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GUNA-DIUR amiloride - apis mellifera - berberis vulgaris fruit - hieracium pilosella flowering top - hydrochlorothiazide - solidago virgaurea flowering top - spironolactone - sus scrofa pituitary gland 4 [hp_X]/30mL; 2 [hp_X]/30mL; .3 g/30mL; 4 [hp_X]/30mL; 12 [hp_X]/30mL; .3 g/30mL; .3 g/30mL Solution/ Drops

by Guna spa · 1 BOTTLE, DROPPER in 1 BOX (17089-260-18) / 30 mL in 1 BOTTLE, DROPPER
NDC 17089-0260-18
🏷️ FDA NDC (as labeled) 17089-260-18 billing pads the product segment with a zero
Rx only On market Non-controlled
🗂️ Data synced Sep 17, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 17089-260-18
Product NDC 17089-260
11-digit billing NDC 17089026018
UNII 7DZO8EB0Z3, 7S82P3R43Z, 6XEF22AHC3, 0J48LPH2TH, L0PFEMQ1DT, 08A7Y81S1P +2 more
SPL Set ID 3f91cd92-eb6d-4bda-9cad-2e11e0b0fbe2
Established class (EPC) Potassium-sparing Diuretic; Standardized Insect Venom Allergenic Extract; Thiazide Diuretic; Aldosterone Antagonist
Mechanism of action Aldosterone Antagonists
Physiologic effect Decreased Renal K+ Excretion; Increased Diuresis; Increased Histamine Release; Cell-mediated Immunity; Increased IgG Production
Chemical class Allergens; Bee Venoms; Thiazides
DEA schedule Non-controlled
Marketing category UNAPPROVED HOMEOPATHIC
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2006-05-23
Route ORAL
Dosage form SOLUTION/ DROPS
Substance AMILORIDE; APIS MELLIFERA; BERBERIS VULGARIS FRUIT; HYDROCHLOROTHIAZIDE; SUS SCROFA PITUITARY GLAND; HIERACIUM PILOSELLA FLOWERING TOP; SOLIDAGO VIRGAUREA FLOWERING TOP; SPIRONOLACTONE
Why two NDCs? The FDA registers this code as 17089-260-18 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 17089-0260-18. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏭 Manufacturer & labeler

LabelerGuna spa
Labeler code17089
First marketedMay 2006
Product typeHuman Prescription Drug
Portfolio83 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

🧪 What is this product?

GUNA-DIUR is an unapproved homeopathic oral solution containing multiple ingredients traditionally used in homeopathic practice. The product includes potassium-sparing diuretics (amiloride and spironolactone) and a thiazide diuretic (hydrochlorothiazide), along with herbal extracts from berberis, hieracium, and solidago, plus apis mellifera (honeybee) and porcine pituitary gland. Homeopathic products are marketed based on traditional homeopathic uses rather than scientific evidence, and the FDA does not evaluate homeopathic drugs for safety or effectiveness.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 3K9958V90M
    A liquid solvent derived from fermentation or chemical synthesis. In medicines, alcohol dissolves active ingredients, helps preserve the product, and improves how the body absorbs certain drugs.

1 inactive ingredient listed in the exact product block matched to this NDC.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer mLPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Guna-Diur 4 [hp_X]/30mL; 2 [hp_X]/30mL; .3 g/30mL; 4 [hp_X]/30mL; 12 [hp_X]/30mL; .3 g/30mL; .3 g/30mLthis 17089-0260-18 Guna 1 bottle — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2006
On the market since
May 2006
📍
2026
Currently FDA-listed
20 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
17089-0260-18 You're viewing this 1 BOTTLE, DROPPER in 1 BOX (17089-260-18) / 30 mL in 1 BOTTLE, DROPPER 2018-12-21 Active

🧭 About this NDC listing & data coverage

Finished prescription product Homeopathic listing

About homeopathic listings

GUNA-DIUR amiloride - apis mellifera - berberis vulgaris fruit - hieracium pilosella flowering top - hydrochlorothiazide - solidago virgaurea flowering top - spironolactone - sus scrofa pituitary gland 4 [hp_X]/30mL; 2 [hp_X]/30mL; .3 g/30mL; 4 [hp_X]/30mL; 12 [hp_X]/30mL; .3 g/30mL; .3 g/30mL SOLUTION/ DROPS is listed under the homeopathic marketing category. An NDC listing in this category does not by itself establish FDA approval, and FDA does not evaluate homeopathic products for effectiveness. This page reports the listing data as published.

What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos — Not published for this NDC No photo available yet for this listing.
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Unapproved Homeopathic". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 17089-260-18, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 17089-0260-18, written without dashes as 17089026018. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 17089-0260-18, the first segment (17089) is the labeler code FDA assigned to Guna spa; the middle segment (0260) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (18) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Guna spa. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
Guna spa is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as a prescription product, so it is dispensed under a prescriber's order. Your pharmacist can tell you whether any over-the-counter forms of the same medication exist.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 Full prescribing information FDA SPL

The complete FDA label for this product — the official prescribing information, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration 💊 Dosage Forms and Strengths ⛔ Contraindications ⚠️ Warnings and Cautions 🤒 Adverse Reactions 🔄 Drug Interactions 👥 Use in Specific Populations 🆘 Overdosage 🧬 Clinical Pharmacology 📦 Storage and Handling 📋 Description 💬 Information for Patients
🎯 Indications and Usage 16 words ▾

1. INDICATIONS AND USAGE

1.1 Temporary relief of fluid retention

1.2 Tissue swelling and related disconforts

⏱️ Dosage and Administration 50 words ▾

2. DOSAGE AND ADMINISTRATION Adults: 20 drops in a little water, 2 times per day for an avarage of two months. Stop use and ask a doctor if symptoms persist more than 5 days. Administration may very according to individual needs. GUNA-DIUR may be used together with other homeopthic medicines.

💊 Dosage Forms and Strengths 55 words ▾

3. DOSAGE FORMS AND STRENGTHS 3.1. 30 ml Bottle dropper container contains: Active ingredients: Amiloride 4X 0.006 ml, Apis Mellifica 2X 0.626 ml, Berberis Vulgaris T 0.314 ml, Hydrochlorothiazide 4X 0.006 ml, Hypophysis 12X 6.314 ml, Mouse-Ear Hawkweed T 6.314 ml, Solidago Virgaurea T 0.314 ml, Spironolactone 4X 0.006 ml. Inactive Ingredient: Ethylic Alcohol 30%

⛔ Contraindications 27 words ▾

4. CONTRAINDICATIONS 4.1. There is no history of hypersensitivity to GUNA-DIUR. However, do not use if you are hypersensitive to any of the active ingredients of Guna-Diur.

⚠️ Warnings and Cautions 41 words ▾

5. WARNINGS AND PRECAUTIONS 5.1. GUNA-DIUR is contraindicated in patients with anuria and in patients with a history of hypersensitivity to Spironolactone, Amiloride, or Hydrocholorthiazide. 5.2. Use with caution in patients taking diuretic medications.

5.3Keep out of reach of children.

🤒 Adverse Reactions 11 words ▾

6. ADVERSE REACTIONS 6.1. None known (see CONTRAINDICATIONS for hypersensitivity information).

🔄 Drug Interactions 6 words ▾

7. DRUG INTERACTIONS 7.1. None Known

👥 Use in Specific Populations 91 words ▾

8. USE IN SPECIFIC POPULATIONS 8.1. Pregnancy : Pregnancy category C.

Animal reproduction studies have not been conducted with GUNA-DIUR. GUNA®- DIUR should not be given to a pregnant woman. 8.2.

Lactation : It is not known whether any of the ingredients in GUNA- DIUR are secreted in human milk. However, since many drugs are secreted in human milk, caution should be exercised when GUNA- DIUR is administered to a nursing woman. 8.3.

Pediatric use: Safety and effectiveness in pediatric patients have not been established. 8.4. Geriatric use : No restrictions.

🆘 Overdosage 5 words ▾

10. OVERDOSAGE 10.1. No Known.

🧬 Clinical Pharmacology 35 words ▾

12. CLINICAL PHARMACOLOGY 12.1. GUNA-DIUR exerts a diuretic effect. This is based on homeopthica Materia Medica and homeopathic principles. 12.2. Pharmacodynamics Not applicable to homeopthic medicinal products. 12.3. Pharmacokinetics Not applicable to homeopthic medicinal products.

📦 Storage and Handling 23 words ▾

16. HOW SUPPLIED/STORAGE AND HANDLING 16.1. NDC 17089-260-18 Oral Solution/Drops 30 mL 16.2. Store at 20-25°C (68-77° F). Excursions permitted between 15°-30°C (59°-86°F).

📋 Description 22 words ▾

11. DESCRIPTION 11. 1 GUNA-DIUR is a homeopathic medicine indicated for the temporary relief of fluid retention, tissue swelling and related disconforts.

💬 Information for Patients 19 words ▾

17. PATIENT COUNSELING INFORMATION 17.1. Patients should be informed about Homeopathy and the main differences with conventional clinical approaches.

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 17089-0259-18 · Guna 17089-0265-18 · Guna →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.