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Menthol 105 MG/ML Topical Spray [Biofreeze] — RxCUI 1489074

RxNorm drug concept · Semantic branded drug
RxCUI 1489074 Semantic branded drug · SBD ● Current RxNorm concept 4 FDA products 9 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1489074
Official nameMenthol 105 MG/ML Topical Spray [Biofreeze]
Concept typeSemantic branded drug (SBD)
RxNorm statusCurrent RxNorm concept
Also known asBiofreeze 10.5 % Topical Spray; Biofreeze 105 MG/ML Topical Spray
FDA products mapped4
Package NDCs mapped9
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Menthol: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Menthol is found in a lot of over-the-counter topical products — creams, gels, patches, sprays, and powders. Depending on the product, it's used to temporarily ease minor muscle an...
  • Start with clean, dry skin — free of lotions or creams — before applying the patch. Peel the backing off and press the sticky side firmly to the sore area. Most menthol patches sho...
  • Yes, a mild burning or tingling feeling right after applying a menthol product is common and usually settles down within a few days of regular use. What's not normal is severe burn...
  • Is that burning sensation after I apply it normal?
📖 Read our full Menthol guide →

🕸️ Concept Web — How Menthol 105 MG/ML Topical Spray [Biofreeze] Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Menthol 105 MG/ML Topical Spray [Biofreeze] RxCUI 1489074

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 1

    The active substance itself — no strength, form, or brand attached yet.

    • Menthol 6750
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Biofreeze 1043229
  3. Dose forms 6

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Menthol Topical Spray 377375
    • Menthol Topical Product 1160376
    • Menthol Topical Spray [Biofreeze] 1043231
    • Biofreeze Topical Product 1174337
    • Topical Spray 346165
    • Topical Product 1151122
  4. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 11 of 11 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Menthol 105 MG/ML Topical Spray SCD · 1489073
  • Menthol 105 MG/ML SCDC · 1043455
  • Menthol Topical Spray SCDF · 377375
  • Menthol Topical Product SCDG · 1160376

Brand-Name Concepts

  • Menthol 105 MG/ML [Biofreeze] SBDC · 1043457
  • Menthol Topical Spray [Biofreeze] SBDF · 1043231
  • Biofreeze Topical Product SBDG · 1174337
  • Biofreeze BN · 1043229

📦 FDA Products & Package NDCs

4 products · 9 package NDCs
9 package NDCs map to RxCUI 1489074 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
59316-0114-10 89 mL in 1 BOTTLE (59316-114-10) Biofreeze Reckitt Benckiser LLC 2016-09-19
59316-0114-25 118 mL in 1 BOTTLE, SPRAY (59316-114-25) Biofreeze Reckitt Benckiser LLC 2014-02-19
59316-0114-30 473 mL in 1 BOTTLE, SPRAY (59316-114-30) Biofreeze Reckitt Benckiser LLC 2014-02-19
59316-0120-20 118 mL in 1 BOTTLE (59316-120-20) Biofreeze Professional Reckitt Benckiser LLC 2016-06-03
59316-0120-30 473 mL in 1 BOTTLE (59316-120-30) Biofreeze Professional Reckitt Benckiser LLC 2016-06-03
59316-0833-10 89 mL in 1 BOTTLE (59316-833-10) Biofreeze Reckitt Benckiser LLC 2023-12-01
59316-0833-20 118 mL in 1 BOTTLE (59316-833-20) Biofreeze Reckitt Benckiser LLC 2026-01-01
59316-0834-20 118 mL in 1 BOTTLE (59316-834-20) Biofreeze Professional Reckitt Benckiser LLC 2024-02-01
59316-0834-22 2 BOTTLE in 1 CARTON (59316-834-22) / 118 mL in 1 BOTTLE (5... Biofreeze Professional Reckitt Benckiser LLC 2025-03-15
Observed labelers: Reckitt Benckiser LLC (9) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.