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Naproxen sodium 220 MG Oral Capsule [Aleve] — RxCUI 1112233

RxNorm drug concept · Semantic branded drug
RxCUI 1112233 Semantic branded drug · SBD ● Current RxNorm concept 3 FDA products 14 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1112233
Official nameNaproxen sodium 220 MG Oral Capsule [Aleve]
Concept typeSemantic branded drug (SBD)
RxNorm statusCurrent RxNorm concept
Also known asAleve 220 MG Oral Capsule; Aleve 220 MG (naproxen 200 MG) Oral Capsule
FDA products mapped3
Package NDCs mapped14
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Naproxen: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • It relieves pain, inflammation and fever. Prescription versions treat arthritis, tendonitis, bursitis, acute gout and painful periods. Over-the-counter versions handle minor aches...
  • Take it by mouth with a full glass of water. Over-the-counter products are taken every 8 to 12 hours while symptoms last, and you should use the smallest dose that works. For presc...
  • Headache, indigestion, heartburn, nausea and swelling are common. Call your doctor if you have black stools, vomit blood, a rash, yellow skin or eyes, or chest pain.
  • Usually not. Combining naproxen with other NSAIDs or aspirin raises bleeding risk with little added benefit. Naproxen can also interfere with low-dose aspirin taken for your heart,...
📖 Read our full Naproxen guide →

🕸️ Concept Web — How Naproxen sodium 220 MG Oral Capsule [Aleve] Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Naproxen sodium 220 MG Oral Capsule [Aleve] RxCUI 1112233

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 2

    The active substance itself — no strength, form, or brand attached yet.

    • Naproxen 7258
    • Naproxen sodium 142442
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Aleve 215101
  3. Dose forms 13

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Naproxen Oral Capsule 373002
    • Naproxen sodium Oral Capsule 2648502
    • Naproxen Oral Product 1157517
    • Naproxen Pill 1157518
    • Naproxen sodium Oral Product 2659458
    • Naproxen sodium Pill 2661667
    • Naproxen Oral Capsule [Aleve] 1112232
    • Naproxen sodium Oral Capsule [Aleve] 2654714
    • +5 more in this family
  4. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 14 of 19 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Naproxen sodium 220 MG Oral Capsule SCD · 1112231
  • Naproxen sodium 220 MG SCDC · 849573
  • Naproxen Oral Capsule SCDF · 373002
  • Naproxen sodium Oral Capsule SCDFP · 2648502
  • Naproxen Oral Product SCDG · 1157517
  • Naproxen Pill SCDG · 1157518
  • Naproxen sodium Oral Product SCDGP · 2659458
  • Naproxen sodium Pill SCDGP · 2661667

Brand-Name Concepts

  • Naproxen sodium 220 MG [Aleve] SBDC · 849727
  • Naproxen Oral Capsule [Aleve] SBDF · 1112232
  • Naproxen sodium Oral Capsule [Aleve] SBDFP · 2654714
  • Aleve Oral Product SBDG · 1175502
  • Aleve Pill SBDG · 1175503
  • Aleve BN · 215101

📦 FDA Products & Package NDCs

3 products · 14 package NDCs
14 package NDCs map to RxCUI 1112233 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00280-0105-01 120 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0280-0105-0... Aleve liquid gels Bayer Healthcare LLC 2024-06-28
00280-0105-02 160 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0280-0105-0... Aleve liquid gels Bayer Healthcare LLC 2023-12-01
00280-0105-03 20 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0280-0105-03... Aleve liquid gels Bayer Healthcare LLC 2024-05-07
00280-0105-04 50 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0280-0105-04... Aleve liquid gels Bayer Healthcare LLC 2024-05-14
00280-0105-05 80 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0280-0105-05... Aleve liquid gels Bayer Healthcare LLC 2024-05-21
00280-0105-06 80 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0280-0105-06... Aleve liquid gels Bayer Healthcare LLC 2024-06-17
00280-6080-01 1 BOTTLE in 1 CARTON (0280-6080-01) / 120 CAPSULE, LIQUID F... Aleve Bayer HealthCare LLC. 2007-02-20
00280-6080-02 2 BOTTLE in 1 PACKAGE, COMBINATION (0280-6080-02) / 80 CAPS... Aleve Bayer HealthCare LLC. 2007-02-20
00280-6080-04 1 BOTTLE, PLASTIC in 1 CARTON (0280-6080-04) / 50 CAPSULE,... Aleve Bayer HealthCare LLC. 2022-10-20
00280-6080-16 160 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0280-6080-1... Aleve Bayer HealthCare LLC. 2007-02-20
00280-6080-20 1 BOTTLE, PLASTIC in 1 CARTON (0280-6080-20) / 20 CAPSULE,... Aleve Bayer HealthCare LLC. 2007-02-20
00280-6080-40 1 BOTTLE, PLASTIC in 1 CARTON (0280-6080-40) / 40 CAPSULE,... Aleve Bayer HealthCare LLC. 2007-02-20
00280-6080-80 1 BOTTLE, PLASTIC in 1 CARTON (0280-6080-80) / 80 CAPSULE,... Aleve Bayer HealthCare LLC. 2007-02-20
00280-6091-80 1 BOTTLE, PLASTIC in 1 CARTON (0280-6091-80) / 80 CAPSULE,... Aleve Easy Open Arthritis Cap Bayer HealthCare LLC. 2007-07-28
Observed labelers: Bayer HealthCare LLC. (8) · Bayer Healthcare LLC (6) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.