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Piperacillin 3000 MG / tazobactam 375 MG Injection — RxCUI 1659137

RxNorm drug concept · Semantic clinical drug
RxCUI 1659137 Semantic clinical drug · SCD ● Current RxNorm concept 59 FDA products 59 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1659137
Official namePiperacillin 3000 MG / tazobactam 375 MG Injection
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known aspiperacillin / tazobactam 3.375 GM Injection; piperacillin (as piperacillin sodium) 3000 MG / tazobactam (as tazobactam sodium) 375 MG Injection
FDA products mapped59
Package NDCs mapped59
Reported Medicaid activity (SDUD)52,354 prescriptions · 51 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Piperacillin and Tazobactam Injection: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Piperacillin and tazobactam is a powerful combination antibiotic used for serious bacterial infections that need IV treatment — things like a ruptured appendix with infection, a ba...
  • What is this antibiotic actually treating — why did my doctor choose this one?
  • It's given through an IV line directly into your vein, infused slowly over 30 minutes. Most patients receive it every 6 to 8 hours, and a typical course lasts 7 to 14 days dependin...
  • How is this medication given, and how long will I need it?
📖 Read our full Piperacillin and Tazobactam Injection guide →

🕸️ Concept Web — How Piperacillin 3000 MG / tazobactam 375 MG Injecti... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Piperacillin 3000 MG / tazobactam 375 MG Injection RxCUI 1659137

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 3

    The active substance itself — no strength, form, or brand attached yet.

    • Piperacillin 8339
    • Tazobactam 37617
    • Piperacillin / tazobactam 74169
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Zosyn 74170
  3. Dose forms 6

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Piperacillin / tazobactam Injection 1659130
    • Piperacillin / tazobactam Injectable Product 1159278
    • Piperacillin / tazobactam Injection [Zosyn] 1659133
    • Zosyn Injectable Product 1186325
    • Injection 1649574
    • Injectable Product 1151126
  4. Clinical & branded drugs 4

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 14 of 14 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Piperacillin 3000 MG SCDC · 1659135
  • Tazobactam 375 MG SCDC · 1659136
  • Piperacillin / tazobactam Injection SCDF · 1659130
  • Piperacillin / tazobactam Injectable Product SCDG · 1159278

Brand-Name Concepts

📦 FDA Products & Package NDCs

59 products · 59 package NDCs
59 package NDCs map to RxCUI 1659137 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
81284-0151-10 10 VIAL, SINGLE-DOSE in 1 CARTON (81284-151-10) / 10 mL in... PIPERACILLIN AND TAZOBACTAM Provepharm Inc. 2019-08-01
81284-0152-10 10 VIAL, SINGLE-DOSE in 1 CARTON (81284-152-10) / 15 mL in... PIPERACILLIN AND TAZOBACTAM Provepharm Inc. 2019-08-01
81284-0153-10 10 VIAL, SINGLE-DOSE in 1 CARTON (81284-153-10) / 20 mL in... PIPERACILLIN AND TAZOBACTAM Provepharm Inc. 2019-08-01
83270-0301-10 10 VIAL, SINGLE-USE in 1 CARTON (83270-301-10) / 10 mL in 1... piperacillin and tazobactam ONESOURCE SPECIALTY PHARMA LIMITED 2016-06-30
83270-0302-10 10 VIAL, SINGLE-USE in 1 CARTON (83270-302-10) / 15 mL in 1... piperacillin and tazobactam ONESOURCE SPECIALTY PHARMA LIMITED 2015-08-14
83270-0303-10 10 VIAL, SINGLE-USE in 1 CARTON (83270-303-10) / 20 mL in 1... piperacillin and tazobactam ONESOURCE SPECIALTY PHARMA LIMITED 2016-06-30
83634-0104-20 10 VIAL, SINGLE-DOSE in 1 CARTON (83634-104-20) / 10 mL in... Piperacillin and Tazobactam Avenacy, LLC 2025-02-01
83634-0105-30 10 VIAL, SINGLE-DOSE in 1 CARTON (83634-105-30) / 15 mL in... Piperacillin and Tazobactam Avenacy, LLC 2025-02-01
83634-0106-50 10 VIAL, SINGLE-DOSE in 1 CARTON (83634-106-50) / 20 mL in... Piperacillin and Tazobactam Avenacy, LLC 2025-02-01
Observed labelers: Fresenius Kabi USA, LLC (15) · Eugia US LLC (6) · Civica, Inc. (4) · Apotex Corp. (3) · Avenacy, LLC (3) · B. Braun Medical Inc. (3) · +9 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🧾 Billing Codes (HCPCS)

Medical billing codes (HCPCS "J-codes") that connect to this concept's packages — used mostly when a clinic or hospital bills for a drug it administers. Each code links to its full billing page.
CodeDescriptorMapped packagesSources
J2543 Piperacillin/tazobactam 37 CMS
⚠ A crosswalk is not coverage: an NDC↔HCPCS mapping does not guarantee any payer covers or pays the code. Always verify the current payer policy before billing.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.