Home › NDC Lookup › Ingredients › Drosera (Rotundifolia), Coccus Cacti, Sp... › 43857-0548-01
Cough Syrup Formula Drosera (Rotundifolia), Coccus Cacti, Spongia Tosta, Belladonna, Cuprum Aceticum, Kali Carbonicum, Mentha Piperita, Phosphorus 4 [hp_X]/mL; 5 [hp_X]/mL; 5 [hp_X]/mL; 6 [hp_X]/mL; 12 [hp_X]/mL; 12 [hp_X]/mL; 12 [hp_X]/mL Liquid, 120 mL — NDC 43857-0548-01 package photo

Cough Syrup Formula Drosera (Rotundifolia), Coccus Cacti, Spongia Tosta, Belladonna, Cuprum Aceticum, Kali Carbonicum, Mentha Piperita, Phosphorus 4 [hp_X]/mL; 5 [hp_X]/mL; 5 [hp_X]/mL; 6 [hp_X]/mL; 12 [hp_X]/mL; 12 [hp_X]/mL; 12 [hp_X]/mL Liquid, 120 mL

by BioActive Nutritional, Inc. · 120 mL in 1 BOTTLE (43857-0548-1)
NDC 43857-0548-01
🏷️ FDA NDC (as labeled) 43857-0548-1 billing pads the package segment with a zero
OTC On market Non-controlled
🗂️ Data synced Sep 17, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 43857-0548-1
Product NDC 43857-0548
11-digit billing NDC 43857054801
UNII QR44N9XPJQ, LZB7TFX1LT, 1PIP394IID, WQZ3G9PF0H, 39M11XPH03, BQN1B9B9HA +2 more
SPL Set ID ade129ac-3a50-47fe-87be-8efc3a64d2cd
DEA schedule Non-controlled
Marketing category UNAPPROVED HOMEOPATHIC
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2020-02-25
Route ORAL
Dosage form LIQUID
Substance DROSERA ROTUNDIFOLIA WHOLE; PROTORTONIA CACTI; SPONGIA OFFICINALIS SKELETON, ROASTED; ATROPA BELLADONNA; CUPRIC ACETATE; POTASSIUM CARBONATE; MENTHA X PIPERITA WHOLE; PHOSPHORUS
Why two NDCs? The FDA registers this code as 43857-0548-1 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 43857-0548-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏭 Manufacturer & labeler

LabelerBioActive Nutritional, Inc.
Labeler code43857
First marketedFeb 2020
Product typeHuman Otc Drug
Portfolio315 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

🧪 What is this product?

This is an unapproved homeopathic liquid cough syrup taken by mouth. It contains multiple plant and mineral ingredients including drosera (sundew), coccus cacti (cochineal insect), roasted spongia (sea sponge), belladonna, cuprum aceticum (copper salt), potassium carbonate, peppermint, and phosphorus. In homeopathic practice, these ingredients are traditionally used to address cough and related respiratory symptoms. Homeopathic products are marketed based on traditional use rather than FDA evaluation for effectiveness.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 3K9958V90M
    A liquid solvent derived from fermentation or chemical synthesis. In medicines, alcohol dissolves active ingredients, helps preserve the product, and improves how the body absorbs certain drugs.
  • UNII 6Y89129C8H
    Anise oil is a natural flavoring extract from anise seeds. It's added to medicines to improve taste and mask bitter or unpleasant flavors, making them easier to take.
  • UNII FV3431923Z
    A natural flavoring derived from berry fruits. Added to medicines to improve taste and make them more pleasant to take.
  • UNII BJ7YPN79A1
    A natural extract from Icelandic moss, a lichen used in traditional herbal preparations. It functions as a thickening agent, binder, and skin-conditioning ingredient in topical and oral formulations.
  • UNII FGL3685T2X
    Chamomile is a plant extract used in medications as a flavoring agent and for its mild soothing properties in formulations. It helps improve taste and aroma of the medicine.
  • UNII BUC5I9595W
    A natural flavoring derived from cherry fruit that gives the medicine its cherry taste. It helps mask bitter drug flavors and makes the medication more pleasant to take.
  • UNII IY9XDZ35W2
    Dextrose is a simple sugar derived from corn or other sources. It serves as a filler and sweetener in medicines to add bulk, improve taste, and help stabilize the medication's form.
  • UNII FS7G8S6PJ8
    Echinacea angustifolia is a plant extract from the narrow-leaved coneflower. It's used in some formulations as a natural flavoring agent or to support the product's intended herbal composition.
  • UNII 2R04ONI662
    Eucalyptus oil is a fragrant liquid extracted from eucalyptus tree leaves. It's used in medicines as a flavor, scent, or soothing agent in topical products and cough preparations.
  • UNII Y9H1V576FH
    Honey is a natural sweetener made by bees from flower nectar. In medicines, it adds sweetness to improve taste and may help soothe throat irritation in lozenges or syrups.
  • UNII 7CVR7L4A2D
    A starch-derived carbohydrate produced by breaking down corn, potato, or tapioca starch. It functions as a filler and binder to give the medicine bulk and texture, and sometimes as a mild sweetener or texture enhancer in powders and tablets.
  • UNII 12X9JI52BS
    A plant extract from common mallow flowers used as a natural colorant and flavoring agent. It may add color, taste, or soothing properties to the medicine's appearance and flavor.
  • UNII 7DC28K241X
    Plantago major leaf is a plant-derived ingredient used as a natural binder and thickening agent. It helps hold tablet ingredients together and may improve the product's texture or consistency.
  • UNII GRX3499643
    A plant extract from common thyme used as a natural flavoring agent and preservative in medicines. It adds taste and helps prevent spoilage of the product.
  • UNII 4JS0838828
    A plant extract from red clover flowers used in herbal or natural formulations. It may serve as an active botanical ingredient or flavor/color component, though its specific role depends on the product's intended use.
  • UNII X6M0DRN46Q
    Urtica dioica leaf is a plant extract commonly used as a natural ingredient in dietary supplements and herbal formulations. It serves as an active botanical component intended to provide nutritional or herbal properties to the product.
  • UNII ANX0EG34JE
    A plant-derived ingredient from mullein leaves. It's used in some formulations as a natural extract to help with texture, consistency, or as a flavoring agent in medicines.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

18 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesDemineralized Water, Dextrose, Essential Oil Blend [Anise (Seed), Eucalyptus (Leaf)], Ethanol, 10% Herbal Extracts [Chamomile (Flower), Echinacea Angustifolia (leaf, stem), High Mallow (Flower), Iceland Moss (Whole Plant), Mullein (Leaf), Plantain (Leaf), Red Clover (Flower), Stinging Nettle (Leaf), Thyme (Leaf)], Honey, Natural Cherry Flavor, Natural Mixed Berry Flavor.

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer mLPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Cough Syrup Formula 4 [hp_X]/mL; 5 [hp_X]/mL; 5 [hp_X]/mL; 6 [hp_X]/mL; 12 [hp_X]/mL; 12 [hp_X]/mL; 12 [hp_X]/mLthis 43857-0548-01 BioActive 120 ml — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2020
On the market since
Feb 2020
📍
2026
Currently FDA-listed
6 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
43857-0548-01 You're viewing this 120 mL in 1 BOTTLE (43857-0548-1) 2020-02-25 Active

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product Homeopathic listing

About homeopathic listings

Cough Syrup Formula Drosera (Rotundifolia), Coccus Cacti, Spongia Tosta, Belladonna, Cuprum Aceticum, Kali Carbonicum, Mentha Piperita, Phosphorus 4 [hp_X]/mL; 5 [hp_X]/mL; 5 [hp_X]/mL; 6 [hp_X]/mL; 12 [hp_X]/mL; 12 [hp_X]/mL; 12 [hp_X]/mL LIQUID is listed under the homeopathic marketing category. An NDC listing in this category does not by itself establish FDA approval, and FDA does not evaluate homeopathic products for effectiveness. This page reports the listing data as published.

What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Unapproved Homeopathic". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 43857-0548-1, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 43857-0548-01, written without dashes as 43857054801. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 43857-0548-01, the first segment (43857) is the labeler code FDA assigned to BioActive Nutritional, Inc.; the middle segment (0548) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (01) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by BioActive Nutritional, Inc.. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
BioActive Nutritional, Inc. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 21 words ▾

INDICATIONS: For temporary relief of irritable, dry, tickling cough associated with flu, spasmodic cough worse at night & cough with expectorations.

⏱️ Dosage and Administration 26 words ▾

DIRECTIONS: SHAKE WELL. 1 teaspoon every 2-3 hours, children under 12, 1/2 adult dose. Consult a physician for use in children under 12 years of age.

⚠️ Warnings 49 words ▾

WARNINGS: If pregnant or breast-feeding, ask a health care professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Do not use if tamper evident seal is broken or missing. Store in cool, dry place.

🧪 Active Ingredient 24 words ▾

ACTIVE INGREDIENTS: Drosera (Rotundifolia) 4X, Coccus Cacti 5X, Spongia Tosta 5X, Belladonna 6X, Cuprum Aceticum 12X, Kali Carbonicum 12X, Mentha Piperita 12X, Phosphorus 12X.

🧪 Inactive Ingredients 49 words ▾

INACTIVE INGREDIENTS: Demineralized Water, Dextrose, Essential Oil Blend [Anise (Seed), Eucalyptus (Leaf)], Ethanol, 10% Herbal Extracts [Chamomile (Flower), Echinacea Angustifolia (leaf, stem), High Mallow (Flower), Iceland Moss (Whole Plant), Mullein (Leaf), Plantain (Leaf), Red Clover (Flower), Stinging Nettle (Leaf), Thyme (Leaf)], Honey, Natural Cherry Flavor, Natural Mixed Berry Flavor.

🎯 Purpose 21 words ▾

INDICATIONS: For temporary relief of irritable, dry, tickling cough associated with flu, spasmodic cough worse at night & cough with expectorations.

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 43857-0547-01 · BioActive 43857-0549-01 · BioActive →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.