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Eagle Brand Medicated Plaster Extra Strength menthol, capsaicin .025 g/100g; 1.25 g/100g Patch — NDC 43405-0301-05 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

Eagle Brand Medicated Plaster Extra Strength menthol, capsaicin .025 g/100g; 1.25 g/100g Patch — NDC 43405-301-05 (Billing 43405-0301-05)

by Borden Company (Private) Limited · 5 PATCH in 1 POUCH / 11 g in 1 PATCH

This is a package of Eagle Brand Medicated Plaster Extra Strength menthol, capsaicin .025 g/100g; 1.25 g/100g Patch from Borden Company (Private) Limited, marketed since Feb 2025 and currently FDA-listed. It is this product's only package size.

NDC 43405-0301-05
🏷️ FDA NDC (as labeled) 43405-301-05 billing pads the product segment with a zero
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 43405-301-05 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
43405 labeler · 301 product · 05 package
Package marketed since
Feb 1, 2025
Sample package
No — commercial package
Listing certified through
Dec 31, 2026
Barcode (UPC-A, from the NDC)
3 4340530105 2
FDA record last changed
Jul 24, 2026

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 43405-301-05
Product NDC 43405-301
11-digit billing NDC 43405030105
RxCUI 853136
UNII S07O44R1ZM, L7T10EIP3A
Application # 505G(a)(3)
SPL Set ID 2f2a4080-d538-1c6a-e063-6394a90ae51c
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2025-02-01
Route TOPICAL
Dosage form PATCH
Substance CAPSAICIN; MENTHOL
Quick answers
  • RxCUI (RxNorm): 853136
Why two NDCs? The FDA registers this code as 43405-301-05 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 43405-0301-05. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Capsaicin and similar agents class.

Drug family (ATC) Capsaicin and similar agents, Other local anesthetics
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

🧪 What is this product?

Eagle Brand Medicated Plaster Extra Strength is a topical patch that contains menthol and capsaicin as active ingredients. This product is an over-the-counter monograph drug, meaning it is regulated under an established FDA rule-book for topical analgesic patches rather than as an individually approved application. Menthol and capsaicin are commonly used in topical products to produce a cooling or warming sensation and are typically applied to the skin over areas of minor muscle or joint discomfort.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
43405-0301-05 You're viewing this Main listing 5 PATCH in 1 POUCH / 11 g in 1 PATCH 2025-02-01 — Active

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Eagle Brand Medicated Plaster Extra Strength .025 g/100g; 1.25 g/100gthis 43405-0301-05 Borden 5 patches — — FDA listed —
Salonpas pain relieving hot .025 g/100g; 1.25 g/100g 46581-0871-06 Hisamitsu 6 patches — — FDA listed —
HealthWise Pain Relief Gel Patch .025 g/100g; 1.25 g/100g 71101-0105-01 Veridian 3 patches — — FDA listed —
AsperFlex HOT .025 g/100g; 1.25 g/100g 71399-4439-06 Akron 6 patches — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2025
On the market since
Feb 2025
📍
2026
Currently FDA-listed
1 year listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII K679OBS311
    Carboxymethylcellulose sodium is a plant-derived thickening agent made from cellulose. In medicines, it acts as a binder to hold ingredients together, a disintegrant to help the tablet break apart, or a thickener in liquids.
  • UNII DO250MG0W6
    A mineral compound containing aluminum that acts as an antacid and buffering agent. It helps neutralize stomach acid and is used as a pH buffer to stabilize the medicine's formulation.
  • UNII 147D247K3P
    Ethylhexylglycerin is a synthetic preservative used to prevent bacteria and mold from growing in medicines and personal care products. It helps keep the product safe and stable throughout its shelf life.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • UNII 603P14DHEB
    A synthetic antimicrobial chemical used as a preservative in topical and cosmetic formulations. It prevents bacterial and fungal growth in products to maintain stability and safety during storage and use.
  • UNII 24H4NWX5CO
    Kaolin is a naturally occurring clay mineral. It's used in tablets and capsules as a filler and absorbent to add bulk, improve texture, and help bind ingredients together.
  • UNII T5L8T28FGP
    Mineral oil is a clear, odorless liquid derived from crude oil. It acts as a lubricant and emollient in medications, helping pills slide smoothly during manufacturing and aiding moisture retention in topical products.
  • UNII 4T6H12BN9U
    Petrolatum is a purified mineral oil-based jelly derived from petroleum. In medicines, it acts as an emollient, lubricant, and moisture barrier to soften skin, reduce friction, and help prevent water loss from formulations.
  • UNII HIE492ZZ3T
    Phenoxyethanol is a synthetic preservative and antimicrobial agent used to prevent bacterial and fungal growth in medicines and cosmetic products, extending shelf life and maintaining product safety.
  • UNII 73861X4K5F
    A synthetic polymer used as a binder and thickening agent in tablets and capsules. It helps hold ingredients together and can modify how quickly the medicine dissolves and is absorbed in your body.
  • UNII 6OZP39ZG8H
    Polysorbate 80 is a synthetic emulsifier derived from sorbitol and oleic acid. It helps mix oil and water-based ingredients together in medications and improves how the product disperses in the body.
  • UNII FZ989GH94E
    Povidone is a synthetic polymer made from a plastic-like material. It acts as a binder to hold tablet ingredients together and as a disintegrant to help the tablet break apart in your stomach so the medicine can be absorbed.
  • UNII 6DC9Q167V3
    Propylene glycol is a clear liquid derived from petroleum or vegetable sources. It acts as a solvent, humectant, and preservative in medicines, helping dissolve active ingredients and maintain product stability.
  • UNII 05I15JNI2J
    A synthetic polymer that absorbs and holds moisture. Used in tablets and capsules as a super-disintegrant to help the medicine break apart quickly when swallowed, allowing faster drug release.
  • UNII RRX6A4PL3C
    A naturally occurring organic acid found in grapes and tamarinds. It functions as a buffer to control acidity, a flavor enhancer, and sometimes a chelating agent to improve stability in liquid and solid medications.
  • UNII 15FIX9V2JP
    Titanium dioxide is a bright white mineral powder commonly used as a colorant and opacifying agent. It makes pills and tablets white or lighter in color and helps make coatings non-transparent.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

17 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesCarboxymethylcellulose sodium, Dihydroxyaluminum aminoacetate, Glycerin, Iodopropynyl butylcarbamate, Kaolin, Mineral oil, Petrolatum, Phenoxyethanol, Polyacrylic acid, Polysorbate, Povidone, Propylene glycol, Sodium polyacrylate, Tartaric acid, Titanium dioxide, Water, 3-(2-ethylhexyloxy)propane-1,2-diol

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerBorden Company (Private) Limited
FDA application505G(a)(3) (OTC MONOGRAPH DRUG)
Labeler code43405
First marketedFeb 2025
Product typeHuman Otc Drug
Portfolio21 products on file

More NDCs from Borden Company (Private) Limited labeler code 43405

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 When Using This Product 📄 Stop Use and Ask a Doctor If 🤰 If Pregnant or Breast-Feeding 📄 Keep Out of Reach of Children 📄 Other Information 📄 Questions or Comments 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 26 words ▾

Uses For temporary relief of minor aches and pains of muscles and joints associated with ▪ simple backache ▪ arthritis ▪ strains ▪ bruises ▪ sprains.

⏱️ Dosage and Administration 57 words ▾

Directions Adults and children 12 years of age and above: ▪ Clean and dry affected area before applying. ▪ Do not leave the patch on skin for more than 8 hours. ▪ Apply to affected area not more than 3 to 4 times daily. Children under 12 years of age: ▪ Do not use, consult a doctor.

⚠️ Warnings 132 words ▾

Warnings For external use only When using this product ▪ Avoid contact with eyes or on mucous membranes. ▪ Do not apply to wounds or damaged skin. ▪ Do not bandage tightly. ▪ Do not apply wiht external heat, such as heating pad. ▪ Do not use otherwise than as directed Stop use and ask doctor if ▪ Condition worsens. ▪ Symptoms persist for more than 7 days. ▪ Clear up and occur again within a few days, discontinue use of this product and consult a doctor. ▪ Skin reactions such as redness, itching, rash, excessive irritation, burning sensation, swelling or blistering occurs.

If pregnant or breast-feeding Ask a health professional before use. Keep out of reach of children If swallowed, get medical help or contact a Poison Control Centre right away.

🧪 Active Ingredient 9 words ▾

Active ingredients Menthol 1.25% Capsaicin 0.025% Purpose External Analgesic

🧪 Inactive Ingredients 28 words ▾

Inactive ingredients Carboxymethylcellulose sodium, Dihydroxyaluminum aminoacetate, Glycerin, Iodopropynyl butylcarbamate, Kaolin, Mineral oil, Petrolatum, Phenoxyethanol, Polyacrylic acid, Polysorbate, Povidone, Propylene glycol, Sodium polyacrylate, Tartaric acid, Titanium dioxide, Water, 3-(2-ethylhexyloxy)propane-1,2-diol

🎯 Purpose 3 words ▾

Purpose External Analgesic

📄 When Using This Product 46 words ▾

When using this product ▪ Avoid contact with eyes or on mucous membranes. ▪ Do not apply to wounds or damaged skin. ▪ Do not bandage tightly. ▪ Do not apply wiht external heat, such as heating pad. ▪ Do not use otherwise than as directed

📄 Stop Use and Ask a Doctor If 52 words ▾

Stop use and ask doctor if ▪ Condition worsens. ▪ Symptoms persist for more than 7 days. ▪ Clear up and occur again within a few days, discontinue use of this product and consult a doctor. ▪ Skin reactions such as redness, itching, rash, excessive irritation, burning sensation, swelling or blistering occurs.

🤰 If Pregnant or Breast-Feeding 10 words ▾

If pregnant or breast-feeding Ask a health professional before use.

📄 Keep Out of Reach of Children 19 words ▾

Keep out of reach of children If swallowed, get medical help or contact a Poison Control Centre right away.

📄 Other Information 15 words ▾

Other information ▪ Avoid storing product in direct sunlight. ▪ Protect product from excessive moisture.

📄 Questions or Comments 16 words ▾

Questions? If there are any questions or to report serious side effects, call 1-800-777-6717 or 1-800-645-0769.

📄 Package Label / Principal Display Panel 12 words ▾

Package Label 5 Patches in 1 Pouch NDC: 43405-301-05 5 patches UB

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Menthol, capsaicin — the ingredient across all brands.

Top reported reactions

Headache4
Blood Pressure Increased3
Chest Pain3
Depression3
Diarrhoea3
Fatigue3
Hypersensitivity3

Age at onset

Adult5

Reporter sex

39 reports
Male · 29%
Female · 69%
Unknown · 3%

Serious outcomes

Hospitalization10
Life-threatening2
Death1
Reports over time (by year) — tap or hover for the count & year
2024 2025 2026 3 0
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Borden Company (Private) Limited. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
Borden Company (Private) Limited is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 43405-0300-05 · Borden 43406-0001-01 · Natural →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.