Home › NDC Lookup › Ingredients › Water, Benzalkonium Chloride, Isopropyl... › 49687-0021-00
Large ANSI First Aid Kit WATER, BENZALKONIUM CHLORIDE, ISOPROPYL ALCOHOL, BACITRACIN ZINC, NEOMYCIN SULFATE, POLYMYXIN B SULFATE, LIDOCAINE HYDROCHLORIDE Kit — NDC 49687-0021-00 package photo

Large ANSI First Aid Kit WATER, BENZALKONIUM CHLORIDE, ISOPROPYL ALCOHOL, BACITRACIN ZINC, NEOMYCIN SULFATE, POLYMYXIN B SULFATE, LIDOCAINE HYDROCHLORIDE Kit

by CMC Group, Inc. · 1 KIT in 1 KIT (49687-0021-0) * 10 PACKAGE in 1 KIT (49687-0013-0) / .9 g in 1 PACKAGE * 6 PACKAGE in 1 BOX (49687-0015-1) / .9 g in 1 PACKAGE * 10 POUCH in 1 KIT (49687-0014-0) / .9 g in 1 POUCH * 1 TUBE in 1 BOX (49687-0010-1) / 30 mL in 1 TUBE
NDC 49687-0021-00
🏷️ FDA NDC (as labeled) 49687-0021-0 billing pads the package segment with a zero
OTC On market Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 49687-0021-0
Product NDC 49687-0021
11-digit billing NDC 49687002100
RxCUI 204602, 581660, 797544, 1012100, 1038558, 1053429
Application # M003
SPL Set ID fa8578c2-a0bc-4e2e-a4f9-d48debfff378
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2016-08-09
Route OPHTHALMIC
Dosage form KIT
Why two NDCs? The FDA registers this code as 49687-0021-0 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 49687-0021-00. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Other antibiotics for topical use class.

Drug family (ATC) Other antibiotics for topical use, Other antibacterials, Antibiotics
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerCMC Group, Inc.
FDA applicationM003 (OTC MONOGRAPH DRUG)
Labeler code49687
First marketedAug 2016
Product typeHuman Otc Drug
Portfolio6 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

🧪 What is this product?

This is an over-the-counter first aid kit for ophthalmic (eye) use, marketed under FDA's OTC monograph rules. It contains several active ingredients commonly used in eye care products: benzalkonium chloride functions as an antimicrobial preservative, isopropyl alcohol serves as an antiseptic, bacitracin zinc, neomycin sulfate, and polymyxin B sulfate are topical antibiotics typically included to help prevent infection in minor cuts and scrapes, and lidocaine hydrochloride is a local anesthetic commonly used to numb minor pain. The kit also includes water as a base or rinse component.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

From the label’s inactive-ingredient sectionBenzalkonium chloride, sodium chloride Purified water. Mineral oil, petrolatum, purified water glycerin monostearate, glycerol, purified water Carbomer, propylene glycol, purified water, titanium dioxide

This is label-wide narrative text, not a normalized exact-product ingredient list. A label can cover multiple strengths or packages.

Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Large ANSI First Aid Kitthis 49687-0021-00 CMC 1 kit — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2016
On the market since
Aug 2016
📍
2026
Currently FDA-listed
10 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
49687-0021-00 You're viewing this 1 KIT in 1 KIT (49687-0021-0) * 10 PACKAGE in 1 KIT (49687-0013-0) / .9 g in 1 PACKAGE * 6 PACKAGE in 1 BOX (49687-0015-1) / .9 g in 1 PACKAGE * 10 POUCH in 1 KIT (49687-0014-0) / .9 g in 1 POUCH * 1 TUBE in 1 BOX (49687-0010-1) / 30 mL in 1 TUBE 2016-08-09 Active

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product Kit / multi-component package

Kit / multi-component package

This NDC identifies a kit — a package containing more than one component. Structured data (pricing, ingredients, equivalents) is often reported per component rather than for the kit NDC itself, which can make this page look thinner than the components' own pages.

What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 49687-0021-0, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 49687-0021-00, written without dashes as 49687002100. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 49687-0021-00, the first segment (49687) is the labeler code FDA assigned to CMC Group, Inc.; the middle segment (0021) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (00) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by CMC Group, Inc.. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
CMC Group, Inc. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 100 words ▾

Use For cleansing the eye to help relieve irritation or burning by removing loose foreign material

Use: For Professional and Hospital use. Helps prevent infection. Antiseptic cleansing of face, hands and body without soap and water.

Use: For preparation of the skin before injection.

Use First aid to help prevent infection in minor cuts, scrapes, and burns.

Uses First aid to help prevent infection in minor cuts, scrapes, and burns. For the temporary relief of pain and itching associated with minor burns , minor cuts, and scrapes

Uses For handwashing to decrease bacteria on the skin Recommended for repeated use.

⏱️ Dosage and Administration 147 words ▾

Directions • Flush the affected eye as needed, controlling the rate of flow of solution by pressure on the bottle

Directions: Tear open packet, unfold towelette and use to cleanse desired skin area. Discard towelette appropriately after single use.

Directions: Wipe injection site vigorously and discard.

Directions • Clean the affected area. • Apply a small amount of this product (an amount equal to the surface area of the tip of a finger) on the area 1 to 3 times daily. • May be covered with a sterile bandage.

Directions Clean the affected area Adults and children 2 years of age and older: Apply a small amount of this product to affected area not more than 3 times daily Children under 2 years of age: consult a doctor May be covered with a sterile bandage

Directions Wet hands thoroughly with product and allow to dry without wiping.

⚠️ Warnings ~2 min read ▾

Warnings For external use only. Do not use if solution changes color or becomes cloudy When using this product • to avoid contamination, do not touch tip of container to any surface • do not reuse • once opened, discard • obtain immediate medical treatment for all open wounds in or near the eyes Stop use and ask a doctor if • you experience: • eye pain • changes in vision • continued redness • irritation of the eye • condition worsens or persists Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Warnings: For external use only. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away. If unusual redness, swelling or other symptoms occur, consult a physician immediately. Do not use: In the eyes, or over large areas of the body.

Warnings: For external use only. Flammable - keep away from fire or flame. Do not use: with electrocautery, in the eyes Stop use if irritation and redness develop. If condition persists for more than 72 hours, consult your doctor. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Warnings For external use only Do not use • in the eyes • over large areas of the body • if you are allergic to any of the ingredient • longer than 1 week unless directed by a doctor. Ask a doctor before use if you have • deep or punture wounds • animal bites • serious burns. Stop use and ask a doctor if • the condition persists or gets worse • a rash or other allergic reaction develops.

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Warnings For external use only. Do not use • in the eyes • over large areas of the body • in large quantities • over raw surfaces or blistered areas • longer than 1 week unless directed by a doctor Ask a doctor before use if you have • deep or puncture wounds • animal bites • serious burns. Stop use and ask a doctor if • the condition persists or gets worse • symptoms persist for more than 7 days or clear up and occur again within a few days Keep out of reah of children.

If swallowed, get medical help or contact a Poison Control Center right away.

Warnings Flammable, keep away from fire or flame For external use only. Do not use in the eyes. Stop use and ask a doctor if irritation and redness develop condition persists for more than 72 hours Keep out of reach children. If swallowed, get medical help or contact a Poison Control Center right away.

🧪 Active Ingredient 71 words ▾

Active ingredient Purified Water 99.1% Purpose Eyewash

Active Ingredient: Benzalkonium Chloride 0.13% Purpose: First Aid Antiseptic

Active Ingredient: Isopropyl Alcohol, 70% v/v Purpose: Antiseptic

Active ingredients (in each gram) Bacitracin zinc (bacitracin 400 units) Neomycin sulfate (neomycin 3.5mg) Polymyxin B sulfate (polymyxin B 5,000 units) Purpose First aid antibiotic

Active ingredients Benzalkonium chloride 0.13% Lidocaine hydrochloride 0.5% Purpose First aid antiseptic Pain relieving cream

Active ingredient Ethyl alcohol 62% Purpose Antiseptic

🧪 Inactive Ingredients 37 words ▾

Inactive ingredients Benzalkonium chloride, sodium chloride

Inactive ingredient: Purified water.

Inactive ingredient: Purified water.

Inactive ingredients Mineral oil, petrolatum, purified water

Inactive ingredients glycerin monostearate, glycerol, purified water

Inactive ingredients Carbomer, propylene glycol, purified water, titanium dioxide

🎯 Purpose 21 words ▾

Purpose Eyewash

Purpose: First Aid Antiseptic

Purpose: Antiseptic

Purpose First aid antibiotic

Purpose First aid antiseptic Pain relieving cream

Purpose Antiseptic

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 49687-0020-00 · CMC 49687-0029-00 · CMC →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.