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Drospirenone 3 MG / ethinyl estradiol 0.03 MG / levomefolate calcium 0.451 MG Oral Tablet — RxCUI 1050492

Name: Drospirenone 3 MG / ethinyl estradiol 0.03 MG / levomefolate calcium 0.451 MG Oral Ta… (RxCUI 1050492)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 1050492 Semantic clinical drug · SCD ● Current RxNorm concept 3 FDA products 6 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1050492

Official nameDrospirenone 3 MG / ethinyl estradiol 0.03 MG / levomefolate calcium 0.451 MG Oral Tablet

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

FDA products mapped3

Package NDCs mapped6

Reported Medicaid activity (SDUD)486 prescriptions · 7 state & territory Medicaid programs · latest period Q4 2025

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Drospirenone / Ethinyl Estradiol / Levomefolate: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

It's primarily a birth control pill, but it does a few things at once. The hormone combination stops ovulation to prevent pregnancy. It also includes a form of folate (a B vitamin)...
What is this pill actually doing — is it just birth control?
The first one to three packs are the most likely time to notice nausea, spotting between periods, breast tenderness, or headaches. These usually settle down on their own — don't st...
What side effects should I expect when I first start taking it?

📖 Read our full Drospirenone / Ethinyl Estradiol / Levomefolate guide →

🕸️ Concept Web — How Drospirenone 3 MG / ethinyl estradiol 0.03 MG /... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Drospirenone 3 MG / ethinyl estradiol 0.03 MG / levomefolate calcium 0.451 MG Oral Tablet RxCUI 1050492 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 5

The active substance itself — no strength, form, or brand attached yet.
- Drospirenone 11636 IN
- Ethinyl estradiol 4124 IN
- Levomefolate 1592257 IN
- Drospirenone / ethinyl estradiol / levomefolate 1013625 MIN
- Levomefolate calcium 1028454 PIN
Dose forms 9

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Drospirenone / ethinyl estradiol / levomefolate Oral Tablet 1013624 SCDF
- Drospirenone / ethinyl estradiol / levomefolate calcium Oral Tablet 2646163 SCDFP
- Drospirenone / ethinyl estradiol / levomefolate Oral Product 1861727 SCDG
- Drospirenone / ethinyl estradiol / levomefolate Pill 1861726 SCDG
- Drospirenone / ethinyl estradiol / levomefolate calcium Oral Product 2660791 SCDGP
- Drospirenone / ethinyl estradiol / levomefolate calcium Pill 2662820 SCDGP
- Oral Tablet 317541 DF
- Oral Product 1151131 DFG
- +1 more in this family
Clinical & branded drugs 3

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Drospirenone 3 MG 343266 SCDC
- Ethinyl estradiol 0.03 MG 315897 SCDC
- Levomefolate calcium 0.451 MG 1013623 SCDC
Packs 3

Fixed collections of drugs packaged and sold together, like dose packs.

Showing up to 8 concepts per family — 19 of 20 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

{21 (drospirenone 3 MG / ethinyl estradiol 0.03 MG / levomefolate calcium 0.451 MG Oral Tablet) / 7 (levomefolate calcium 0.451 MG Oral Tablet) } Pack GPCK · 1050493
Drospirenone 3 MG SCDC · 343266
Ethinyl estradiol 0.03 MG SCDC · 315897
Levomefolate calcium 0.451 MG SCDC · 1013623
Drospirenone / ethinyl estradiol / levomefolate Oral Tablet SCDF · 1013624
Drospirenone / ethinyl estradiol / levomefolate calcium Oral Tablet SCDFP · 2646163
Drospirenone / ethinyl estradiol / levomefolate Oral Product SCDG · 1861727
Drospirenone / ethinyl estradiol / levomefolate Pill SCDG · 1861726
Drospirenone / ethinyl estradiol / levomefolate calcium Oral Product SCDGP · 2660791
Drospirenone / ethinyl estradiol / levomefolate calcium Pill SCDGP · 2662820

Brand-Name Concepts

📦 FDA Products & Package NDCs

3 products · 6 package NDCs

6 package NDCs map to RxCUI 1050492 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
00781-4103-15	3 BLISTER PACK in 1 PACKAGE (0781-4103-15) / 1 KIT in 1 BLI...	Drospirenone/ethinyl estradiol/levomefolate calcium and levomefolate calcium	Sandoz Inc	2015-08-01
50419-0403-00	90 BLISTER PACK in 1 PACKAGE (50419-403-00) / 1 KIT in 1 BL...	Safyral	Bayer HealthCare Pharmaceuticals Inc.	2012-02-13
50419-0403-03	3 BLISTER PACK in 1 PACKAGE (50419-403-03) / 1 KIT in 1 BLI...	Safyral	Bayer HealthCare Pharmaceuticals Inc.	2012-02-13
50419-0403-70	90 BLISTER PACK in 1 PACKAGE (50419-403-70) / 1 KIT in 1 BL...	Safyral	Bayer HealthCare Pharmaceuticals Inc.	2012-02-13
50419-0403-75	12 PACKAGE in 1 CARTON (50419-403-75) / 5 BLISTER PACK in 1...	Safyral	Bayer HealthCare Pharmaceuticals Inc.	2012-02-13
68180-0904-73	3 POUCH in 1 CARTON (68180-904-73) / 1 BLISTER PACK in 1 PO...	Tydemy	Lupin Pharmaceuticals, Inc.	2020-11-20

Observed labelers: Bayer HealthCare Pharmaceuticals Inc. (4) · Lupin Pharmaceuticals, Inc. (1) · Sandoz Inc (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.