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J3291

J3291 – INJECTION, TRANEXAMIC ACID IN SODIUM CHLORIDE, 5 MG · NDC Crosswalk & Billing Units

HCPCS Level II J-code · Medicare Part B drug billing
J-code ● 5 NDCs crosswalked

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

📋 J3291 summary

J3291 is a HCPCS Level II J-code used to bill TRANEXAMIC ACID IN SODIUM CHLORIDE, 5 MG. The number of billing units to report depends on the dose administered and the NDC/package billed — use the calculator below.

Brand names associated with J3291: Tranexamic Acid

Code J3291 NDC-Crosswalk 5 RxCUI Atlas Trace the drug concept →

⚠ An NDC↔HCPCS crosswalk and a published payment limit do not guarantee payer coverage or payment. Always verify the current payer policy and claim format before billing.

🗂️ Key billing facts

HCPCS codeJ3291
DescriptorINJECTION, TRANEXAMIC ACID IN SODIUM CHLORIDE, 5 MG
Billing unitNot available in current dataset
Payment limit / unit Not available in current dataset
Mapped NDCs5
Data periodNot available in current dataset
Last updatedSource date not available

💊 About Tranexamic Acid DRUG GUIDE

Tranexamic acid injection — including the brands Cyklokapron and Tranexamic Acid in Sodium Chloride — is used in people with hemophilia to reduce or prevent bleeding and to lower the need for clotting-factor replacement therapy around the time of a tooth extraction.

This use is short-term (2 to 8 days).Tranexamic acid tablets (brand Lysteda, and generic tranexamic acid tablets) are used to treat cyclic heavy menstrual bleeding in females of reproductive age.

They are taken only during each menstrual period, not every day of the month.

Read the full Tranexamic Acid drug guide →
Clinical overview from our editorial drug guide for Tranexamic Acid. For billing reference, see the sections above.

🧾 Billing & reimbursement HCPCS · CMS

Medicare payment limit / unit
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Est. ASP / unit
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Est. after 2% sequester
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HCPCS dosage
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The CMS payment limit is the Medicare Part B drug allowance (ASP + 6%, statutory). After the 2% federal sequester the effective payment is ≈ ASP + 4.3%; estimated ASP = payment limit ÷ 1.06. Source: CMS Medicare Part B Payment Limit File (quarterly).

🧮 Dosing & billing-units calculator HCPCS UNITS

One billing unit of J3291 = 1 unit. Enter a regimen to convert dose → billing units and project a full course.
Billing units = dose ÷ HCPCS unit size. Most payers require whole units — round per the payer's policy. “Est. Medicare pay” uses the current payment limit. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (JZ when none is discarded) where allowed. Always verify payer-specific rounding before billing.

🔁 NDCs that bill under J3291 CROSSWALKED NDCs

5 NDCs map to J3291. Bill units = how many HCPCS units one package represents.
NDC (11-digit)DrugLabelerPackageStrength Bill units NADAC / unit StatusSource
14789-0115-05 Tranexamic Acid 10 mg/mL INJECTION, SOLUTION Nexus 10 BAG in 1 CARTON (14789-115-05) / 100 m... 10 mg/mL 2 — ● Active PDAC
25021-0418-82 Tranexamic Acid 10 mg/mL INJECTION, SOLUTION Sagent 10 BAG in 1 CARTON (25021-418-82) / 100 m... 10 mg/mL 2 — ● Active PDAC
65219-0534-10 TRANEXAMIC ACID IN SODIUM CHLORIDE 10 mg/mL INJECTION, SOLUTION Fresenius 24 BAG in 1 CASE (65219-534-10) / 100 mL... 10 mg/mL 2 — ● Active PDAC
80830-2329-02 TRANEXAMIC ACID IN SODIUM CHLORIDE 10 mg/mL INJECTION, SOLUTION Amneal 10 POUCH in 1 CARTON (80830-2329-2) / 1 B... 10 mg/mL 2 — ● Active PDAC
80830-2329-03 TRANEXAMIC ACID IN SODIUM CHLORIDE 10 mg/mL INJECTION, SOLUTION Amneal 12 POUCH in 1 CARTON (80830-2329-3) / 1 B... 10 mg/mL 2 — ● Active PDAC
NDC→HCPCS mappings come from the CMS ASP NDC-HCPCS crosswalk; additional DME MAC / DMEPOS mappings come from PDAC and are labeled separately. NADAC from CMS (weekly). “Status” reflects the product's marketing / obsolete flag in the NDC directory. Presence or absence here does not determine Medicare coverage. Linked NDCs open the full product page.

🗺️ Where J3291 is utilized

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The geographic utilization map is building for this code — it aggregates millions of CMS Part B claim lines, then caches the result. Refresh in a moment; if it doesn’t appear, this code may have no reportable Part B utilization.

📊 What bills under J3291

J-codes are billing codes often used for drugs billed under the medical benefit. This connects the billing code to the NDC package records it covers, by ingredient and labeler.

NDC products by ingredient
tranexamic acid 3
Tranexamic Acid 2
NDC products by labeler
Amneal Pharmaceuticals Private Lim... 2
Nexus Pharmaceuticals LLC 1
Sagent Pharmaceuticals 1
Fresenius Kabi USA, LLC 1

🗃️ Data sources & freshness

Every figure on this page is computed from public datasets. Here's what each section draws on and how current it is.
HCPCS code & descriptor
CMS HCPCS Level II code file
Not available in current dataset
Payment limit & billing unit
CMS Medicare Part B ASP Pricing File (quarterly)
Not available
NDC ↔ HCPCS crosswalk
CMS ASP NDC-HCPCS crosswalk + DMEPDAC (PDAC)
5 NDCs mapped
NADAC acquisition cost
CMS National Average Drug Acquisition Cost (weekly)
Not available for mapped NDCs
Utilization & spend
CMS Part B Spending by Drug · PSPS · Physician & Other Practitioners
No reportable utilization
Figures are estimates for reference and may lag the source files. Always verify against the current CMS files and your payer's policy before submitting claims.

⚠️ Practical billing caveats

  • A crosswalk is not coverage. An NDC mapping or a published payment limit does not guarantee a payer will cover or pay this code. Check the specific plan's policy.
  • Units ≠ milligrams. Bill the number of HCPCS units (dose ÷ the code's unit size), not the milligram dose. Use the calculator above.
  • Discarded drug. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (and JZ when nothing is discarded) where the payer allows.
  • Rounding & partial units. Many payers require whole units; round per the payer's policy, not automatically up.
  • The code can cover more than this drug. Some HCPCS codes span multiple products or strengths — confirm the exact code for the product administered.
  • Figures lag. ASP limits change quarterly and utilization data are released with a delay. Verify against the current CMS files before billing.

❓ J3291 billing FAQ

What is HCPCS code J3291?
J3291 is a HCPCS Level II J-code used to bill INJECTION, TRANEXAMIC ACID IN SODIUM CHLORIDE, 5 MG under Medicare Part B and most medical (not pharmacy) benefits.
Which NDCs bill under J3291?
5 NDCs currently map to J3291 in the CMS ASP NDC-HCPCS crosswalk. See the NDC crosswalk table above for each product, package, billing units and estimated reimbursement.
Does a crosswalk mean J3291 is covered?
No. An NDC-to-HCPCS crosswalk and a published payment limit do not guarantee coverage or payment. Coverage depends on the payer, the diagnosis and the site of care — always verify the current policy before billing.
For professional billing reference only — verify against the current CMS files before submitting claims.