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Sacubitril 97 MG / valsartan 103 MG Oral Tablet [Entresto] — RxCUI 1656356

Name: Sacubitril 97 MG / valsartan 103 MG Oral Tablet [Entresto] (RxCUI 1656356)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic branded drug

RxCUI 1656356 Semantic branded drug · SBD ● Current RxNorm concept 8 FDA products 11 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1656356

Official nameSacubitril 97 MG / valsartan 103 MG Oral Tablet [Entresto]

Concept typeSemantic branded drug (SBD)

RxNorm statusCurrent RxNorm concept

Also known asEntresto 97 MG / 103 MG Oral Tablet

FDA products mapped8

Package NDCs mapped11

Reported Medicaid activity (SDUD)657,545 prescriptions · 52 state & territory Medicaid programs · latest period Q4 2025

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Valsartan and Sacubitril: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

Sacubitril and valsartan works on two fronts at once. One part (sacubitril) helps your body's own protective heart hormones stick around longer, which helps your kidneys get rid of...
What exactly is this medication supposed to do for my heart failure?
That's a really important question. A few combinations need to be avoided or watched carefully. You should never take this with an ACE inhibitor like lisinopril or enalapril at the...
Can I take it with my other medications? I'm also on ibuprofen sometimes for pain.

📖 Read our full Valsartan and Sacubitril guide →

🕸️ Concept Web — How Sacubitril 97 MG / valsartan 103 MG Oral Tablet... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Sacubitril 97 MG / valsartan 103 MG Oral Tablet [Entresto] RxCUI 1656356 Semantic branded drug · SBD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 3

The active substance itself — no strength, form, or brand attached yet.
- Sacubitril 1656328 IN
- Valsartan 69749 IN
- Sacubitril / valsartan 1656339 MIN
Brand names 1

The same medicine's trade names. A brand name alone says nothing about strength or form.
- Entresto 1656341 BN
Dose forms 9

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Sacubitril / valsartan Oral Tablet 1656338 SCDF
- Sacubitril / valsartan Oral Product 1656336 SCDG
- Sacubitril / valsartan Pill 1656337 SCDG
- Sacubitril / valsartan Oral Tablet [Entresto] 1656343 SBDF
- Entresto Oral Product 1656344 SBDG
- Entresto Pill 1656345 SBDG
- Oral Tablet 317541 DF
- Oral Product 1151131 DFG
- +1 more in this family
Clinical & branded drugs 4

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Sacubitril 97 MG / valsartan 103 MG Oral Tablet 1656354 SCD
- Sacubitril 97 MG 1656352 SCDC
- Valsartan 103 MG 1656353 SCDC
- Sacubitril 97 MG / valsartan 103 MG [Entresto] 1656355 SBDC

Showing up to 8 concepts per family — 16 of 17 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Sacubitril 97 MG / valsartan 103 MG Oral Tablet SCD · 1656354
Sacubitril 97 MG SCDC · 1656352
Valsartan 103 MG SCDC · 1656353
Sacubitril / valsartan Oral Tablet SCDF · 1656338
Sacubitril / valsartan Oral Product SCDG · 1656336
Sacubitril / valsartan Pill SCDG · 1656337

Brand-Name Concepts

Sacubitril 97 MG / valsartan 103 MG [Entresto] SBDC · 1656355
Sacubitril / valsartan Oral Tablet [Entresto] SBDF · 1656343
Entresto Oral Product SBDG · 1656344
Entresto Pill SBDG · 1656345
Entresto BN · 1656341

📦 FDA Products & Package NDCs

8 products · 11 package NDCs

11 package NDCs map to RxCUI 1656356 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
00078-0659-20	60 TABLET, FILM COATED in 1 BOTTLE (0078-0659-20)	ENTRESTO	Novartis Pharmaceuticals Corporation	2015-07-07
00078-0659-67	180 TABLET, FILM COATED in 1 BOTTLE (0078-0659-67)	ENTRESTO	Novartis Pharmaceuticals Corporation	2015-07-07
00078-0696-20	60 TABLET, FILM COATED in 1 BOTTLE (0078-0696-20)	ENTRESTO	Novartis Pharmaceuticals Corporation	2015-07-07
00078-0696-67	180 TABLET, FILM COATED in 1 BOTTLE (0078-0696-67)	ENTRESTO	Novartis Pharmaceuticals Corporation	2015-07-07
00078-0777-20	60 TABLET, FILM COATED in 1 BOTTLE (0078-0777-20)	ENTRESTO	Novartis Pharmaceuticals Corporation	2015-07-07
00078-0777-67	180 TABLET, FILM COATED in 1 BOTTLE (0078-0777-67)	ENTRESTO	Novartis Pharmaceuticals Corporation	2015-07-07
00078-1231-20	60 PELLET in 1 BOTTLE (0078-1231-20)	ENTRESTO	Novartis Pharmaceuticals Corporation	2024-04-12
00078-1238-20	60 PELLET in 1 BOTTLE (0078-1238-20)	ENTRESTO	Novartis Pharmaceuticals Corporation	2024-04-12
00078-9659-50	28 TABLET, FILM COATED in 1 BOTTLE (0078-9659-50)	ENTRESTO	Novartis Pharmaceuticals Corporation	2018-08-23
00078-9777-50	28 TABLET, FILM COATED in 1 BOTTLE (0078-9777-50)	ENTRESTO	Novartis Pharmaceuticals Corporation	2018-08-23
71610-0807-37	3120 TABLET, FILM COATED in 1 BOTTLE (71610-807-37)	ENTRESTO	Aphena Pharma Solutions - Tennessee, LLC	2024-03-22

Observed labelers: Novartis Pharmaceuticals Corporation (10) · Aphena Pharma Solutions - Tennessee, LLC (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.