Advil Allergy and Congestion Relief chlorpheniramine maleate, ibuprofen, and phenylephrine hydrochloride 4 mg; 200 mg; 10 mg Tablet, Coated — NDC 0573-2161-03 (Billing 00573-2161-03)
This is a package of Advil Allergy and Congestion Relief chlorpheniramine maleate, ibuprofen, and phenylephrine hydrochloride 4 mg; 200 mg; 10 mg Tablet, Coated from Haleon US Holdings LLC, marketed since Jul 2012 and currently FDA-listed. It is this product's only package size.
NDC database record
One package, one record: these facts belong to NDC 0573-2161-03 alone.
- Record
- FDA NDC Directory package listing · Human OTC drug
- Code segments
- 0573 labeler · 2161 product · 03 package
- Package marketed since
- Oct 1, 2019
- Sample package
- No — commercial package
- Listing certified through
- Dec 31, 2026
- Barcode (UPC-A, from the NDC)
- 3 0573216103 7
- FDA record last changed
- Oct 1, 2026
Identity & classification
Regulatory identifiers FDA, NLM and CMS codes for this package
- RxCUI (RxNorm): 1310503
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 1, 2026
- FDA label on DailyMed · label index refreshed Oct 3, 2026
- RxNorm (NLM RxNav) · catalog refreshed Oct 1, 2026
- Medi-Span GPI (licensed)
- First Databank (licensed) · refreshed Oct 1, 2026
RxNorm drug class
This medicine belongs to the Histamine-1 Receptor Antagonist class.
Where does this data come from?
- RxClass (NLM) · catalog refreshed Oct 1, 2026
Clinical
Chlorpheniramine is used to treat allergy symptoms: sneezing runny nose itchy nose or throat red, itchy, watery eyes Chlorpheniramine is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms.
Read the full MedlinePlus article ↗- It temporarily relieves cold, flu or allergy symptoms. That includes stuffy or runny nose, sneezing, sinus pressure, headache, body aches and fever. The Allergy products also help...
- If you are 12 or older, the label says 1 tablet about every 4 hours while symptoms last. Do not go over 6 tablets in 24 hours unless a doctor tells you to. It is not for children u...
- It can. Be careful driving or using machinery until you know how it affects you. Alcohol, sedatives and tranquilizers can make drowsiness worse, so avoid alcohol. Some people, espe...
- It can, because it contains an NSAID. Taking it with food or milk may help. If you feel faint, vomit blood, or have black or bloody stools or stomach pain that does not go away, st...
Patient education
Supplement & herbal interactions
Where does this data come from?
- MedlinePlus (NLM) · refreshed Oct 1, 2026
- FDA label on DailyMed · label index refreshed Oct 3, 2026
Ask a licensed pharmacist directly — free, answered by our team.
Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per each | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | Not in the retail survey — common for institutional, discontinued, or low-volume packs. | |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
Where does this data come from?
- CMS NADAC weekly file
- CMS ASP pricing files · refreshed Sep 20, 2026
- CMS Medicaid State Drug Utilization Data · refreshed Oct 4, 2026
- CMS Part D plan pricing files · refreshed Sep 24, 2026
- VA National Acquisition Center price file
Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Marketing end | Status |
|---|---|---|---|---|
| 00573-2161-03 You're viewing this Main listing | 2 BLISTER PACK in 1 CARTON / 10 TABLET, COATED in 1 BLISTER PACK | 2019-10-01 | — | Active |
Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Advil Multi-Symptom Cold and Flu 4 mg/1; 200 mg/1; 10 mg 00573-0190-01 | Haleon | 1 tablet | — | — | FDA listed | — |
| Advil Allergy and Congestion Relief 4 mg/1; 200 mg/1; 10 mg 00573-0196-01 | Haleon | 1 tablet | — | — | FDA listed | — |
| Advil Allergy and Congestion Relief 4 mg/1; 200 mg/1; 10 mgthis 00573-2161-03 | Haleon | 10 tablets | — | — | FDA listed | — |
| Advil Allergy and Congestion Relief 4 mg/1; 200 mg/1; 10 mg 67751-0149-01 | Navajo | 1 tablet | — | — | FDA listed | — |
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 1, 2026
- FDA Orange Book · refreshed Oct 3, 2026
- CMS NADAC weekly file
Availability & generic status
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
- FDA Orange Book · refreshed Oct 3, 2026
What it looks like
Where does this data come from?
- FDA label on DailyMed · label index refreshed Oct 3, 2026
Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
-
UNII 23OV73Q5G9
Acesulfame potassium is an artificial sweetener that tastes about 200 times sweeter than sugar. It's added to medicines to improve taste without adding calories or affecting blood sugar.
-
UNII R12CBM0EIZ
A natural wax derived from a Brazilian palm tree, used as a coating and polish on tablets and capsules. It creates a smooth, shiny finish that protects the medicine and improves appearance.
-
UNII M28OL1HH48
Croscarmellose sodium is a plant-based substance derived from cellulose. It acts as a disintegrant, helping tablets and capsules break down quickly in the digestive system so the medicine can be absorbed.
-
UNII 1Z74184RGV
Egg phospholipids are naturally derived fats from eggs that help mix oil and water-based ingredients together. They work as emulsifiers in medicines, keeping the formula stable and uniform.
-
UNII 1K09F3G675
Ferric oxide red is an inorganic iron compound used as a colorant in medicines. It gives tablets, capsules, or other dosage forms a red or reddish tint for identification and appearance.
-
UNII PDC6A3C0OX
Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
-
UNII R8WTH25YS2
Glyceryl dibehenate is a wax-like substance made from behenate fatty acids and glycerol. It functions as a binder and release-control agent in tablets and capsules, helping hold ingredients together and regulate how quickly the medicine dissolves and releases in your body.
-
UNII 3NXW29V3WO
Hypromellose is a plant-based thickener made from cellulose. It's used in medicines as a binder to hold ingredients together, a coating for tablets, and a thickener for liquids.
-
UNII 33X04XA5AT
Lactic acid is a naturally occurring organic acid derived from milk or plant sources. It lowers and maintains pH in formulations, helps preserve the product, and can enhance ingredient stability and absorption.
-
UNII 7CVR7L4A2D
A starch-derived carbohydrate produced by breaking down corn, potato, or tapioca starch. It functions as a filler and binder to give the medicine bulk and texture, and sometimes as a mild sweetener or texture enhancer in powders and tablets.
-
UNII C9H2L21V7U
A fat derived from coconut or palm oil containing shorter fatty acid chains. It serves as a solvent and carrier to help dissolve or suspend active ingredients, improving absorption and stability in liquid formulations.
-
UNII OP1R32D61U
Microcrystalline cellulose is a purified form of cellulose, a natural fiber from plant sources. It acts as a binder and filler in tablets and capsules, helping hold ingredients together and give the medicine its shape and size.
-
UNII VH2XOU12IE
Polydextrose is a synthetic polymer made from dextrose (sugar) that acts as a bulking agent and filler in medicines. It helps give tablets and capsules proper volume and texture while often adding slight sweetness.
-
UNII 532B59J990
Polyvinyl alcohol is a synthetic polymer made from plant-derived materials. It's used as a binder to hold ingredients together, a film-former in coatings, and a thickener in liquid formulations.
-
UNII 8D4SNN7V92
Propyl gallate is a synthetic antioxidant derived from gallic acid. It prevents oils and fats in the medicine from oxidizing and spoiling, helping the product stay stable and effective during storage.
-
UNII ETJ7Z6XBU4
Silicon dioxide is a naturally occurring mineral used as a glidant and anti-caking agent. It helps powder ingredients flow smoothly and prevents clumping during manufacturing and storage.
-
UNII O8232NY3SJ
A plant-based carbohydrate derived from corn kernels. It acts as a filler to add bulk, a binder to hold ingredients together, and a disintegrant to help the tablet break apart in your stomach for absorption.
-
UNII 96K6UQ3ZD4
Sucralose is a synthetic sweetener made from sugar. It's added to medicines to improve taste without adding calories, helping make bitter or unpleasant-tasting drugs easier to take.
-
UNII 7SEV7J4R1U
A powder made from a naturally occurring mineral. In medicines, talc works as a glidant and anti-caking agent, helping tablets and capsules flow smoothly during manufacturing and preventing clumping.
-
UNII 15FIX9V2JP
Titanium dioxide is a bright white mineral powder commonly used as a colorant and opacifying agent. It makes pills and tablets white or lighter in color and helps make coatings non-transparent.
-
UNII XHX3C3X673
Triacetin is a clear, oily liquid made from glycerin and acetic acid. It works as a plasticizer and solvent in medicines, helping soften coatings and improve how liquids mix together in formulations.
-
UNII TTV12P4NEE
Xanthan gum is a thickening and stabilizing ingredient made from fermented corn or other sugars. It's added to medicines to improve texture, prevent separation of liquids and solids, and help the product stay consistent.
22 inactive ingredients listed in the exact product block matched to this NDC.
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.- FDA label on DailyMed · label index refreshed Oct 3, 2026
- FDA openFDA NDC Directory · synced Oct 1, 2026
Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
Why might an inactive ingredient be missing?
Can inactive ingredients matter?
Manufacturer & labeler
More NDCs from Haleon US Holdings LLC labeler code 00573
- Chapstick Moisturizer Cool Mint avobenzone, homosalate, octisalate, octocrylene, white petrolatum 30 mg/g; 40 mg/g; 45 mg/g; 26 mg/g; 369 mg/g Stick NDC 0573-1957-01
- Chapstick Moisturizer Original avobenzone, homosalate, octisalate, octocrylene, white petrolatum 30 mg/g; 40 mg/g; 45 mg/g; 26 mg/g; 384 mg/g Stick NDC 0573-1958-01
- Chapstick Moisturizer Variety Pack avobenzone, homosalate, octisalate, octocrylene, white petrolatum Kit NDC 0573-1959-01
- Chapstick avobenzone, octinoxate, and white petrolatum Kit NDC 0573-2027-01
- Chapstick Classic Medicated camphor, menthol, petrolatum 16 mg/g; 6 mg/g; 410 mg/g Stick NDC 0573-2031-01
- Advil Cold and Sinus ibuprofen and pseudoephedrine hydrochloride 200 mg; 30 mg Tablet, Coated NDC 0573-2160-74
- Nexium 24HR esomeprazole magnesium 20 mg Capsule, Delayed Release NDC 0573-2450-02
- Nexium 24HR esomeprazole magnesium 20 mg Tablet NDC 0573-2451-14
- Nexium 24HR ClearMinis esomeprazole magnesium 20 mg Capsule, Delayed Release NDC 0573-2452-02
- esomeprazole magnesium 20 mg Tablet NDC 0573-2453-00
- Preparation H Hydrocortisone 10 mg/g Cream NDC 0573-2830-10
- Preparation H Cooling Gel phenylephrine hcl, witch hazel 2.5 mg/g; 500 mg/g Gel NDC 0573-2840-10
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 1, 2026
- Drugs@FDA
FDA label — Drug Facts FDA SPL
🎯 Indications and Usage ▾
Uses • temporarily relieves these symptoms associated with hay fever or other upper respiratory allergies, and the common cold: • runny nose • itchy, watery eyes • itching of the nose or throat • sneezing • nasal congestion • sinus pressure • headache • minor body aches and pains • fever • reduces swelling of the nasal passages • temporarily restores freer breathing through the nose
⏱️ Dosage and Administration ▾
Directions • do not take more than directed • adults and children 12 years of age and over: • take 1 tablet every 4 hours while symptoms persist • do not take more than 6 tablets in any 24-hour period, unless directed by a doctor • children under 12 years of age: do not use because this product contains too much medication for children under this age
⚠️ Warnings ▾
Warnings Allergy alert: Ibuprofen may cause a severe allergic reaction, especially in people allergic to aspirin. Symptoms may include: • hives • facial swelling • asthma (wheezing) • shock • skin reddening • rash • blisters If an allergic reaction occurs, stop use and seek medical help right away. Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding.
The chance is higher if you: • are age 60 or older • have had stomach ulcers or bleeding problems • take a blood thinning (anticoagulant) or steroid drug • take other drugs containing prescription or nonprescription NSAIDs [aspirin, ibuprofen, naproxen, or others] • have 3 or more alcoholic drinks every day while using this product • take more or for a longer time than directed Heart attack and stroke warning: NSAIDs, except aspirin, increase the risk of heart attack, heart failure, and stroke. These can be fatal. The risk is higher if you use more than directed or for longer than directed.
Do not use • in children under 12 years of age because this product contains too much medication for children under this age • if you have ever had an allergic reaction to any other pain reliever/fever reducer • right before or after heart surgery • if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Ask a doctor before use if • you have a breathing problem such as emphysema or chronic bronchitis • stomach bleeding warning applies to you • you have problems or serious side effects from taking pain relievers or fever reducers • you have a history of stomach problems, such as heartburn • you have high blood pressure, heart disease, liver cirrhosis, kidney disease, asthma, thyroid disease, diabetes, glaucoma, have trouble urinating due to an enlarged prostate gland, or had a stroke. • you are taking a diuretic Ask a doctor or pharmacist before use if you are • under a doctor's care for any serious condition • taking sedatives or tranquilizers • taking any other product that contains phenylephrine, chlorpheniramine or any other nasal decongestant or antihistamine • taking aspirin for heart attack or stroke, because ibuprofen may decrease this benefit of aspirin • taking any other drug When using this product • take with food or milk if stomach upset occurs • avoid alcoholic drinks • be careful when driving a motor vehicle or operating machinery • drowsiness may occur • alcohol, sedatives, and tranquilizers may increase drowsiness • may cause excitability especially in children Stop use and ask a doctor if • you experience any of the following signs of stomach bleeding: • feel faint • vomit blood • have bloody or black stools • have stomach pain that does not get better • you have symptoms of heart problems or stroke: • chest pain • trouble breathing • weakness in one part or side of body • slurred speech • leg swelling • pain gets worse or lasts more than 7 days • fever gets worse or lasts more than 3 days • nasal congestion lasts for more than 7 days • redness or swelling is present in the painful area • you get nervous, dizzy, or sleepless • symptoms continue or get worse • any new symptoms appear If pregnant or breast-feeding, ask a health professional before use.
It is especially important not to use ibuprofen at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
📦 Storage and Handling ▾
Other information • read all warnings and directions before use. Keep carton. • store at 20-25°C (68-77°F) • avoid excessive heat above 40°C (104°F)
🧪 Active Ingredient ▾
Active ingredients (in each tablet) Chlorpheniramine maleate 4 mg Ibuprofen 200 mg (NSAID)* Phenylephrine HCl 10 mg * nonsteroidal anti-inflammatory drug
🧪 Inactive Ingredients ▾
Inactive ingredients acesulfame potassium, artificial flavors, carnauba wax, colloidal silicon dioxide, corn starch, croscarmellose sodium, glycerin, glyceryl dibehenate, hypromellose, lactic acid, lecithin, maltodextrin, medium-chain triglycerides, microcrystalline cellulose, pharmaceutical ink, polydextrose, polyvinyl alcohol, pregelatinized starch, propyl gallate, silicon dioxide, sucralose, synthetic iron oxide, talc, titanium dioxide, triacetin, xanthan gum
🎯 Purpose ▾
Purposes Antihistamine Pain reliever/Fever reducer Nasal decongestant
📄 Do Not Use ▾
Do not use • in children under 12 years of age because this product contains too much medication for children under this age • if you have ever had an allergic reaction to any other pain reliever/fever reducer • right before or after heart surgery • if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
📄 Ask a Doctor Before Use If ▾
Ask a doctor before use if • you have a breathing problem such as emphysema or chronic bronchitis • stomach bleeding warning applies to you • you have problems or serious side effects from taking pain relievers or fever reducers • you have a history of stomach problems, such as heartburn • you have high blood pressure, heart disease, liver cirrhosis, kidney disease, asthma, thyroid disease, diabetes, glaucoma, have trouble urinating due to an enlarged prostate gland, or had a stroke. • you are taking a diuretic
📄 Ask a Doctor or Pharmacist Before Use If ▾
Ask a doctor or pharmacist before use if you are • under a doctor's care for any serious condition • taking sedatives or tranquilizers • taking any other product that contains phenylephrine, chlorpheniramine or any other nasal decongestant or antihistamine • taking aspirin for heart attack or stroke, because ibuprofen may decrease this benefit of aspirin • taking any other drug
📄 When Using This Product ▾
When using this product • take with food or milk if stomach upset occurs • avoid alcoholic drinks • be careful when driving a motor vehicle or operating machinery • drowsiness may occur • alcohol, sedatives, and tranquilizers may increase drowsiness • may cause excitability especially in children
📄 Stop Use and Ask a Doctor If ▾
Stop use and ask a doctor if • you experience any of the following signs of stomach bleeding: • feel faint • vomit blood • have bloody or black stools • have stomach pain that does not get better • you have symptoms of heart problems or stroke: • chest pain • trouble breathing • weakness in one part or side of body • slurred speech • leg swelling • pain gets worse or lasts more than 7 days • fever gets worse or lasts more than 3 days • nasal congestion lasts for more than 7 days • redness or swelling is present in the painful area • you get nervous, dizzy, or sleepless • symptoms continue or get worse • any new symptoms appear
🤰 If Pregnant or Breast-Feeding ▾
If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use ibuprofen at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.
📄 Keep Out of Reach of Children ▾
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
📄 Questions or Comments ▾
Questions or comments? Call weekdays from 9 AM to 5 PM EST toll free at 1-800-88-ADVIL
📄 Package Label / Principal Display Panel ▾
PRINCIPAL DISPLAY PANEL Advil ALLERGY & CONGESTION RELIEF Chlorpheniramine Maleate 4 mg Antihistamine Ibuprofen 200 mg Pain Reliever/Fever Reducer (NSAID) Phenylephrine HCl 10 mg Nasal Decongestant • Sneezing • Nasal Congestion • Sinus Pressure • Nasal Swelling • Runny Nose • Headache • Fever • Body Aches Advil A&CR ONE PILL DOSE! 10 Coated Tablets PAA147206 Carton Front Advil Allergy & Congestion Relief 10 Coated Tablets
PRINCIPAL DISPLAY PANEL Advil ALLERGY & CONGESTION RELIEF Chlorpheniramine Maleate 4 mg Antihistamine Ibuprofen 200 mg Pain Reliever/Fever Reducer (NSAID) Phenylephrine HCl 10 mg Nasal Decongestant 50% MORE 10 FREE Tablets • Sneezing • Nasal Congestion • Sinus Pressure • Nasal Swelling • Runny Nose • Headache • Fever • Body Aches • Advil Advil A&CR ONE TABLET DOSE! 30 Coated Tablets 000066065 Carton Front Advil Allergy & Congestion Relief 30 ct
About this NDC listing & data coverage
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | ✓ Available |
| Inactive ingredients (structured) | ✓ Available |
| NADAC pharmacy acquisition price (CMS) | — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey. |
| Orange Book / therapeutic-equivalence data | — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope. |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |