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10 ML methotrexate 25 MG/ML Injection — RxCUI 1655959

RxNorm drug concept · Semantic clinical drug
RxCUI 1655959 Semantic clinical drug · SCD ● Current RxNorm concept 12 FDA products 17 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1655959
Official name10 ML methotrexate 25 MG/ML Injection
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asmethotrexate 250 MG per 10 ML Injection; methotrexate 250 MG in 10 ML Injection
FDA products mapped12
Package NDCs mapped17
Reported Medicaid activity (SDUD)18,307 prescriptions · 48 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Methotrexate Injection: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Yes — for rheumatoid arthritis, psoriasis, and juvenile idiopathic arthritis, once weekly is the correct and intended schedule. This is actually one of the most important safety po...
  • Why am I only taking this once a week? Is that really enough?
  • Common things like mild nausea, tiredness, or mouth soreness are expected and your team can help you manage them. But you should call your doctor immediately — or go to the ER — if...
  • What side effects should I just watch for, versus which ones mean I should call someone right away?
📖 Read our full Methotrexate Injection guide →

🕸️ Concept Web — How 10 ML methotrexate 25 MG/ML Injection Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept 10 ML methotrexate 25 MG/ML Injection RxCUI 1655959

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 1

    The active substance itself — no strength, form, or brand attached yet.

    • Methotrexate 6851
  2. Dose forms 4

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Methotrexate Injection 1655955
    • Methotrexate Injectable Product 1162235
    • Injection 1649574
    • Injectable Product 1151126
  3. Clinical & branded drugs 1

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Methotrexate 25 MG/ML 328406

Showing up to 8 concepts per family — 6 of 6 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Methotrexate 25 MG/ML SCDC · 328406
  • Methotrexate Injection SCDF · 1655955
  • Methotrexate Injectable Product SCDG · 1162235

📦 FDA Products & Package NDCs

12 products · 17 package NDCs
17 package NDCs map to RxCUI 1655959 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00143-9516-01 1 VIAL in 1 BOX (0143-9516-01) / 10 mL in 1 VIAL Methotrexate Hikma Pharmaceuticals USA Inc. 2018-01-05
00143-9517-01 1 VIAL in 1 BOX (0143-9517-01) / 8 mL in 1 VIAL Methotrexate Hikma Pharmaceuticals USA Inc. 2018-01-05
00143-9518-01 1 VIAL in 1 BOX (0143-9518-01) / 4 mL in 1 VIAL Methotrexate Hikma Pharmaceuticals USA Inc. 2018-01-05
00143-9519-10 10 VIAL in 1 CARTON (0143-9519-10) / 2 mL in 1 VIAL Methotrexate Hikma Pharmaceuticals USA Inc. 2017-10-10
00703-3671-01 1 VIAL, SINGLE-DOSE in 1 CARTON (0703-3671-01) / 2 mL in 1... Methotrexate Teva Parenteral Medicines, Inc. 2018-06-08
00703-3675-01 1 VIAL, SINGLE-DOSE in 1 CARTON (0703-3675-01) / 10 mL in 1... Methotrexate Teva Parenteral Medicines, Inc. 2012-08-01
00703-3678-01 1 VIAL, SINGLE-DOSE in 1 CARTON (0703-3678-01) / 40 mL in 1... Methotrexate Teva Parenteral Medicines, Inc. 2012-08-01
16729-0277-03 1 VIAL in 1 CARTON (16729-277-03) / 10 mL in 1 VIAL Methotrexate Accord Healthcare, Inc. 2014-03-07
16729-0277-30 1 VIAL in 1 CARTON (16729-277-30) / 2 mL in 1 VIAL Methotrexate Accord Healthcare, Inc. 2014-03-07
16729-0277-35 1 VIAL in 1 CARTON (16729-277-35) / 40 mL in 1 VIAL Methotrexate Accord Healthcare, Inc. 2014-03-07
55150-0510-01 1 VIAL, SINGLE-DOSE in 1 CARTON (55150-510-01) / 2 mL in 1... METHOTREXATE Eugia US LLC 2024-09-11
55150-0510-05 5 VIAL, SINGLE-DOSE in 1 CARTON (55150-510-05) / 2 mL in 1... METHOTREXATE Eugia US LLC 2024-09-11
55150-0511-01 1 VIAL, SINGLE-DOSE in 1 CARTON (55150-511-01) / 4 mL in 1... METHOTREXATE Eugia US LLC 2024-09-11
55150-0511-10 10 VIAL, SINGLE-DOSE in 1 CARTON (55150-511-10) / 4 mL in 1... METHOTREXATE Eugia US LLC 2024-09-11
55150-0512-01 1 VIAL, SINGLE-DOSE in 1 CARTON (55150-512-01) / 8 mL in 1... METHOTREXATE Eugia US LLC 2024-09-11
55150-0512-10 10 VIAL, SINGLE-DOSE in 1 CARTON (55150-512-10) / 8 mL in 1... METHOTREXATE Eugia US LLC 2024-09-11
55150-0513-01 1 VIAL in 1 CARTON (55150-513-01) / 10 mL in 1 VIAL METHOTREXATE Eugia US LLC 2024-09-11
Observed labelers: Eugia US LLC (7) · Hikma Pharmaceuticals USA Inc. (4) · Accord Healthcare, Inc. (3) · Teva Parenteral Medicines, Inc. (3) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🧾 Billing Codes (HCPCS)

Medical billing codes (HCPCS "J-codes") that connect to this concept's packages — used mostly when a clinic or hospital bills for a drug it administers. Each code links to its full billing page.
CodeDescriptorMapped packagesSources
J9260 Inj methotrexate sodium 50mg 6 CMS
⚠ A crosswalk is not coverage: an NDC↔HCPCS mapping does not guarantee any payer covers or pays the code. Always verify the current payer policy before billing.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.