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CVS Cold and Hot Pain Relief Dry Lidocaine, Menthol 10 mg/g; 40 mg/g Spray, 113 g — NDC 51316-0483-04 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

CVS Cold and Hot Pain Relief Dry Lidocaine, Menthol 10 mg/g; 40 mg/g Spray, 113 g — NDC 51316-483-04 (Billing 51316-0483-04)

by CVS Pharmacy · 113 g in 1 CAN

This is a package of 113 g of CVS Cold and Hot Pain Relief Dry Lidocaine, Menthol 10 mg/g; 40 mg/g Spray from CVS Pharmacy, marketed since Feb 2026 and currently FDA-listed. It is this product's only package size.

NDC 51316-0483-04
🏷️ FDA NDC (as labeled) 51316-483-04 billing pads the product segment with a zero
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 8, 2026 · this listing last changed Oct 8, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 51316-483-04 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
51316 labeler · 483 product · 04 package
Package marketed since
Feb 19, 2026
Sample package
No — commercial package
Listing certified through
Dec 31, 2027
Barcode (UPC-A, from the NDC)
3 5131648304 0
FDA record last changed
Oct 8, 2026

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 51316-483-04
Product NDC 51316-483
11-digit billing NDC 51316048304
Application # M017
SPL Set ID 4b333300-1ae7-a080-e063-6394a90a1372
Established class (EPC) Amide Local Anesthetic; Antiarrhythmic
Physiologic effect Local Anesthesia
Chemical class Amides
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2026-02-19
Route TOPICAL
Dosage form SPRAY
Substance MENTHOL, UNSPECIFIED FORM; LIDOCAINE
Why two NDCs? The FDA registers this code as 51316-483-04 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 51316-0483-04. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

Clinical

🧪 What is this product?

This is an over-the-counter topical spray containing lidocaine and menthol, marketed under FDA's OTC drug monograph rules. Lidocaine is a local anesthetic typically used to numb minor pain on the skin surface, while menthol is a cooling agent commonly used to produce a soothing sensation. Together, these ingredients are typically used in products designed for temporary relief of minor aches and pains.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer mLPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
51316-0483-04 You're viewing this Main listing 113 g in 1 CAN 2026-02-19 — Active

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Walgreens Cool n heat 4 g/100g; 1 g/100g 00363-3033-04 Walgreens 113 g — — FDA listed —
Icy Hot Lidocaine Dry 4 g/100mL; 1 g/100mL 41167-1740-02 Chattem, 113 ml — — FDA listed —
CVS Cold and Hot Pain Relief Dry 10 mg/g; 40 mg/gthis 51316-0483-04 CVS 113 g — — FDA listed —
HealthWise Max Lidocaine plus Menthol 4 g/100mL; 1 g/100mL 71101-0079-01 Veridian 113 ml — — FDA listed —
Picklebalm Lidocaine With Menthol Arnica Cucumber Seed 40 mg/mL; 10 mg/mL 71323-0203-00 Compass 118 ml — — FDA listed —
DCH Nerve Pain Relief 4 g/100g; 1 g/100g 72839-0223-05 Derma 142 g — — FDA listed —
Tidl Pain Relief Evening Therapy Spray. 1 g/100mL; 4 g/100mL 84214-0007-01 Shenzhen 90 ml — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2026
On the market since
Feb 2026
📍
2026
Currently FDA-listed
listed with the FDA
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 3K9958V90M
    A liquid solvent derived from fermentation or chemical synthesis. In medicines, alcohol dissolves active ingredients, helps preserve the product, and improves how the body absorbs certain drugs.
  • UNII C9H2L21V7U
    A fat derived from coconut or palm oil containing shorter fatty acid chains. It serves as a solvent and carrier to help dissolve or suspend active ingredients, improving absorption and stability in liquid formulations.
  • UNII 6DC9Q167V3
    Propylene glycol is a clear liquid derived from petroleum or vegetable sources. It acts as a solvent, humectant, and preservative in medicines, helping dissolve active ingredients and maintain product stability.

3 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesAlcohol Denat., Caprylic/Capric Triglyceride, Propylene Glycol

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerCVS Pharmacy
FDA applicationM017 (OTC MONOGRAPH DRUG)
Labeler code51316
First marketedFeb 2026
Product typeHuman Otc Drug
Portfolio551 products on file

More NDCs from CVS Pharmacy labeler code 51316

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Do Not Use 📄 When Using This Product 📄 Stop Use and Ask a Doctor If 🤰 If Pregnant or Breast-Feeding 📄 Keep Out of Reach of Children 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 5 words ▾

Use temporarily relieves minor pain

⏱️ Dosage and Administration 48 words ▾

Directions shake well adults and children 12 years of age and older: spray product on area not more than 1 to 3 times daily product will dry quickly on its own, and does not need to be rubbed in children under 12 years of age: ask a doctor

⚠️ Warnings 185 words ▾

Warnings For external use only Flammable: do not use while smoking or near heat or flame avoid long term storage above 104°F (40°C) do not sore at temperatures above 120 °F (49°C) Do not use on large areas of the body on cut, damaged, irritated or swollen skin more than one week without sonsulting a doctor When using this product use only as directed rare cases of serious burns have been reported with products of this type do not allow contact with eyes or mucous membranes avoid spraying on face avoid inhalation of spray do not bandage tightly do not use with a heating pad or other topical pain relief products contents under pressure do not puncture or incinerate.

Stop use and ask a doctor if condition worsens redness is present irritation develops symptoms persist for more than 7 days or clear up and occur again within a few days needed for longer than a week If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

🧪 Active Ingredient 6 words ▾

Active ingredients Lidocaine 4% Menthol 1%

🧪 Inactive Ingredients 8 words ▾

Inactive ingredients Alcohol Denatured, Caprylic/Capric Triglyceride, Propylene Glycol

🎯 Purpose 5 words ▾

Purposes Topical Analgesic Topical Analgesic

📄 Do Not Use 24 words ▾

Do not use on large areas of the body on cut, damaged, irritated or swollen skin more than one week without sonsulting a doctor

📄 When Using This Product 63 words ▾

When using this product use only as directed rare cases of serious burns have been reported with products of this type do not allow contact with eyes or mucous membranes avoid spraying on face avoid inhalation of spray do not bandage tightly do not use with a heating pad or other topical pain relief products contents under pressure do not puncture or incinerate.

📄 Stop Use and Ask a Doctor If 37 words ▾

Stop use and ask a doctor if condition worsens redness is present irritation develops symptoms persist for more than 7 days or clear up and occur again within a few days needed for longer than a week

🤰 If Pregnant or Breast-Feeding 10 words ▾

If pregnant or breast-feeding, ask a health professional before use.

📄 Keep Out of Reach of Children 19 words ▾

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

📄 Package Label / Principal Display Panel 64 words ▾

Principal Display Panel - 113 g Can CVS Health ® Compare to the active ingredients in IcyHot ® Lidociane Dry Spray* Maximum Strength Lidocaine concentration without a prescription † Lidocaine Pain Relief Dry Spray Plus Menthol Sprays at any angle Lidocaine 4% Menthol 1% Desensitizes aggravated nerves Dries instantly Fast & long-lasting relief NO-mess continuous spray NET WT 4 OZ (113 g) Can Label

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by CVS Pharmacy. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
CVS Pharmacy is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 51316-0477-40 · CVS 51316-0485-08 · CVS →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.