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1 ML diphenhydramine hydrochloride 50 MG/ML Prefilled Syringe — RxCUI 1049289

Name: 1 ML diphenhydramine hydrochloride 50 MG/ML Prefilled Syringe (RxCUI 1049289)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 1049289 Semantic clinical drug · SCD ● Current RxNorm concept 2 FDA products 2 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1049289

Official name1 ML diphenhydramine hydrochloride 50 MG/ML Prefilled Syringe

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known asdiphenhydramine HCl 50 MG per 1 ML Prefilled Syringe; diphenhydrAMINE HCl 50 MG in 1 ML Prefilled Syringe

FDA products mapped2

Package NDCs mapped2

Reported Medicaid activity (SDUD)3,479 prescriptions · 23 state & territory Medicaid programs · latest period Q4 2025

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Diphenhydramine Topical: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

You can use it for temporary relief of pain and itching from everyday skin problems — things like insect bites, minor burns, minor cuts and scrapes, and general skin irritations. I...
What can I actually use this cream or spray for?
You can apply it up to 3 to 4 times a day, but no more than that. More frequent use isn't going to help more — and the label is clear that you shouldn't exceed that limit. For kids...
This is really important — do not use this topical product at the same time as any other product that contains diphenhydramine, even a pill or capsule. That includes allergy medici...

📖 Read our full Diphenhydramine Topical guide →

🕸️ Concept Web — How 1 ML diphenhydramine hydrochloride 50 MG/ML Pref... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept 1 ML diphenhydramine hydrochloride 50 MG/ML Prefilled Syringe RxCUI 1049289 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 2

The active substance itself — no strength, form, or brand attached yet.
- Diphenhydramine 3498 IN
- Diphenhydramine hydrochloride 1362 PIN
Dose forms 6

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Diphenhydramine Prefilled Syringe 727526 SCDF
- Diphenhydramine hydrochloride Prefilled Syringe 2647386 SCDFP
- Diphenhydramine Injectable Product 1158446 SCDG
- Diphenhydramine hydrochloride Injectable Product 2660161 SCDGP
- Prefilled Syringe 721656 DF
- Injectable Product 1151126 DFG
Clinical & branded drugs 1

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Diphenhydramine hydrochloride 50 MG/ML 1049288 SCDC

Showing up to 8 concepts per family — 9 of 9 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Diphenhydramine hydrochloride 50 MG/ML SCDC · 1049288
Diphenhydramine Prefilled Syringe SCDF · 727526
Diphenhydramine hydrochloride Prefilled Syringe SCDFP · 2647386
Diphenhydramine Injectable Product SCDG · 1158446
Diphenhydramine hydrochloride Injectable Product SCDGP · 2660161

📦 FDA Products & Package NDCs

2 products · 2 package NDCs

2 package NDCs map to RxCUI 1049289 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
76045-0102-10	24 BLISTER PACK in 1 CARTON (76045-102-10) / 1 SYRINGE, GLA...	Diphenhydramine Hydrochloride	Fresenius Kabi USA, LLC	2013-03-26
76045-0235-10	24 BLISTER PACK in 1 CARTON (76045-235-10) / 1 SYRINGE, GLA...	Diphenhydramine Hydrochloride	Fresenius Kabi USA, LLC	2025-06-02

Observed labelers: Fresenius Kabi USA, LLC (2) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🧾 Billing Codes (HCPCS)

Medical billing codes (HCPCS "J-codes") that connect to this concept's packages — used mostly when a clinic or hospital bills for a drug it administers. Each code links to its full billing page.

Code	Descriptor	Mapped packages	Sources
J1200	Diphenhydramine hcl injectio	1	CMS

⚠ A crosswalk is not coverage: an NDC↔HCPCS mapping does not guarantee any payer covers or pays the code. Always verify the current payer policy before billing.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.