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Rabeprazole Sodium 20 mg Tablet, Delayed Release, 30-count — NDC 68180-220-06 (Billing 68180-0220-06)

by Lupin Pharmaceuticals, Inc. · 30 TABLET, DELAYED RELEASE in 1 BOTTLE

This is a package of 30 tablets of Rabeprazole Sodium 20 mg Tablet, Delayed Release from Lupin Pharmaceuticals, Inc., no longer marketed, no longer in the FDA NDC Directory; retail pharmacies pay about $0.2787 per tablet (NADAC). It is the main listing for this product, which comes in 2 package sizes.

NDC 68180-0220-06
🏷️ FDA NDC (as labeled) 68180-220-06 billing pads the product segment with a zero
This package
Contains30-count Cost per ea$0.2787 NADAC Per package$8.36 / 30 tablets Pack sizes2 compare ↓
Main listing for product 68180-220 · Also comes in: 90 tablets 68180-220-09
Rx only Generic Discontinued Non-controlled ⚠ Discontinued by firm ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Mar 13, 2024 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 68180-220-06 alone.

Record
FDA NDC Directory package listing · Human prescription drug
Code segments
68180 labeler · 220 product · 06 package
Billing quantity
30 EA per package
Barcode (UPC-A, from the NDC)
3 6818022006 0
FDA record last changed
Mar 13, 2024
⚠️
Excluded from the active FDA NDC Directory. The labeler reported this product as discontinued, so it is excluded from the active NDC Directory. The listing was last certified through Jun 2023. A label may still appear on DailyMed, but the NDC is no longer in the current FDA NDC Directory. Search the FDA NDC Directory ↗

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 68180-220-06
Product NDC 68180-220
11-digit billing NDC 68180022006
NCPDP billing unit EA — each (per item)
Application # ANDA078964
Mechanism of action Proton Pump Inhibitor [EPC], Proton Pump Inhibitors
DEA schedule Non-controlled
Marketing category ANDA
Marketing status Discontinued
FDA listing status Discontinued by firm (certified through Jun 2023)
Route ORAL
Dosage form TABLET, DELAYED RELEASE
Substance RABEPRAZOLE SODIUM
TE code (Orange Book) AB · RLD · RS

Drug-database identifiers Medi-Span GPI and First Databank GCN / HICL / AHFS classification

GCN Seq No 040941
GCN 94639
HICL code 018847
Ingredient (HICL) Rabeprazole Sodium
HIC1 code D
Therapeutic class — broad (HIC1) Biliary System/Gastro-Intestinal System
HIC2 code D4
Therapeutic class — intermediate (HIC2) Drugs Acting Principally On The Alimentary Tract
HIC3 code D4J
Therapeutic class — specific (HIC3) Proton-Pump Inhibitors
AHFS code 56:28.36.00
AHFS class Proton-Pump Inhibitors
FDB label name RABEPRAZOLE SOD DR 20 MG TAB
FDB brand name Rabeprazole Sodium
Legend status F — Federal legend — prescription drug or device
Quick answers
  • GSN (GCN sequence number): 040941
  • GCN: 94639
  • HICL (First Databank): 018847
  • AHFS class code: 56:28.36.00
Why two NDCs? The FDA registers this code as 68180-220-06 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 68180-0220-06. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

Clinical

Label name RABEPRAZOLE SOD DR 20 MG TAB Ingredient Rabeprazole Sodium
📖 What it is MedlinePlus · NLM

Rabeprazole is used to treat the symptoms of gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus (the tube that connects the throat and stomach) in adults and children 12 year of age and older. Rabeprazole is used to treat damage from GERD, allow the esophagus to heal, and prevent further damage to the esophagus in adults. Rabeprazole is also used to treat conditions in which the stomach produces too much acid, such as Zollinger-Ellison syndrome in adults. Rabeprazole is used to treat ulcers (...

Read the full MedlinePlus article ↗
📗 Our plain-language guide HelloPharmacist
  • It lowers stomach acid. Doctors use it for GERD, duodenal ulcers, H. pylori infection with duodenal ulcer disease, and conditions with too much stomach acid like Zollinger-Ellison...
  • Swallow the tablet whole. Don’t chew, crush or split it. For most uses, food doesn’t matter. For duodenal ulcers, take it after a meal. For H. pylori, take it with food, twice a da...
  • The AcipHex label says to take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Never take two doses together.
  • Most are mild, like pain, sore throat, gas or constipation. Teens may get headache, nausea or diarrhea. Call me or your doctor if you have severe or lasting diarrhea, a bad rash or...
📖 Read our full Rabeprazole guide →
9
Nutrient depletion considerations

Rabeprazole Sodium may be associated with lower levels of 9 nutrients — worth a chat with your pharmacist, not a cause for alarm.

🧪 Full Rabeprazole Sodium nutrient depletion report →
An association is not a deficiency. Educational only — don't start or stop anything without professional guidance.
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eaPer package
Retail pharmacies payNADAC · weekly $0.279 $8.36 / 30 tablets
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
NADAC price history (per ea) — tap or hover for the price & month
Dec 2021 Apr 2022 Sep 2022 Feb 2024 $0.279 $0.210
▲ Up 23% over the last 15 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Per unit Per pack Marketing startMarketing endStatus
68180-0220-06 You're viewing this Main listing 30 TABLET, DELAYED RELEASE in 1 BOTTLE $0.2787 / ea $8.36 2013-11-08 — Discontinued by firm
68180-0220-09 68180-220-09 90 TABLET, DELAYED RELEASE in 1 BOTTLE $0.2787 / ea $25.08 2013-11-08 — Discontinued by firm

You're viewing the smallest of 2 pack sizes for this product.

This pack has the lowest per-ea cost of the 2 priced pack sizes ($0.2787 NADAC).

Pack size FAQ

What quantity is in this package?
This is a 30-count package — 30 tablet, delayed release in 1 bottle.
How does this package differ from NDC 68180-0220-09?
Both are Rabeprazole Sodium 20 mg Tablet, Delayed Release — the drug itself is identical. This page's package is the 30-count one, while NDC 68180-0220-09 is the 90 tablets package.
What NDC number is used to bill for this package of Rabeprazole Sodium 20 mg Tablet, Delayed Release?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Prices are the latest CMS NADAC pharmacy acquisition cost per NDC; per-pack figures are per-unit × pack quantity, shown only when the pack is denominated in the same measure NADAC prices.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Rabeprazole Sodium 20 mg 62135-0503-30 Chartwell 30 tablets $0.224 AB Availability likely save 20%
Rabeprazole Sodium 20 mg 62175-0302-32 Lannett 30 tablets $0.224 AB Availability likely save 20%
Rabeprazole Sodium 20 mg 65862-0721-30 Aurobindo 30 tablets $0.224 — Availability likely save 20%
Rabeprazole Sodium 20 mg 67877-0443-30 Ascend 30 tablets $0.224 AB Availability likely save 20%
Rabeprazole Sodium 20 mg 72888-0059-30 Advagen 30 tablets $0.224 AB Availability likely save 20%
Rabeprazole sodium 20 mg 13668-0107-05 Torrent 500 tablets $0.279 AB FDA listed —
Rabeprazole Sodium 20 mgthis 68180-0220-06 Lupin 30 tablets $0.279 AB Discontinued —
Rabeprazole Sodium 20 mg 50090-4751-00 A-S 30 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 50090-6887-00 A-S 30 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 51407-0184-05 Golden 500 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 60760-0560-30 St. 30 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 60760-0972-30 St. 30 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 63187-0259-30 Proficient 30 tablets — AB FDA listed —
Rabeprazole sodium 20 mg 63187-0555-30 Proficient 30 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 65162-0724-03 Amneal 30 tablets — AB FDA listed —
Rabeprazole sodium 20 mg 68788-4060-03 Preferred 30 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 68788-7459-03 Preferred 30 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 68788-8536-03 Preferred 30 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 70518-2590-00 REMEDYREPACK 60 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 70518-3209-00 REMEDYREPACK 60 tablets — AB Discontinued —
Rabeprazole Sodium 20 mg 71205-0292-30 Proficient 30 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 71205-0603-30 Proficient 30 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 71335-0244-02 Bryant 90 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 71335-1100-02 Bryant 90 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 71335-1558-02 Bryant 90 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 71335-2304-02 Bryant 90 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 72162-2367-05 Bryant 500 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 72162-2503-03 Bryant 30 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 72189-0142-90 DIRECT 90 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 72189-0169-30 DIRECT 30 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 76420-0107-30 Asclemed 30 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 76420-0223-30 Asclemed 30 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 76420-0818-30 Asclemed 30 tablets — AB FDA listed —
Rabeprazole Sodium DR 20 mg 80425-0094-01 Advanced 30 tablets — AB FDA listed —
Rabeprazole Sodium DR 20 mg 80425-0134-01 Advanced 30 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 80425-0363-01 Advanced 30 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 80425-0449-01 Advanced 30 tablets — AB FDA listed —
Aciphex 20 mg 80725-0243-30 Waylis 30 tablets — AB FDA listed —
Rabeprazole Sodium 20 mg 85509-1443-03 PHOENIX 30 tablets — AB FDA listed —
About this product: this is a generic version of the medicine. FDA equivalence ratings are shown when available, and other versions are listed above, least expensive first.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

📍
2026
Currently FDA-listed
listed with the FDA
🔓
·
Generic on the market
this product is a generic
✅This is a generic drug

This product is an FDA-approved generic. Other versions of the same drug are listed under Therapeutic equivalents, least expensive first.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

We could not link this NDC to a current FDA Structured Product Label. An inactive-ingredient list is therefore not available from this source.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerLupin Pharmaceuticals, Inc.
Application holderCHARTWELL RX SCIENCES LLC
FDA applicationANDA078964 (ANDA)
Labeler code68180
Product typeHuman Prescription Drug
Portfolio404 products on file

More NDCs from Lupin Pharmaceuticals, Inc. labeler code 68180

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

Full prescribing information FDA SPL

The complete FDA label for this product — the official prescribing information, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
📄 FDA label
📄 FDA label 19 words ▾

No FDA label is on file for this product yet. Labels load from openFDA / DailyMed and refresh weekly.

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.

Medicare Part D spend CMS · PART D · 2026 (Q1)

Medicare Part D (outpatient prescription) spending for Rabeprazole Sodium — the program that covers self-administered drugs. 5 manufacturers.
⚠️ Drug-level data: CMS publishes Part D spending by drug, not by NDC — these figures combine every manufacturer, strength and package size sold under the name Rabeprazole Sodium. That’s a different level of aggregation than the Medicaid card above, which is specific to this exact 11-digit NDC (pack size included), so the two aren’t directly comparable.
Period
Total Part D spend
$3.14M
Claims incl. refills
88.3K
Beneficiaries
67.1K
Spend / beneficiary
$46.86
Spend / claim
$35.61
Trend by period
💵 About the dollar figures: spending is what Part D plans paid before confidential manufacturer rebates, so the program’s real net cost is lower. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part D Spending by Drug (data.cms.gov), updated quarterly.

About this NDC listing & data coverage

Finished prescription product No longer marketed (per FDA listing data)
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) — Not published for this NDC No structured label is linked to this listing in DailyMed/openFDA.
Package photos — Not published for this NDC The FDA label for this product carries no photos.
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) ✓ Available
Orange Book / therapeutic-equivalence data ✓ Available
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Why is there no full label on this page?
No structured FDA label (SPL) is currently linked to this NDC in DailyMed/openFDA. That can happen with older listings, certain OTC and repackaged products, and recently updated listings whose label has not yet propagated. The listing itself is still valid — this page shows everything the public feeds provide for this package.
What does the discontinued status mean for this NDC?
The labeler reported a marketing end date (or the listing was delisted), so this specific package is no longer actively marketed. Remaining stock may still be dispensed for a time, and the NDC stays valid for historical records and claims — but data feeds (pricing, labeling) typically stop updating for it. Other package sizes or other manufacturers' versions of the same medication may still be marketed — see the equivalents section where available.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Does this product come in other package sizes?
Yes — the FDA directory lists 1 other package presentation of this same product, including 90 tablets (68180-0220-09). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Lupin Pharmaceuticals, Inc. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as a prescription product, so it is dispensed under a prescriber's order. Your pharmacist can tell you whether any over-the-counter forms of the same medication exist.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 68180-0217-01 · Lupin 68180-0222-01 · Lupin →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.