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Dextromethorphan hydrobromide 4 MG/ML / guaifenesin 80 MG/ML Oral Solution — RxCUI 1113368

Name: Dextromethorphan hydrobromide 4 MG/ML / guaifenesin 80 MG/ML Oral Solution (RxCUI 1113368)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 1113368 Semantic clinical drug · SCD ● Current RxNorm concept 3 FDA products 5 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1113368

Official nameDextromethorphan hydrobromide 4 MG/ML / guaifenesin 80 MG/ML Oral Solution

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known asdextromethorphan hydrobromide 4 MG/ML / guaifenesin 80 MG/ML Syrup; dextromethorphan HBr 20 MG / guaiFENesin 400 MG in 5 mL Oral Solution; dextromethorphan hydrobromide 20 MG / guaifenesin 400 MG per 5 ML Oral Solution

FDA products mapped3

Package NDCs mapped5

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Dextromethorphan: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

It won't necessarily silence your cough entirely, but it does temporarily suppress the cough reflex and reduce how intense and frequent your cough is. It can also help reduce that...
What exactly does dextromethorphan do — will it stop my cough completely?
It depends on your child's age and the specific product. Most dextromethorphan products should not be given to children under 4 years old without a doctor's guidance. Some products...
This is a really important question. If your antidepressant is an MAOI (monoamine oxidase inhibitor), you absolutely cannot take dextromethorphan — not while you're on it, and not...

📖 Read our full Dextromethorphan guide →

🕸️ Concept Web — How Dextromethorphan hydrobromide 4 MG/ML / guaifene... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Dextromethorphan hydrobromide 4 MG/ML / guaifenesin 80 MG/ML Oral Solution RxCUI 1113368 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 4

The active substance itself — no strength, form, or brand attached yet.
- Dextromethorphan 3289 IN
- Guaifenesin 5032 IN
- Dextromethorphan / guaifenesin 214488 MIN
- Dextromethorphan hydrobromide 102490 PIN
Dose forms 9

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Dextromethorphan / guaifenesin Oral Solution 371766 SCDF
- Dextromethorphan hydrobromide / guaifenesin Oral Solution 2647597 SCDFP
- Dextromethorphan / guaifenesin Oral Liquid Product 1155190 SCDG
- Dextromethorphan / guaifenesin Oral Product 1155191 SCDG
- Dextromethorphan hydrobromide / guaifenesin Oral Liquid Product 2660140 SCDGP
- Dextromethorphan hydrobromide / guaifenesin Oral Product 2663099 SCDGP
- Oral Solution 316968 DF
- Oral Liquid Product 1151137 DFG
- +1 more in this family
Clinical & branded drugs 2

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Dextromethorphan hydrobromide 4 MG/ML 1010978 SCDC
- Guaifenesin 80 MG/ML 331795 SCDC

Showing up to 8 concepts per family — 14 of 15 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Dextromethorphan hydrobromide 4 MG/ML SCDC · 1010978
Guaifenesin 80 MG/ML SCDC · 331795
Dextromethorphan / guaifenesin Oral Solution SCDF · 371766
Dextromethorphan hydrobromide / guaifenesin Oral Solution SCDFP · 2647597
Dextromethorphan / guaifenesin Oral Liquid Product SCDG · 1155190
Dextromethorphan / guaifenesin Oral Product SCDG · 1155191
Dextromethorphan hydrobromide / guaifenesin Oral Liquid Product SCDGP · 2660140
Dextromethorphan hydrobromide / guaifenesin Oral Product SCDGP · 2663099

📦 FDA Products & Package NDCs

3 products · 5 package NDCs

5 package NDCs map to RxCUI 1113368 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
45737-0251-16	473 mL in 1 BOTTLE (45737-251-16)	Bio-Z-Cough	Advanced Generic Corporation	2012-07-01
52083-0400-01	30 mL in 1 BOTTLE, PLASTIC (52083-400-01)	ZYNCOF	Kramer Novis	2011-06-01
52083-0400-04	120 mL in 1 BOTTLE, PLASTIC (52083-400-04)	ZYNCOF	Kramer Novis	2011-06-01
52083-0400-16	474 mL in 1 BOTTLE, PLASTIC (52083-400-16)	ZYNCOF	Kramer Novis	2013-01-23
52083-0600-16	473 mL in 1 BOTTLE, PLASTIC (52083-600-16)	G-ZYNCOF	Kramer Novis	2012-12-03

Observed labelers: Kramer Novis (4) · Advanced Generic Corporation (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.