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{28 (estrogens, conjugated (USP) 0.625 MG / medroxyprogesterone acetate 2.5 MG Oral Tablet... — RxCUI 1000499

RxNorm drug concept · Brand name pack
RxCUI 1000499 Brand name pack · BPCK ● Current RxNorm concept 5 FDA products 5 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1000499
Official name{28 (estrogens, conjugated (USP) 0.625 MG / medroxyprogesterone acetate 2.5 MG Oral Tablet) } Pack [Prempro 0.625/2.5 28 Day]
Concept typeBrand name pack (BPCK)
RxNorm statusCurrent RxNorm concept
Also known asPrempro 0.625/2.5 28 Day Pack
FDA products mapped5
Package NDCs mapped5
Reported Medicaid activity (SDUD)48,214 prescriptions · 46 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Medroxyprogesterone Injection: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • It's mainly used as birth control — one shot provides contraceptive protection for about 3 months. If you're using Depo-SubQ Provera 104 specifically, it also has a second approved...
  • What exactly is this injection used for?
  • Honestly, irregular bleeding is one of the most common things people notice — especially in the first few months. You might have spotting, lighter periods, heavier periods, or unpr...
  • What will happen to my period on this injection?
📖 Read our full Medroxyprogesterone Injection guide →

🕸️ Concept Web — How {28 (estrogens, conjugated (USP) 0.625 MG / medr... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept {28 (estrogens, conjugated (USP) 0.625 MG / medroxyprogesterone acetate 2.5 MG Oral Tablet) } Pack [Prempro 0.625/2.5 28 Day] RxCUI 1000499

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 4

    The active substance itself — no strength, form, or brand attached yet.

    • Estrogens, conjugated (USP) 4099
    • Medroxyprogesterone 6691
    • Estrogens, conjugated (USP) / medroxyprogesterone 1006917
    • Medroxyprogesterone acetate 1000112
  2. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Estrogens, conjugated (USP) / medroxyprogesterone Oral Tablet 378788
    • Estrogens, conjugated (USP) / medroxyprogesterone acetate Oral Tablet 2645566
    • Estrogens, conjugated (USP) / medroxyprogesterone Oral Product 1165781
    • Estrogens, conjugated (USP) / medroxyprogesterone Pill 1165782
    • Estrogens, conjugated (USP) / medroxyprogesterone acetate Oral Product 2661462
    • Estrogens, conjugated (USP) / medroxyprogesterone acetate Pill 2662429
    • Pack 746839
    • Oral Product 1151131
    • +1 more in this family
  3. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

  4. Packs 1

    Fixed collections of drugs packaged and sold together, like dose packs.

Showing up to 8 concepts per family — 16 of 17 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

📦 FDA Products & Package NDCs

5 products · 5 package NDCs
5 package NDCs map to RxCUI 1000499 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00046-1105-11 1 BLISTER PACK in 1 CARTON (0046-1105-11) / 28 TABLET, SUGA... Prempro Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc. 2009-09-21
00046-1106-11 1 BLISTER PACK in 1 CARTON (0046-1106-11) / 28 TABLET, SUGA... Prempro Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc. 2009-09-21
00046-1107-11 1 BLISTER PACK in 1 CARTON (0046-1107-11) / 28 TABLET, SUGA... Prempro Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc. 2009-09-21
00046-1108-11 1 BLISTER PACK in 1 CARTON (0046-1108-11) / 28 TABLET, SUGA... Prempro Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc. 2012-12-03
00046-2575-12 1 BLISTER PACK in 1 CARTON (0046-2575-12) / 1 KIT in 1 BLIS... Premphase Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc. 2012-03-01
Observed labelers: Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc. (5) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.