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J3246

J3246 – Injection, tirofiban hcl, 0.25 mg · NDC Crosswalk & Billing Units

HCPCS Level II J-code · Medicare Part B drug billing
J-code ● 12 NDCs crosswalked per 0.25 MG $2.917/unit ASP+6%

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

📋 J3246 summary

J3246 is a HCPCS Level II J-code used to bill tirofiban hcl, 0.25 mg, billed per 0.25 MG. The number of billing units to report depends on the dose administered and the NDC/package billed — use the calculator below.

Brand names associated with J3246: Tirofiban Hydrochloride, Aggrastat, Tirofiban

Code J3246 Billing unit 0.25 MG Payment limit $2.917/unit NDC-Crosswalk 12 Quarter Q3 2026 RxCUI Atlas Trace the drug concept →

⚠ An NDC↔HCPCS crosswalk and a published payment limit do not guarantee payer coverage or payment. Always verify the current payer policy and claim format before billing.

🗂️ Key billing facts

HCPCS codeJ3246
DescriptorInjection, tirofiban hcl, 0.25 mg
Billing unit0.25 MG
Payment limit / unit$2.917
Est. ASP / unit$2.752 est.
Mapped NDCs12
Data periodQ3 2026
Last updated2026-09-20

💊 About Tirofiban DRUG GUIDE

Tirofiban is used to reduce the rate of thrombotic cardiovascular events in people with non-ST elevation acute coronary syndrome (NSTE-ACS).

That means a combined outcome of death, heart attack (myocardial infarction), or ongoing heart blood-flow problems that need another cardiac procedure.The same use applies to Aggrastat and to the tirofiban hydrochloride injection products.

Read the full Tirofiban drug guide →
Clinical overview from our editorial drug guide for Tirofiban. For billing reference, see the sections above.

🧾 Billing & reimbursement HCPCS · CMS · EFF. Q3 2026

📅 Payment limits effective Q3 2026 — from the CMS Medicare Part B Payment Limit File (revised quarterly).
Medicare payment limit / unit
$2.917
Est. ASP / unit
$2.752 est.
Est. after 2% sequester
$2.859
HCPCS dosage
0.25 MG
The CMS payment limit is the Medicare Part B drug allowance (ASP + 6%, statutory). After the 2% federal sequester the effective payment is ≈ ASP + 4.3%; estimated ASP = payment limit ÷ 1.06. Source: CMS Medicare Part B Payment Limit File (quarterly), Q3 2026.
Full HCPCS code details (official CMS record)
Long descriptionInjection, tirofiban hcl, 0.25 mg
CoverageC — Carrier/MAC judgment
Pricing indicator51 — Drug — priced under the ASP methodology
Type of service1 — Medical care
BETOS-2O1E
ASC payment groupYY
Action codeP — Payment change
Effective date2024-01-01
Date added2005-01-01
Source: CMS HCPCS Level II code file (imported via admin).

🧮 Dosing & billing-units calculator HCPCS UNITS

One billing unit of J3246 = 0.25 mg. Enter a regimen to convert dose → billing units and project a full course.
Billing units = dose ÷ HCPCS unit size. Most payers require whole units — round per the payer's policy. “Est. Medicare pay” uses the current payment limit. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (JZ when none is discarded) where allowed. Always verify payer-specific rounding before billing.

🔁 NDCs that bill under J3246 WITH EST. MEDICARE PAY

12 NDCs map to J3246. Bill units = how many HCPCS units one package represents. Est. pay / pkg = payment limit ($2.917/unit) × that package's bill units.
NDC (11-digit)DrugLabelerPackageStrength Bill units Est. pay / pkg NADAC / unit StatusSource
14789-0102-05 Tirofiban Nexus — — 50 $145.85 — — CMS ASP
14789-0102-10 Tirofiban Hydrochloride 50 ug/mL INJECTION Nexus 2 BAG in 1 CARTON (14789-102-10) / 250 mL... 50 ug/mL 100 $291.70 — ● Active CMS ASP
25021-0417-84 Tirofiban Hydrochloride 50 ug/mL INJECTION, SOLUTION Sagent 1 BAG in 1 CARTON (25021-417-84) / 250 mL... 50 ug/mL 50 $145.85 — ● Active CMS ASP
25208-0001-04 AGGRASTAT TIROFIBAN 3.75 mg/15mL INJECTION, SOLUTION Medicure 1 VIAL, GLASS in 1 CARTON (25208-001-04)... 3.75 mg/15mL 15 $43.76 — ● Active CMS + PDAC
25208-0002-01 AGGRASTAT TIROFIBAN 5 mg/100mL INJECTION, SOLUTION Medicure 1 BAG in 1 CARTON (25208-002-01) / 100 mL... 5 mg/100mL 20 $58.34 — ● Active CMS + PDAC
25208-0002-02 AGGRASTAT TIROFIBAN 5 mg/100mL INJECTION, SOLUTION Medicure 1 CONTAINER in 1 CARTON (25208-002-02) /... 5 mg/100mL 50 $145.85 — ● Active CMS + PDAC
25208-0002-03 Aggrastat Medicure — — 20 $58.34 — — CMS + PDAC
25208-0901-04 AGGRASTAT TIROFIBAN 3.75 mg/15mL INJECTION, SOLUTION Medicure 1 VIAL, GLASS in 1 CARTON (25208-901-04)... 3.75 mg/15mL 15 $43.76 — ● Active CMS ASP
25208-0902-01 AGGRASTAT TIROFIBAN 5 mg/100mL INJECTION, SOLUTION Medicure 1 BAG in 1 CARTON (25208-902-01) / 100 mL... 5 mg/100mL 20 $58.34 — ● Active CMS ASP
25208-0902-02 AGGRASTAT TIROFIBAN 5 mg/100mL INJECTION, SOLUTION Medicure 1 CONTAINER in 1 CARTON (25208-902-02) /... 5 mg/100mL 50 $145.85 — ● Active CMS ASP
55150-0429-01 Tirofiban 5 mg/100mL INJECTION, SOLUTION Eugia 1 POUCH in 1 CARTON (55150-429-01) / 1 BA... 5 mg/100mL 20 $58.34 — ● Active CMS ASP
55150-0430-01 Tirofiban 12.5 mg/250mL INJECTION, SOLUTION Eugia 1 POUCH in 1 CARTON (55150-430-01) / 1 BA... 12.5 mg/250mL 50 $145.85 — ● Active CMS ASP
NDC→HCPCS mappings come from the CMS ASP NDC-HCPCS crosswalk; additional DME MAC / DMEPOS mappings come from PDAC and are labeled separately. NADAC from CMS (weekly). “Status” reflects the product's marketing / obsolete flag in the NDC directory. Presence or absence here does not determine Medicare coverage. Linked NDCs open the full product page.

🗺️ Where J3246 is utilized

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The geographic utilization map is building for this code — it aggregates millions of CMS Part B claim lines, then caches the result. Refresh in a moment; if it doesn’t appear, this code may have no reportable Part B utilization.

📊 What bills under J3246

J-codes are billing codes often used for drugs billed under the medical benefit. This connects the billing code to the NDC package records it covers, by ingredient and labeler.

NDC products by ingredient
TIROFIBAN 2
NDC products by labeler
Medicure International Inc 2

🗃️ Data sources & freshness

Every figure on this page is computed from public datasets. Here's what each section draws on and how current it is.
HCPCS code & descriptor
CMS HCPCS Level II code file
Loaded
Payment limit & billing unit
CMS Medicare Part B ASP Pricing File (quarterly)
Q3 2026 · as of 2026-09-20
NDC ↔ HCPCS crosswalk
CMS ASP NDC-HCPCS crosswalk + DMEPDAC (PDAC)
12 NDCs mapped
NADAC acquisition cost
CMS National Average Drug Acquisition Cost (weekly)
Not available for mapped NDCs
Utilization & spend
CMS Part B Spending by Drug · PSPS · Physician & Other Practitioners
No reportable utilization
Figures are estimates for reference and may lag the source files. Always verify against the current CMS files and your payer's policy before submitting claims.

⚠️ Practical billing caveats

  • A crosswalk is not coverage. An NDC mapping or a published payment limit does not guarantee a payer will cover or pay this code. Check the specific plan's policy.
  • Units ≠ milligrams. Bill the number of HCPCS units (dose ÷ the code's unit size), not the milligram dose. Use the calculator above.
  • Discarded drug. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (and JZ when nothing is discarded) where the payer allows.
  • Rounding & partial units. Many payers require whole units; round per the payer's policy, not automatically up.
  • The code can cover more than this drug. Some HCPCS codes span multiple products or strengths — confirm the exact code for the product administered.
  • Figures lag. ASP limits change quarterly and utilization data are released with a delay. Verify against the current CMS files before billing.

❓ J3246 billing FAQ

What is HCPCS code J3246?
J3246 is a HCPCS Level II J-code used to bill Injection, tirofiban hcl, 0.25 mg under Medicare Part B and most medical (not pharmacy) benefits.
What is the billing unit for J3246?
One unit of J3246 represents 0.25 MG. Report the number of units equal to the dose administered divided by 0.25 MG.
How many units of J3246 should I bill?
Divide the dose administered by the code's unit size (0.25 MG) to get the number of billing units, then round per your payer's policy. The calculator on this page converts a dose into billing units and projects a full course.
How much does Medicare pay for J3246?
The Medicare Part B payment limit is $2.917 per unit (Q3 2026), based on ASP + 6%. After the 2% sequester the effective payment is about $2.859 per unit. Payment limits are revised quarterly.
Which NDCs bill under J3246?
12 NDCs currently map to J3246 in the CMS ASP NDC-HCPCS crosswalk. See the NDC crosswalk table above for each product, package, billing units and estimated reimbursement.
Does a crosswalk mean J3246 is covered?
No. An NDC-to-HCPCS crosswalk and a published payment limit do not guarantee coverage or payment. Coverage depends on the payer, the diagnosis and the site of care — always verify the current policy before billing.
For professional billing reference only — verify against the current CMS files before submitting claims.