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Oil-Free Daily Hydration SPF 15 OCTINOXATE, AVOBENZONE 50 mg/mL; 30 mg/mL Cream, 15 mL — NDC 76151-0105-52 package photo

Oil-Free Daily Hydration SPF 15 OCTINOXATE, AVOBENZONE 50 mg/mL; 30 mg/mL Cream, 15 mL

by Boscia LLC · 15 mL in 1 TUBE (76151-105-52)
NDC 76151-0105-52
🏷️ FDA NDC (as labeled) 76151-105-52 billing pads the product segment with a zero
This package
Contains15 mL Pack sizes2 compare ↓
Also comes in: 40 ml 76151-0105-11
OTC On market Non-controlled
🗂️ Data synced Aug 27, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 76151-105-52
Product NDC 76151-105
11-digit billing NDC 76151010552
UNII 4Y5P7MUD51, G63QQF2NOX
Application # M020
SPL Set ID ec322ae5-ab03-4c7b-9c6d-0bda3327c72a
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2011-04-16
Route TOPICAL
Dosage form CREAM
Substance OCTINOXATE; AVOBENZONE
Why two NDCs? The FDA registers this code as 76151-105-52 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 76151-0105-52. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏭 Manufacturer & labeler

LabelerBoscia LLC
FDA applicationM020 (OTC MONOGRAPH DRUG)
Labeler code76151
First marketedApr 2011
Product typeHuman Otc Drug
Portfolio11 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

🧪 What is this product?

This is an oil-free daily moisturizing cream applied to the skin that contains two sunscreen active ingredients: avobenzone and octinoxate. Both function as UV filters, typically used together to help protect skin from ultraviolet light damage. This product is marketed as an over-the-counter monograph drug, meaning it follows FDA's established rules for sunscreen products rather than being individually reviewed. The formulation is designed for daily facial hydration with built-in sun protection.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 5QB0T2IUN0
    Aluminum hydroxide is a white powder mineral compound used as an antacid ingredient in some formulations. It works as a buffer and pH regulator to help neutralize stomach acid in the medicine.
  • UNII 597E9BI3Z3
    Arctium lappa root is a plant-derived ingredient used in some traditional and herbal preparations. In formulations, it may serve as a natural extract or botanical agent to support product stability or flavor.
  • UNII 3XUS85K0RA
    Butylene glycol is a clear liquid derived from petroleum or plants that acts as a humectant, solvent, and preservative booster in medicines. It helps keep formulations stable, dissolve active ingredients, and maintain moisture in topical products.
  • UNII O730ZX2Z83
    A natural extract from bitter orange blossoms. Used as a flavoring agent and fragrance to improve taste and smell of the medicine.
  • UNII 08H094218D
    A plant extract from the flowering tops of narrow-leaf willowherb. It's used as a natural flavor and botanical ingredient to add taste and plant-derived components to the medicine.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • UNII 8136Y38GY5
    A plant-derived thickening agent made from cellulose. It increases the thickness and consistency of liquid medicines, helping them coat surfaces and flow smoothly.
  • UNII 50C1307PZG
    Pentylene glycol is a humectant and preservative helper derived from petroleum or plant sources. It draws moisture into the product and helps prevent bacterial growth, keeping medicines stable during storage.
  • UNII PBG27B754G
    Phellodendron amurense bark is a plant-derived ingredient from the cork tree. It functions as a natural preservative and antimicrobial agent to help maintain product stability and prevent microbial growth.
  • UNII B7862WZ632
    Potassium phosphate is a mineral salt that acts as a buffer and pH control agent in medicines. It helps keep the medication at the right acidity level for stability and proper absorption.
  • UNII IJ67X351P9
    A natural plant extract from rosemary leaves used as a preservative to help prevent oils and fats in the medicine from spoiling or becoming rancid during storage.
  • UNII ETJ7Z6XBU4
    Silicon dioxide is a naturally occurring mineral used as a glidant and anti-caking agent. It helps powder ingredients flow smoothly and prevents clumping during manufacturing and storage.
  • UNII 15FIX9V2JP
    Titanium dioxide is a bright white mineral powder commonly used as a colorant and opacifying agent. It makes pills and tablets white or lighter in color and helps make coatings non-transparent.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
  • UNII SOI2LOH54Z
    Zinc oxide is a white mineral powder used in medicines as a protective barrier agent and color additive. It helps shield skin in topical products and may also serve as a filler or opacifying ingredient.

15 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesInactive Ingredients: Water, Butylene Glycol, Silica, Glycerin, Polyglyceryl-10 Stearate, Pentylene Glycol, Simmondsia Chinensis (Jojoba) Leaf Extract, Epilobium Angustifolium Flower/leaf/stem Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Algae Extract, Hydrolyzed Yeast Extract, Arctium Lappa Root Extract, Phellodendron Amurense Bark Extract, Hydrogenated Rapeseed Alcohol, Hydroxyethylcellulose, Sclerotium Gum, Aluminum Hydroxide, Potassium Phosphate, Citrus Aurantium Amara (Bitter Orange) Flower Extract, Zinc Oxide, Titanium Dioxide.

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 40 ml
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Restorative Day Moisture SPF 15 50 mg/mL; 30 mg/mL 76151-0207-01 Boscia 30 ml — — FDA listed —
Oil-Free Daily Hydration SPF 15 50 mg/mL; 30 mg/mLthis 76151-0105-52 Boscia 15 ml — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2011
On the market since
Apr 2011
📍
2026
Currently FDA-listed
15 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

🔬 Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Oil-Free Daily Hydration SPF 15 (this brand).

Top reported reactions

Swelling Face1

Reporter sex

1 reports
Female · 100%
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
76151-0105-11 40 mL in 1 TUBE (76151-105-11) 2017-12-19 Active
76151-0105-52 You're viewing this 15 mL in 1 TUBE (76151-105-52) 2017-12-19 Active

You're viewing the smallest of 2 pack sizes for this product.

Pack size FAQ

What quantity is in NDC 76151-0105-52?
NDC 76151-0105-52 contains 15 mL — 15 ml in 1 tube.
What is the difference between NDC 76151-0105-52 and NDC 76151-0105-11?
Both are Oil-Free Daily Hydration SPF 15 OCTINOXATE, AVOBENZONE 50 mg/mL; 30 mg/mL Cream — the drug itself is identical. NDC 76151-0105-52 is the 15 mL package, while NDC 76151-0105-11 is the 40 ml package.
What NDC number is used to bill for this package of Oil-Free Daily Hydration SPF 15 OCTINOXATE, AVOBENZONE 50 mg/mL; 30 mg/mL Cream?
Bill NDC 76151-0105-52 — the 11-digit billing format is 76151010552. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 76151-105-52, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 76151-0105-52, written without dashes as 76151010552. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 76151-0105-52, the first segment (76151) is the labeler code FDA assigned to Boscia LLC; the middle segment (0105) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (52) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Boscia LLC. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 1 other package presentation of this same product, including 40 ml (76151-0105-11). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Boscia LLC is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📋 Description
🎯 Indications and Usage 4 words ▾

Use Helps prevent sunburn.

⏱️ Dosage and Administration 15 words ▾

Directions Apply small amount in AM to cleansed and toned face as last skincare step.

⚠️ Warnings 5 words ▾

Warnings For external use only.

🧪 Active Ingredient 9 words ▾

Active Ingredients Purpose Octinoxate 5% Sunscreen Avobenzone 3% Sunscreen

🧪 Inactive Ingredients 59 words ▾

Inactive Ingredients: Water, Butylene Glycol, Silica, Glycerin, Polyglyceryl-10 Stearate, Pentylene Glycol, Simmondsia Chinensis (Jojoba) Leaf Extract, Epilobium Angustifolium Flower/leaf/stem Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Algae Extract, Hydrolyzed Yeast Extract, Arctium Lappa Root Extract, Phellodendron Amurense Bark Extract, Hydrogenated Rapeseed Alcohol, Hydroxyethylcellulose, Sclerotium Gum, Aluminum Hydroxide, Potassium Phosphate, Citrus Aurantium Amara (Bitter Orange) Flower Extract, Zinc Oxide, Titanium Dioxide.

🎯 Purpose 4 words ▾

Use Helps prevent sunburn.

📋 Description 67 words ▾

Preservative-free. Dermatologist tested. Non-comedogenic.

Alcohol-free, pH balanced, 100% natural fragrance and color, no animals testing and no animal ingredients. An oil-free moisturizer that hydrates the skin, minimizes pores and providers broad spectrum SPF 15. Polysaccharide provides essential moisture, silica powder controls excessive oil while wine Yeast and Marine Complex help protect against external elements. www.boscia.net B105-11 Distributed by boscia LLC.

Irvine, CA 92614 Made in Japan U8-2

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 76147-0400-10 · StriVectin 76151-0106-12 · Boscia →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.