC, TITANIUM DIOXIDE, TRIETHYL CITRATE
BioComp Pharma, Inc. 3 products
100 mg delayed-release tabletNDC 44523-0054-01 Still being read Not read yet
300 mg delayed-release tabletNDC 44523-0055-01 Still being read Not read yet
100 mg tabletNDC 44523-0053-01 Lactose Synthetic dyes Titanium dioxide Sugar (sucrose, dextrose)
Show 13 ingredients

ALUMINUM OXIDE, CALCIUM CARBONATE, CARNAUBA WAX, DIMETHYLAMINOETHYL METHACRYLATE - BUTYL METHACRYLATE - METHYL METHACRYLATE COPOLYMER, ETHYLCELLULOSES, FD&C RED NO. 40, HYDROXYPROPYL CELLULOSE (70000 WAMW), LACTOSE, MAGNESIUM SILICATE, MAGNESIUM STEARATE, POVIDONE, UNSPECIFIED, SUCROSE, TITANIUM DIOXIDE
Cycle Pharmaceuticals Ltd. 2 products
100 mg delayed-release tabletNDC 70709-0121-30 Lactose
Show 8 ingredients

HYDROXYPROPYL CELLULOSE, LOW SUBSTITUTED, HYDROXYPROPYL CELLULOSE, UNSPECIFIED, HYPROMELLOSE, UNSPECIFIED, LACTOSE MONOHYDRATE, MAGNESIUM STEARATE, METHACRYLIC ACID - ETHYL ACRYLATE COPOLYMER (1:1) TYPE A, TALC, TRIETHYL CITRATE
300 mg delayed-release tabletNDC 70709-0123-90 Lactose
Show 8 ingredients

HYDROXYPROPYL CELLULOSE, LOW SUBSTITUTED, HYDROXYPROPYL CELLULOSE, UNSPECIFIED, HYPROMELLOSE, UNSPECIFIED, LACTOSE MONOHYDRATE, MAGNESIUM STEARATE, METHACRYLIC ACID - ETHYL ACRYLATE COPOLYMER (1:1) TYPE A, TALC, TRIETHYL CITRATE
Endo USA, Inc. 2 products
100 mg delayed-release tabletNDC 00254-3034-30 Lactose Carmine or shellac Propylene glycol
Show 14 ingredients

AMMONIA, ANHYDROUS LACTOSE, DIMETHICONE, FERRIC OXIDE RED, HYDROXYPROPYL CELLULOSE, UNSPECIFIED, HYPROMELLOSE, UNSPECIFIED, LOW-SUBSTITUTED HYDROXYPROPYL CELLULOSE (11% HYDROXYPROPYL; 130000 MW), MAGNESIUM STEARATE, METHACRYLIC ACID AND ETHYL ACRYLATE COPOLYMER, PROPYLENE GLYCOL, SHELLAC, SILICON DIOXIDE, TALC, TRIETHYL CITRATE
300 mg delayed-release tabletNDC 00254-3035-09 Lactose Carmine or shellac Propylene glycol
Show 14 ingredients

AMMONIA, ANHYDROUS LACTOSE, DIMETHICONE, FERRIC OXIDE RED, HYDROXYPROPYL CELLULOSE, UNSPECIFIED, HYPROMELLOSE, UNSPECIFIED, LOW-SUBSTITUTED HYDROXYPROPYL CELLULOSE (11% HYDROXYPROPYL; 130000 MW), MAGNESIUM STEARATE, METHACRYLIC ACID AND ETHYL ACRYLATE COPOLYMER, PROPYLENE GLYCOL, SHELLAC, SILICON DIOXIDE, TALC, TRIETHYL CITRATE
Mission Pharmacal Company 3 products
100 mg delayed-release tabletNDC 00178-0902-01 Still being read Not read yet
300 mg delayed-release tabletNDC 00178-0901-90 Lactose
Show 8 ingredients

HYDROXYPROPYL CELLULOSE, LOW SUBSTITUTED, HYDROXYPROPYL CELLULOSE, UNSPECIFIED, HYPROMELLOSE, UNSPECIFIED, LACTOSE MONOHYDRATE, MAGNESIUM STEARATE, METHACRYLIC ACID - ETHYL ACRYLATE COPOLYMER (1:1) TYPE A, TALC, TRIETHYL CITRATE
100 mg tabletNDC 00178-0900-01 Synthetic dyes
Show 4 ingredients

ALUMINUM OXIDE, FD&C RED NO. 40, HYDROXYPROPYL CELLULOSE (70000 WAMW), POVIDONE, UNSPECIFIED
Teva Pharmaceuticals, Inc. 2 products
100 mg delayed-release tabletNDC 00480-9227-55 Lactose Carmine or shellac Propylene glycol
Show 13 ingredients

AMMONIA, FERROSOFERRIC OXIDE, HYDROXYPROPYL CELLULOSE, UNSPECIFIED, HYPROMELLOSE 2910 (6 MPA.S), LACTOSE MONOHYDRATE, LOW-SUBSTITUTED HYDROXYPROPYL CELLULOSE (11% HYDROXYPROPYL; 130000 MW), MAGNESIUM STEARATE, METHACRYLIC ACID AND ETHYL ACRYLATE COPOLYMER, PROPYLENE GLYCOL, SHELLAC, SILICON DIOXIDE, TALC, TRIETHYL CITRATE
300 mg delayed-release tabletNDC 00480-7824-98 Lactose Carmine or shellac Propylene glycol
Show 13 ingredients

AMMONIA, FERROSOFERRIC OXIDE, HYDROXYPROPYL CELLULOSE, UNSPECIFIED, HYPROMELLOSE 2910 (6 MPA.S), LACTOSE MONOHYDRATE, LOW-SUBSTITUTED HYDROXYPROPYL CELLULOSE (11% HYDROXYPROPYL; 130000 MW), MAGNESIUM STEARATE, METHACRYLIC ACID AND ETHYL ACRYLATE COPOLYMER, PROPYLENE GLYCOL, SHELLAC, SILICON DIOXIDE, TALC, TRIETHYL CITRATE
Teva Pharmaceuticals USA, Inc. 1 product
100 mg tabletNDC 00093-7909-00 Lactose Corn-derived Carmine or shellac Propylene glycol Polyethylene glycol or polysorbate Sugar (sucrose, dextrose)
Show 22 ingredients

AMMONIA, ETHYLCELLULOSE (7 MPA.S), FERROSOFERRIC OXIDE, GLYCERYL MONOCAPRYLOCAPRATE, GLYCERYL MONOSTEARATE, HYDROXYPROPYL CELLULOSE (90000 WAMW), HYPROMELLOSE 2910 (5 MPA.S), LACTOSE MONOHYDRATE, LOW-SUBSTITUTED HYDROXYPROPYL CELLULOSE (11% HYDROXYPROPYL; 130000 MW), MAGNESIUM STEARATE, MEDIUM-CHAIN TRIGLYCERIDES, MICROCRYSTALLINE CELLULOSE, POLYETHYLENE GLYCOL 3350, POLYVINYL ALCOHOL, UNSPECIFIED, PROPYLENE GLYCOL, SHELLAC, SILICON DIOXIDE, SODIUM LAURYL SULFATE, STARCH, CORN, STEARIC ACID, SUCROSE, TALC
Torrent Pharmaceuticals Limited 2 products
100 mg delayed-release tabletNDC 13668-0691-03 Lactose
Show 8 ingredients

HYDROXYPROPYL CELLULOSE, LOW SUBSTITUTED, HYDROXYPROPYL CELLULOSE, UNSPECIFIED, HYPROMELLOSE, UNSPECIFIED, LACTOSE MONOHYDRATE, MAGNESIUM STEARATE, METHACRYLIC ACID - ETHYL ACRYLATE COPOLYMER (1:1) TYPE A, TALC, TRIETHYL CITRATE
300 mg delayed-release tabletNDC 13668-0692-90 Lactose
Show 8 ingredients

HYDROXYPROPYL CELLULOSE, LOW SUBSTITUTED, HYDROXYPROPYL CELLULOSE, UNSPECIFIED, HYPROMELLOSE, UNSPECIFIED, LACTOSE MONOHYDRATE, MAGNESIUM STEARATE, METHACRYLIC ACID - ETHYL ACRYLATE COPOLYMER (1:1) TYPE A, TALC, TRIETHYL CITRATE

A product with none of these listed is not certified to be without them: the label says what the manufacturer declared, and the source of a starch or a flavor is often not stated. The companies are the FDA's labelers, which include repackagers and distributors selling another company's product under their own label. The NDC opens the product's own page, with the full label and its inactive-ingredient notes.

Tiopronin without lactose

Lactose: milk sugar; a concern with lactose intolerance or a milk allergy. 12 of 13 checked products list lactose; 1 does not.

Does not list lactose

Lists lactose

Tiopronin without synthetic dyes

Synthetic dyes: FD&C or D&C colorants and their aluminum lakes. 3 of 13 checked products list synthetic dyes; 10 do not.

Does not list synthetic dyes

Lists synthetic dyes

Tiopronin without corn-derived ingredients

Corn-derived: corn starch, maize or corn syrup; a concern with corn allergy. 1 of 13 checked products list corn-derived ingredients; 12 do not.

Does not list corn-derived ingredients

Lists corn-derived ingredients

Tiopronin without titanium dioxide

Titanium dioxide: A white colorant some people choose to avoid. 2 of 13 checked products list titanium dioxide; 11 do not.

Does not list titanium dioxide

Lists titanium dioxide

Tiopronin without carmine or shellac

Carmine or shellac: insect-derived red colorant or coating glaze. 6 of 13 checked products list carmine or shellac; 7 do not.

Does not list carmine or shellac

Lists carmine or shellac

Tiopronin without alcohol (ethanol)

Alcohol (ethanol): mostly in liquids; a concern in alcohol recovery, for children, or with disulfiram or metronidazole. 1 of 13 checked products list alcohol (ethanol); 12 do not.

Does not list alcohol (ethanol)

Lists alcohol (ethanol)

Tiopronin without propylene glycol

Propylene glycol: A solvent in liquids and capsules; a concern in kidney disease, for infants, and at high doses. 6 of 13 checked products list propylene glycol; 7 do not.

Does not list propylene glycol

Lists propylene glycol

Tiopronin without polyethylene glycol or polysorbate

Polyethylene glycol or polysorbate: PEG, macrogol or polysorbate; a rare cause of allergic reactions. 1 of 13 checked products list polyethylene glycol or polysorbate; 12 do not.

Does not list polyethylene glycol or polysorbate

Lists polyethylene glycol or polysorbate

Tiopronin without sugar (sucrose or dextrose)

Sugar (sucrose, dextrose): A consideration in diabetes, mostly in liquids and chewables. 2 of 13 checked products list sugar (sucrose or dextrose); 11 do not.

Does not list sugar (sucrose or dextrose)

Lists sugar (sucrose or dextrose)

At the pharmacy counter

How to use this at the pharmacy counter

  1. Pick the company whose list suits you and copy the NDC from the table. Many pharmacies order from wholesalers that carry several companies' versions and can request a particular one if you ask before the prescription is filled; some buy from one contracted source only, and a few insurance plans cover only certain NDCs, so ask the pharmacist to check.
  2. Treat "does not list" as exactly that. The label is what the manufacturer declared; a flavor or a starch may have an unstated source, and lines change. For celiac disease or a serious allergy, ask the manufacturer's medical information line for a written statement about the lot you have.
  3. Check the bottle each refill. A different company usually means a different shape, color and inactive-ingredient list; the pharmacist can tell you who made it, and the two-NDC comparison shows the difference line by line.
  4. If you need one company's version kept constant, ask your prescriber to write that company or the NDC on the prescription and tell the pharmacy you need it held. Rules vary by state and plan, so confirm with the pharmacist.
Ask Dr. Staiger which Tiopronin product suits you →

Common questions about Tiopronin inactive ingredients

Is Tiopronin gluten-free?
This page cannot certify any Tiopronin product gluten-free; it reports what each label declares. Of the 13 products checked, none lists a wheat, barley, rye or gluten ingredient, and none lists a starch without a stated source. If you have celiac disease, ask the manufacturer's medical information line for a written gluten statement for the lot you have.
Does Tiopronin contain lactose?
12 of 13 checked Tiopronin products list lactose; 1 does not: Mission Pharmacal (100 mg tablet). The lactose in a tablet or capsule is a small amount, but people with a milk allergy or a strong intolerance often prefer a version that does not list it.
Does Tiopronin contain soy?
No checked Tiopronin product lists a soy ingredient (soybean oil or soy lecithin) on its label. Soy lecithin is the usual form and the amount is small, but people with a soy allergy often prefer a version that does not list it.
Is there a dye-free Tiopronin?
3 of 13 checked Tiopronin products list a synthetic dye (an FD&C or D&C colorant); 10 do not: Cycle (100 mg delayed-release tablet and 300 mg delayed-release tablet), Endo (100 mg delayed-release tablet and 300 mg delayed-release tablet), Mission Pharmacal (300 mg delayed-release tablet) and Teva Pharmaceuticals, Inc. (100 mg delayed-release tablet and 300 mg delayed-release tablet) and 2 other companies. Colorants often differ by strength within one company's line, so compare the lists above strength by strength.
Does Tiopronin contain gelatin?
No checked Tiopronin product lists gelatin on its label. Gelatin is usually bovine or porcine and the label rarely says which; for kosher, halal or vegetarian needs, ask the manufacturer.
Why do the inactive ingredients differ between manufacturers?
A generic must match the brand's active ingredient, strength, dose form and how it is absorbed; its fillers, binders, coatings and colorants are the manufacturer's own choice. That is why one Tiopronin product can list lactose and a dye while another from a different company lists neither.
Can my pharmacy give me a specific manufacturer's version?
Often, if you ask before the prescription is filled: many pharmacies order from wholesalers that carry several companies' versions and can request a particular one. Some pharmacies buy a generic from one contracted source only, and a few insurance plans cover only certain NDCs, so ask the pharmacist to check. Give them the NDC from this page; the company name alone is often enough.
How current is this list?
The products are the ones in the FDA's current NDC directory as of October 6, 2026, and each inactive-ingredient list is the manufacturer's FDA label as our label sync last read it. Formulations change, so check the label on your own bottle and ask your pharmacist if a refill looks different.

Sources: the products are the finished Tiopronin products in the FDA's current NDC directory (openFDA), as of October 6, 2026; each inactive-ingredient list is the manufacturer's FDA Structured Product Label via DailyMed, as our label sync last read it. The concern groups are HelloPharmacist's classification of the names the label declares. Educational information only, not medical advice; confirm with your pharmacist before relying on a list. ← Back to the Tiopronin guide