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Bismuth subcitrate 140 MG / metronidazole 125 MG / tetracycline hydrochloride 125 MG Oral... — RxCUI 1294621

RxNorm drug concept · Semantic branded drug
RxCUI 1294621 Semantic branded drug · SBD ● Current RxNorm concept 2 FDA products 2 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1294621
Official nameBismuth subcitrate 140 MG / metronidazole 125 MG / tetracycline hydrochloride 125 MG Oral Capsule [Pylera]
Concept typeSemantic branded drug (SBD)
RxNorm statusCurrent RxNorm concept
Also known asPYLERA 140 MG / 125 MG / 125 MG Oral Capsule
FDA products mapped2
Package NDCs mapped2
Reported Medicaid activity (SDUD)9,571 prescriptions · 25 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Bismuth, Metronidazole, and Tetracycline: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • You have an H. pylori infection, which is a stubborn stomach bacteria that's notoriously hard to kill. Using three ingredients together — two different antibiotics (metronidazole a...
  • What exactly is this medication doing — why do I need three drugs at once?
  • No — this is one of the most important rules with this medication. You need to avoid alcohol completely during the entire 10-day course AND for at least 3 days after your last dose...
  • This is actually expected and harmless with this medication. Bismuth subcitrate potassium — one of the three ingredients — temporarily darkens the tongue and turns stools black or...
📖 Read our full Bismuth, Metronidazole, and Tetracycline guide →

🕸️ Concept Web — How Bismuth subcitrate 140 MG / metronidazole 125 MG... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Bismuth subcitrate 140 MG / metronidazole 125 MG / tetracycline hydrochloride 125 MG Oral Capsule [Pylera] RxCUI 1294621

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 5

    The active substance itself — no strength, form, or brand attached yet.

    • Bismuth subcitrate 47181
    • Metronidazole 6922
    • Tetracycline 10395
    • Bismuth subcitrate / metronidazole / tetracycline 1007769
    • Tetracycline hydrochloride 142446
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Pylera 705862
  3. Dose forms 13

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Bismuth subcitrate / metronidazole / tetracycline Oral Capsule 705860
    • Bismuth subcitrate / metronidazole / tetracycline hydrochloride Oral Capsule 2648018
    • Bismuth subcitrate / metronidazole / tetracycline Oral Product 1161817
    • Bismuth subcitrate / metronidazole / tetracycline Pill 1161818
    • Bismuth subcitrate / metronidazole / tetracycline hydrochloride Oral Product 2659155
    • Bismuth subcitrate / metronidazole / tetracycline hydrochloride Pill 2663130
    • Bismuth subcitrate / metronidazole / tetracycline Oral Capsule [Pylera] 705864
    • Bismuth subcitrate / metronidazole / tetracycline hydrochloride Oral Capsule [Pylera] 2655683
    • +5 more in this family
  4. Clinical & branded drugs 5

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 19 of 24 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Bismuth subcitrate 140 MG / metronidazole 125 MG / tetracycline hydrochloride 125 MG Oral Capsule SCD · 1294619
  • Bismuth subcitrate 140 MG SCDC · 705859
  • Metronidazole 125 MG SCDC · 335218
  • Tetracycline hydrochloride 125 MG SCDC · 1294618
  • Bismuth subcitrate / metronidazole / tetracycline Oral Capsule SCDF · 705860
  • Bismuth subcitrate / metronidazole / tetracycline hydrochloride Oral Capsule SCDFP · 2648018
  • Bismuth subcitrate / metronidazole / tetracycline Oral Product SCDG · 1161817
  • Bismuth subcitrate / metronidazole / tetracycline Pill SCDG · 1161818
  • Bismuth subcitrate / metronidazole / tetracycline hydrochloride Oral Product SCDGP · 2659155
  • Bismuth subcitrate / metronidazole / tetracycline hydrochloride Pill SCDGP · 2663130

Brand-Name Concepts

  • Bismuth subcitrate 140 MG / metronidazole 125 MG / tetracycline hydrochloride 125 MG [Pylera] SBDC · 1294620
  • Bismuth subcitrate / metronidazole / tetracycline Oral Capsule [Pylera] SBDF · 705864
  • Bismuth subcitrate / metronidazole / tetracycline hydrochloride Oral Capsule [Pylera] SBDFP · 2655683
  • Pylera Oral Product SBDG · 1184086
  • Pylera Pill SBDG · 1184087
  • Pylera BN · 705862

📦 FDA Products & Package NDCs

2 products · 2 package NDCs
2 package NDCs map to RxCUI 1294621 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
61269-0380-12 10 BLISTER PACK in 1 BOX (61269-380-12) / 12 CAPSULE in 1 B... PYLERA H2-Pharma, LLC 2023-10-01
61269-0381-12 10 BLISTER PACK in 1 BOX (61269-381-12) / 12 CAPSULE in 1 B... PYLERA H2-Pharma, LLC 2025-08-18
Observed labelers: H2-Pharma, LLC (2) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

💲 Pricing (NADAC)

NADAC is CMS's National Average Drug Acquisition Cost — roughly what pharmacies pay to buy the drug. It is an acquisition benchmark, not your copay.
Per ea · median
$2.4283
Range $2.4283–$2.4283 · middle 50% $2.4283–$2.4283 · 2 NDCs
Latest compatible distributions from the CMS NADAC file · dataset watermark 2026-07-10. Prices vary by package and pharmacy; a distribution is shown instead of one misleading number. Rows the dataset is silent on carry no price. No zero-cost conclusion should be drawn.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.