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J2599

J2599 – Injection, vasopressin (american regent) not therapeutically equivalent · NDC Crosswalk & Billing Units

HCPCS Level II J-code · Medicare Part B drug billing
J-code ● 3 NDCs crosswalked per 1 UNIT $0.834/unit ASP+6%

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

📋 J2599 summary

J2599 is a HCPCS Level II J-code used to bill vasopressin (american regent) not therapeutically equivalent to j2598, 1 unit, billed per 1 UNIT. The number of billing units to report depends on the dose administered and the NDC/package billed — use the calculator below.

Code J2599 Billing unit 1 UNIT Payment limit $0.834/unit NDC-Crosswalk 3 Quarter Q3 2026 RxCUI Atlas Trace the drug concept →

⚠ An NDC↔HCPCS crosswalk and a published payment limit do not guarantee payer coverage or payment. Always verify the current payer policy and claim format before billing.

🗂️ Key billing facts

HCPCS codeJ2599
DescriptorInjection, vasopressin (american regent) not therapeutically equivalent to j2598, 1 unit
Billing unit1 UNIT
Payment limit / unit$0.834
Est. ASP / unit$0.787 est.
Mapped NDCs3
Data periodQ3 2026
Last updated2026-08-20

💊 About Vasopressin DRUG GUIDE

Vasopressin injection is used in hospital settings to increase blood pressure in adults with vasodilatory shock — a life-threatening condition where blood vessels relax too much, causing blood pressure to drop severely.

This includes shock following heart surgery (post-cardiotomy shock) and shock caused by severe infection (septic shock).All available vasopressin injection products — including Vasostrict, Vasopressin in 0.9% Sodium Chloride, and Vasopressin Injection, USP — are indicated for this use in adults who remain dangerously hypotensive (low blood pressure) even after receiving IV fluids and catecholamines (other blood pressure–raising drugs).

Read the full Vasopressin drug guide →
Clinical overview from our editorial drug guide for Vasopressin. For billing reference, see the sections above.

🧾 Billing & reimbursement HCPCS · CMS · EFF. Q3 2026

📅 Payment limits effective Q3 2026 — from the CMS Medicare Part B Payment Limit File (revised quarterly).
Medicare payment limit / unit
$0.834
Est. ASP / unit
$0.787 est.
Est. after 2% sequester
$0.817
HCPCS dosage
1 UNIT
The CMS payment limit is the Medicare Part B drug allowance (ASP + 6%, statutory). After the 2% federal sequester the effective payment is ≈ ASP + 4.3%; estimated ASP = payment limit ÷ 1.06. Source: CMS Medicare Part B Payment Limit File (quarterly), Q3 2026.
Full HCPCS code details (official CMS record)
Long descriptionInjection, vasopressin (american regent) not therapeutically equivalent to j2598, 1 unit
CoverageC — Carrier/MAC judgment
Pricing indicator51 — Drug — priced under the ASP methodology
Type of service1 — Medical care
BETOS-2O1E
ASC payment groupYY
Action codeP — Payment change
Effective date2024-01-01
Date added2023-07-01
Source: CMS HCPCS Level II code file (imported via admin).

🧮 Dosing & billing-units calculator HCPCS UNITS

One billing unit of J2599 = 1 unit. Enter a regimen to convert dose → billing units and project a full course.
Billing units = dose ÷ HCPCS unit size. Most payers require whole units — round per the payer's policy. “Est. Medicare pay” uses the current payment limit. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (JZ when none is discarded) where allowed. Always verify payer-specific rounding before billing.

🔁 NDCs that bill under J2599 WITH EST. MEDICARE PAY

3 NDCs map to J2599. Bill units = how many HCPCS units one package represents. Est. pay / pkg = payment limit ($0.834/unit) × that package's bill units.
NDC (11-digit)DrugLabelerPackageStrength Bill units Est. pay / pkg NADAC / unit StatusSource
00517-1020-25 Vasopressin 20 [USP'U]/mL INJECTION, SOLUTION American 25 VIAL, SINGLE-DOSE in 1 CARTON (0517-102... 20 [USP'U]/mL 500 $417.00 — ● Active CMS + PDAC
00517-1030-01 Vasopressin 20 [USP'U]/mL INJECTION, SOLUTION American 1 VIAL, MULTI-DOSE in 1 CARTON (0517-1030-... 20 [USP'U]/mL 200 $166.80 — ● Active CMS + PDAC
72572-0860-25 Vasopressin 20 [USP'U]/mL INJECTION, SOLUTION Civica, 25 VIAL, SINGLE-DOSE in 1 CARTON (72572-86... 20 [USP'U]/mL 500 $417.00 — ● Active CMS + PDAC
NDC→HCPCS mappings come from the CMS ASP NDC-HCPCS crosswalk; additional DME MAC / DMEPOS mappings come from PDAC and are labeled separately. NADAC from CMS (weekly). “Status” reflects the product's marketing / obsolete flag in the NDC directory. Presence or absence here does not determine Medicare coverage. Linked NDCs open the full product page.

📈 Medicare Part B claims detail CMS PSPS · 2024

Calendar-year 2024 Medicare Part B fee-for-service activity for this HCPCS code, summed across all carriers, localities and specialties (CMS Physician/Supplier Procedure Summary). A “service” is one billed line/unit — not one claim — so counts run higher than claim counts.
Allowed charges
$0.00
Medicare paid
$0.00
Submitted services
31
Denial rate
100.0%
Submitted charges
$296.73
Source: CMS Physician/Supplier Procedure Summary (PSPS), CY2024 — Medicare Part B carrier + DME fee-for-service claims (excludes Medicare Advantage). Figures are for the whole HCPCS code, which may cover uses beyond this drug. ⚠ CMS hides any figure covering fewer than 11 patients (a privacy rule), so totals — especially denials and low-volume codes — run a little low.

🗺️ Where J2599 is utilized

⏳
The geographic utilization map is building for this code — it aggregates millions of CMS Part B claim lines, then caches the result. Refresh in a moment; if it doesn’t appear, this code may have no reportable Part B utilization.

📊 What bills under J2599

J-codes are billing codes often used for drugs billed under the medical benefit. This connects the billing code to the NDC package records it covers, by ingredient and labeler.

NDC products by ingredient
Vasopressin 3
NDC products by labeler
American Regent, Inc. 2
Civica, Inc. 1

🗃️ Data sources & freshness

Every figure on this page is computed from public datasets. Here's what each section draws on and how current it is.
HCPCS code & descriptor
CMS HCPCS Level II code file
Loaded
Payment limit & billing unit
CMS Medicare Part B ASP Pricing File (quarterly)
Q3 2026 · as of 2026-08-20
NDC ↔ HCPCS crosswalk
CMS ASP NDC-HCPCS crosswalk + DMEPDAC (PDAC)
3 NDCs mapped
NADAC acquisition cost
CMS National Average Drug Acquisition Cost (weekly)
Not available for mapped NDCs
Utilization & spend
CMS Part B Spending by Drug · PSPS · Physician & Other Practitioners
No reportable utilization
Figures are estimates for reference and may lag the source files. Always verify against the current CMS files and your payer's policy before submitting claims.

⚠️ Practical billing caveats

  • A crosswalk is not coverage. An NDC mapping or a published payment limit does not guarantee a payer will cover or pay this code. Check the specific plan's policy.
  • Units ≠ milligrams. Bill the number of HCPCS units (dose ÷ the code's unit size), not the milligram dose. Use the calculator above.
  • Discarded drug. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (and JZ when nothing is discarded) where the payer allows.
  • Rounding & partial units. Many payers require whole units; round per the payer's policy, not automatically up.
  • The code can cover more than this drug. Some HCPCS codes span multiple products or strengths — confirm the exact code for the product administered.
  • Figures lag. ASP limits change quarterly and utilization data are released with a delay. Verify against the current CMS files before billing.

❓ J2599 billing FAQ

What is HCPCS code J2599?
J2599 is a HCPCS Level II J-code used to bill Injection, vasopressin (american regent) not therapeutically equivalent to j2598, 1 unit under Medicare Part B and most medical (not pharmacy) benefits.
What is the billing unit for J2599?
One unit of J2599 represents 1 UNIT. Report the number of units equal to the dose administered divided by 1 UNIT.
How many units of J2599 should I bill?
Divide the dose administered by the code's unit size (1 UNIT) to get the number of billing units, then round per your payer's policy. The calculator on this page converts a dose into billing units and projects a full course.
How much does Medicare pay for J2599?
The Medicare Part B payment limit is $0.834 per unit (Q3 2026), based on ASP + 6%. After the 2% sequester the effective payment is about $0.817 per unit. Payment limits are revised quarterly.
Which NDCs bill under J2599?
3 NDCs currently map to J2599 in the CMS ASP NDC-HCPCS crosswalk. See the NDC crosswalk table above for each product, package, billing units and estimated reimbursement.
Does a crosswalk mean J2599 is covered?
No. An NDC-to-HCPCS crosswalk and a published payment limit do not guarantee coverage or payment. Coverage depends on the payer, the diagnosis and the site of care — always verify the current policy before billing.
For professional billing reference only — verify against the current CMS files before submitting claims.