Home › NDC Lookup › Ingredients › Allium Cepa, Arsenicum Album, Bryonia Al... › 17312-0431-23
💨image loading
(from DailyMed)

Natural Relief Cold and Flu Plus Zinc Allium cepa, Arsenicum album, Bryonia alba, Eupatorium perfoliatum, Gelsemium sempervirens, Natrum muriaticum, Nux vomica, Silicea, Sulphur, Zincum gluconicum 6 [hp_X]/mL; 12 [hp_X]/mL; 12 [hp_X]/mL; 6 [hp_X]/mL; 12 [hp_X]/mL; 6 [hp_X]/mL; 6 [hp_X]/mL Spray — NDC 17312-431-23 (Billing 17312-0431-23)

by TRP Company · 1 BOTTLE, SPRAY in 1 CARTON / 20 mL in 1 BOTTLE, SPRAY

This is a package of Natural Relief Cold and Flu Plus Zinc Allium cepa, Arsenicum album, Bryonia alba, Eupatorium perfoliatum, Gelsemium sempervirens, Natrum muriaticum, Nux vomica, Silicea, Sulphur, Zincum gluconicum 6 [hp_X]/mL; 12 [hp_X]/mL; 12 [hp_X]/mL; 6 [hp_X]/mL; 12 [hp_X]/mL; 6 [hp_X]/mL; 6 [hp_X]/mL Spray from TRP Company, marketed since Aug 2024 and currently FDA-listed. It is this product's only package size.

NDC 17312-0431-23
🏷️ FDA NDC (as labeled) 17312-431-23 billing pads the product segment with a zero
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Oct 1, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 17312-431-23
Product NDC 17312-431
11-digit billing NDC 17312043123
UNII 8P2VLG2456, ETJ7Z6XBU4, 269XH13919, 451W47IQ8X, T7J046YI2B, R0519OZO3K +4 more
SPL Set ID 2a352cf2-48fb-4862-e063-6294a90a2eeb
Established class (EPC) Non-Standardized Plant Allergenic Extract
Physiologic effect Increased Histamine Release; Cell-mediated Immunity; Increased IgG Production
Chemical class Allergens; Plant Proteins; Seed Storage Proteins
DEA schedule Non-controlled
Marketing category UNAPPROVED HOMEOPATHIC
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2024-08-06
Route ORAL
Dosage form SPRAY
Substance ALLIUM CEPA WHOLE; SILICON DIOXIDE; STRYCHNOS NUX-VOMICA SEED; SODIUM CHLORIDE; BRYONIA ALBA ROOT; GELSEMIUM SEMPERVIRENS WHOLE; EUPATORIUM PERFOLIATUM FLOWERING TOP; ARSENIC TRIOXIDE; SULFUR; ZINC GLUCONATE
Why two NDCs? The FDA registers this code as 17312-431-23 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 17312-0431-23. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

Clinical

🧪 What is this product?

Natural Relief Cold and Flu Plus Zinc is an oral homeopathic spray containing ten plant and mineral ingredients. In homeopathic practice, these substances are traditionally used to address cold and flu symptoms. Homeopathic products are marketed based on traditional use rather than clinical evidence, and the FDA does not evaluate them for effectiveness. This product is not approved by the FDA in the traditional sense and is classified as an unapproved homeopathic drug.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer mLPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
17312-0431-23 You're viewing this Main listing 1 BOTTLE, SPRAY in 1 CARTON / 20 mL in 1 BOTTLE, SPRAY 2024-08-06 — Active

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Natural Relief Cold and Flu Plus Zinc 6 [hp_X]/mL; 12 [hp_X]/mL; 12 [hp_X]/mL; 6 [hp_X]/mL; 12 [hp_X]/mL; 6 [hp_X]/mL; 6 [hp_X]/mLthis 17312-0431-23 TRP 1 bottle — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2024
On the market since
Aug 2024
📍
2026
Currently FDA-listed
2 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerTRP Company
Labeler code17312
First marketedAug 2024
Product typeHuman Otc Drug
Portfolio31 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 When Using This Product 📄 Stop Use and Ask a Doctor If 🤰 If Pregnant or Breast-Feeding 📄 Keep Out of Reach of Children 📄 Questions or Comments 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 46 words ▾

INDICATIONS: Uses* • According to homeopathic indications, these ingredients provide temporary relief from symptoms of cold and flu such as: • Fever / chills • Runny nose. *These statements are based upon traditional homeopathic practice. They have not been reviewed by the Food and Drug Administration.

⏱️ Dosage and Administration 62 words ▾

DIRECTIONS: Suitable for adults and children ages 12 and over. Spray 2-3 times in mouth. • Keep in mouth for 15 seconds before swallowing. • Use up to 6 times a day as needed. • Use at least 10 minutes before or at least 10 minutes after eating or drinking. • Children under the age of 12: Consult a physician before use.

⚠️ Warnings 48 words ▾

WARNINGS: A PHYSICIAN SHOULD ALWAYS BE CONSULTED TO RULE OUT SERIOUS CAUSES . • This product is intended to complement, not replace, standard medical treatment. • Initial worsening of symptoms may occur. • This product is intended to be taken orally. Do not use in eyes or nose.

🧪 Active Ingredient 47 words ▾

ACTIVE INGREDIENTS: Allium cepa HPUS 6X, Arsenicum album HPUS 12X, Bryonia alba HPUS 12X, Eupatorium perfoliatum HPUS 6X, 12X, 30X, Gelsemium sempervirens HPUS 6X, 12X, 30X, Natrum muriaticum HPUS 6X, 12X, 30X, Nux vomica HPUS 12X, Silicea HPUS 12X, Sulphur HPUS 12X, Zincum gluconicum HPUS 4X, 6X

🧪 Inactive Ingredients 17 words ▾

INACTIVE INGREDIENTS: Alcohol 25%, Demineralized water, Fruit juice concentrates, Invert sugar, Natural flavor, Propylene glycol, Sodium bicarbonate.

🎯 Purpose 45 words ▾

USES: • According to homeopathic indications, these ingredients provide temporary relief from symptoms of cold and flu such as: • Fever / chills • Runny nose. *These statements are based upon traditional homeopathic practice. They have not been reviewed by the Food and Drug Administration.

📄 When Using This Product 23 words ▾

When using When using this product avoid contact with the eyes. Rinse right away with water if the product gets in your eye.

📄 Stop Use and Ask a Doctor If 17 words ▾

Stop use Stop use and ask a doctor if : • Symptoms last longer than 7 days.

🤰 If Pregnant or Breast-Feeding 13 words ▾

Pregnancy warning If pregnant or breast-feeding , ask a health professional before use.

📄 Keep Out of Reach of Children 27 words ▾

KEEP OUT OF REACH OF CHILDREN: Keep out of reach of children. In case of overdose, get medical help or call a Poison Control Center right away.

📄 Questions or Comments 15 words ▾

QUESTIONS: Questions or comments 1-888-969-6855 8 am to 4 pm EST; Monday - Friday www.thereliefproducts.com

📄 Package Label / Principal Display Panel 5 words ▾

PACKAGE LABEL DISPLAY: Carton Label

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

About this NDC listing & data coverage

Over-the-counter (OTC) product Homeopathic listing

About homeopathic listings

Natural Relief Cold and Flu Plus Zinc Allium cepa, Arsenicum album, Bryonia alba, Eupatorium perfoliatum, Gelsemium sempervirens, Natrum muriaticum, Nux vomica, Silicea, Sulphur, Zincum gluconicum 6 [hp_X]/mL; 12 [hp_X]/mL; 12 [hp_X]/mL; 6 [hp_X]/mL; 12 [hp_X]/mL; 6 [hp_X]/mL; 6 [hp_X]/mL SPRAY is listed under the homeopathic marketing category. An NDC listing in this category does not by itself establish FDA approval, and FDA does not evaluate homeopathic products for effectiveness. This page reports the listing data as published.

What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos — Not published for this NDC No photo available yet for this listing.
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Unapproved Homeopathic". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by TRP Company. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
TRP Company is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 17312-0430-15 · TRP 17312-0432-23 · TRP →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.