Dextromethorphan

Generic name: Pronounced as (dex troe meth or' fan)
Brand names
  • Delsym 12-hour Cough
  • Robitussin Cough Long-Acting®
  • Triaminic Long-Acting Cough®
  • Vicks DayQuil Cough®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 07/15/2021

Dextromethorphan is used to temporarily relieve cough caused by the common cold, the flu, or other conditions. Dextromethorphan will relieve a cough but will not treat the cause of the cough or speed recovery. Dextromethorphan is in a class of medications called antitussives. It works by decreasing activity in the part of the brain that causes coughing.

Dextromethorphan comes as a liquid-filled capsule, a chewable tablet, a dissolving strip, a solution (liquid), an extended-release (long-acting) suspension (liquid), and a lozenge to take by mouth. It is usually taken every 4 to 12 hours as needed. Follow the directions on the package or prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

Dextromethorphan should only be used according to the label or package directions. Do not take more than the recommended amount of dextromethorphan in a 24-hour period. Refer to the package or prescription label to determine the amount contained in each dose. Taking dextromethorphan in large amounts can cause serious side effects or death.

Dextromethorphan comes alone and in combination with antihistamines, cough suppressants, and decongestants. Ask your doctor or pharmacist for advice on which product is best for your symptoms. Check nonprescription cough and cold product labels carefully before using 2 or more products at the same time. These products may contain the same active ingredient(s) and taking them together could cause you to receive an overdose. This is especially important if you will be giving cough and cold medications to a child.

Nonprescription cough and cold combination products, including products that contain dextromethorphan, can cause serious side effects or death in young children. Do not give these products to children younger than 4 years of age. If you give these products to children 4-11 years of age, use caution and follow the package directions carefully.

If you are giving dextromethorphan or a combination product that contains dextromethorphan to a child, read the package label carefully to be sure that it is the right product for a child of that age. Do not give dextromethorphan products that are made for adults to children.

Before you give a dextromethorphan product to a child, check the package label to find out how much medication the child should receive. Give the dose that matches the child's age on the chart. Ask the child's doctor if you don't know how much medication to give the child.

If you are taking the liquid, do not use a household spoon to measure your dose. Use the measuring spoon or cup that came with the medication or use a spoon made especially for measuring medication.

If you are using the dissolving strips, place them on your tongue and swallow after they melt.

If you are taking the chewable tablets you can allow them to melt in your mouth or you can chew them before swallowing.

If you are taking the extended-release suspension, shake the bottle well before each use to mix the medication evenly.

If you are taking the lozenges, allow them to slowly melt in your mouth.

Stop taking dextromethorphan and call your doctor if your cough does not get better within 7 days, if your cough goes away and comes back, or if your cough occurs with a fever, rash, or headache.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking dextromethorphan,

  • tell your doctor and pharmacist if you are allergic to dextromethorphan, any other medications, or any of the ingredients in the product you plan to take. Check the package label for a list of the ingredients.

  • do not take dextromethorphan if you are taking a monoamine oxidase (MAO) inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate), or if you have stopped taking an MAO inhibitor within the past 2 weeks.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.

  • tell your doctor if you smoke, if you have a cough that occurs with a large amount of phlegm (mucus), or if you have or have ever had breathing problems such as asthma, emphysema, or chronic bronchitis.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking dextromethorphan, call your doctor.

  • if you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent mental retardation), you should know that some brands of chewable tablets that contain dextromethorphan may be sweetened with aspartame, a source of phenylalanine.

Unless your doctor tells you otherwise, continue your normal diet.

Dextromethorphan is usually taken as needed. If your doctor has told you to take dextromethorphan regularly, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Dextromethorphan may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • dizziness

    • lightheadedness

    • drowsiness

    • nervousness

    • restlessness

    • nausea

    • vomiting

    • stomach pain

  • If you experience any of the following symptoms, call your doctor immediately:

    • rash

  • Dextromethorphan may cause other side effects. Call your doctor if you experience any unusual problems while you are taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include:

  • nausea

  • vomiting

  • drowsiness

  • dizziness

  • unsteadiness

  • changes in vision

  • difficulty breathing

  • fast heartbeat

  • hallucinating (seeing things or hearing voices that do not exist)

  • seizures

  • coma (loss of consciousness for a period of time)

Ask your pharmacist any questions you have about dextromethorphan.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

  • Alka-Seltzer Plus Cold and Cough Formula® (containing Aspirin, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Alka-Seltzer Plus Day and Night Cold Formulas® (containing Aspirin, Dextromethorphan, Phenylephrine)
  • Alka-Seltzer Plus Day Non-Drowsy Cold Formula® (containing Acetaminophen, Dextromethorphan, Phenylephrine)
  • Alka-Seltzer Plus Flu Formula® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Alka-Seltzer Plus Mucus and Congestion® (containing Dextromethorphan, Guaifenesin)
  • Alka-Seltzer Plus Night Cold Formula® (containing Aspirin, Dextromethorphan, Doxylamine, Phenylephrine)
  • Children's Dimetapp Cold and Cough® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • Children's Dimetapp Multisymptom Cold and Flu® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Children's Mucinex Cough® (containing Dextromethorphan, Guaifenesin)
  • Children's Mucinex Multi-Symptom Cold® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Children's Robitussin Cough and Cold CF® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Children's Robitussin Cough and Cold Long-Acting® (containing Chlorpheniramine, Dextromethorphan)
  • Children's Sudafed PE Cold and Cough® (containing Dextromethorphan, Phenylephrine)
  • Coricidin HBP Chest Congestion and Cough® (containing Dextromethorphan, Guaifenesin)
  • Coricidin HBP Cough and Cold® (containing Chlorpheniramine, Dextromethorphan)
  • Coricidin HBP Day and Night Multi-Symptom Cold® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Guaifenesin)
  • Coricidin HBP Maximum Strength Flu® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan)
  • Coricidin HBP Nighttime Multi-Symptom Cold® (containing Acetaminophen, Dextromethorphan, Doxylamine)
  • Diabetic Tussin DM® (containing Dextromethorphan, Guaifenesin)
  • Dimetane DX® (containing Brompheniramine, Dextromethorphan, Pseudoephedrine)
  • Mucinex Cough for Kids® (containing Dextromethorphan, Guaifenesin)
  • Mucinex DM® (containing Dextromethorphan, Guaifenesin)
  • PediaCare Children's Cough and Congestion® (containing Dextromethorphan, Guaifenesin)
  • PediaCare Children's Fever Reducer Plus Cough and Runny Nose® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan)
  • PediaCare Children's Fever Reducer Plus Cough and Sore Throat® (containing Acetaminophen, Dextromethorphan)
  • PediaCare Children's Fever Reducer Plus Flu® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • PediaCare Children's Fever Reducer Plus Multi-Symptom Cold® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Robitussin Cough and Chest DM® (containing Dextromethorphan, Guaifenesin)
  • Robitussin Cough and Cold CF® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Robitussin Cough and Cold Long-Acting® (containing Chlorpheniramine, Dextromethorphan)
  • Robitussin Night Time Cough, Cold, and Flu® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Sudafed PE Cold/Cough® (containing Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine)
  • Sudafed PE Day/Night Cold® (containing Acetaminophen, Dextromethorphan, Diphenhydramine, Guaifenesin, Phenylephrine)
  • Theraflu Cold and Cough® (containing Dextromethorphan, Pheniramine, Phenylephrine)
  • Theraflu Daytime Severe Cold and Cough® (containing Acetaminophen, Dextromethorphan, Phenylephrine)
  • Theraflu Max-D Severe Cold and Flu® (containing Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine)
  • Triaminic Cough and Sore Throat® (containing Acetaminophen, Dextromethorphan)
  • Triaminic Day Time Cold and Cough® (containing Dextromethorphan, Phenylephrine)
  • Triaminic Multi-Symptom Fever® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan)
  • Tussin DM® (containing Dextromethorphan, Guaifenesin)
  • Tylenol Cold and Cough Daytime® (containing Acetaminophen, Dextromethorphan)
  • Tylenol Cold and Cough Nighttime® (containing Acetaminophen, Dextromethorphan, Doxylamine)
  • Tylenol Cold and Flu Severe® (containing Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine)
  • Tylenol Cold and Mucus Severe® (containing Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine)
  • Tylenol Cold Multi-Symptom Nighttime® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Vicks Children's NyQuil Cold and Cough® (containing Chlorpheniramine, Dextromethorphan)
  • Vicks DayQuil Cold and Flu Relief® (containing Acetaminophen, Dextromethorphan, Phenylephrine)
  • Vicks DayQuil Cold and Flu Symptom Relief Plus Vitamin C® (containing Acetaminophen, Dextromethorphan, Phenylephrine)
  • Vicks DayQuil Mucus Control DM® (containing Dextromethorphan, Guaifenesin)

Drug Interaction
Montelukast Montelukast The metabolism of Dextromethorphan can be decreased when combined with Montelukast.
Leflunomide Leflunomide The metabolism of Dextromethorphan can be decreased when combined with Leflunomide.
Delavirdine Delavirdine The metabolism of Dextromethorphan can be decreased when combined with Delavirdine.
Nevirapine Nevirapine The metabolism of Dextromethorphan can be decreased when combined with Nevirapine.
Atorvastatin Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Dextromethorphan.
Dolasetron Dolasetron The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Dolasetron.
Bisacodyl Bisacodyl The therapeutic efficacy of Bisacodyl can be decreased when used in combination with Dextromethorphan.
Candesartan Candesartan The metabolism of Dextromethorphan can be decreased when combined with Candesartan.
Cilostazol Cilostazol The metabolism of Cilostazol can be decreased when combined with Dextromethorphan.
Clopidogrel Clopidogrel The metabolism of Clopidogrel can be decreased when combined with Dextromethorphan.
Diphenoxylate Diphenoxylate The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Diphenoxylate.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The metabolism of Dextromethorphan can be decreased when combined with Erythromycin.
Fenofibrate Fenofibrate The metabolism of Dextromethorphan can be decreased when combined with Fenofibrate.
Guanfacine Guanfacine The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Guanfacine.
Magnesium Hydroxide Magnesium Hydroxide The therapeutic efficacy of Magnesium hydroxide can be decreased when used in combination with Dextromethorphan.
Magnesium Oxide Magnesium Oxide The therapeutic efficacy of Magnesium oxide can be decreased when used in combination with Dextromethorphan.
Naratriptan Naratriptan The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Naratriptan.
Paregoric Paregoric The risk or severity of adverse effects can be increased when Morphine is combined with Dextromethorphan.
Penbutolol Penbutolol The metabolism of Dextromethorphan can be decreased when combined with Acebutolol.
Pentazocine Pentazocine The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Pentazocine.
Polyethylene glycol-electrolyte solution (PEG-ES) Polyethylene glycol-electrolyte solution (PEG-ES) The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Dextromethorphan.
Psyllium Psyllium The therapeutic efficacy of Plantago seed can be decreased when used in combination with Dextromethorphan.
Ranitidine Ranitidine The metabolism of Dextromethorphan can be decreased when combined with Ranitidine.
Reserpine Reserpine The metabolism of Dextromethorphan can be increased when combined with Reserpine.
Rizatriptan Rizatriptan The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Rizatriptan.
Sumatriptan Sumatriptan The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Sumatriptan.
Tacrolimus Tacrolimus The metabolism of Tacrolimus can be decreased when combined with Dextromethorphan.
Tizanidine Tizanidine The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Tizanidine.
Triamcinolone Triamcinolone The metabolism of Dextromethorphan can be increased when combined with Triamcinolone.
Zolmitriptan Zolmitriptan The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Dextromethorphan.
Fluconazole Injection Fluconazole Injection The metabolism of Dextromethorphan can be decreased when combined with Fluconazole.
Hydromorphone Injection Hydromorphone Injection The risk or severity of adverse effects can be increased when Hydromorphone is combined with Dextromethorphan.
Meperidine Injection Meperidine Injection The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Meperidine.
Metoclopramide Injection Metoclopramide Injection The therapeutic efficacy of Metoclopramide can be decreased when used in combination with Dextromethorphan.
Metronidazole Injection Metronidazole Injection The metabolism of Metronidazole can be decreased when combined with Dextromethorphan.
Morphine Injection Morphine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Dextromethorphan.
Zidovudine Injection Zidovudine Injection The metabolism of Dextromethorphan can be decreased when combined with Zidovudine.
Altretamine Altretamine The risk or severity of serotonin syndrome can be increased when Amphetamine is combined with Dextromethorphan.
Cyclosporine Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Dextromethorphan.
Ondansetron Ondansetron The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Ondansetron.
Granisetron Granisetron The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Granisetron.
Torsemide Torsemide The metabolism of Dextromethorphan can be decreased when combined with Torasemide.
Olanzapine Olanzapine The risk or severity of adverse effects can be increased when Olanzapine is combined with Dextromethorphan.
Alosetron Alosetron The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Alosetron.
Entacapone Entacapone The risk or severity of adverse effects can be increased when Entacapone is combined with Dextromethorphan.
Hydroxychloroquine Hydroxychloroquine The metabolism of Dextromethorphan can be decreased when combined with Hydroxychloroquine.
Meloxicam Meloxicam The metabolism of Meloxicam can be decreased when combined with Dextromethorphan.
Oxcarbazepine Oxcarbazepine The metabolism of Dextromethorphan can be increased when combined with Oxcarbazepine.
Zaleplon Zaleplon The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Zaleplon.
Anakinra Anakinra The metabolism of Dextromethorphan can be increased when combined with Anakinra.
Desloratadine Desloratadine The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Desloratadine.
Linezolid Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Dextromethorphan.
Rivastigmine Rivastigmine The therapeutic efficacy of Dextromethorphan can be decreased when used in combination with Rivastigmine.
Trimipramine Trimipramine The metabolism of Trimipramine can be decreased when combined with Dextromethorphan.
Etanercept Injection Etanercept Injection The metabolism of Dextromethorphan can be increased when combined with Etanercept.
Glycopyrrolate Glycopyrrolate Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium.
Modafinil Modafinil The metabolism of Dextromethorphan can be increased when combined with Modafinil.
Sirolimus Sirolimus The metabolism of Sirolimus can be decreased when combined with Dextromethorphan.
Dutasteride Dutasteride The metabolism of Dutasteride can be decreased when combined with Dextromethorphan.
Epinephrine Injection Epinephrine Injection The metabolism of Dextromethorphan can be decreased when combined with Epinephrine.
Eplerenone Eplerenone The metabolism of Eplerenone can be decreased when combined with Dextromethorphan.
Escitalopram Escitalopram The risk or severity of serotonin syndrome can be increased when Dextromethorphan is combined with Escitalopram.
Zonisamide Zonisamide The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Zonisamide.
Adalimumab Injection Adalimumab Injection The metabolism of Dextromethorphan can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Aripiprazole.
Atomoxetine Atomoxetine The risk or severity of adverse effects can be increased when Atomoxetine is combined with Dextromethorphan.
Dexmethylphenidate Dexmethylphenidate The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Dexmethylphenidate.
Atazanavir Atazanavir The metabolism of Atazanavir can be decreased when combined with Dextromethorphan.
Almotriptan Almotriptan The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Almotriptan.
Eletriptan Eletriptan The risk or severity of adverse effects can be increased when Eletriptan is combined with Dextromethorphan.
Mefloquine Mefloquine The therapeutic efficacy of Dextromethorphan can be decreased when used in combination with Mefloquine.
Polyethylene Glycol 3350 Polyethylene Glycol 3350 The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Dextromethorphan.
Rosuvastatin Rosuvastatin The metabolism of Rosuvastatin can be decreased when combined with Dextromethorphan.
Vardenafil Vardenafil The metabolism of Vardenafil can be decreased when combined with Dextromethorphan.
Aprepitant Aprepitant The metabolism of Dextromethorphan can be decreased when combined with Aprepitant.
Memantine Memantine The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Memantine.
Tegaserod Tegaserod The metabolism of Tegaserod can be decreased when combined with Dextromethorphan.
Tadalafil Tadalafil The metabolism of Tadalafil can be decreased when combined with Dextromethorphan.
Frovatriptan Frovatriptan The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Frovatriptan.
Progesterone Progesterone The metabolism of Dextromethorphan can be decreased when combined with Progesterone.
Apomorphine Injection Apomorphine Injection The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Apomorphine.
Infliximab Injection Infliximab Injection The metabolism of Dextromethorphan can be increased when combined with Infliximab.
Oxandrolone Oxandrolone The metabolism of Dextromethorphan can be decreased when combined with Oxandrolone.
Protriptyline Protriptyline The risk or severity of adverse effects can be increased when Protriptyline is combined with Dextromethorphan.
Duloxetine Duloxetine The metabolism of Duloxetine can be decreased when combined with Dextromethorphan.
Norethindrone Norethindrone The metabolism of Norethisterone can be decreased when combined with Dextromethorphan.
Trospium Trospium Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Trospium.
Bosentan Bosentan The metabolism of Dextromethorphan can be increased when combined with Bosentan.
Cinacalcet Cinacalcet The metabolism of Dextromethorphan can be decreased when combined with Cinacalcet.
Erlotinib Erlotinib The metabolism of Erlotinib can be decreased when combined with Dextromethorphan.
Eszopiclone Eszopiclone The risk or severity of CNS depression can be increased when Dextromethorphan is combined with Eszopiclone.
Solifenacin Solifenacin Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Voriconazole Voriconazole The metabolism of Dextromethorphan can be decreased when combined with Voriconazole.
Dextroamphetamine Dextroamphetamine The risk or severity of serotonin syndrome can be increased when Amphetamine is combined with Dextromethorphan.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The metabolism of Dextromethorphan can be increased when combined with Peginterferon alfa-2b.
Sodium Oxybate Sodium Oxybate Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Dextromethorphan.
Isocarboxazid Isocarboxazid The risk or severity of serotonin syndrome can be increased when Isocarboxazid is combined with Dextromethorphan.
Ramelteon Ramelteon The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Ramelteon.
Darifenacin Darifenacin The metabolism of Darifenacin can be decreased when combined with Dextromethorphan.
Fentanyl Fentanyl The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Fentanyl.
Pregabalin Pregabalin The therapeutic efficacy of Dextromethorphan can be increased when used in combination with Pregabalin.
Tipranavir Tipranavir The metabolism of Tipranavir can be decreased when combined with Dextromethorphan.
Felbamate Felbamate The metabolism of Dextromethorphan can be decreased when combined with Felbamate.
Ranolazine Ranolazine The serum concentration of Dextromethorphan can be increased when it is combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Dextromethorphan can be increased when combined with Abatacept.
Rasagiline Rasagiline The risk or severity of serotonin syndrome can be increased when Rasagiline is combined with Dextromethorphan.
Imatinib Imatinib The metabolism of Dextromethorphan can be decreased when combined with Imatinib.
Gefitinib Gefitinib The metabolism of Dextromethorphan can be decreased when combined with Gefitinib.
Paliperidone Paliperidone The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Paliperidone.
Bortezomib Bortezomib The metabolism of Dextromethorphan can be decreased when combined with Bortezomib.
Lubiprostone Lubiprostone The therapeutic efficacy of Lubiprostone can be decreased when used in combination with Dextromethorphan.
Primaquine Primaquine The metabolism of Dextromethorphan can be decreased when combined with Primaquine.
Dimenhydrinate Dimenhydrinate The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Dimenhydrinate.
Lisdexamfetamine Lisdexamfetamine The risk or severity of serotonin syndrome can be increased when Dextromethorphan is combined with Lisdexamfetamine.
Nabilone Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Dextromethorphan.
Sorafenib Sorafenib The metabolism of Dextromethorphan can be decreased when combined with Sorafenib.
Sunitinib Sunitinib The metabolism of Sunitinib can be decreased when combined with Dextromethorphan.
Dronabinol Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Dextromethorphan.
Lapatinib Lapatinib The metabolism of Lapatinib can be decreased when combined with Dextromethorphan.
Levocetirizine Levocetirizine The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Levocetirizine.
Dasatinib Dasatinib The metabolism of Dasatinib can be decreased when combined with Dextromethorphan.
Mexiletine Mexiletine The metabolism of Dextromethorphan can be decreased when combined with Mexiletine.
Armodafinil Armodafinil The metabolism of Dextromethorphan can be increased when combined with Armodafinil.
Paclitaxel (with polyoxyethylated castor oil) Injection Paclitaxel (with polyoxyethylated castor oil) Injection The therapeutic efficacy of Castor oil can be decreased when used in combination with Dextromethorphan.
Temsirolimus Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Dextromethorphan.
Nilotinib Nilotinib The metabolism of Dextromethorphan can be decreased when combined with Nilotinib.
Bexarotene Bexarotene The metabolism of Dextromethorphan can be decreased when combined with Bexarotene.
Budesonide Budesonide The metabolism of Dextromethorphan can be increased when combined with Budesonide.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Dextromethorphan can be decreased when combined with Chloramphenicol.
Betaine Betaine The therapeutic efficacy of Dextromethorphan can be decreased when used in combination with Glycine betaine.
OnabotulinumtoxinA Injection OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Botulinum toxin type A.
RimabotulinumtoxinB Injection RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Botulinum Toxin Type B.
Etravirine Etravirine The metabolism of Dextromethorphan can be decreased when combined with Etravirine.
Desvenlafaxine Desvenlafaxine The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Desvenlafaxine.
Cevimeline Cevimeline The metabolism of Dextromethorphan can be decreased when combined with Cevimeline.
Nebivolol Nebivolol The metabolism of Nebivolol can be decreased when combined with Dextromethorphan.
Tretinoin Tretinoin The metabolism of Tretinoin can be decreased when combined with Dextromethorphan.
Flecainide Flecainide The metabolism of Flecainide can be decreased when combined with Dextromethorphan.
Certolizumab Injection Certolizumab Injection The metabolism of Dextromethorphan can be increased when combined with Certolizumab pegol.
Irinotecan Injection Irinotecan Injection The metabolism of Irinotecan can be decreased when combined with Dextromethorphan.
Praziquantel Praziquantel The metabolism of Praziquantel can be decreased when combined with Dextromethorphan.
Rufinamide Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Dextromethorphan.
Midazolam Midazolam The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Midazolam.
Naltrexone Injection Naltrexone Injection The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Naltrexone.
Eltrombopag Eltrombopag The metabolism of Dextromethorphan can be decreased when combined with Eltrombopag.
Milnacipran Milnacipran The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Milnacipran.
Sodium Phosphate Sodium Phosphate The therapeutic efficacy of Sodium phosphate, monobasic can be decreased when used in combination with Dextromethorphan.
Fesoterodine Fesoterodine Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Fesoterodine.
Betaxolol Betaxolol The metabolism of Dextromethorphan can be decreased when combined with Betaxolol.
Iloperidone Iloperidone The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Iloperidone.
Prasugrel Prasugrel The metabolism of Prasugrel can be decreased when combined with Dextromethorphan.
Lacosamide Lacosamide The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Lacosamide.
Everolimus Everolimus The metabolism of Dextromethorphan can be decreased when combined with Everolimus.
Dronedarone Dronedarone The metabolism of Dronedarone can be decreased when combined with Dextromethorphan.
AbobotulinumtoxinA Injection AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Botulinum toxin type A.
Palonosetron Injection Palonosetron Injection The risk or severity of adverse effects can be increased when Palonosetron is combined with Dextromethorphan.
Saxagliptin Saxagliptin The metabolism of Saxagliptin can be decreased when combined with Dextromethorphan.
Romidepsin Injection Romidepsin Injection The metabolism of Romidepsin can be decreased when combined with Dextromethorphan.
Tapentadol Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Dextromethorphan.
Golimumab Injection Golimumab Injection The metabolism of Dextromethorphan can be increased when combined with Golimumab.
Pazopanib Pazopanib The metabolism of Dextromethorphan can be decreased when combined with Pazopanib.
Asenapine Asenapine The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Asenapine.
Vigabatrin Vigabatrin The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Vigabatrin.
Pitavastatin Pitavastatin The metabolism of Pitavastatin can be decreased when combined with Dextromethorphan.
Levonorgestrel Levonorgestrel The metabolism of Dextromethorphan can be decreased when combined with Levonorgestrel.
Oxymorphone Oxymorphone The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Oxymorphone.
Tocilizumab Injection Tocilizumab Injection The metabolism of Dextromethorphan can be increased when combined with Tocilizumab.
IncobotulinumtoxinA Injection IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Botulinum toxin type A.
Cabazitaxel Injection Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Dextromethorphan.
Lurasidone Lurasidone The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Lurasidone.
Vilazodone Vilazodone The metabolism of Vilazodone can be decreased when combined with Dextromethorphan.
Terbutaline Injection Terbutaline Injection The therapeutic efficacy of Dextromethorphan can be decreased when used in combination with Terbutaline.
Rilpivirine Rilpivirine The metabolism of Dextromethorphan can be decreased when combined with Rilpivirine.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Cyclophosphamide can be decreased when combined with Dextromethorphan.
Abiraterone Abiraterone The metabolism of Dextromethorphan can be decreased when combined with Abiraterone.
Rivaroxaban Rivaroxaban The metabolism of Rivaroxaban can be decreased when combined with Dextromethorphan.
Ticagrelor Ticagrelor The metabolism of Dextromethorphan can be decreased when combined with Ticagrelor.
Clobazam Clobazam The metabolism of Dextromethorphan can be decreased when combined with Clobazam.
Vemurafenib Vemurafenib The metabolism of Dextromethorphan can be decreased when combined with Vemurafenib.
Vismodegib Vismodegib The metabolism of Dextromethorphan can be decreased when combined with Vismodegib.
Ivacaftor Ivacaftor The metabolism of Ivacaftor can be decreased when combined with Dextromethorphan.
Axitinib Axitinib The metabolism of Axitinib can be decreased when combined with Dextromethorphan.
Crizotinib Crizotinib The metabolism of Dextromethorphan can be decreased when combined with Crizotinib.
Cabergoline Cabergoline The risk or severity of adverse effects can be increased when Cabergoline is combined with Dextromethorphan.
Ambrisentan Ambrisentan The metabolism of Ambrisentan can be decreased when combined with Dextromethorphan.
Ezogabine Ezogabine The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Tiagabine.
Enzalutamide Enzalutamide The metabolism of Enzalutamide can be increased when combined with Dextromethorphan.
Mirabegron Mirabegron The metabolism of Mirabegron can be decreased when combined with Dextromethorphan.
Regorafenib Regorafenib The metabolism of Dextromethorphan can be decreased when combined with Regorafenib.
Linaclotide Linaclotide The therapeutic efficacy of Linaclotide can be decreased when used in combination with Dextromethorphan.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Dextromethorphan.
Alogliptin Alogliptin The metabolism of Alogliptin can be decreased when combined with Dextromethorphan.
Ponatinib Ponatinib The metabolism of Ponatinib can be decreased when combined with Dextromethorphan.
Pomalidomide Pomalidomide The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Pomalidomide.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be decreased when combined with Dextromethorphan.
Apixaban Apixaban The metabolism of Apixaban can be decreased when combined with Dextromethorphan.
Dabrafenib Dabrafenib The metabolism of Dextromethorphan can be increased when combined with Dabrafenib.
Ospemifene Ospemifene The metabolism of Ospemifene can be decreased when combined with Dextromethorphan.
Levomilnacipran Levomilnacipran The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Levomilnacipran.
Vortioxetine Vortioxetine The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Vortioxetine.
Perampanel Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Dextromethorphan.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Dextromethorphan.
Ketorolac Injection Ketorolac Injection The metabolism of Dextromethorphan can be decreased when combined with Ketorolac.
Dapagliflozin Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Dextromethorphan.
Apremilast Apremilast The metabolism of Dextromethorphan can be increased when combined with Apremilast.
Ceritinib Ceritinib The metabolism of Dextromethorphan can be decreased when combined with Ceritinib.
Siltuximab Injection Siltuximab Injection The metabolism of Dextromethorphan can be increased when combined with Siltuximab.
Eslicarbazepine Eslicarbazepine The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Eslicarbazepine.
Testosterone Injection Testosterone Injection The metabolism of Testosterone can be decreased when combined with Dextromethorphan.
Oritavancin Injection Oritavancin Injection The metabolism of Dextromethorphan can be decreased when combined with Oritavancin.
Hydrocodone Hydrocodone Hydrocodone may increase the central nervous system depressant (CNS depressant) activities of Dextromethorphan.
Suvorexant Suvorexant Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Olaparib Olaparib The metabolism of Olaparib can be decreased when combined with Dextromethorphan.
Methamphetamine Methamphetamine The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Metamfetamine.
Tasimelteon Tasimelteon The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Tasimelteon.
Secukinumab Injection Secukinumab Injection The metabolism of Dextromethorphan can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Risperidone.
Lenvatinib Lenvatinib The metabolism of Dextromethorphan can be decreased when combined with Lenvatinib.
Naloxegol Naloxegol The metabolism of Dextromethorphan can be decreased when combined with Naloxegol.
Panobinostat Panobinostat The metabolism of Dextromethorphan can be decreased when combined with Panobinostat.
Haloperidol Injection Haloperidol Injection The risk or severity of CNS depression can be increased when Dextromethorphan is combined with Haloperidol.
Flibanserin Flibanserin The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Flibanserin.
Rolapitant Rolapitant The metabolism of Dextromethorphan can be decreased when combined with Rolapitant.
Daclatasvir Daclatasvir The metabolism of Daclatasvir can be decreased when combined with Dextromethorphan.
Brexpiprazole Brexpiprazole The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Brexpiprazole.
Ziprasidone Injection Ziprasidone Injection The risk or severity of adverse effects can be increased when Ziprasidone is combined with Dextromethorphan.
Cariprazine Cariprazine The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Cariprazine.
Eluxadoline Eluxadoline The risk or severity of constipation can be increased when Dextromethorphan is combined with Eluxadoline.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Dextromethorphan.
Lesinurad Lesinurad The metabolism of Lesinurad can be decreased when combined with Dextromethorphan.
Dexamethasone Injection Dexamethasone Injection The metabolism of Dextromethorphan can be increased when combined with Dexamethasone.
Brivaracetam Injection Brivaracetam Injection The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Brivaracetam.
Cobicistat Cobicistat The metabolism of Dextromethorphan can be decreased when combined with Cobicistat.
Pimavanserin Pimavanserin The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Pimavanserin.
Rucaparib Rucaparib The metabolism of Dextromethorphan can be decreased when combined with Rucaparib.
Doxepin (Insomnia) Doxepin (Insomnia) Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Doxepin.
Plecanatide Plecanatide The therapeutic efficacy of Plecanatide can be decreased when used in combination with Dextromethorphan.
Deutetrabenazine Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Dextromethorphan.
Valbenazine Valbenazine The metabolism of Valbenazine can be decreased when combined with Dextromethorphan.
Deflazacort Deflazacort The metabolism of Dextromethorphan can be increased when combined with Deflazacort.
Safinamide Safinamide The risk or severity of serotonin syndrome can be increased when Safinamide is combined with Dextromethorphan.
Midostaurin Midostaurin The metabolism of Dextromethorphan can be decreased when combined with Midostaurin.
Enasidenib Enasidenib The metabolism of Dextromethorphan can be decreased when combined with Enasidenib.
Copanlisib Injection Copanlisib Injection The metabolism of Copanlisib can be decreased when combined with Dextromethorphan.
Delafloxacin Delafloxacin The metabolism of Dextromethorphan can be increased when combined with Delafloxacin.
Acalabrutinib Acalabrutinib The metabolism of Dextromethorphan can be decreased when combined with Acalabrutinib.
Letermovir Letermovir The metabolism of Dextromethorphan can be decreased when combined with Letermovir.
Tetrabenazine Tetrabenazine The metabolism of Tetrabenazine can be decreased when combined with Dextromethorphan.
Buprenorphine Injection Buprenorphine Injection Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Apalutamide Apalutamide The metabolism of Dextromethorphan can be increased when combined with Apalutamide.
Avatrombopag Avatrombopag The metabolism of Dextromethorphan can be increased when combined with Avatrombopag.
Lofexidine Lofexidine The therapeutic efficacy of Dextromethorphan can be increased when used in combination with Lofexidine.
Eliglustat Eliglustat The metabolism of Dextromethorphan can be decreased when combined with Eliglustat.
Encorafenib Encorafenib The metabolism of Encorafenib can be decreased when combined with Dextromethorphan.
Elagolix Elagolix The metabolism of Elagolix can be decreased when combined with Dextromethorphan.
Doravirine Doravirine The metabolism of Doravirine can be decreased when combined with Dextromethorphan.
Tafenoquine Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Dextromethorphan.
Cannabidiol Cannabidiol The risk or severity of adverse effects can be increased when Cannabidiol is combined with Dextromethorphan.
Dacomitinib Dacomitinib The metabolism of Dextromethorphan can be decreased when combined with Dacomitinib.
Stiripentol Stiripentol The metabolism of Dextromethorphan can be decreased when combined with Stiripentol.
Gilteritinib Gilteritinib The therapeutic efficacy of Dextromethorphan can be decreased when used in combination with Gilteritinib.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Dextromethorphan.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Dextromethorphan.
Rifamycin Rifamycin The metabolism of Dextromethorphan can be decreased when combined with Rifamycin.
Prucalopride Prucalopride The therapeutic efficacy of Prucalopride can be decreased when used in combination with Dextromethorphan.
Magnesium Citrate Magnesium Citrate The therapeutic efficacy of Magnesium citrate can be decreased when used in combination with Dextromethorphan.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Dextromethorphan can be increased when combined with Emapalumab.
Siponimod Siponimod The metabolism of Siponimod can be decreased when combined with Dextromethorphan.
Erdafitinib Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Dextromethorphan.
Alpelisib Alpelisib The serum concentration of Dextromethorphan can be decreased when it is combined with Alpelisib.
Brexanolone Injection Brexanolone Injection The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Brexanolone.
Solriamfetol Solriamfetol The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Solriamfetol.
Triclabendazole Triclabendazole The metabolism of Dextromethorphan can be decreased when combined with Triclabendazole.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Dextromethorphan.
Pitolisant Pitolisant The serum concentration of Dextromethorphan can be decreased when it is combined with Pitolisant.
Fedratinib Fedratinib The metabolism of Dextromethorphan can be decreased when combined with Fedratinib.
Phenytoin Injection Phenytoin Injection The metabolism of Dextromethorphan can be decreased when combined with Phenytoin.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Fosphenytoin can be decreased when combined with Dextromethorphan.
Voxelotor Voxelotor The metabolism of Voxelotor can be decreased when combined with Dextromethorphan.
Avapritinib Avapritinib The metabolism of Avapritinib can be decreased when combined with Dextromethorphan.
Lumateperone Lumateperone The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Lumateperone.
Lasmiditan Lasmiditan The risk or severity of serotonin syndrome can be increased when Dextromethorphan is combined with Lasmiditan.
Cenobamate Cenobamate The serum concentration of Dextromethorphan can be decreased when it is combined with Cenobamate.
Selumetinib Selumetinib The metabolism of Selumetinib can be decreased when combined with Dextromethorphan.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Dextromethorphan.
Lemborexant Lemborexant The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Lemborexant.
Fenfluramine Fenfluramine The risk or severity of serotonin syndrome can be increased when Dextromethorphan is combined with Fenfluramine.
Pralsetinib Pralsetinib The metabolism of Dextromethorphan can be decreased when combined with Pralsetinib.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Dextromethorphan can be decreased when it is combined with Satralizumab.
Viloxazine Viloxazine The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Viloxazine.
Theophylline Theophylline The metabolism of Dextromethorphan can be decreased when combined with Theophylline.
Indomethacin Indomethacin The metabolism of Dextromethorphan can be decreased when combined with Indomethacin.
Mefenamic Acid Mefenamic Acid The metabolism of Mefenamic acid can be decreased when combined with Dextromethorphan.
Naproxen Naproxen The metabolism of Naproxen can be decreased when combined with Dextromethorphan.
Trazodone Trazodone The risk or severity of serotonin syndrome can be increased when Trazodone is combined with Dextromethorphan.
Hydroxyurea Hydroxyurea The metabolism of Dextromethorphan can be decreased when combined with Hydroxyurea.
Floxuridine Floxuridine The metabolism of Dextromethorphan can be decreased when combined with Floxuridine.
Phenobarbital Phenobarbital The metabolism of Dextromethorphan can be decreased when combined with Phenobarbital.
Metaxalone Metaxalone The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Metaxalone.
Levorphanol Levorphanol The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Levorphanol.
Primidone Primidone The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Primidone.
Methsuximide Methsuximide The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Methsuximide.
Diethylpropion Diethylpropion The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Diethylpropion.
Chlorpromazine Chlorpromazine The metabolism of Dextromethorphan can be decreased when combined with Chlorpromazine.
Diazepam Diazepam The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Diazepam.
Oxazepam Oxazepam The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Oxazepam.
Flurazepam Flurazepam The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Flurazepam.
Clorazepate Clorazepate The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Clorazepic acid.
Lorazepam Lorazepam The risk or severity of adverse effects can be increased when Lorazepam is combined with Dextromethorphan.
Amantadine Amantadine The risk or severity of serotonin syndrome can be increased when Dextromethorphan is combined with Amantadine.
Codeine Codeine The risk or severity of adverse effects can be increased when Codeine is combined with Dextromethorphan.
Meprobamate Meprobamate The risk or severity of adverse effects can be increased when Meprobamate is combined with Dextromethorphan.
Chlordiazepoxide Chlordiazepoxide The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Dextromethorphan.
Bromocriptine Bromocriptine The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Bromocriptine.
Tranylcypromine Tranylcypromine The risk or severity of serotonin syndrome can be increased when Tranylcypromine is combined with Dextromethorphan.
Phenelzine Phenelzine The risk or severity of serotonin syndrome can be increased when Phenelzine is combined with Dextromethorphan.
Procarbazine Procarbazine The risk or severity of serotonin syndrome can be increased when Procarbazine is combined with Dextromethorphan.
Ergoloid Mesylates Ergoloid Mesylates The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Ergoloid mesylate.
Minocycline Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Dextromethorphan.
Prochlorperazine Prochlorperazine The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Prochlorperazine.
Thioridazine Thioridazine The metabolism of Dextromethorphan can be decreased when combined with Thioridazine.
Trifluoperazine Trifluoperazine The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Trifluoperazine.
Dapsone Dapsone The metabolism of Dextromethorphan can be decreased when combined with Dapsone.
Sulfadiazine Sulfadiazine The metabolism of Dextromethorphan can be decreased when combined with Sulfadiazine.
Oxycodone Oxycodone The risk or severity of adverse effects can be increased when Oxycodone is combined with Dextromethorphan.
Methadone Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Dextromethorphan.
Oxybutynin Oxybutynin The metabolism of Oxybutynin can be decreased when combined with Dextromethorphan.
Benztropine Benztropine Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Benzatropine.
Maprotiline Maprotiline The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Maprotiline.
Ibuprofen Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Dextromethorphan.
Trihexyphenidyl Trihexyphenidyl Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Trihexyphenidyl.
Orphenadrine Orphenadrine Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Perphenazine Perphenazine The metabolism of Dextromethorphan can be decreased when combined with Perphenazine.
Fluphenazine Fluphenazine The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Fluphenazine.
Phentermine Phentermine The risk or severity of serotonin syndrome can be increased when Phentermine is combined with Dextromethorphan.
Amoxapine Amoxapine The metabolism of Amoxapine can be decreased when combined with Dextromethorphan.
Hydrocortisone Hydrocortisone The metabolism of Hydrocortisone can be decreased when combined with Dextromethorphan.
Doxorubicin Doxorubicin The metabolism of Dextromethorphan can be decreased when combined with Doxorubicin.
Mechlorethamine Mechlorethamine The therapeutic efficacy of Dextromethorphan can be decreased when used in combination with Mechlorethamine.
Pyridostigmine Pyridostigmine The therapeutic efficacy of Dextromethorphan can be decreased when used in combination with Pyridostigmine.
Carbamazepine Carbamazepine The metabolism of Carbamazepine can be decreased when combined with Dextromethorphan.
Molindone Molindone The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Molindone.
Clonidine Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Dextromethorphan.
Cimetidine Cimetidine The metabolism of Dextromethorphan can be decreased when combined with Cimetidine.
Warfarin Warfarin The metabolism of Dextromethorphan can be decreased when combined with Warfarin.
Clonazepam Clonazepam The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Clonazepam.
Loperamide Loperamide The metabolism of Loperamide can be decreased when combined with Dextromethorphan.
Daunorubicin Daunorubicin The metabolism of Dextromethorphan can be increased when combined with Daunorubicin.
Loxapine Loxapine The risk or severity of adverse effects can be increased when Loxapine is combined with Dextromethorphan.
Chloroquine Chloroquine The metabolism of Chloroquine can be decreased when combined with Dextromethorphan.
Quinine Quinine The metabolism of Dextromethorphan can be decreased when combined with Quinine.
Ethosuximide Ethosuximide The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Ethosuximide.
Lactulose Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Dextromethorphan.
Sulfinpyrazone Sulfinpyrazone The metabolism of Dextromethorphan can be decreased when combined with Sulfinpyrazone.
Chlorothiazide Chlorothiazide The serum concentration of Chlorothiazide can be increased when it is combined with Dextromethorphan.
Chlorthalidone Chlorthalidone The serum concentration of Chlorthalidone can be increased when it is combined with Dextromethorphan.
Metolazone Metolazone The serum concentration of Metolazone can be increased when it is combined with Dextromethorphan.
Clindamycin Injection Clindamycin Injection The metabolism of Clindamycin can be decreased when combined with Dextromethorphan.
Secobarbital Secobarbital The risk or severity of adverse effects can be increased when Secobarbital is combined with Dextromethorphan.
Desipramine Desipramine The metabolism of Desipramine can be decreased when combined with Dextromethorphan.
Amitriptyline Amitriptyline The metabolism of Dextromethorphan can be decreased when combined with Amitriptyline.
Imipramine Imipramine The metabolism of Imipramine can be decreased when combined with Dextromethorphan.
Probenecid Probenecid The metabolism of Dextromethorphan can be decreased when combined with Probenecid.
Procainamide Procainamide The metabolism of Procainamide can be decreased when combined with Dextromethorphan.
Isoniazid Isoniazid The metabolism of Dextromethorphan can be decreased when combined with Isoniazid.
Rifampin Rifampin The metabolism of Dextromethorphan can be increased when combined with Rifampicin.
Disopyramide Disopyramide Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Disopyramide.
Valproic Acid Valproic Acid The risk or severity of adverse effects can be increased when Valproic acid is combined with Dextromethorphan.
Tamoxifen Tamoxifen The metabolism of Tamoxifen can be decreased when combined with Dextromethorphan.
Butabarbital Butabarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Dextromethorphan.
Methimazole Methimazole The metabolism of Dextromethorphan can be decreased when combined with Methimazole.
Chlorpropamide Chlorpropamide The metabolism of Chlorpropamide can be decreased when combined with Dextromethorphan.
Tolbutamide Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Dextromethorphan.
Tolazamide Tolazamide The metabolism of Tolazamide can be decreased when combined with Dextromethorphan.
Cyclobenzaprine Cyclobenzaprine The risk or severity of CNS depression can be increased when Dextromethorphan is combined with Cyclobenzaprine.
Niacin Niacin The metabolism of Dextromethorphan can be decreased when combined with Niacin.
Baclofen Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Dextromethorphan.
Cyproheptadine Cyproheptadine Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Cyproheptadine.
Clemastine Clemastine The metabolism of Dextromethorphan can be decreased when combined with Clemastine.
Meclizine Meclizine The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Meclizine.
Methyclothiazide Methyclothiazide The serum concentration of Methyclothiazide can be increased when it is combined with Dextromethorphan.
Hydrochlorothiazide Hydrochlorothiazide The serum concentration of Hydrochlorothiazide can be increased when it is combined with Dextromethorphan.
Dantrolene Dantrolene The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Dantrolene.
Chlorzoxazone Chlorzoxazone The risk or severity of adverse effects can be increased when Chlorzoxazone is combined with Dextromethorphan.
Carisoprodol Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Dextromethorphan.
Methocarbamol Methocarbamol The risk or severity of adverse effects can be increased when Methocarbamol is combined with Dextromethorphan.
Disulfiram Disulfiram The metabolism of Disulfiram can be decreased when combined with Dextromethorphan.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The metabolism of Propranolol can be decreased when combined with Dextromethorphan.
Nortriptyline Nortriptyline The metabolism of Nortriptyline can be decreased when combined with Dextromethorphan.
Nadolol Nadolol The metabolism of Nadolol can be decreased when combined with Dextromethorphan.
Butorphanol Injection Butorphanol Injection The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Butorphanol.
Nalbuphine Injection Nalbuphine Injection The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Nalbuphine.
Trimethobenzamide Trimethobenzamide The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Trimethobenzamide.
Flavoxate Flavoxate Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Flavoxate.
Fluorouracil Injection Fluorouracil Injection The metabolism of Dextromethorphan can be decreased when combined with Fluorouracil.
Acetazolamide Acetazolamide The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Acetazolamide.
Ketoconazole Ketoconazole The metabolism of Dextromethorphan can be decreased when combined with Ketoconazole.
Pyrantel Pyrantel The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Pyrantel.
Thiotepa Injection Thiotepa Injection The therapeutic efficacy of Dextromethorphan can be decreased when used in combination with Thiotepa.
Vincristine Injection Vincristine Injection The metabolism of Vincristine can be decreased when combined with Dextromethorphan.
Vinblastine Vinblastine The metabolism of Dextromethorphan can be decreased when combined with Vinblastine.
Metoprolol Metoprolol The metabolism of Dextromethorphan can be decreased when combined with Metoprolol.
Hydroxyzine Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Dextromethorphan.
Thiothixene Thiothixene The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Thiothixene.
Alprazolam Alprazolam The risk or severity of adverse effects can be increased when Alprazolam is combined with Dextromethorphan.
Temazepam Temazepam The risk or severity of adverse effects can be increased when Temazepam is combined with Dextromethorphan.
Triazolam Triazolam The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Triazolam.
Dicyclomine Dicyclomine Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine.
Hyoscyamine Hyoscyamine Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine.
Propantheline Propantheline Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Propantheline.
Trimethoprim Trimethoprim The metabolism of Dextromethorphan can be decreased when combined with Trimethoprim.
Diltiazem Diltiazem The metabolism of Dextromethorphan can be decreased when combined with Diltiazem.
Nifedipine Nifedipine The metabolism of Nifedipine can be decreased when combined with Dextromethorphan.
Timolol Timolol The metabolism of Dextromethorphan can be decreased when combined with Timolol.
Verapamil Verapamil The metabolism of Dextromethorphan can be decreased when combined with Verapamil.
Atenolol Atenolol The metabolism of Dextromethorphan can be decreased when combined with Atenolol.
Pindolol Pindolol The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Pindolol.
Cisplatin Injection Cisplatin Injection The metabolism of Dextromethorphan can be decreased when combined with Cisplatin.
Piroxicam Piroxicam The metabolism of Piroxicam can be decreased when combined with Dextromethorphan.
Etoposide Etoposide The metabolism of Etoposide can be decreased when combined with Dextromethorphan.
Glyburide Glyburide The metabolism of Dextromethorphan can be decreased when combined with Glyburide.
Glipizide Glipizide The metabolism of Glipizide can be decreased when combined with Dextromethorphan.
Indapamide Indapamide The serum concentration of Indapamide can be increased when it is combined with Dextromethorphan.
Pentamidine Injection Pentamidine Injection The metabolism of Pentamidine can be decreased when combined with Dextromethorphan.
Labetalol Labetalol The metabolism of Dextromethorphan can be decreased when combined with Labetalol.
Gemfibrozil Gemfibrozil The metabolism of Dextromethorphan can be decreased when combined with Gemfibrozil.
Pimozide Pimozide The metabolism of Pimozide can be decreased when combined with Dextromethorphan.
Flurbiprofen Flurbiprofen The metabolism of Flurbiprofen can be decreased when combined with Dextromethorphan.
Amiodarone Amiodarone The serum concentration of Amiodarone can be increased when it is combined with Dextromethorphan.
Buspirone Buspirone The risk or severity of serotonin syndrome can be increased when Buspirone is combined with Dextromethorphan.
Lovastatin Lovastatin The metabolism of Dextromethorphan can be decreased when combined with Lovastatin.
Ciprofloxacin Ciprofloxacin The metabolism of Dextromethorphan can be decreased when combined with Ciprofloxacin.
Diclofenac Diclofenac The metabolism of Diclofenac can be decreased when combined with Dextromethorphan.
Fluoxetine Fluoxetine The serum concentration of Dextromethorphan can be increased when it is combined with Fluoxetine.
Clozapine Clozapine The metabolism of Clozapine can be decreased when combined with Dextromethorphan.
Estazolam Estazolam The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Estazolam.
Idarubicin Idarubicin The metabolism of Idarubicin can be decreased when combined with Dextromethorphan.
Clarithromycin Clarithromycin The metabolism of Dextromethorphan can be decreased when combined with Clarithromycin.
Etodolac Etodolac The metabolism of Etodolac can be decreased when combined with Dextromethorphan.
Felodipine Felodipine The metabolism of Felodipine can be decreased when combined with Dextromethorphan.
Nabumetone Nabumetone The metabolism of Dextromethorphan can be decreased when combined with Nabumetone.
Simvastatin Simvastatin The metabolism of Simvastatin can be decreased when combined with Dextromethorphan.
Teniposide Injection Teniposide Injection The metabolism of Dextromethorphan can be decreased when combined with Teniposide.
Itraconazole Itraconazole The metabolism of Dextromethorphan can be decreased when combined with Itraconazole.
Atovaquone Atovaquone The metabolism of Dextromethorphan can be decreased when combined with Atovaquone.
Sotalol Sotalol The metabolism of Sotalol can be decreased when combined with Dextromethorphan.
Zolpidem Zolpidem Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Doxazosin Doxazosin The metabolism of Doxazosin can be decreased when combined with Dextromethorphan.
Omeprazole Omeprazole The metabolism of Dextromethorphan can be decreased when combined with Omeprazole.
Cisapride Cisapride The metabolism of Cisapride can be decreased when combined with Dextromethorphan.
Gabapentin Gabapentin The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Gabapentin.
Fluvastatin Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Dextromethorphan.
Venlafaxine Venlafaxine The metabolism of Dextromethorphan can be decreased when combined with Venlafaxine.
Nizatidine Nizatidine The therapeutic efficacy of Dextromethorphan can be decreased when used in combination with Nizatidine.
Fluvoxamine Fluvoxamine The metabolism of Fluvoxamine can be decreased when combined with Dextromethorphan.
Nefazodone Nefazodone The risk or severity of adverse effects can be increased when Nefazodone is combined with Dextromethorphan.
Lamotrigine Lamotrigine Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Lamotrigine.
Losartan Losartan The metabolism of Losartan can be decreased when combined with Dextromethorphan.
Tramadol Tramadol The risk or severity of serotonin syndrome can be increased when Tramadol is combined with Dextromethorphan.
Vinorelbine Injection Vinorelbine Injection The metabolism of Dextromethorphan can be decreased when combined with Vinorelbine.
Lansoprazole Lansoprazole The metabolism of Dextromethorphan can be decreased when combined with Lansoprazole.
Ifosfamide Injection Ifosfamide Injection The metabolism of Ifosfamide can be decreased when combined with Dextromethorphan.
Nicardipine Nicardipine The metabolism of Dextromethorphan can be decreased when combined with Nicardipine.
Bupropion Bupropion The metabolism of Dextromethorphan can be decreased when combined with Bupropion.
Ticlopidine Ticlopidine The metabolism of Dextromethorphan can be decreased when combined with Ticlopidine.
Saquinavir Saquinavir The metabolism of Dextromethorphan can be decreased when combined with Saquinavir.
Nisoldipine Nisoldipine The metabolism of Dextromethorphan can be decreased when combined with Nisoldipine.
Riluzole Riluzole The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Riluzole.
Glimepiride Glimepiride The metabolism of Dextromethorphan can be decreased when combined with Glimepiride.
Indinavir Indinavir The metabolism of Dextromethorphan can be decreased when combined with Indinavir.
Ritonavir Ritonavir The serum concentration of Dextromethorphan can be increased when it is combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The metabolism of Docetaxel can be decreased when combined with Dextromethorphan.
Clomipramine Clomipramine The metabolism of Clomipramine can be decreased when combined with Dextromethorphan.
Zafirlukast Zafirlukast The metabolism of Dextromethorphan can be decreased when combined with Zafirlukast.
Mirtazapine Mirtazapine Dextromethorphan may increase the serotonergic activities of Mirtazapine.
Topiramate Topiramate The risk or severity of adverse effects can be increased when Topiramate is combined with Dextromethorphan.
Zileuton Zileuton The metabolism of Zileuton can be decreased when combined with Dextromethorphan.
Valsartan Valsartan The metabolism of Dextromethorphan can be decreased when combined with Valsartan.
Pramipexole Pramipexole Dextromethorphan may increase the sedative activities of Pramipexole.
Donepezil Donepezil The therapeutic efficacy of Dextromethorphan can be decreased when used in combination with Donepezil.
Nelfinavir Nelfinavir The metabolism of Dextromethorphan can be decreased when combined with Nelfinavir.
Loratadine Loratadine Dextromethorphan may increase the anticholinergic activities of Loratadine.
Carvedilol Carvedilol The metabolism of Carvedilol can be decreased when combined with Dextromethorphan.
Nilutamide Nilutamide The metabolism of Dextromethorphan can be decreased when combined with Nilutamide.
Flutamide Flutamide The metabolism of Dextromethorphan can be decreased when combined with Flutamide.
Selegiline Selegiline The risk or severity of serotonin syndrome can be increased when Selegiline is combined with Dextromethorphan.
Bicalutamide Bicalutamide The metabolism of Dextromethorphan can be decreased when combined with Bicalutamide.
Sertraline Sertraline The risk or severity of adverse effects can be increased when Sertraline is combined with Dextromethorphan.
Propafenone Propafenone The metabolism of Dextromethorphan can be decreased when combined with Propafenone.
Irbesartan Irbesartan The metabolism of Irbesartan can be decreased when combined with Dextromethorphan.
Tamsulosin Tamsulosin The metabolism of Tamsulosin can be decreased when combined with Dextromethorphan.
Ropinirole Ropinirole Dextromethorphan may increase the sedative activities of Ropinirole.
Finasteride Finasteride The metabolism of Finasteride can be decreased when combined with Dextromethorphan.
Quetiapine Quetiapine Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Quetiapine.
Cetirizine Cetirizine The risk or severity of adverse effects can be increased when Cetirizine is combined with Dextromethorphan.
Paroxetine Paroxetine The metabolism of Dextromethorphan can be decreased when combined with Paroxetine.
Tolcapone Tolcapone The metabolism of Dextromethorphan can be decreased when combined with Tolcapone.
Citalopram Citalopram The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Citalopram.
Capecitabine Capecitabine The metabolism of Dextromethorphan can be decreased when combined with Capecitabine.
Efavirenz Efavirenz The metabolism of Dextromethorphan can be increased when combined with Efavirenz.
Sildenafil Sildenafil The metabolism of Dextromethorphan can be decreased when combined with Sildenafil.
Celecoxib Celecoxib The metabolism of Dextromethorphan can be decreased when combined with Celecoxib.
Rosiglitazone Rosiglitazone The metabolism of Dextromethorphan can be decreased when combined with Rosiglitazone.
Tolterodine Tolterodine Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Tolterodine.
Thalidomide Thalidomide Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Nateglinide Nateglinide The metabolism of Nateglinide can be decreased when combined with Dextromethorphan.
Galantamine Galantamine The therapeutic efficacy of Dextromethorphan can be decreased when used in combination with Galantamine.
Levetiracetam Levetiracetam The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Levetiracetam.
Rabeprazole Rabeprazole The metabolism of Dextromethorphan can be decreased when combined with Rabeprazole.
Terbinafine Terbinafine The metabolism of Dextromethorphan can be decreased when combined with Terbinafine.

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