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Icy Hot Medicated No Mess Applicator Menthol .16 g/mL Liquid — NDC 41167-0091-00 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

Icy Hot Medicated No Mess Applicator Menthol .16 g/mL Liquid — NDC 41167-0091-0 (Billing 41167-0091-00)

by Chattem, Inc. · 1 BOTTLE, WITH APPLICATOR in 1 CARTON / 73 mL in 1 BOTTLE, WITH APPLICATOR

This is a package of Icy Hot Medicated No Mess Applicator Menthol .16 g/mL Liquid from Chattem, Inc., marketed since Dec 2009 and currently FDA-listed. It is the main listing for this product, which comes in 3 package sizes.

NDC 41167-0091-00
🏷️ FDA NDC (as labeled) 41167-0091-0 billing pads the package segment with a zero
This package
Contains73 mL in 1 bottle, with applicator Pack sizes3 compare ↓
Main listing for product 41167-0091 · Also comes in: 44.3 mL 41167-0091-1 3 bottles 41167-0091-2
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 41167-0091-0 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
41167 labeler · 0091 product · 0 package
Package marketed since
Dec 1, 2009
Sample package
No — commercial package
Listing certified through
Dec 31, 2026
Barcode (UPC-A, from the NDC)
3 4116700910 0
FDA record last changed
Jul 24, 2026
⚠️
Other active recalls for Menthol (different manufacturers) — 1 · tap to view
These affect other manufacturers’ products for the same ingredient — not necessarily the exact NDC on this page.
Class II · Mar 20, 2026 — This recall is being initiated following FDA's recommendation based on certain observations noted during an August 15, 2025, inspection of the manufacturing facility that may bear on product quality. (Xiamen Kang Zhongyuan Biotechnology Co., Ltd.) · FDA recall D-0458-2026
Each entry is an official FDA enforcement report — look up any recall number in the FDA recall database ↗

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 41167-0091-0
Product NDC 41167-0091
11-digit billing NDC 41167009100
NCPDP billing unit ML — per mL (volume)
RxCUI 866084
UNII L7T10EIP3A
Application # M017
SPL Set ID 4ce2b823-7ef5-4cca-a2d8-2fe781bc958e
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2009-12-01
Route TOPICAL
Dosage form LIQUID
Substance MENTHOL
Quick answers
  • RxCUI (RxNorm): 866084
Why two NDCs? The FDA registers this code as 41167-0091-0 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 41167-0091-00. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

Clinical

📗 Our plain-language guide HelloPharmacist
  • Mostly for temporary relief of minor aches and pains in muscles and joints, like those from arthritis, backache, strains, sprains and bruises. Some products are for other things, s...
  • It depends on the product. Many creams, gels and patches are limited to about 3 to 4 times a day, and patches also have a time limit, often 8 hours. Follow your product label and a...
  • A brief burning feeling can happen when you first apply it and usually fades in several days. But if you get severe burning pain, swelling or blistering, stop using it and call you...
  • No. Don't use menthol products with a heating pad, and avoid local heat or direct sunlight on the area. Rare cases of serious burns have been reported.
📖 Read our full Menthol guide →

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer mLPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 44.3 mL 3 bottles
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
41167-0091-00 You're viewing this Main listing 1 BOTTLE, WITH APPLICATOR in 1 CARTON / 73 mL in 1 BOTTLE, WITH APPLICATOR 2009-12-01 — Active
41167-0091-01 41167-0091-1 1 BOTTLE, WITH APPLICATOR in 1 CARTON / 44.3 mL in 1 BOTTLE, WITH APPLICATOR 2021-01-01 — Active
41167-0091-02 41167-0091-2 3 BOTTLE, WITH APPLICATOR in 1 BLISTER PACK / 73 mL in 1 BOTTLE, WITH APPLICATOR 2022-01-01 — Active

Pack size FAQ

What quantity is in this package?
This package is listed by the FDA — 1 bottle, with applicator in 1 carton / 73 ml in 1 bottle, with applicator.
What NDC number is used to bill for this package of Icy Hot Medicated No Mess Applicator Menthol .16 g/mL Liquid?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Walgreen Cool n Heat Maximum Strength Pain Relieving 160 mg/mL 00363-4837-01 Walgreen 1 bottle — — FDA listed —
Rite Aid Hot and Cold Roll On 16 g/100g 11822-1015-01 Rite 1 bottle — — FDA listed —
Kroger Cool and Heat Roll-On 16 g/100g 30142-0585-02 Kroger 1 bottle — — FDA listed —
TopCare Maximum Strength Pain Relieving Analgesic 160 mg/mL 36800-0894-01 Topco 1 bottle — — FDA listed —
Icy Hot Medicated No Mess Applicator .16 g/mLthis 41167-0091-00 Chattem, 1 bottle — — FDA listed —
Meijer Maximum Strength Pain Relieving Analgesic 160 mg/mL 41250-0350-01 Meijer 1 bottle — — FDA listed —
Zims Max Freeze Pro Formula 160 mg/mL 54273-0009-01 KOBAYASHI 1 bottle — — FDA listed —
DG Health Cold n Hot Pain Relieving Topical Analgesic 160 mg/mL 55910-0883-01 Dolgencorp 1 bottle — — FDA listed —
QC Cool and Heat Roll-On 16 g/100g 63868-0511-02 Chain 71 g — — FDA listed —
HealthWise Menthol Roll-On .16 g/mL 71101-0026-01 Veridian 1 bottle — — FDA listed —
TheraCare Roll-on Menthol 16% Pain Relief Liquid .16 g/mL 71101-0089-01 Veridian 1 bottle — — FDA listed —
DCH Labs Cool and Heat Roll-On 16 g/100g 72839-0101-02 Derma 71 g — — FDA listed —
Mineral Ice Extreme Dry Stick 16 g/100g 82632-0250-04 Carlin 1 cylinder — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2009
On the market since
Dec 2009
📍
2026
Currently FDA-listed
17 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 3K9958V90M
    A liquid solvent derived from fermentation or chemical synthesis. In medicines, alcohol dissolves active ingredients, helps preserve the product, and improves how the body absorbs certain drugs.
  • UNII S07O44R1ZM
    Capsaicin is a pungent compound from chili peppers. In topical medicines, it acts as an active warming or heat-producing agent rather than a traditional inactive ingredient, creating localized skin sensation.
  • UNII 59TL3WG5CO
    A synthetic polymer made by crosslinking acrylic acid with allyl sucrose. It thickens liquids, forms gels, and helps control how fast the medicine is released in your body.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • UNII 0RE8K4LNJS
    Isopropyl myristate is an oily liquid made from coconut or palm oil. It's used in medicines as an emollient and penetration enhancer to help the medicine absorb through skin or improve spreadability in topical products.
  • UNII 6DC9Q167V3
    Propylene glycol is a clear liquid derived from petroleum or vegetable sources. It acts as a solvent, humectant, and preservative in medicines, helping dissolve active ingredients and maintain product stability.
  • UNII 9O3K93S3TK
    Trolamine is an alkaline compound used as a pH buffer and emulsifier in medicines. It helps neutralize acids, stabilize formulations, and enable mixing of oil and water-based ingredients.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

8 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesacrylates/C10-30 alkyl acrylate crosspolymer, alcohol denat. (30%), capsaicin, glycerin, isopropyl myristate, propylene glycol, triethanolamine, water Close cap tightly after use.

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerChattem, Inc.
FDA applicationM017 (OTC MONOGRAPH DRUG)
Labeler code41167
First marketedDec 2009
Product typeHuman Otc Drug
Portfolio157 products on file

More NDCs from Chattem, Inc. labeler code 41167

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Do Not Use 📄 When Using This Product 📄 Stop Use and Ask a Doctor If 🤰 If Pregnant or Breast-Feeding 📄 Keep Out of Reach of Children 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 13 words ▾

Uses temporarily relieves minor pain associated with: arthritis simple backache strains sprains bruises

⏱️ Dosage and Administration 55 words ▾

Directions ■ adults and children 12 years of age and older: ■ apply a thin layer to affected area not more than 3 to 4 times daily ■ massage until thoroughly absorbed into skin ■ wash hands thoroughly with soap and water after each use ■ children under 12 years of age: ask a doctor

⚠️ Warnings 181 words ▾

Warnings For external use only Flammable: keep away from heat and open flame. Do not use ■ on wounds or on irritated or damaged skin ■ with a heating pad When using this product ■ use only as directed ■ do not bandage tightly ■ avoid contact with eyes and mucous membranes ■ do not expose the area to local heat or to direct sunlight ■ rare cases of serious burns have been reported with products of this type ■ a transient burning sensation may occur upon application but generally disappears in several days ■ avoid applying into skin folds Stop use and ask a doctor if ■ condition worsens or symptoms persist for more than 7 days ■ symptoms clear up and occur again within a few days ■ redness is present or excessive skin irritation occurs ■ you experience severe burning pain, swelling, or blistering where the product was applied If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

🧪 Active Ingredient 4 words ▾

Active ingredient Menthol 16%

🧪 Inactive Ingredients 22 words ▾

Inactive ingredients acrylates/C10-30 alkyl acrylate crosspolymer, alcohol denat. (30%), capsaicin, glycerin, isopropyl myristate, propylene glycol, triethanolamine, water Close cap tightly after use.

🎯 Purpose 3 words ▾

Purpose Topical analgesic

📄 Do Not Use 17 words ▾

Do not use ■ on wounds or on irritated or damaged skin ■ with a heating pad

📄 When Using This Product 70 words ▾

When using this product ■ use only as directed ■ do not bandage tightly ■ avoid contact with eyes and mucous membranes ■ do not expose the area to local heat or to direct sunlight ■ rare cases of serious burns have been reported with products of this type ■ a transient burning sensation may occur upon application but generally disappears in several days ■ avoid applying into skin folds

📄 Stop Use and Ask a Doctor If 52 words ▾

Stop use and ask a doctor if ■ condition worsens or symptoms persist for more than 7 days ■ symptoms clear up and occur again within a few days ■ redness is present or excessive skin irritation occurs ■ you experience severe burning pain, swelling, or blistering where the product was applied

🤰 If Pregnant or Breast-Feeding 10 words ▾

If pregnant or breast-feeding, ask a health professional before use.

📄 Keep Out of Reach of Children 19 words ▾

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

📄 Package Label / Principal Display Panel 38 words ▾

Principal Display Panel ICY HOT ® ORIGINAL N O- MESS ROLL ON PAIN RELIEF 16% MENTHOL 2.5 fl oz ( 73 m L) ICY HOT® ORIGINAL NO-MESS ROLL ON PAIN RELIEF 16% MENTHOL 2.5 fl oz (73 mL)

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Icy Hot Medicated No Mess Applicator (this brand).

Top reported reactions

Pain119
Dyspnoea87
Pruritus85
Fatigue84
Erythema77
Dizziness68
Headache67

Age at onset

Infant1
Child1
Adolescent1
Adult176
Elderly105

Reporter sex

1,269 reports
Male · 36%
Female · 64%
Unknown · 0%

Serious outcomes

Hospitalization336
Death126
Life-threatening45
Disabling30
Reports over time (by year) — tap or hover for the count & year
2019 2021 2023 2026 190 0
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Chattem, Inc.. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 2 other package presentations of this same product, including 1 bottle (41167-0091-01), 3 bottles (41167-0091-02). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Chattem, Inc. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 41167-0088-01 · Chattem, 41167-0092-00 · Chattem, →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.