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Acetaminophen 20 MG/ML / hydrocodone bitartrate 0.667 MG/ML Oral Solution — RxCUI 1044427

Name: Acetaminophen 20 MG/ML / hydrocodone bitartrate 0.667 MG/ML Oral Solution (RxCUI 1044427)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 1044427 Semantic clinical drug · SCD ● Current RxNorm concept 2 FDA products 2 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1044427

Official nameAcetaminophen 20 MG/ML / hydrocodone bitartrate 0.667 MG/ML Oral Solution

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known asAPAP 20 MG/ML / Hydrocodone Bitartrate 0.667 MG/ML Oral Solution; HYDROcodone bitartrate 10 MG / acetaminophen 300 MG in 15 mL Oral Solution; APAP 300 MG / hydrocodone bitartrate 10 MG per 15 ML Oral Solution

FDA products mapped2

Package NDCs mapped2

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Acetaminophen Injection: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

It treats mild to moderate pain, and moderate to severe pain when used with opioid medicines. It also lowers fever. It is given through a vein in a healthcare setting.
What is Acetaminophen Injection used for?
It is given as an IV infusion over 15 minutes by a healthcare professional. Your dose depends on your age and weight. Your care team follows the label and your prescriber's orders.
The most common are nausea and vomiting. Adults may also get headache or trouble sleeping. Children may have constipation or itching.

📖 Read our full Acetaminophen Injection guide →

🕸️ Concept Web — How Acetaminophen 20 MG/ML / hydrocodone bitartrate... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Acetaminophen 20 MG/ML / hydrocodone bitartrate 0.667 MG/ML Oral Solution RxCUI 1044427 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 4

The active substance itself — no strength, form, or brand attached yet.
- Acetaminophen 161 IN
- Hydrocodone 5489 IN
- Acetaminophen / hydrocodone 214182 MIN
- Hydrocodone bitartrate 142439 PIN
Dose forms 9

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Acetaminophen / hydrocodone Oral Solution 370759 SCDF
- Acetaminophen / hydrocodone bitartrate Oral Solution 2646966 SCDFP
- Acetaminophen / hydrocodone Oral Liquid Product 1151548 SCDG
- Acetaminophen / hydrocodone Oral Product 1151549 SCDG
- Acetaminophen / hydrocodone bitartrate Oral Liquid Product 2663318 SCDGP
- Acetaminophen / hydrocodone bitartrate Oral Product 2661100 SCDGP
- Oral Solution 316968 DF
- Oral Liquid Product 1151137 DFG
- +1 more in this family
Clinical & branded drugs 2

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Acetaminophen 20 MG/ML 330880 SCDC
- Hydrocodone bitartrate 0.667 MG/ML 857124 SCDC

Showing up to 8 concepts per family — 14 of 15 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Acetaminophen 20 MG/ML SCDC · 330880
Hydrocodone bitartrate 0.667 MG/ML SCDC · 857124
Acetaminophen / hydrocodone Oral Solution SCDF · 370759
Acetaminophen / hydrocodone bitartrate Oral Solution SCDFP · 2646966
Acetaminophen / hydrocodone Oral Liquid Product SCDG · 1151548
Acetaminophen / hydrocodone Oral Product SCDG · 1151549
Acetaminophen / hydrocodone bitartrate Oral Liquid Product SCDGP · 2663318
Acetaminophen / hydrocodone bitartrate Oral Product SCDGP · 2661100

📦 FDA Products & Package NDCs

2 products · 2 package NDCs

2 package NDCs map to RxCUI 1044427 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
00054-0843-63	473 mL in 1 BOTTLE (0054-0843-63)	HYDROCODONE BITARTRATE AND ACETAMINOPHEN	Hikma Pharmaceuticals USA Inc.	2025-06-16
27808-0130-01	473 mL in 1 BOTTLE, PLASTIC (27808-130-01)	hydrocodone bitartrate and acetaminophen	Cranbury Pharmaceuticals, LLC	2022-12-30

Observed labelers: Cranbury Pharmaceuticals, LLC (1) · Hikma Pharmaceuticals USA Inc. (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.