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Diphenhydramine hydrochloride 50 MG Oral Tablet — RxCUI 1085945

RxNorm drug concept · Semantic clinical drug
RxCUI 1085945 Semantic clinical drug · SCD ● Current RxNorm concept 12 FDA products 14 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1085945
Official nameDiphenhydramine hydrochloride 50 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asdiphenhydrAMINE HCl 50 MG Oral Tablet
FDA products mapped12
Package NDCs mapped14
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Diphenhydramine Topical: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • It gives temporary relief of pain and itching on the skin. That includes minor burns, minor cuts or scrapes, insect bites, minor skin irritations, and rashes from poison ivy, oak o...
  • Adults and children 2 and older can apply it to the affected area no more than 3 to 4 times a day. Don't use it more often than directed. For a child under 2, check with a doctor f...
  • No. Don't use it on large areas of the body or on broken, blistered or oozing skin. Also avoid it on chicken pox or sunburn.
  • Can I put it on a large area or on blistered skin?
📖 Read our full Diphenhydramine Topical guide →

🕸️ Concept Web — How Diphenhydramine hydrochloride 50 MG Oral Tablet Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Diphenhydramine hydrochloride 50 MG Oral Tablet RxCUI 1085945

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 2

    The active substance itself — no strength, form, or brand attached yet.

    • Diphenhydramine 3498
    • Diphenhydramine hydrochloride 1362
  2. Brand names 5

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Benadryl 203457
    • Compoz 1085965
    • Sominex 152371
    • Somnapure 1609065
    • Twilite 220559
  3. Dose forms 29

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Diphenhydramine Oral Tablet 371892
    • Diphenhydramine hydrochloride Oral Tablet 2649122
    • Diphenhydramine Oral Product 1158449
    • Diphenhydramine Pill 1158450
    • Diphenhydramine hydrochloride Oral Product 2659104
    • Diphenhydramine hydrochloride Pill 2659100
    • Diphenhydramine Oral Tablet [Benadryl] 369212
    • Diphenhydramine Oral Tablet [Compoz] 1085967
    • +21 more in this family
  4. Clinical & branded drugs 11

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 23 of 47 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Diphenhydramine hydrochloride 50 MG SCDC · 1020476
  • Diphenhydramine Oral Tablet SCDF · 371892
  • Diphenhydramine hydrochloride Oral Tablet SCDFP · 2649122
  • Diphenhydramine Oral Product SCDG · 1158449
  • Diphenhydramine Pill SCDG · 1158450
  • Diphenhydramine hydrochloride Oral Product SCDGP · 2659104
  • Diphenhydramine hydrochloride Pill SCDGP · 2659100

Brand-Name Concepts

📦 FDA Products & Package NDCs

12 products · 14 package NDCs
14 package NDCs map to RxCUI 1085945 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00363-1799-08 2 BLISTER PACK in 1 CARTON (0363-1799-08) / 12 TABLET, FILM... Allergy Relief Walgreen Company 2025-06-02
15579-0828-17 1 BOTTLE in 1 BOX (15579-828-17) / 100 TABLET in 1 BOTTLE Jet-Asleep Double Strength Night Time Sleep Aid Bell Pharmaceuticals, Inc. 2017-10-07
15579-0828-23 3 BLISTER PACK in 1 BOX (15579-828-23) / 8 TABLET in 1 BLIS... Jet-Asleep Double Strength Night Time Sleep Aid Bell Pharmaceuticals, Inc. 2017-10-07
17714-0023-50 50 TABLET in 1 BOTTLE (17714-023-50) Diphenhydramine Hydrochloride Advance Pharmaceutical Inc. 2012-09-01
37835-0852-50 50 TABLET in 1 BOTTLE (37835-852-50) Diphenhydramine HCl Maximum Strength Bi-Mart 2025-05-01
46122-0829-51 2 BLISTER PACK in 1 CARTON (46122-829-51) / 12 TABLET in 1... Allergy Relief AMERISOURCE BERGEN 2026-05-04
50580-0533-24 2 BLISTER PACK in 1 CARTON (50580-533-24) / 12 TABLET, FILM... Benadryl Allergy EXTRA STRENGTH Kenvue Brands LLC 2022-07-05
51316-0221-08 2 BLISTER PACK in 1 CARTON (51316-221-08) / 12 TABLET, COAT... Diphenhydramine HCl CVS Pharmacy, Inc. 2024-01-31
51316-0799-08 2 BLISTER PACK in 1 CARTON (51316-799-08) / 12 TABLET, FILM... Allergy Relief Extra Strength CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED 2026-01-27
55910-0450-12 2 BLISTER PACK in 1 CARTON (55910-450-12) / 12 TABLET in 1... Allergy Relief DOLGENCORP INC 2025-06-24
63029-0505-16 1 BLISTER PACK in 1 BOX (63029-505-16) / 16 TABLET in 1 BLI... Sominex Max Medtech Products Inc. 2012-06-01
69452-0445-24 1 BOTTLE in 1 CARTON (69452-445-24) / 150 TABLET in 1 BOTTL... Allergy Relief BIONPHARMA INC. 2025-08-11
69452-0445-77 4 BLISTER PACK in 1 CARTON (69452-445-77) / 12 TABLET in 1... Allergy Relief BIONPHARMA INC. 2025-08-11
69721-0005-30 1 BOTTLE in 1 CARTON (69721-005-30) / 30 TABLET, COATED in... Somnapure Clinical Strength Force Factor Brands LLC 2018-03-20
Observed labelers: Bell Pharmaceuticals, Inc. (2) · BIONPHARMA INC. (2) · Advance Pharmaceutical Inc. (1) · AMERISOURCE BERGEN (1) · Bi-Mart (1) · CVS Pharmacy, Inc. (1) · +6 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.